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Author: Maurice Goeldner
Publisher: John Wiley & Sons
ISBN: 3527605541
Category : Science
Languages : en
Pages : 584
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Book Description
With contributions by more than 30 expert researchers, this handbook covers the whole spectrum from chemistry to cell biology and from theory to application. In so doing, it deals with a broad range of topics from the chemistry and biophysics of caged compounds to their application in time-resolved studies, comparing the properties of different caging groups. The authors describe in detail light-activation of proteins as well as nucleic acids, while a special section is devoted to multiphoton phototriggers. A must-have for every biochemist, biophysicist and molecular biologist developing and working with these novel methods.
Author: Maurice Goeldner
Publisher: John Wiley & Sons
ISBN: 3527605541
Category : Science
Languages : en
Pages : 584
Get Book Here
Book Description
With contributions by more than 30 expert researchers, this handbook covers the whole spectrum from chemistry to cell biology and from theory to application. In so doing, it deals with a broad range of topics from the chemistry and biophysics of caged compounds to their application in time-resolved studies, comparing the properties of different caging groups. The authors describe in detail light-activation of proteins as well as nucleic acids, while a special section is devoted to multiphoton phototriggers. A must-have for every biochemist, biophysicist and molecular biologist developing and working with these novel methods.
Author: Stephen P. Ellner
Publisher: Princeton University Press
ISBN: 1400840961
Category : Science
Languages : en
Pages : 352
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Book Description
From controlling disease outbreaks to predicting heart attacks, dynamic models are increasingly crucial for understanding biological processes. Many universities are starting undergraduate programs in computational biology to introduce students to this rapidly growing field. In Dynamic Models in Biology, the first text on dynamic models specifically written for undergraduate students in the biological sciences, ecologist Stephen Ellner and mathematician John Guckenheimer teach students how to understand, build, and use dynamic models in biology. Developed from a course taught by Ellner and Guckenheimer at Cornell University, the book is organized around biological applications, with mathematics and computing developed through case studies at the molecular, cellular, and population levels. The authors cover both simple analytic models--the sort usually found in mathematical biology texts--and the complex computational models now used by both biologists and mathematicians. Linked to a Web site with computer-lab materials and exercises, Dynamic Models in Biology is a major new introduction to dynamic models for students in the biological sciences, mathematics, and engineering.
Author: Peter Turchin
Publisher: Princeton University Press
ISBN: 0691090211
Category : Science
Languages : en
Pages : 470
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Book Description
Why do organisms become extremely abundant one year and then seem to disappear a few years later? Why do population outbreaks in particular species happen more or less regularly in certain locations, but only irregularly (or never at all) in other locations? Complex population dynamics have fascinated biologists for decades. By bringing together mathematical models, statistical analyses, and field experiments, this book offers a comprehensive new synthesis of the theory of population oscillations. Peter Turchin first reviews the conceptual tools that ecologists use to investigate population oscillations, introducing population modeling and the statistical analysis of time series data. He then provides an in-depth discussion of several case studies--including the larch budmoth, southern pine beetle, red grouse, voles and lemmings, snowshoe hare, and ungulates--to develop a new analysis of the mechanisms that drive population oscillations in nature. Through such work, the author argues, ecologists can develop general laws of population dynamics that will help turn ecology into a truly quantitative and predictive science. Complex Population Dynamics integrates theoretical and empirical studies into a major new synthesis of current knowledge about population dynamics. It is also a pioneering work that sets the course for ecology's future as a predictive science.
Author: Michael Small
Publisher: CRC Press
ISBN: 1439853363
Category : Mathematics
Languages : en
Pages : 286
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Book Description
From the spontaneous rapid firing of cortical neurons to the spatial diffusion of disease epidemics, biological systems exhibit rich dynamic behaviour over a vast range of time and space scales. Unifying many of these diverse phenomena, Dynamics of Biological Systems provides the computational and mathematical platform from which to understand the underlying processes of the phenomena. Through an extensive tour of various biological systems, the text introduces computational methods for simulating spatial diffusion processes in excitable media, such as the human heart, as well as mathematical tools for dealing with systems of nonlinear ordinary and partial differential equations, such as neuronal activation and disease diffusion. The mathematical models and computer simulations offer insight into the dynamics of temporal and spatial biological systems, including cardiac pacemakers, artificial electrical defibrillation, pandemics, pattern formation, flocking behaviour, the interaction of autonomous agents, and hierarchical and structured network topologies. Tools from complex systems and complex networks are also presented for dealing with real phenomenological systems. With exercises and projects in each chapter, this classroom-tested text shows students how to apply a variety of mathematical and computational techniques to model and analyze the temporal and spatial phenomena of biological systems. MATLAB® implementations of algorithms and case studies are available on the author’s website.
Author: Joshua M. Epstein
Publisher: CRC Press
ISBN: 0429973039
Category : Mathematics
Languages : en
Pages : 132
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Book Description
This book is based on a series of lectures on mathematical biology, the essential dynamics of complex and crucially important social systems, and the unifying power of mathematics and nonlinear dynamical systems theory.
Author: Torben Martinussen
Publisher: Springer Science & Business Media
ISBN: 0387339604
Category : Medical
Languages : en
Pages : 471
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Book Description
This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and alternative models with the aim of describing time-varying effects of explanatory variables. Use of the suggested models and methods is illustrated on real data examples, using the R-package timereg developed by the authors, which is applied throughout the book with worked examples for the data sets.
Author: Carl M. Cohen
Publisher: CSHL Press
ISBN: 0879698160
Category : Comportement organisationnel
Languages : en
Pages : 184
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Book Description
"Lab Dynamics is a book about the challenges to doing science and dealing with the individuals involved, including oneself. The authors, a scientist and a psychotherapist, draw on principles of group and behavioral psychology but speak to scientists in their own language about their own experiences. They offer in-depth, practical advice, real-life examples, and exercises tailored to scientific and technical workplaces on topics as diverse as conflict resolution, negotiation, dealing with supervision, working with competing peers, and making the transition from academia to industry." "This is a uniquely valuable contribution to the scientific literature, on a subject of direct importance to lab heads, postdocs, and students. It is also required reading for senior staff concerned about improving efficiency and effectiveness in academic and industrial research."--BOOK JACKET
Author: Cang Hui
Publisher: Oxford University Press
ISBN: 0191062537
Category : Science
Languages : en
Pages : 607
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Book Description
Humans have moved organisms around the world for centuries but it is only relatively recently that invasion ecology has grown into a mainstream research field. This book examines both the spread and impact dynamics of invasive species, placing the science of invasion biology on a new, more rigorous, theoretical footing, and proposing a concept of adaptive networks as the foundation for future research. Biological invasions are considered not as simple actions of invaders and reactions of invaded ecosystems, but as co-evolving complex adaptive systems with emergent features of network complexity and invasibility. Invasion Dynamics focuses on the ecology of invasive species and their impacts in recipient social-ecological systems. It discusses not only key advances and challenges within the traditional domain of invasion ecology, but introduces approaches, concepts, and insights from many other disciplines such as complexity science, systems science, and ecology more broadly. It will be of great value to invasion biologists analyzing spread and/or impact dynamics as well as other ecologists interested in spread processes or habitat management.
Author: Keith Moffat
Publisher: John Wiley & Sons
ISBN: 1119696305
Category : Science
Languages : en
Pages : 292
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Book Description
Dynamics and Kinetics in Structural Biology Understand the latest experimental tools in structural biology with this pioneering work Structural biology seeks to understand the chemical mechanisms and functions of biological molecules, such as proteins, based on their atomic structures. Until recently, these structures have been studied only statically, using procedures which deliberately freeze atomic motion. However, freezing eliminates the rapid structural motions so essential to biological activity and function; the molecules are inactive. But with the recent development of X-ray free electron laser (XFEL) sources, efforts to conduct dynamic experiments have expanded using the principles of dynamics and kinetics to capture active biological molecules as they function. Dynamics and Kinetics in Structural Biology promotes the development of these experiments and their successful application. It grounds readers in the foundational principles of dynamics and kinetics; proceeds through extended discussions of experimental procedures and data analysis techniques; and explores experimental frontiers in structural dynamics. The book will aid researchers to gather and interpret cutting-edge data on the dynamic structure of biological molecules, under conditions where they retain their biological functions. Dynamics and Kinetics in Structural Biology offers readers: Authorship by founding figures in the field In-depth presentation of time-resolved X-ray crystallography, solution scattering, and more A pioneering contribution to a rapidly developing field of study Dynamics and Kinetics in Structural Biology is essential reading for graduate students, scientists, researchers and industry professionals engaged in structural studies of biological systems. Industry professionals considering dynamic studies in the development of new product lines will also benefit.
Author: Corrado Priami
Publisher: World Scientific
ISBN: 1783266899
Category : Science
Languages : en
Pages : 431
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Book Description
Modeling is fast becoming fundamental to understanding the processes that define biological systems. High-throughput technologies are producing increasing quantities of data that require an ever-expanding toolset for their effective analysis and interpretation. Analysis of high-throughput data in the context of a molecular interaction network is particularly informative as it has the potential to reveal the most relevant network modules with respect to a phenotype or biological process of interest.Analysis of Biological Systems collects classical material on analysis, modeling and simulation, thereby acting as a unique point of reference. The joint application of statistical techniques to extract knowledge from big data and map it into mechanistic models is a current challenge of the field, and the reader will learn how to build and use models even if they have no computing or math background. An in-depth analysis of the currently available technologies, and a comparison between them, is also included. Unlike other reference books, this in-depth analysis is extended even to the field of language-based modeling. The overall result is an indispensable, self-contained and systematic approach to a rapidly expanding field of science.
