Author: Hans-Joachim Bungartz
Publisher: Springer Nature
ISBN: 3030479560
Category : Computers
Languages : en
Pages : 624
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Book Description
This open access book summarizes the research done and results obtained in the second funding phase of the Priority Program 1648 "Software for Exascale Computing" (SPPEXA) of the German Research Foundation (DFG) presented at the SPPEXA Symposium in Dresden during October 21-23, 2019. In that respect, it both represents a continuation of Vol. 113 in Springer’s series Lecture Notes in Computational Science and Engineering, the corresponding report of SPPEXA’s first funding phase, and provides an overview of SPPEXA’s contributions towards exascale computing in today's sumpercomputer technology. The individual chapters address one or more of the research directions (1) computational algorithms, (2) system software, (3) application software, (4) data management and exploration, (5) programming, and (6) software tools. The book has an interdisciplinary appeal: scholars from computational sub-fields in computer science, mathematics, physics, or engineering will find it of particular interest.
Author: Betsy Morgan
Publisher: Inspirations Studios
ISBN: 9780648287360
Category : Cross-stitch
Languages : en
Pages : 0
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Book Description
Author:
Publisher:
ISBN:
Category : Trademarks
Languages : en
Pages : 536
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Book Description
Author: Jong Hoon Park
Publisher: Springer
ISBN: 9811020418
Category : Medical
Languages : en
Pages : 128
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Book Description
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Author: Kate McMullan
Publisher: ABDO
ISBN: 9781599613789
Category : Juvenile Fiction
Languages : en
Pages : 116
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Book Description
After accidentally killing a dragon, Wiglaf hopes his friends at Dragon Slayers' Academy will be able to help him prove himself a hero when he faces that dragon's mother, Seetha, the Beast from the East. Follow Wiglaf's adventures at Dragon Slayers' Academy as he discovers more about his past and what the future holds for him.
Author: Vanessa-Ann Collection (Firm)
Publisher:
ISBN: 9780696023217
Category : Crafts & Hobbies
Languages : en
Pages : 152
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Book Description
Author: Richard Pray
Publisher:
ISBN: 9781572183346
Category : Building
Languages : en
Pages : 0
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Book Description
"Includes free estimating software download"--Cover.
Author: Janon Co [From Old Catalog]
Publisher: Franklin Classics
ISBN: 9780342551170
Category :
Languages : en
Pages : 74
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Book Description
This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Author: Celeste Johnston
Publisher: Better Day Books
ISBN: 9780764361234
Category : Crafts & Hobbies
Languages : en
Pages : 168
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Book Description
"Inside you'll find 12 fresh projects featuring beautiful plants, flowers, and botanicals. Each one, includes step-by-step instructions, a quick reference guide to the colors and stitches, full-size patterns, and helpful tips... Enjoy the fulfilling, creative, and therapeutic process of embroidery with these modern, inviting, and uplifting designs!"--Back cover.
Author: Leisure Arts, Inc
Publisher: Oxmoor House
ISBN: 9781574861228
Category : Christmas decorations
Languages : en
Pages : 0
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Book Description
Cross stitchers will definitely want to add this collection to their cross stitch library. Echoing sentiments of days gone by, more than 60 projects include Christmas stockings and coordinating ornaments, embellished clothing, pillows, afghans, decorative baskets, and more. Readers everywhere will delight in these special holiday projects.
