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Author: Salvador Mercer
Publisher: Diamond Star Publishing
ISBN:
Category :
Languages : en
Pages : 333
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Book Description
What lies on the dark side of the moon could change the course of humanity forever. When a Chinese rover discovers an alien technology on the dark side of the moon, it is up to Richard 'Rock' Crandon and his NASA team of scientists and engineers to devise a way to return before the Chinese and Russians. Forced to deal with bureaucratic oversight and a complex team of personalities, Rock Crandon pushes his team to their limits. With pressure mounting, the world is pushed closer to conflict and war as the NASA team finds itself seriously behind in the newly initiated space race. The future of mankind, its ideological and technological advances are at stake, as the world's super powers race to discover what lies on the dark side of the moon. Who will get there first, and at what cost?
Author: Anuj Karpatne
Publisher: CRC Press
ISBN: 1000598101
Category : Business & Economics
Languages : en
Pages : 442
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Book Description
Given their tremendous success in commercial applications, machine learning (ML) models are increasingly being considered as alternatives to science-based models in many disciplines. Yet, these "black-box" ML models have found limited success due to their inability to work well in the presence of limited training data and generalize to unseen scenarios. As a result, there is a growing interest in the scientific community on creating a new generation of methods that integrate scientific knowledge in ML frameworks. This emerging field, called scientific knowledge-guided ML (KGML), seeks a distinct departure from existing "data-only" or "scientific knowledge-only" methods to use knowledge and data at an equal footing. Indeed, KGML involves diverse scientific and ML communities, where researchers and practitioners from various backgrounds and application domains are continually adding richness to the problem formulations and research methods in this emerging field. Knowledge Guided Machine Learning: Accelerating Discovery using Scientific Knowledge and Data provides an introduction to this rapidly growing field by discussing some of the common themes of research in KGML using illustrative examples, case studies, and reviews from diverse application domains and research communities as book chapters by leading researchers. KEY FEATURES First-of-its-kind book in an emerging area of research that is gaining widespread attention in the scientific and data science fields Accessible to a broad audience in data science and scientific and engineering fields Provides a coherent organizational structure to the problem formulations and research methods in the emerging field of KGML using illustrative examples from diverse application domains Contains chapters by leading researchers, which illustrate the cutting-edge research trends, opportunities, and challenges in KGML research from multiple perspectives Enables cross-pollination of KGML problem formulations and research methods across disciplines Highlights critical gaps that require further investigation by the broader community of researchers and practitioners to realize the full potential of KGML
Author: DK
Publisher: Penguin
ISBN: 0756689384
Category : Transportation
Languages : en
Pages : 362
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Book Description
From the first motor cars and classic cars to today's supercars and Formula 1, this is the ultimate book about the history of the car. Packed with stunning photography, and featuring more than 2,000 cars, Car shows you how cars have evolved around the world over the the last 130 years, and their impact on society as objects of curiosity, symbols of status and luxury, and items of necessity. Extensive catalogues showcase the most important marques and models, organized in categories such as sports cars, convertibles, and city compacts. The book also features virtual photographic tours of some of the most iconic cars from each era such as the Rolls Royce Silver Ghost, Ford Model T, Lamborghini Countach, and Ferrari F40, while cross-sections of key engines explore the driving force behind them. Lavishly illustrated feature spreads detail the stories of the men, machines, and magic that helped create the car world's most famous marques and made brands such as Porsche, Mercedes-Benz, Aston Martin, and Cadillac household names. If you love cars, then you'll love Car. It is simply a must-have title for all car enthusiasts.
Author: David Cavalla
Publisher: Royal Society of Chemistry
ISBN: 1839163402
Category : Medical
Languages : en
Pages : 350
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Book Description
Drug repurposing is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process. Three repurposed drugs can be brought to market for the same cost as one new chemical entity; and they can also be identified more quickly, an important benefit for patients whose diseases are progressing faster than therapeutic innovation. But repurposing also requires a fresh look at configuring pharmaceutical R&D, considering clinical, regulatory and patent issues much earlier than would otherwise be the case; a holistic gedanken experiment almost needs to be undertaken at the very start of any repurposing development. In addition to new ways of thinking, the discovery of repurposing opportunities can take advantage of artificial intelligence techniques to match the perfect new use for an existing drug. And while repurposing of medicines has been in the mind of every doctor since Hypocrates, modern clinical practice will simply have to adapt to new repurposing techniques in an age where the number of known diseases is increasing much faster than the healthcare dollars available.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 360
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Book Description
BLACK ENTERPRISE is the ultimate source for wealth creation for African American professionals, entrepreneurs and corporate executives. Every month, BLACK ENTERPRISE delivers timely, useful information on careers, small business and personal finance.
Author: United States. Department of State. Bureau of Rolls and Library
Publisher:
ISBN:
Category : Archives
Languages : en
Pages : 840
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Book Description
Author: Charles MacLean
Publisher: Simon and Schuster
ISBN: 1620879042
Category : Cooking
Languages : en
Pages : 668
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Book Description
Individual distilleries give their whiskies unique characteristics. These characteristics do not arise magically (as was once thought), nor are they the result solely of the region (as is still thought, by some). They have their roots in the craft and custom of the distillery and of the district in which it is located, but the key influences upon flavor are the distilling equipment itself, how it is operated, and how the spirit is matured. For the first time, Whiskypedia explores the flavor and character of every malt whisky distilled in Scotland with reference to how it is made. Introductory sections explain the contribution made by each stage of production and maturation, to elucidate the detailed notes about how malt whisky is made at each distillery. The distillery entries also provide historical notes and quirky facts. Malt whisky is the quintessential “spirit of place,” and this element of the story has been captured by John MacPherson's camera in specially commissioned images which compliment the text.
Author: Lyn Jones
Publisher: Royal Society of Chemistry
ISBN: 1849737150
Category : Science
Languages : en
Pages : 331
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Book Description
This book illustrates the successful partnership of chemistry and biology to advance successful biotherapeutic modalities. Molecular design to create function is common to both chemical and molecular biology, and this text highlights recent developments from these disciplines that have delivered drugs, clinical candidates or significantly advanced biotherapeutic approaches. Biotherapeutics are often considered to be beyond the reach of the medicinal chemist, but this book demonstrates that chemistry has an essential role in the future success of this area, by explaining and describing the chemical biology technologies that underpin specific therapeutic advances and demonstrating the unique value of molecular design and understanding. Covering topics such as selective protein modification, immunopharmacotherapy, chemically programmed vaccinations, nanobodies and antibodies, this book provides essential reading for medicinal and pharmaceutical chemists working in both industry and academia.
Author: Cathy Pickens
Publisher: Arcadia Publishing
ISBN: 1439667667
Category : History
Languages : en
Pages : 168
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Book Description
A thrilling account of a hundred years of sensational and sinister deeds that marked and shaped one southern town. Crimes that captivated attention in the Charlotte area over the years run the gamut from missing people to the wrongly accused. This collection of headline stories features violent motorcycle gangs, crusading mothers, a fraudster who claimed a president was poisoned by his wife, a serial killer who broke all the rules and even a man who made Bigfoot. With a mystery novelist's ear for a good tale, Cathy Pickens presents more than a century of sensational sinister deeds that marked this diverse and dynamic city.
Author: Glynis Nicholls
Publisher: Royal Society of Chemistry
ISBN: 1782620699
Category : Medical
Languages : en
Pages : 494
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Book Description
Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. In this first volume on Drug Transporters, the current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics are comprehensively reviewed. The second volume of the book is specifically dedicated to emerging science and technologies, highlighting potential areas for future advances within the drug transporter field. The topics covered in both volumes ensure that all relevant aspects of transporters are described across the drug development process, from in silico models and preclinical tools through to the potential impact of transporters in the clinic. Contributions are included from expert leaders in the field, at-the-bench industrial scientists, renowned academics and international regulators. Case studies and emerging developments are highlighted, together with the merits and limitations of the available methods and tools, and extensive references to reviews on specific in-depth topics are also included for those wishing to pursue their knowledge further. As such, this text serves as an essential handbook of information for postgraduate students, academics, industrial scientists and regulators who wish to understand the role of transporters in absorption, distribution, metabolism, and excretion processes. In addition, it is also a useful reference tool on the models and calculations necessary to predict their effect on human pharmacokinetics and pharmacodynamics.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :
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Book Description
First multi-year cumulation covers six years: 1965-70.
