Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in the United States

Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in the United States PDF Author: John P. Giesy
Publisher: Springer Science & Business Media
ISBN: 3319038656
Category : Science
Languages : en
Pages : 282

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Book Description
Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in the United States

Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in the United States PDF Author: John P. Giesy
Publisher: Springer Science & Business Media
ISBN: 3319038656
Category : Science
Languages : en
Pages : 282

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Book Description
Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Gut Microbiota in Neurologic and Visceral Diseases

Gut Microbiota in Neurologic and Visceral Diseases PDF Author: Tahira Farooqui
Publisher: Academic Press
ISBN: 0128210400
Category : Medical
Languages : en
Pages : 388

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Book Description
Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer's disease, Parkinson's, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders. - Reviews the relationship between gut microbiome, diseases and disorders - Discusses the relationship between diet, microbiota and inflammation - Includes neurodegenerative, neuropsychiatric and cardiovascular disorders - Covers diabetes, obesity and metabolic disorders - Identifies molecular mechanisms and signal transduction processes - Encompasses dietary fiber, fat, prebiotics and probiotics

Toxicology of Organophosphate and Carbamate Compounds

Toxicology of Organophosphate and Carbamate Compounds PDF Author: Ramesh C Gupta
Publisher: Academic Press
ISBN: 0080543103
Category : Technology & Engineering
Languages : en
Pages : 781

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Book Description
This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. - Describes everything you need to know about Organophosphates and Carbamates - Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants - Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates - Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases - Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity - Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis - Provides in vitro and in vivo models for neurotoxicity testing - Integrates knowledge of studies in lab animals and humans - Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues - Describes management of Anticholinesterase poisoning in humans

UV-visible Spectrophotometry of Water and Wastewater

UV-visible Spectrophotometry of Water and Wastewater PDF Author: Olivier Thomas
Publisher: Elsevier
ISBN: 0080489842
Category : Science
Languages : en
Pages : 373

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Book Description
UV-Visible Spectrophotometry of Water and Wastewater is the first book dedicated to the use of UV spectrophotometry for water and wastewater quality monitoring. Using practical examples the reader is shown how this technique can be a source of new methods of characterization and measurement. Easy and fast to run, this simple and robust analytical technique must be considered as one of the best ways to obtain a quantitative estimation of specific or aggregate parameters (eg. Nitrate, TOC), and simultaneously qualitative information on the global composition of water and its variation.* First electronic library of UV-spectra providing data readily available for researchers and users* Provides a theoretical basis for further research in the field of spectra exploitation* Contains helpful practical applications

Metabolic Pathways of Agrochemicals

Metabolic Pathways of Agrochemicals PDF Author: Terry R Roberts
Publisher: Royal Society of Chemistry
ISBN: 1847551386
Category : Technology & Engineering
Languages : en
Pages : 872

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Book Description
This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.

Best Synthetic Methods

Best Synthetic Methods PDF Author: Chris Timperley
Publisher: Newnes
ISBN: 0080982247
Category : Technology & Engineering
Languages : en
Pages : 787

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Book Description
Best Synthetic Methods: Organophosphorus (V) Chemistry provides systematic coverage of the most common classes of pentavalent organophosphorus compounds and reagents (including phosphonyl, phosphoryl, and organophosphates), and allows researchers an easy point of entry into this complex and economically important field. The book follows the Best Synthetic Methods format, containing practical methods, synthetic tips, and shortcuts. Where relevant, articles include toxicity data and historical context for the reactions. Typical analytical and spectroscopic data are also presented to enable scientists to identify key compound characteristics. The book is a valuable companion to research chemists in both academia and industry, summarizing the best practical methods (often originating in difficult-to-access, foreign-language primary literature) in one place. It is ideally suited for those working on industrial applications of these compounds, including insecticides, herbicides, flame retardants, and plasticizers. - Includes a mixture of tried and tested, historical methods that are proven to work, alongside new methods to provide scientists with a quick, time-saving resource of reliable methods - Includes tips and tricks to get reactions to work; important information often missing from other sources - Includes key analytical data for compounds, so scientists have one handy resource to select, perform, and analyze the best reaction

Pesticide Biotransformation and Disposition

Pesticide Biotransformation and Disposition PDF Author: Ernest Hodgson
Publisher: Academic Press
ISBN: 0123854822
Category : Medical
Languages : en
Pages : 236

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Book Description
Biotransformation of Pesticides is an updated, "one-stop" resource for academic, industry and regulatory scientists involved in research and regulatory activities related to pesticide biotransformation and human health. This book provides an in depth look at how pesticides are biotransformed, which is essential to understanding exposure, dose, toxicity and health risks. This essential reference contains the biotransformation of pesticides from uptake to excretion, including toxicokinetics and emphasizes metabolism in non-target species, including experimental animals and humans. - Includes four new chapters and expanded material on pesticide biotransformation and disposition, an active area of pesticide toxicology that is becoming increasingly important for human health risk assessment - Offers a practical and portable guide covering the most up-to-date research results on metabolic transformations of pesticides - Provides scientists and regulatory researchers with the information they need to conduct accurate risk assessments and make informed decisions on which exposures to study further in human populations

Gas Chromatography and Mass Spectrometry: A Practical Guide

Gas Chromatography and Mass Spectrometry: A Practical Guide PDF Author: O. David Sparkman
Publisher: Academic Press
ISBN: 0080920152
Category : Science
Languages : en
Pages : 633

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Book Description
The second edition of Gas Chromatography and Mass Spectrometry: A Practical Guide follows the highly successful first edition by F.G. Kitson, B.S. Larsen, and C.N. McEwen (1996), which was designed as an indispensible resource for GC/MS practitioners regardless of whether they are a novice or well experienced. The Fundamentals section has been extensively reworked from the original edition to give more depth of an understanding of the techniques and science involved with GC/MS. Even with this expansion, the original brevity and simple didactic style has been retained. Information on chromatographic peak deconvolution has been added along with a more in-depth understanding of the use of mass spectral databases in the identification of unknowns. Since the last edition, a number of advances in GC inlet systems and sample introduction techniques have occurred, and they are included in the new edition. Other updates include a discussion on fast GC and options for combining GC detectors with mass spectrometry. The section regarding GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types has the same number of compound types as the original edition, but the information in each section has been expanded to not only explain some of the spectra but to also explain why certain fragmentations take place. The number of Appendices has been increased from 12 to 17. The Appendix on Atomic Masses and Isotope Abundances has been expanded to provide tools to aid in determination of elemental composition from isotope peak intensity ratios. An appendix with examples on "Steps to follow in the determination of elemental compositions based on isotope peak intensities" has been added. Appendices on whether to use GC/MS or LC/MS, third-party software for use in data analysis, list of information required in reporting GC/MS data, X+1 and X+2 peak relative intensities based on the number of atoms of carbon in an ion, and list of available EI mass spectral databases have been added. Others such as the ones on derivatization, isotope peak patterns for ions with Cl and/or Br, terms used in GC and in mass spectrometry, and tips on setting up, maintaining and troubleshooting a GC/MS system have all been expanded and updated. - Covers the practical instruction necessary for successful operation of GC/MS equipment - Reviews the latest advances in instrumentation, ionization methods, and quantitation - Includes troubleshooting techniques and a variety of additional information useful for the GC/MS practitioner - A true benchtop reference - A guide to a basic understanding of the components of a Gas Chromatograph-Mass Spectrometer (GC-MS) - Quick References to data interpretation - Ready source for information on new analyses

Toxicological Profile for Diazinon

Toxicological Profile for Diazinon PDF Author:
Publisher:
ISBN:
Category : Diazinon
Languages : en
Pages : 204

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Book Description


Handbook of Veterinary Neurology - E-Book

Handbook of Veterinary Neurology - E-Book PDF Author: Michael D. Lorenz
Publisher: Elsevier Health Sciences
ISBN: 1437706525
Category : Medical
Languages : en
Pages : 562

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Book Description
Handbook of Veterinary Neurology provides quick access to vital information on neurologic conditions in a wide range of species, including canine, feline, bovine, caprine, equine, ovine, and porcine. A problem-oriented approach makes it easy to diagnose and treat neurologic problems in small and large animals. The coverage of disorders by problem, not by established disease diagnosis, emulates how animals present to the veterinary hospital and simplifies the formulation of a correct diagnosis. Within each chapter, discussions of neurologic disease include a review of the localization criteria and the diseases that can cause that problem, plus treatment and surgical techniques. Lead author Michael D. Lorenz brings decades of experience to neurologic assessment, using a diagnostic approach that requires minimal knowledge of neuroanatomy. - A problem-based approach is organized by presenting sign rather than by condition, guiding you to logical conclusions regarding diagnosis and treatment. - Algorithms diagram the logic necessary to localize lesions and to formulate diagnostic plans. - Coverage of current diagnostic techniques includes the use of diagnostic tools, such as radiology, spinal fluid analysis, electrodiagnosis, and MR imaging. - Case histories in each chapter present a problem and the results of the neurologic examination, then ask you to solve the problem by localizing the lesion, listing probable causes, and making a diagnostic plan. Answers are provided at the back of the book. - A consistent format for each case history includes signalment, history, physical examination findings, and neurologic examination. - A comprehensive appendix describes species and breeds that have a congenital predisposition for particular neurologic diseases. - Extensive references make it easy to pursue in-depth research of more advanced topics. - A companion website includes 20 narrated video clips with accompanying PowerPoint slides that correlate to the case histories in the book, covering neurologic assessment and clinical problems such as paresis of one limb, tetraparesis, stupor, seizures, ataxia of the head and limbs, and cranial nerve disorders. - Two new co-authors, Jean Coates and Marc Kent, board-certified in neurology, enhance the credibility of this edition. - A full-color design and numerous illustrations include enhanced images of neuroanatomy and pathology.