Diagnostic Techniques in Hematological Malignancies PDF Download
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Author: Wendy N. Erber
Publisher: Cambridge University Press
ISBN: 1139491733
Category : Medical
Languages : en
Pages : 349
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Book Description
The diagnosis and monitoring of hematological malignancies is complex and requires a systematic approach. Morphology, cell phenotyping, cytogenetics and molecular genetics are essential, and the results must be integrated. Diagnostic Techniques in Hematological Malignancies details the principles and applications of each of these test types in the diagnosis of hematological malignancies in blood and bone marrow. The first section describes the test modalities – including methodological principles, data interpretation and limitations – and is illustrated by clinical examples. The second section focuses on the clinical entities, detailing the most appropriate tests for diagnosis, staging and monitoring of different hematological malignancies and includes test utilization to identify prognostic markers and potential therapeutic targets. With contributions from multiple international experts, this illustrated book is an essential resource for qualified and trainee hematologists, oncologists, and pathologists. It's a practical and useful guide, providing a rational and structured approach to the laboratory assessment of hematological malignancies.
Author: Wendy N. Erber
Publisher: Cambridge University Press
ISBN: 1139491733
Category : Medical
Languages : en
Pages : 349
Get Book Here
Book Description
The diagnosis and monitoring of hematological malignancies is complex and requires a systematic approach. Morphology, cell phenotyping, cytogenetics and molecular genetics are essential, and the results must be integrated. Diagnostic Techniques in Hematological Malignancies details the principles and applications of each of these test types in the diagnosis of hematological malignancies in blood and bone marrow. The first section describes the test modalities – including methodological principles, data interpretation and limitations – and is illustrated by clinical examples. The second section focuses on the clinical entities, detailing the most appropriate tests for diagnosis, staging and monitoring of different hematological malignancies and includes test utilization to identify prognostic markers and potential therapeutic targets. With contributions from multiple international experts, this illustrated book is an essential resource for qualified and trainee hematologists, oncologists, and pathologists. It's a practical and useful guide, providing a rational and structured approach to the laboratory assessment of hematological malignancies.
Author: Michal Witt
Publisher: Springer Science & Business Media
ISBN: 3642294677
Category : Science
Languages : en
Pages : 468
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Book Description
This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Author: Anna Porwit
Publisher: Cambridge University Press
ISBN: 1108548830
Category : Medical
Languages : en
Pages : 248
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Book Description
Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.
Author: Ali Guermazi
Publisher: Springer Science & Business Media
ISBN: 364218832X
Category : Medical
Languages : en
Pages : 585
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Book Description
One of the first book’s to deal specifically with imaging of the entire spectrum of hematological malignancies. The use of the latest imaging modalities is well described, and an important aspect of the book is the role of imaging techniques in differentiating between manifestations of the underlying disease and complications of treatment. Each of the 28 chapters is written by an internationally recognized expert, making this book the most current and complete treatment of this subject available. Includes many high-quality radiological and histological illustrations. It should be of great interest to radiologists and hematologists.
Author: Wojciech Gorczyca
Publisher: CRC Press
ISBN: 9780415420099
Category : Medical
Languages : en
Pages : 0
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Book Description
Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially polymerase chain reaction (PCR), play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis, as well as predict prognosis, response to treatment and disease progression. Chromosomal and molecular abnormalities provide the most reliable criteria for classification of hematopoietic tumors and often comprise the basis for targeted therapy. Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies, provides a review of chromosomal and molecular changes in hematologic malignancies and correlates the karyotypic and genetic abnormalities with morphology, immunophenotype and clinical data. With over 180 figures and diagnostic algorithms, this text is essential reading for all pathologists, hematopathologists, hematologic oncologists, cytogenetists, cytogenetic technologists and cell biologists.
Author: Georg Maschmeyer
Publisher: Springer
ISBN: 3662440008
Category : Medical
Languages : en
Pages : 328
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Book Description
Infections are among the most frequent complications in patients with hematological malignancies and in those undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation. A profound knowledge on the epidemiology, diagnostic approaches, treatment modalities and prophylactic strategies is essential for the clinical management of these complications in patients who are often severely immunocompromised owing to their underlying diseases and in particular, the intensive myelosuppressive chemo and immunotherapy. This textbook provides a clinically oriented, compact and up-to-date overview on infections in hematology patients and their management. The typical pathogens to be considered in different subgroups of patients are identified and further aspects of the microbiological background are explored. Clinical, imaging, and laboratory-based diagnostic techniques are discussed and therapeutic strategies appropriate to different situations are then presented, with due attention to the pitfalls, toxicities and interactions that can arise during antimicrobial treatment. Strategies to prevent infection are also outlined, encompassing antimicrobial prophylaxis, isolation procedures, hospital hygiene, protective immunization and the use of hematopoietic growth factors.
Author: Drew Provan
Publisher: John Wiley & Sons
ISBN: 1394180470
Category : Medical
Languages : en
Pages : 452
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Book Description
Provides a core knowledgebase for those with minimal exposure to hematologic molecular biology, fully revised and updated Molecular Hematology brings together the most up-to-date and reliable information on the molecular basis of major hematologic diseases. Edited and authored by leading experts in the field, this volume demonstrates the clinical relevance of molecular biology in the diagnosis and treatment of blood disorders. Concise, accessible chapters address key topics in modern hematology, such as lymphoma genetics, molecular coagulation, thrombophilia, pharmacogenomics, platelet disorders, hemophilia, anemia, and multiple myeloma. Chapters introduce and summarize specific hematologic diseases, explore the pathogenesis of the disorder, highlight new and emerging molecular strategies, and more. Now in its fifth edition, Molecular Hematology is fully revised to incorporate contemporary hematology research and practice. Entirely new chapters cover topics such as CAR-T cell technology, COVID, cancer cell biology, gene therapy and gene editing in clinical practice, as well as the impact of molecular research on the diagnosis and treatment of various malignant hematologic diseases. This edition includes updated suggested readings and a wealth of new full-color charts, graphs, and illustrations throughout. Covers the molecular biology of different blood diseases, their pathogeneses, and current molecular research and therapies Illustrates the impact of molecular research on hematologic investigations and therapeutics Discusses how progress in basic science and therapeutics has improved the diagnosis and care of patients with various hematologic disorders Surveys recent developments in cancer-cell biology, with an emphasis on leukemia and lymphoma Includes access to a companion Digital Edition providing search across the book, downloadable illustrations, and notation tools Molecular Hematology is a must-have resource for established and trainee clinicians, clinical scientists and researchers, medical students, and upper-level undergraduates in the fields of hematology, oncology, and molecular biology.
Author: David A. Sallman
Publisher: Demos Medical Publishing
ISBN: 9781620700945
Category : Lymphoproliferative disorders
Languages : en
Pages : 0
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Book Description
MDS/MPN With Ring Sideroblasts and Thrombocytosis
Author: Mohamed E. Salama
Publisher: Elsevier Health Sciences
ISBN: 0323567347
Category : Medical
Languages : en
Pages : 415
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Book Description
Ideal as a quick, easy-to-use reference in the laboratory or clinical setting, Atlas of Diagnostic Hematology is an abundantly illustrated guide to the vast range of malignant and non-malignant disorders of the blood. More than 1,200 vibrant, full-color images enable you to identify and compare the unique clinical and histologic features of various blood disorders and confidently reach a diagnosis. Coverage includes photos of actual cases that span the entire range of this complex field, including rare conditions and difficult diagnoses. - Features more than 1,200 images including full-color pathologic and clinical images covering a wide range of hematologic malignant and non-malignant conditions. - Covers a range of disease stages, from the slightest indication where diagnosis can be complicated or missed entirely, to what the average blood or biopsy sample signifying disease may look like, to an advanced stage where disease indications are abundantly clear. - Helps you distinguish between similar and overlapping features and symptoms to arrive at an accurate diagnosis. - Provides up-to-date information on infectious processes in blood and bone marrow, classification system of myeloid neoplasms, and indolent and aggressive mature T and NK-cell lymphomas. - Includes diagnostic algorithms with differential diagnoses for conditions with similar histologic features and clinical symptoms. - Contains the latest WHO classifications for pathologic, genetic, and clinical information.
Author: Dan Jones
Publisher: Springer Science & Business Media
ISBN: 1607613840
Category : Medical
Languages : en
Pages : 636
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Book Description
Fulfilling the void with a Hematopathology book that integrates clinical and experimental studies with diagnostic criteria, Neoplastic Hematopathology: Experimental and Clinical Approaches provides an overview of the discipline of hematopathology that connects the field with recent advances in immunology research and current clinical practice in the treatment of lymphomas and leukemias. Designed for both trainees and specialists in pathology and hematology-oncology, Neoplastic Hematopathology: Experimental and Clinical Approaches has separate sections on laboratory techniques, diagnostic hematopathology, treatment and stem cell transplantation. Expert chapter authors address both myeloid and lymphoid tumors, and provide much needed coverage in transplant biology. A study guide highlights key chapter points, making the text suitable for boards review in hematopathology and hematology-oncology.
