Developmental Biology of Gastrointestinal Hormones PDF Download
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Author: M. Wabitsch
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318059749
Category : Medical
Languages : en
Pages : 200
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Book Description
The gut not only represents the largest endocrine organ of the human body but is also profoundly involved in the control of metabolism through peptide hormones. Therefore, gastrointestinal hormones are acting via autocrine, paracrine, and classical endocrine pathways and regulate e.g. digestion, hunger, and satiety. Furthermore, they are important regulators of body weight, growth, and glucose metabolism, as well as of mood and behavior. Physicians and scientists in the field of pediatric endocrinology and diabetes, as well as in pediatric gastroenterology, require an extensive understanding of the origin of enteroendocrine cells, factors controlling their differentiation, hormone gene expression, secretion, function and, finally, the complex interaction with other organs, especially the central nervous system. In order to meet these needs, experts in the field have written up-to-date, comprehensive, and illustrated reviews presenting the current knowledge in the field of gastrointestinal endocrinology with a pediatric view. Those reviews comprise this latest volume of Endocrine Development.
Author: M. Wabitsch
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318059749
Category : Medical
Languages : en
Pages : 200
Get Book Here
Book Description
The gut not only represents the largest endocrine organ of the human body but is also profoundly involved in the control of metabolism through peptide hormones. Therefore, gastrointestinal hormones are acting via autocrine, paracrine, and classical endocrine pathways and regulate e.g. digestion, hunger, and satiety. Furthermore, they are important regulators of body weight, growth, and glucose metabolism, as well as of mood and behavior. Physicians and scientists in the field of pediatric endocrinology and diabetes, as well as in pediatric gastroenterology, require an extensive understanding of the origin of enteroendocrine cells, factors controlling their differentiation, hormone gene expression, secretion, function and, finally, the complex interaction with other organs, especially the central nervous system. In order to meet these needs, experts in the field have written up-to-date, comprehensive, and illustrated reviews presenting the current knowledge in the field of gastrointestinal endocrinology with a pediatric view. Those reviews comprise this latest volume of Endocrine Development.
Author: Rao N. Jaladanki
Publisher: Biota Publishing
ISBN: 1615047352
Category : Medical
Languages : en
Pages : 150
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Book Description
The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.
Author: Anthony W. Norman
Publisher: Academic Press
ISBN: 1483258106
Category : Science
Languages : en
Pages : 823
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Book Description
Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.
Author: John H. Walsh
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 904
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Book Description
Provides a comprehensive approach to gastrointestinal hormones, for clinicians and scientists who are interested in hormonal regulation of the gastrointestinal tract. The first section discusses general issues related to peptides as messengers, including receptors and signal transduction and control of gene expression. The second section presents the biochemical and physiological features of the gastrointestinal hormones and neuropeptides. The third section integrates these peptides into physiological and pathophysiological regulatory pathways of the gut. Annotation copyright by Book News, Inc., Portland, OR
Author: Samantha Fowler
Publisher:
ISBN: 9781739015503
Category :
Languages : en
Pages : 0
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Book Description
Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Author: Antonino Belfiore
Publisher: Springer
ISBN: 9783319446745
Category : Medical
Languages : en
Pages : 0
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Book Description
This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Author: Debasis Bagchi
Publisher: Academic Press
ISBN: 0123850835
Category : Health & Fitness
Languages : en
Pages : 553
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Book Description
Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions plus both Type I and Type II Diabetes Presents both prevention and treatment options
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309366860
Category : Medical
Languages : en
Pages : 198
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Book Description
On July 9-10, 2014, the Institute of Medicine's Food Forum hosted a public workshop to explore emerging and rapidly developing research on relationships among the brain, the digestive system, and eating behavior. Drawing on expertise from the fields of nutrition and food science, animal and human physiology and behavior, and psychology and psychiatry as well as related fields, the purpose of the workshop was to (1) review current knowledge on the relationship between the brain and eating behavior, explore the interaction between the brain and the digestive system, and consider what is known about the brain's role in eating patterns and consumer choice; (2) evaluate current methods used to determine the impact of food on brain activity and eating behavior; and (3) identify gaps in knowledge and articulate a theoretical framework for future research. Relationships among the Brain, the Digestive System, and Eating Behavior summarizes the presentations and discussion of the workshop.
Author: Shlomo Melmed
Publisher: Springer Science & Business Media
ISBN: 1592598293
Category : Medical
Languages : en
Pages : 424
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Book Description
Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, this new edition succinctly summarizes in 450 pages the latest findings on hormone secretion and hormone action, as well as all the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in man and the lower species, and the mechanisms subserving hormone secretion.
Author: Webb
Publisher: Oxford University Press
ISBN: 0198855435
Category : Medical
Languages : en
Pages : 1961
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Book Description
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
