Development of Matrix-assisted Laser Desorption Ionization Mass Spectrometry for Biopolymer Analysis PDF Download
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Author:
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Category :
Languages : en
Pages :
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Author:
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ISBN:
Category :
Languages : en
Pages :
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Book Description
![Development of Matrix-assisted Laser Desorption Ionization Mass Spectrometry for Biopolymer Analysis [microform] PDF](https://books.google.com/books/content/images/frontcover/R40SNQEACAAJ?fife=w80-h100)
Author: Yuqin Dai
Publisher: National Library of Canada = Bibliothèque nationale du Canada
ISBN: 9780612395190
Category :
Languages : en
Pages : 332
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Author: Sajid Bashir
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Category :
Languages : en
Pages :
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Author: Marc Roger Chevrier
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Category :
Languages : en
Pages : 374
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Author:
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Category :
Languages : en
Pages : 135
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This thesis presents efforts to improve the methodology of matrix-assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) as a method for analysis of metabolites from plant tissue samples. The first chapter consists of a general introduction to the technique of MALDI-MSI, and the sixth and final chapter provides a brief summary and an outlook on future work.
Author: Jonathon Kevin Gooden
Publisher:
ISBN:
Category :
Languages : en
Pages : 424
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Author: Haixing Wang
Publisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 175
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Author: Moon-Ju Kim
Publisher: Springer Nature
ISBN: 981996878X
Category : Science
Languages : en
Pages : 107
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This book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is currently facing and for enhancing LDI efficiency. It presents a variety of cutting-edge nanophotonic structures to satisfy the mass-analytical needs of sensitivity, reproducibility, and quantification. As opposed to the commercialized, conventional organic matrix used in MALDI-MS, these nanostructures are validated to be highly effective in detecting small metabolites and drugs, highlighting their considerable potential in the mass spectrometry field. It also systematically elucidates fundamental LDI processes in terms of the photo-thermal, electronic, and structural characteristics of nanophotonic structures, offering mechanistic knowledge of LDI-MS. Even though LDI-MS performance is heavily influenced by a number of nanostructure parameters, relatively little is known about the LDI processes associated with those characteristics. An in-depth understanding of nanostructure characteristics and LDI mechanisms thus paves the way for more effective, rational design and development of nanostructures with improved LDI capabilities. Further, with a focus on multiple cascades in nanostructure functions in response to laser pulse stimuli, this book provides detailed, step-by-step procedures to design and construct a nanophotonic, LDI-active platform, which may serve as a roadmap for graduate students in the field of mass spectrometry. Readers, including graduate students, researchers, and experts working in the related areas of mass spectrometry, nanophotonics, and material science and material engineering, will find a wealth of useful information in this book.
Author: Hassan Rashidzadeh
Publisher:
ISBN:
Category : Electron-stimulated desorption
Languages : en
Pages : 230
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Author: Rainer Cramer
Publisher: Springer
ISBN: 3319048198
Category : Science
Languages : en
Pages : 287
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This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics
