Author: Francis Nicholas Marzulli
Publisher: CRC Press
ISBN: 9781560320555
Category : Medical
Languages : en
Pages : 1960
Book Description
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.
DERMATOTOXICOLOGY 4ED
Author: Francis Nicholas Marzulli
Publisher: CRC Press
ISBN: 9781560320555
Category : Medical
Languages : en
Pages : 1960
Book Description
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.
Publisher: CRC Press
ISBN: 9781560320555
Category : Medical
Languages : en
Pages : 1960
Book Description
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.
Dermatotoxicology
Author: Hongbo Zhai
Publisher: CRC Press
ISBN: 0203426274
Category : Medical
Languages : en
Pages : 1232
Book Description
For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, De
Publisher: CRC Press
ISBN: 0203426274
Category : Medical
Languages : en
Pages : 1232
Book Description
For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, De
Dermatotoxicology
Author: Klaus Peter Wilhelm
Publisher: CRC Press
ISBN: 142000977X
Category : Medical
Languages : en
Pages : 1044
Book Description
Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated
Publisher: CRC Press
ISBN: 142000977X
Category : Medical
Languages : en
Pages : 1044
Book Description
Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated
Volunteers in Research and Testing
Author: Bryony Close
Publisher: CRC Press
ISBN: 1482295245
Category : Medical
Languages : en
Pages : 194
Book Description
This text discusses the use of volunteers, either healthy or undergoing treatment, in the research and testing of medicinal and non-medicinal products. The extent to which the improved use of such volunteers could reduce the need for animal tests is
Publisher: CRC Press
ISBN: 1482295245
Category : Medical
Languages : en
Pages : 194
Book Description
This text discusses the use of volunteers, either healthy or undergoing treatment, in the research and testing of medicinal and non-medicinal products. The extent to which the improved use of such volunteers could reduce the need for animal tests is
Exposure to Contaminants in Drinking Water
Author: Stephen S Olin
Publisher: CRC Press
ISBN: 1000141144
Category : Technology & Engineering
Languages : en
Pages : 254
Book Description
Exposure to Contaminants in Drinking Water: Estimating Uptake through the Skin and by Inhalation examines the current state of science in this field by identifying and reviewing the available information resources; evaluating various models and approaches; and demonstrating the feasibility of developing estimates of the distribution of absorbed doses of contaminants in drinking water through contact with the skin and by inhalation. This book, the product of a fifteen-member expert working group convened by the Risk Science Institute of the International Life Sciences Institute under a cooperative agreement with the U.S. Environmental Protection Agency's Office of Water, includes contributions from experts in exposure modeling and measurement; water chemistry; time-activity patterns; dermal and respiratory uptake; and the use of probability distributions in characterizing exposures.
Publisher: CRC Press
ISBN: 1000141144
Category : Technology & Engineering
Languages : en
Pages : 254
Book Description
Exposure to Contaminants in Drinking Water: Estimating Uptake through the Skin and by Inhalation examines the current state of science in this field by identifying and reviewing the available information resources; evaluating various models and approaches; and demonstrating the feasibility of developing estimates of the distribution of absorbed doses of contaminants in drinking water through contact with the skin and by inhalation. This book, the product of a fifteen-member expert working group convened by the Risk Science Institute of the International Life Sciences Institute under a cooperative agreement with the U.S. Environmental Protection Agency's Office of Water, includes contributions from experts in exposure modeling and measurement; water chemistry; time-activity patterns; dermal and respiratory uptake; and the use of probability distributions in characterizing exposures.
Veterinary and Human Toxicology
Author:
Publisher:
ISBN:
Category : Toxicology
Languages : en
Pages : 416
Book Description
Publisher:
ISBN:
Category : Toxicology
Languages : en
Pages : 416
Book Description
CRC Handbook of Toxicology
Author: Michael J. Derelanko
Publisher: CRC Press
ISBN:
Category : Medical
Languages : en
Pages : 990
Book Description
This text contains practical reference information for toxicologists in the chemical and pharmaceutical industries, contract laboratories and pharmaceutical regulation laboratories.
Publisher: CRC Press
ISBN:
Category : Medical
Languages : en
Pages : 990
Book Description
This text contains practical reference information for toxicologists in the chemical and pharmaceutical industries, contract laboratories and pharmaceutical regulation laboratories.
Cosmetic Dermatology
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 334
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 334
Book Description
Computational Toxicology
Author: Sean Ekins
Publisher: John Wiley & Sons
ISBN: 0470145889
Category : Science
Languages : en
Pages : 855
Book Description
A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins. It covers the in vitro models used, newer technologies, and regulatory aspects. The book offers a complete systems perspective to risk assessment prediction, discussing experimental and computational approaches in detail, with: * An introduction to toxicology methods and an explanation of computational methods * In-depth reviews of QSAR methods applied to enzymes, transporters, nuclear receptors, and ion channels * Sections on applying computers to toxicology assessment in the pharmaceutical industry and in the environmental arena * Chapters written by leading international experts * Figures that illustrate computational models and references for further information This is a key resource for toxicologists and scientists in the pharmaceutical industry and environmental sciences as well as researchers involved in ADMET, drug discovery, and technology and software development.
Publisher: John Wiley & Sons
ISBN: 0470145889
Category : Science
Languages : en
Pages : 855
Book Description
A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins. It covers the in vitro models used, newer technologies, and regulatory aspects. The book offers a complete systems perspective to risk assessment prediction, discussing experimental and computational approaches in detail, with: * An introduction to toxicology methods and an explanation of computational methods * In-depth reviews of QSAR methods applied to enzymes, transporters, nuclear receptors, and ion channels * Sections on applying computers to toxicology assessment in the pharmaceutical industry and in the environmental arena * Chapters written by leading international experts * Figures that illustrate computational models and references for further information This is a key resource for toxicologists and scientists in the pharmaceutical industry and environmental sciences as well as researchers involved in ADMET, drug discovery, and technology and software development.
Skin Reactions to Drugs
Author: Kirsti Kauppinen
Publisher: CRC Press
ISBN: 1000142345
Category : Health & Fitness
Languages : en
Pages : 206
Book Description
Skin reactions to drugs are a ubiquitous problem-the most commonly observed drug sensitivity observed in a wide range of specialties. Skin Reactions to Drugs emphasizes the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions. It discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world. In this textbook, 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers, Skin Reactions to Drugs represents the platinum standard of research conducted on the causation of certain adverse reactions of skin.
Publisher: CRC Press
ISBN: 1000142345
Category : Health & Fitness
Languages : en
Pages : 206
Book Description
Skin reactions to drugs are a ubiquitous problem-the most commonly observed drug sensitivity observed in a wide range of specialties. Skin Reactions to Drugs emphasizes the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions. It discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world. In this textbook, 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers, Skin Reactions to Drugs represents the platinum standard of research conducted on the causation of certain adverse reactions of skin.