Frontiers in Clinical Drug Research – Dementia: Volume 2

Frontiers in Clinical Drug Research – Dementia: Volume 2 PDF Author: José Juan Antonio Ibarra Arias
Publisher: Bentham Science Publishers
ISBN: 9815039482
Category : Science
Languages : en
Pages : 277

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Book Description
Among neurodegenerative diseases, those that lead to a state of dementia are the aim of several investigations. Dementia is a chronic disease the prevalence of which is increasing worldwide. The number of dementia patients in the world is approximately 50 million, and it is estimated that the number of patients will reach 131.5 million by 2050. This increase will be accompanied by a significant increase in medical expenditures and other expenses, especially for elderly patients. Therefore, the maintenance cost of dementia in the future is expected to be quite high. For this reason, several investigations aim, firstly, to describe the key mechanisms involved in the origin of dementia and, secondly, to establish preventive and therapeutic strategies in order to understand and mitigate this debilitating pathology. This volume of Frontiers in Clinical Drug Research - Dementia explores the current comorbidities that cause cognitive impairment and the current management alternatives for clinical cases of dementia. The reviews contributed in these volume will provide readers with a current perspective on the subject. The topics covered in this volume include: - Comorbidities inducing mild cognitive impairment - an evaluation of the risk caused by some pathological conditions - Tau-targeted therapy in Alzheimer's disease - history and current state - Emerging nanotherapeutic strategies in Alzheimer's disease - Implication of dehydroepiandrosterone on dementia related to oxidative stress - Polyphenol compounds as potential therapeutic agents in Alzheimer’s disease The volume is a timely update on dementia treatment for clinical physicians, neurologists, gerontologists, pharmaceutical and medicinal chemistry researchers, and physiologists.

Type 2 Diabetes and Dementia

Type 2 Diabetes and Dementia PDF Author: Velandai Srikanth
Publisher: Academic Press
ISBN: 0128096942
Category : Medical
Languages : en
Pages : 322

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Book Description
Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. - Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics - Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology - Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications

Frontiers in Clinical Drug Research – Dementia: Volume 2

Frontiers in Clinical Drug Research – Dementia: Volume 2 PDF Author: José Juan Antonio Ibarra Arias
Publisher: Bentham Science Publishers
ISBN: 9815039482
Category : Science
Languages : en
Pages : 277

Get Book Here

Book Description
Among neurodegenerative diseases, those that lead to a state of dementia are the aim of several investigations. Dementia is a chronic disease the prevalence of which is increasing worldwide. The number of dementia patients in the world is approximately 50 million, and it is estimated that the number of patients will reach 131.5 million by 2050. This increase will be accompanied by a significant increase in medical expenditures and other expenses, especially for elderly patients. Therefore, the maintenance cost of dementia in the future is expected to be quite high. For this reason, several investigations aim, firstly, to describe the key mechanisms involved in the origin of dementia and, secondly, to establish preventive and therapeutic strategies in order to understand and mitigate this debilitating pathology. This volume of Frontiers in Clinical Drug Research - Dementia explores the current comorbidities that cause cognitive impairment and the current management alternatives for clinical cases of dementia. The reviews contributed in these volume will provide readers with a current perspective on the subject. The topics covered in this volume include: - Comorbidities inducing mild cognitive impairment - an evaluation of the risk caused by some pathological conditions - Tau-targeted therapy in Alzheimer's disease - history and current state - Emerging nanotherapeutic strategies in Alzheimer's disease - Implication of dehydroepiandrosterone on dementia related to oxidative stress - Polyphenol compounds as potential therapeutic agents in Alzheimer’s disease The volume is a timely update on dementia treatment for clinical physicians, neurologists, gerontologists, pharmaceutical and medicinal chemistry researchers, and physiologists.

Future Directions for the Demography of Aging

Future Directions for the Demography of Aging PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309474108
Category : Social Science
Languages : en
Pages : 409

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Book Description
Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.

Preventing Dementia?

Preventing Dementia? PDF Author: Annette Leibing
Publisher: Berghahn Books
ISBN: 1789209102
Category : Medical
Languages : en
Pages : 268

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Book Description
The conceptualization of dementia has changed dramatically in recent years with the claim that, through early detection and by controlling several risk factors, a prevention of dementia is possible. Although encouraging and providing hope against this feared condition, this claim is open to scrutiny. This volume looks at how this new conceptualization ignores many of the factors which influence a dementia sufferers’ prognosis, including their history with education, food and exercise as well as their living in different epistemic cultures. The central aim is to question the concept of prevention and analyze its impact on aging people and aging societies.

Chronic Disease in the Twentieth Century

Chronic Disease in the Twentieth Century PDF Author: George Weisz
Publisher: JHU Press
ISBN: 1421413027
Category : Law
Languages : en
Pages : 326

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Book Description
Chronic Disease in the Twentieth Century challenges the conventional wisdom that the concept of chronic disease emerged because medicine's ability to cure infectious disease led to changing patterns of disease. Instead, it suggests, the concept was constructed and has evolved to serve a variety of political and social purposes. How and why the concept developed differently in the United States, an United Kingdom, and France are central concerns of this work. While an international consensus now exists, the different paths taken by these three countries continue to exert profound influence. This book seeks to explain why, among the innumerable problems faced by societies, some problems in some places become viewed as critical public issues that shape health policy. -- from back cover.

Neurology in Clinical Practice

Neurology in Clinical Practice PDF Author: Walter George Bradley
Publisher:
ISBN: 9780750674690
Category : Diagnosis
Languages : en
Pages : 1672

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Book Description
New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.

Chronic Medical Disease and Cognitive Aging

Chronic Medical Disease and Cognitive Aging PDF Author: Kristine Yaffe
Publisher: Oxford University Press
ISBN: 0199793557
Category : Family & Relationships
Languages : en
Pages : 317

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Book Description
This book explores the important and often overlooked connection between how chronic medical diseases of the body can affect the brain. Experts within the field discuss current research, potential biological mechanisms, and possible interventions or treatments aimed at improving cognitive health for a variety of medical diseases.

Design for People Living with Dementia

Design for People Living with Dementia PDF Author: Emmanuel Tsekleves
Publisher: Routledge
ISBN: 0429808976
Category : Health & Fitness
Languages : en
Pages : 157

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Book Description
There were an estimated 50 million people worldwide living with dementia in 2017 and this number will almost double every 20 years, reaching 82 million in 2030. Design has significant potential to contribute to managing this global concern. This book is the first to synthesise the considerable research and projects in dementia and design. Design interactions is a new way of considering how we can improve the relationship between people, products, places and services and of course technology trends, such as the ‘internet of things’, offer great opportunities in providing new ways to connect people with services and products that can contribute to healthier lifestyles and mechanisms to support people with acute and chronic conditions. In light of this, the book explores the contribution and future potential of design for dementia through the lens of design interactions, such as people, contexts, material and things. Design for People Living with Dementia is a guide to this innovative and cutting-edge field in healthcare. This book is essential reading for healthcare managers working to provide products, services and care to people with dementia, as well as design researchers and students. .

Living Well at the End of Life

Living Well at the End of Life PDF Author: Joanne Lynn
Publisher: RAND Corporation
ISBN:
Category : Medical
Languages : en
Pages : 32

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Book Description
Self-care deficits and a slowly dwindling course to death, which usually results from frailty or dementia. Effective and reliable care for persons coming to the end of life will require changes in the organization and financing of care to match these trajectories, as well as compassionate and skillful clinicians. (Available from the publisher or libraries holding the journal.).

Living Well with Chronic Illness

Living Well with Chronic Illness PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309221277
Category : Medical
Languages : en
Pages : 350

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Book Description
In the United States, chronic diseases currently account for 70 percent of all deaths, and close to 48 million Americans report a disability related to a chronic condition. Today, about one in four Americans have multiple diseases and the prevalence and burden of chronic disease in the elderly and racial/ethnic minorities are notably disproportionate. Chronic disease has now emerged as a major public health problem and it threatens not only population health, but our social and economic welfare. Living Well with Chronic Disease identifies the population-based public health actions that can help reduce disability and improve functioning and quality of life among individuals who are at risk of developing a chronic disease and those with one or more diseases. The book recommends that all major federally funded programmatic and research initiatives in health include an evaluation on health-related quality of life and functional status. Also, the book recommends increasing support for implementation research on how to disseminate effective longterm lifestyle interventions in community-based settings that improve living well with chronic disease. Living Well with Chronic Disease uses three frameworks and considers diseases such as heart disease and stroke, diabetes, depression, and respiratory problems. The book's recommendations will inform policy makers concerned with health reform in public- and private-sectors and also managers of communitybased and public-health intervention programs, private and public research funders, and patients living with one or more chronic conditions.