Délais des traitements adjuvants du cancer du sein et impact sur le pronostic des patientes PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Délais des traitements adjuvants du cancer du sein et impact sur le pronostic des patientes PDF full book. Access full book title Délais des traitements adjuvants du cancer du sein et impact sur le pronostic des patientes by Margaux Lesage. Download full books in PDF and EPUB format.
Author: Margaux Lesage
Publisher:
ISBN:
Category :
Languages : fr
Pages : 84
Get Book Here
Book Description
Introduction : Le cancer du sein est le premier cancer féminin en France. Parallélement à l'augmentation constante de son incidence, on assiste à une augmentation des délais pour l'accès aux soins. La maîtrise de ces délais est donc devenue un des objectifs phares de notre Plan Cancer 2014-2019. Objectif: Evaluer les délais d'accès aux traitements adjuvants du cancer du sein et étudier leur impact sur le pronostic des patientes. Matériels et Méthodes : Etude descriptive rétrospective unicentrique au Centre Hospitalo-Universitaire de Tours entre le 1er janvier 2009 et le 31 décembre 2013 . L'ensemble des patientes opérées pour un cancer du sein sur cette période ont été incluses, soit 2203 patientes. Les délais d'accès aux traitements adjuvants (hors hormonothérapie) ont été relevés : délai chirurgie-chimiothérapie et délai chirurgie-radiothérapie . La survie globale et la survie sans rechute (absence de récidive loco-régionale ou métastatique à distance) ont été utlisées pour étudier l'impact sur le pronostic. Résultats : Les délais d'accès aux traitements adjuvants de 1855 patientes ont été analysés. Toutes présentaient un cancer de type infiltrant. Celles-ci ont été réparties en 3 groupes pour les besoins de l'étude: patientes avec radiothérapie adjuvante seule, avec chimiothérapie néo-adjuvante, et avec chimiothérapie adjuvante. Le délai d'accès à la radiothérapie post-opératoire était en moyenne de 64 jours. En cas de chirurgie mammaire conservatrice, un délai d'accès à la radiothérapie de 60 jours a été identifié comme facteur pronostique impactant la survie globale et la survie sans rechute. La réalisation d'une radiothérapie à plus de 240 jours de la date de la première séance de chimiothérapie néo-adjuvante était un facteur pronostique indépendant. Enfin, le délai moyen chirurgie-chimiothérapie adjuvante était de 56 jours, et aucun lien entre ce délai et la survie des patientes n'a été retrouvé. Conclusion : Le respect des délais d'accès aux traitements adjuvants du cancer du sein impacte la survie des patientes, notamment en cas de chirurgie mammaire conservatrice.
Author: Margaux Lesage
Publisher:
ISBN:
Category :
Languages : fr
Pages : 84
Get Book Here
Book Description
Introduction : Le cancer du sein est le premier cancer féminin en France. Parallélement à l'augmentation constante de son incidence, on assiste à une augmentation des délais pour l'accès aux soins. La maîtrise de ces délais est donc devenue un des objectifs phares de notre Plan Cancer 2014-2019. Objectif: Evaluer les délais d'accès aux traitements adjuvants du cancer du sein et étudier leur impact sur le pronostic des patientes. Matériels et Méthodes : Etude descriptive rétrospective unicentrique au Centre Hospitalo-Universitaire de Tours entre le 1er janvier 2009 et le 31 décembre 2013 . L'ensemble des patientes opérées pour un cancer du sein sur cette période ont été incluses, soit 2203 patientes. Les délais d'accès aux traitements adjuvants (hors hormonothérapie) ont été relevés : délai chirurgie-chimiothérapie et délai chirurgie-radiothérapie . La survie globale et la survie sans rechute (absence de récidive loco-régionale ou métastatique à distance) ont été utlisées pour étudier l'impact sur le pronostic. Résultats : Les délais d'accès aux traitements adjuvants de 1855 patientes ont été analysés. Toutes présentaient un cancer de type infiltrant. Celles-ci ont été réparties en 3 groupes pour les besoins de l'étude: patientes avec radiothérapie adjuvante seule, avec chimiothérapie néo-adjuvante, et avec chimiothérapie adjuvante. Le délai d'accès à la radiothérapie post-opératoire était en moyenne de 64 jours. En cas de chirurgie mammaire conservatrice, un délai d'accès à la radiothérapie de 60 jours a été identifié comme facteur pronostique impactant la survie globale et la survie sans rechute. La réalisation d'une radiothérapie à plus de 240 jours de la date de la première séance de chimiothérapie néo-adjuvante était un facteur pronostique indépendant. Enfin, le délai moyen chirurgie-chimiothérapie adjuvante était de 56 jours, et aucun lien entre ce délai et la survie des patientes n'a été retrouvé. Conclusion : Le respect des délais d'accès aux traitements adjuvants du cancer du sein impacte la survie des patientes, notamment en cas de chirurgie mammaire conservatrice.
Author: Monica Castiglione
Publisher: Springer Science & Business Media
ISBN: 0387751157
Category : Medical
Languages : en
Pages : 483
Get Book Here
Book Description
Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Author: Oreste Gentilini
Publisher: Springer Nature
ISBN: 3030247627
Category : Medical
Languages : en
Pages : 218
Get Book Here
Book Description
This contributed book covers all aspects concerning the clinical scenario of breast cancer in young women, providing physicians with the latest information on the topic. Young women are a special subset of patients whose care requires dedicated expertise. The book, written and edited by internationally recognized experts who have been directly involved in the international consensus guidelines for breast cancer in young women, pays particular attention to how the disease and its planned treatment can be effectively communicated to young patients. Highly informative and carefully structured, it provides both theoretical and practice-oriented insight for practitioners and professionals involved in the different phases of treatment, from diagnosis to intervention, to follow-up – without neglecting the important role played by prevention.
Author: Konstantinos N. Chatzigeorgiou
Publisher: Nova Science Publishers
ISBN:
Category : Metastasis
Languages : en
Pages : 234
Get Book Here
Book Description
Ovarian cancer is the most common cause of death among all gynecological neoplasms. Ovarian epithelial cancer represents approximately 90% of all ovarian malignant tumours. The most usual pattern of spread and probably the earliest kind of metastasis of ovarian cancer is intraperitoneal spread, caused by apoptosis of viable cancer cells, even in cases where the ovarian surface has no visible rupture. Approximately 70% to 75% of all ovarian cancers are being diagnosed with peritoneal carcinomatosis and ascites in advanced stages III and IV. Peritoneal carcinomatosis from ovarian cancer may occur either concomitantly with the primary tumour or as a recurrence pattern of spread. Standard treatment consists of surgical debulking and postoperative systemic chemotherapy. Response rates to first-line chemotherapy with platinum/taxane combinations are high, about 70-80%, but the vast majority of patients will relapse. Peritoneal seeding is a major cause of surgical treatment failure among those patients, even after optimal debulking. However, progressing ovarian cancer tends to remain within the peritoneal cavity or, better-expressed, ovarian cancer is a cancer of the peritoneum. The administration of cytotoxic agents directly into the peritoneal cavity as treatment for malignancy was initially evaluated more than 40 years ago. Over the past two decades regional therapy of ovarian cancer has evolved from just an interesting pharmacokinetic concept into a viable management option for women with advanced disease. Several authors, and among them some of the world's leading experts on this field present the current knowledge and their experience on peritoneal carcinomatosis from ovarian cancer.
Author: Gw Sledge
Publisher: Clinical Pub
ISBN: 9781846920660
Category : Breast
Languages : en
Pages : 0
Get Book Here
Book Description
This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.
Author: Leszek Szablewski
Publisher: BoD – Books on Demand
ISBN: 178985525X
Category : Medical
Languages : en
Pages : 140
Get Book Here
Book Description
The main source of energy for the body is glucose. Its low blood concentrations can cause seizures, loss of consciousness and death. Long lasting high glucose levels can cause blindness, renal failure, cardiac and peripheral vascular disease, and neuropathy. Blood glucose concentrations need to be maintained within narrow limits. The process of maintaining blood glucose at a steady state is called glucose homeostasis. This is achieved through a balance of the rate of consumption of dietary carbohydrates, utilization of glucose by peripheral tissues, and the loss of glucose through the kidney tubule. The liver and kidney also play a role in glucose homeostasis. This book aims to provide an overview of blood glucose levels in health and diseases.
Author: Irving M. Ariel
Publisher: McGraw-Hill Companies
ISBN:
Category : Health & Fitness
Languages : en
Pages : 592
Get Book Here
Book Description
Author: J. Zander
Publisher: Springer Science & Business Media
ISBN: 3642701922
Category : Medical
Languages : en
Pages : 384
Get Book Here
Book Description
March 23 and 24, 1983 saw the fIrst international symposium held under the auspices of the Wilhelm Vaillant Foundation for the Advancement of Pro phylactic Medicine in the I. Frauenklinik der Ludwig Maximilians Univer sitiit Miinchen. This symposium was concerned with Advances in Early Detection and Treatment of Breast Cancer and brought together patholo gists, gynecologists, and radiologists from Denmark, England, France, Italy, Sweden, Switzerland, the German Democratic Republic, and the Federal Republic of Germany. The fIrst session dealt with problems concerned with the biology, patho genesis, and histopathology of early carcinoma of the breast, with special reference to the clinical aspects. The second session was taken up with topi cal developments in the early diagnosis of breast carcinoma and indicated the present limitations of early diagnosis. In the third session the latest results of the experiences by groups working on the treatment of early carci noma of the breast in France, the United Kingdom, Italy, the United States of America, and the Federal Republic of Germany were discussed. The main emphasis lay on conservative treatment methods with complete or partial preservation of the breast. These vary quite widely. Some of the conclusions presented on the basis of long-term clinical studies must be regarded as signifIcant breakthroughs, and at the stage these have reached they must no longer be overlooked. The symposium has highlighted numerous unsolved problems and made it clear that conflicting opinions abound.
Author: Daniel J. Culkin
Publisher: Springer Science & Business Media
ISBN: 1493904612
Category : Medical
Languages : en
Pages : 239
Get Book Here
Book Description
Management of Penile Cancer provides a comprehensive and state-of-the-art overview of the major issues specific to the field of penile cancer. The sections of the book are structured to review the overall scope of issues of penile cancer, including diagnosis and staging, surgical approaches and the treatment of advanced disease. As multidisciplinary care is an integral part of the treatment of penile cancer, this book is unique in the inclusion of collaborating authors from a variety of integrated disciplines, including urology, radiation oncology, medical oncology and reconstructive surgery. Written by recognized experts in their field, Management of Penile Cancer is a unique and valuable resource in the field of penile cancer, both for those currently in training and for those already in clinical or research practice.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547006
Category : Health & Fitness
Languages : en
Pages : 284
Get Book Here
Book Description
Most women who die from cervical cancer, particularly in developing countries, are in the prime of their life. They may be raising children, caring for their family, and contributing to the social and economic life of their town or village. Their death is both a personal tragedy, and a sad and unnecessary loss to their family and their community. Unnecessary, because there is compelling evidence, as this Guide makes clear, that cervical cancer is one of the most preventable and treatable forms of cancer, as long as it is detected early and managed effectively. Unfortunately, the majority of women in developing countries still do not have access to cervical cancer prevention programmes. The consequence is that, often, cervical cancer is not detected until it is too late to be cured. An urgent effort is required if this situation is to be corrected. This Guide is intended to help those responsible for providing services aimed at reducing the burden posed by cervical cancer for women, communities and health systems. It focuses on the knowledge and skills needed by health care providers, at different levels of care.
