Author: George Edward Shuttleworth
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 194
Book Description
Mentally-deficient Children
Author: George Edward Shuttleworth
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 194
Book Description
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 194
Book Description
Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition
Author: Derrick Lonsdale
Publisher: Academic Press
ISBN: 0128103884
Category : Medical
Languages : en
Pages : 358
Book Description
Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition explores thiamine and how its deficiency affects the functions of the brainstem and autonomic nervous system by way of metabolic changes at the level of the mitochondria. Thiamine deficiency derails mitochondrial oxidative metabolism and gives rise to the classic disease of beriberi that, in its early stages, can be considered the prototype for a set of disorders that we now recognize as dysautonomia. This book represents the life's work of the senior author, Dr. Derrick Lonsdale, and a recent collaboration with his co-author Dr. Chandler Marrs. - Presents clinical experience and animal research that have answered questions about thiamine chemistry - Demonstrates that the consumption of empty calories can result in clinical effects that lead to misdiagnosis - Addresses the biochemical changes induced by vitamin deficiency, particularly that of thiamine
Publisher: Academic Press
ISBN: 0128103884
Category : Medical
Languages : en
Pages : 358
Book Description
Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition explores thiamine and how its deficiency affects the functions of the brainstem and autonomic nervous system by way of metabolic changes at the level of the mitochondria. Thiamine deficiency derails mitochondrial oxidative metabolism and gives rise to the classic disease of beriberi that, in its early stages, can be considered the prototype for a set of disorders that we now recognize as dysautonomia. This book represents the life's work of the senior author, Dr. Derrick Lonsdale, and a recent collaboration with his co-author Dr. Chandler Marrs. - Presents clinical experience and animal research that have answered questions about thiamine chemistry - Demonstrates that the consumption of empty calories can result in clinical effects that lead to misdiagnosis - Addresses the biochemical changes induced by vitamin deficiency, particularly that of thiamine
Alpha-1-antitrypsin Deficiency
Author: Noor Kalsheker
Publisher: Academic Press
ISBN: 0128039477
Category : Science
Languages : en
Pages : 262
Book Description
Alpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research. The book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. The editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease. - Provides documentation of the variations in clinical presentation and pathology in a single reference - Presents new insights by pulling together the advances in the understanding of the structure and function of alpha1-antitrypsin deficiency with the genetic variants that cause the disease - Allows for easy reference for the diagnosis of AATD to lead to better therapeutics
Publisher: Academic Press
ISBN: 0128039477
Category : Science
Languages : en
Pages : 262
Book Description
Alpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research. The book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. The editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease. - Provides documentation of the variations in clinical presentation and pathology in a single reference - Presents new insights by pulling together the advances in the understanding of the structure and function of alpha1-antitrypsin deficiency with the genetic variants that cause the disease - Allows for easy reference for the diagnosis of AATD to lead to better therapeutics
Mentally Deficient Children
Author: George Edward Shuttleworth
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 360
Book Description
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 360
Book Description
Prevention of Micronutrient Deficiencies
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030906029X
Category : Medical
Languages : en
Pages : 222
Book Description
Micronutrient malnutrition affects approximately 2 billion people worldwide. The adverse effects of micronutrient deficiencies are profound and include premature death, poor health, blindness, growth stunting, mental retardation, learning disabilities, and low work capacity. Preventing Micronutrient Deficiencies provides a conceptual framework based on past experience that will allow funders to tailor programs to existing regional/country capabilities and to incorporate within these programs the capacity to address multiple strategies (i.e., supplementation/fortification/food-based approaches/public health measures) and multiple micronutrient deficiencies. The book does not offer recommendations on how to alleviate specific micronutrient deficienciesâ€"such recommendations are already available through the publications of diverse organizations, including the U.S. Agency for International Development, the Micronutrient Initiative, World Bank, United Nations Childrens' Fund, and the World Health Organization. Instead, this volume examines key elements in the design and implementation of micronutrient interventions, including such issues as: The importance of iron, vitamin A, and iodine to health. Populations at risk for micronutrient deficiency. Options for successful interventions and their cost. The feasibility of involving societal sectors in the planning and implementation of interventions. Characteristics of successful interventions. The book also contains three in-depth background papers that address the prevention of deficiencies of iron, vitamin A, and iodine.
Publisher: National Academies Press
ISBN: 030906029X
Category : Medical
Languages : en
Pages : 222
Book Description
Micronutrient malnutrition affects approximately 2 billion people worldwide. The adverse effects of micronutrient deficiencies are profound and include premature death, poor health, blindness, growth stunting, mental retardation, learning disabilities, and low work capacity. Preventing Micronutrient Deficiencies provides a conceptual framework based on past experience that will allow funders to tailor programs to existing regional/country capabilities and to incorporate within these programs the capacity to address multiple strategies (i.e., supplementation/fortification/food-based approaches/public health measures) and multiple micronutrient deficiencies. The book does not offer recommendations on how to alleviate specific micronutrient deficienciesâ€"such recommendations are already available through the publications of diverse organizations, including the U.S. Agency for International Development, the Micronutrient Initiative, World Bank, United Nations Childrens' Fund, and the World Health Organization. Instead, this volume examines key elements in the design and implementation of micronutrient interventions, including such issues as: The importance of iron, vitamin A, and iodine to health. Populations at risk for micronutrient deficiency. Options for successful interventions and their cost. The feasibility of involving societal sectors in the planning and implementation of interventions. Characteristics of successful interventions. The book also contains three in-depth background papers that address the prevention of deficiencies of iron, vitamin A, and iodine.
Immune Deficiency
Author: M.D. Cooper
Publisher: Springer Science & Business Media
ISBN: 3642813623
Category : Medical
Languages : en
Pages : 323
Book Description
The subject of immune deficiency has become of special importance for two reasons. First, conditions with well defined defects in the immune system could be analyzed as "experiments of nature" in terms of finding out the accurate biological relevance of the defective link in the immune system. Secondly, the recognition of immune deficiency states has become important in order to provide the patients with the treatment necessary to remedy these defects. With regard to immune deficiency states in patients, these have been instrumental as "experiments of nature" in the revelation by Drs. Good and Cooper and their associates of the two-component structure of the immune system, a discovery which can be consi dered as a major breakthrough in the history of immunopathology. Today's research allows us to go far beyond this basic two component structure with the assessment of disorders affecting either cell to cell interactions or regarding subsets of lymphocyte populations. Furthermore, the association of immune deficiency with distinct enzymatic defects of purine metabolism is opening the door to the molecular level of immune deficiency. Dr. Cooper and Dr. Lawton have succeeded in obtaining the collaboration of the leaders in the field of immune deficiency. In view of the importance of their contributions in scientific and clinical terms, we decided to prepare a book version of the two issues of Seminars in Immunopathology devoted to this subject.
Publisher: Springer Science & Business Media
ISBN: 3642813623
Category : Medical
Languages : en
Pages : 323
Book Description
The subject of immune deficiency has become of special importance for two reasons. First, conditions with well defined defects in the immune system could be analyzed as "experiments of nature" in terms of finding out the accurate biological relevance of the defective link in the immune system. Secondly, the recognition of immune deficiency states has become important in order to provide the patients with the treatment necessary to remedy these defects. With regard to immune deficiency states in patients, these have been instrumental as "experiments of nature" in the revelation by Drs. Good and Cooper and their associates of the two-component structure of the immune system, a discovery which can be consi dered as a major breakthrough in the history of immunopathology. Today's research allows us to go far beyond this basic two component structure with the assessment of disorders affecting either cell to cell interactions or regarding subsets of lymphocyte populations. Furthermore, the association of immune deficiency with distinct enzymatic defects of purine metabolism is opening the door to the molecular level of immune deficiency. Dr. Cooper and Dr. Lawton have succeeded in obtaining the collaboration of the leaders in the field of immune deficiency. In view of the importance of their contributions in scientific and clinical terms, we decided to prepare a book version of the two issues of Seminars in Immunopathology devoted to this subject.
Iodine Deficiency Disorders and Their Elimination
Author: Elizabeth N. Pearce
Publisher: Springer
ISBN: 3319495054
Category : Medical
Languages : en
Pages : 162
Book Description
Iodine is an essential micronutrient and an integral component of the thyroid hormones, which are required for normal growth and development. The iodine deficiency disorders (IDD) encompass a spectrum of adverse health effects including goiter, cretinism, hypothyroidism, growth retardation, and increased pregnancy loss and infant mortality. This volume summarizes the current understanding of the effects of iodine deficiency as well as iodine excess. It also discusses best practices for salt iodization, the mainstay of global IDD prevention efforts, and other forms of food fortification. The effectiveness of iodine supplementation for vulnerable populations, an evolving strategy in many regions, is also described. Low level environmental exposure to chemicals such as perchlorate and thiocyanate, which competitively block thyroidal iodine uptake, appears to be ubiquitous worldwide. There has been recent concern that such environmental exposures might pose a health hazard by inducing or aggravating underlying thyroid dysfunction. This up-to-date volume explores both the effects of iodine deficiency as well as the best strategies for IDD prevention.
Publisher: Springer
ISBN: 3319495054
Category : Medical
Languages : en
Pages : 162
Book Description
Iodine is an essential micronutrient and an integral component of the thyroid hormones, which are required for normal growth and development. The iodine deficiency disorders (IDD) encompass a spectrum of adverse health effects including goiter, cretinism, hypothyroidism, growth retardation, and increased pregnancy loss and infant mortality. This volume summarizes the current understanding of the effects of iodine deficiency as well as iodine excess. It also discusses best practices for salt iodization, the mainstay of global IDD prevention efforts, and other forms of food fortification. The effectiveness of iodine supplementation for vulnerable populations, an evolving strategy in many regions, is also described. Low level environmental exposure to chemicals such as perchlorate and thiocyanate, which competitively block thyroidal iodine uptake, appears to be ubiquitous worldwide. There has been recent concern that such environmental exposures might pose a health hazard by inducing or aggravating underlying thyroid dysfunction. This up-to-date volume explores both the effects of iodine deficiency as well as the best strategies for IDD prevention.
Thiamine Deficiency and Associated Clinical Disorders
Author: David W. McCandless
Publisher: Springer Science & Business Media
ISBN: 1607613115
Category : Medical
Languages : en
Pages : 195
Book Description
Thiamine deficiency and related clinical disorders represent an intriguing area of both basic and clinical investigation. Modern imaging strategies have facilitated the rapid treatment, and potential reversal of these clinical disorders. The fusion of laboratory and clinical knowledge serve as an example of how research can translate to successful treatment. The goal of Thiamine Deficiency and Related Clinical Disorders is to bring together cogent results from basic and clinical investigation and to stimulate further investigations in these areas. This data will be useful to neurologists, internists, nutritionists, biochemists, neurochemists, neuroscientists, and others with interest in thiamine deficiency.
Publisher: Springer Science & Business Media
ISBN: 1607613115
Category : Medical
Languages : en
Pages : 195
Book Description
Thiamine deficiency and related clinical disorders represent an intriguing area of both basic and clinical investigation. Modern imaging strategies have facilitated the rapid treatment, and potential reversal of these clinical disorders. The fusion of laboratory and clinical knowledge serve as an example of how research can translate to successful treatment. The goal of Thiamine Deficiency and Related Clinical Disorders is to bring together cogent results from basic and clinical investigation and to stimulate further investigations in these areas. This data will be useful to neurologists, internists, nutritionists, biochemists, neurochemists, neuroscientists, and others with interest in thiamine deficiency.
Cell Wall Deficient Forms, Third Edition
Author: Lida H. Mattman
Publisher: CRC Press
ISBN: 9780849387678
Category : Science
Languages : en
Pages : 464
Book Description
Numerous infectious diseases are described as idiopathic, meaning that "the cause is a complete mystery." For many idiopathic diseases, the causes become clear when certain techniques are applied to the patient's blood or other tissues. Cell Wall Deficient Forms: Stealth Pathogens, Third Edition describes these techniques. In the case of tuberculosis, a disease that has recently regained importance because the strains have acquired antibiotic resistance, the book describes a method that is widely used abroad. This method typically renders the diagnosis within 72 hours. The book examines a plethora of issues and provides answers to the following questions: What organism should be added to the childhood vaccine, especially for boys? What bacteria in its pleomorphic state is found in direct smears of synovial fluid of rheumatoid arthritis cases? In which chronic diseases ( presently considered as being of unknown origin) is an acid-fast organism routinely found in smears of 72 hour blood cultures? Which "bacterium" has a life cycle in the human erythrocyte as complex as that of Plasmodium malaria? Which common pathogen's L Form can permanently damage myocardium mammaliam? Cell Wall Deficient Forms: Stealth Pathogens, Third Edition discloses significant aspects of microbiology, aspects that are not taught, and which go unrecognized in the clinical laboratory.
Publisher: CRC Press
ISBN: 9780849387678
Category : Science
Languages : en
Pages : 464
Book Description
Numerous infectious diseases are described as idiopathic, meaning that "the cause is a complete mystery." For many idiopathic diseases, the causes become clear when certain techniques are applied to the patient's blood or other tissues. Cell Wall Deficient Forms: Stealth Pathogens, Third Edition describes these techniques. In the case of tuberculosis, a disease that has recently regained importance because the strains have acquired antibiotic resistance, the book describes a method that is widely used abroad. This method typically renders the diagnosis within 72 hours. The book examines a plethora of issues and provides answers to the following questions: What organism should be added to the childhood vaccine, especially for boys? What bacteria in its pleomorphic state is found in direct smears of synovial fluid of rheumatoid arthritis cases? In which chronic diseases ( presently considered as being of unknown origin) is an acid-fast organism routinely found in smears of 72 hour blood cultures? Which "bacterium" has a life cycle in the human erythrocyte as complex as that of Plasmodium malaria? Which common pathogen's L Form can permanently damage myocardium mammaliam? Cell Wall Deficient Forms: Stealth Pathogens, Third Edition discloses significant aspects of microbiology, aspects that are not taught, and which go unrecognized in the clinical laboratory.
Nutritional Deficiency
Author: Pinar Erkekoglu
Publisher: BoD – Books on Demand
ISBN: 9535124374
Category : Science
Languages : en
Pages : 208
Book Description
Intake of a sufficient diet will provide an individual to live a healthy and functional life. However, poor intake of different nutritional components, such as proteins, vitamins, minerals, and trace elements, may lead to health problems that can cause morbidity and finally mortality. Assessment of nutritional status involves physical examination, comprehensive evaluation of biochemical tests, body composition, and organ functions. Both high and low intake of nutritional elements may lead to significant health impairment. The main aim of the book Nutritional Deficiency is to determine the relationships between nutritional status and general health. The authors, who are contributing to the book, particularly focused on iron, vitamin D, and zinc deficiencies, which are global health problems. Besides, some chapters mention the impact of different nutritional deficiencies in susceptible periods of life, such as pregnancy and elderly. Besides, as a result of these deficiencies, different health conditions, such as depression, anemia, loss of neuronal plasticity, and cancer, are widely scrutinized in the book. One chapter mainly focuses on the effects of disasters on nutrition and disaster-caused malnutrition in underdeveloped countries. This book will widen the knowledge store of the readers on the effects of nutrition on general health, how nutritional deficiencies arise when there is a health problem, and how the nutritional status affects susceptible populations.
Publisher: BoD – Books on Demand
ISBN: 9535124374
Category : Science
Languages : en
Pages : 208
Book Description
Intake of a sufficient diet will provide an individual to live a healthy and functional life. However, poor intake of different nutritional components, such as proteins, vitamins, minerals, and trace elements, may lead to health problems that can cause morbidity and finally mortality. Assessment of nutritional status involves physical examination, comprehensive evaluation of biochemical tests, body composition, and organ functions. Both high and low intake of nutritional elements may lead to significant health impairment. The main aim of the book Nutritional Deficiency is to determine the relationships between nutritional status and general health. The authors, who are contributing to the book, particularly focused on iron, vitamin D, and zinc deficiencies, which are global health problems. Besides, some chapters mention the impact of different nutritional deficiencies in susceptible periods of life, such as pregnancy and elderly. Besides, as a result of these deficiencies, different health conditions, such as depression, anemia, loss of neuronal plasticity, and cancer, are widely scrutinized in the book. One chapter mainly focuses on the effects of disasters on nutrition and disaster-caused malnutrition in underdeveloped countries. This book will widen the knowledge store of the readers on the effects of nutrition on general health, how nutritional deficiencies arise when there is a health problem, and how the nutritional status affects susceptible populations.