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Author: Kiyoshi Nagai
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 302
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Book Description
The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.
Author: Kiyoshi Nagai
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 302
Get Book Here
Book Description
The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.
Author: Marlene Oeffinger
Publisher: Springer Nature
ISBN: 3030314340
Category : Science
Languages : en
Pages : 318
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Book Description
The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting on the mRNAs, leading to a properly folded complex. This book shows how new technologies have led to a better understanding of these processes and their connected diseases.The book is written for scientists in fundamental and applied biomedical research working on different aspects of gene regulation. It is also targeted to an audience that is not implicated in these fields directly, but wants to gain a better understanding of mRNA biology.
Author: Buddhi Prakash Jain
Publisher: Academic Press
ISBN: 0323983960
Category : Science
Languages : en
Pages : 310
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Book Description
Understanding Cancer: From Basics to Therapeutics presents both basic concepts and research prospects in the field of cancer biology. This book summarizes the fundamental aspects of cancer and presents a detailed description of molecular aspects as well as treatment and therapeutics for patients. The book is divided into three parts: the first part deals with the basics of cancer, including etiology and medical diagnosis; the second part explores the molecular mechanisms associated with cancer, focusing on cell cycle and apoptosis, cell metabolism, gene regulation, epigenetics, and stem cells; and the third part is dedicated to therapeutics, discussing chemo and radiotherapies, gene, hormone, herbal, and immunotherapies. It is a valuable resource for cancer researchers, oncologists, graduate students, and biomedical researchers who need to understand the fundamental topics related to cancer to apply to their research work or clinical setting. - Presents fundamental aspects of cancer in a didactic way to make the content easily applicable by readers - Illustrates the content through detailed images developed by the authors exclusively for the book to facilitate comprehension - Summarizes the content of each chapter with several tables and schematic diagrams for quick consult
Author: Eric C. Schirmer
Publisher: Springer Science & Business Media
ISBN: 1489980326
Category : Medical
Languages : en
Pages : 610
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Book Description
"Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer."
Author: Laurence A. Cole
Publisher: Academic Press
ISBN: 0128096861
Category : Science
Languages : en
Pages : 198
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Book Description
Biology of Life: Biochemistry, Physiology and Philosophy provides foundational coverage of the field of biochemistry for a different angle to the traditional biochemistry text by focusing on human biochemistry and incorporating related elements of evolution to help further contextualize this dynamic space. This unique approach includes sections on early human development, what constitutes human life, and what makes it special. Additional coverage on the differences between the biochemistry of prokaryotes and eukaryotes is also included. The center of life in prokaryotes is considered to be photosynthesis and sugar generation, while the center of life in eukaryotes is sugar use and oxidative phosphorylation. This unique reference will inform specialized biochemistry courses and researchers in their understanding of the role biochemistry has in human life. - Contextualizes the field of biochemistry and its role in human life - Includes dedicated sections on human reproduction and human brain development - Provides extensive coverage on biochemical energetics, oxidative phosphorylation, photosynthesis, and carbon monoxide-acetate pathways
Author: Weidong Yang
Publisher: Springer
ISBN: 3319773097
Category : Science
Languages : en
Pages : 277
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Book Description
Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.
Author:
Publisher: Elsevier
ISBN: 0124171788
Category : Science
Languages : en
Pages : 553
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Book Description
Volume 122 of Methods in Cell Biology describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (including mammalian cells, Xenopus, C. elegans, yeast). The volume enables investigators to analyze nuclear pore complex structure, assembly, and dynamics; to evaluate protein and RNA trafficking through the nuclear envelope; and to design in vivo or in vitro assays appropriate to their research needs. Beyond the study of nuclear pores and transport as such, these protocols will also be helpful to scientists characterizing gene regulation, signal transduction, cell cycle, viral infections, or aging. The NPC being one of the largest multiprotein complexes in the cell, some protocols will also be of interest for people currently characterizing other macromolecular assemblies. This book is thus designed for laboratory use by graduate students, technicians, and researchers in many molecular and cellular disciplines. - Describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (mammalian cells, Xenopus, C. elegans, yeast) - Chapters are written by experts in the field - Cutting-edge material
Author: Gary Whitson
Publisher: Elsevier
ISBN: 0323154468
Category : Science
Languages : en
Pages : 359
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Book Description
Nuclear-Cytoplasmic Interactions in the Cell Cycle
Author: Leslie P. Gartner
Publisher: Elsevier Health Sciences
ISBN: 0323390684
Category : Medical
Languages : en
Pages : 750
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Book Description
Thoroughly updated to reflect all of the latest concepts and advances in the field, this concise, extensively illustrated text presents the basic science and clinical application of cellular and molecular biology. Functioning as a combined text and atlas, it is essentially two books for the price of one providing a comprehensive, visually engaging histology education from the ground up. Illustrations, tables, chapter summaries and multiple choice questions facilitate comprehension of concepts, and clinical correlations underscore the practical relevance of the material. - Superb illustrations—including photomicrographs, electron micrographs, schematic diagrams and drawings—provide a visual grasp and easier retention of difficult concepts. - Clinical correlations throughout the text demonstrate clinical applications and reinforce the idea that histology is pertinent not only to pathology and physiology, but in fact comprises one of the essential bases of clinical practice. - New! "Pathological Considerations" section at the end of each chapter. - Helpful tables provide an at-a-glance summary statement of key points. - Bolded key terms, bulleted lists and chapter summaries emphasize the "need to know" information in every chapter. - A combination of USMLE-style questions and image based questions in each chapter.
Author: Horst Feldmann
Publisher: John Wiley & Sons
ISBN: 3527659196
Category : Science
Languages : en
Pages : 1
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Book Description
Finally, a stand-alone, all-inclusive textbook on yeast biology. Based on the feedback resulting from his highly successful monograph, Horst Feldmann has totally rewritten he contents to produce a comprehensive, student-friendly textbook on the topic. The scope has been widened, with almost double the content so as to include all aspects of yeast biology, from genetics via cell biology right up to biotechnology applications. The cell and molecular biology sections have been vastly expanded, while information on other yeast species has been added, with contributions from additional authors. Naturally, the illustrations are in full color throughout, and the book is backed by a complimentary website. The resulting textbook caters to the needs of an increasing number of students in biomedical research, cell and molecular biology, microbiology and biotechnology who end up using yeast as an important tool or model organism.
