Next-generation DNA Sequencing Informatics PDF Download
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Author: Stuart M. Brown
Publisher:
ISBN: 9781621821236
Category : MEDICAL
Languages : en
Pages : 0
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Book Description
"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"
Author: Stuart M. Brown
Publisher:
ISBN: 9781621821236
Category : MEDICAL
Languages : en
Pages : 0
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Book Description
"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"
Author: Naiara Rodríguez-Ezpeleta
Publisher: Springer Science & Business Media
ISBN: 1461407826
Category : Science
Languages : en
Pages : 258
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Book Description
Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.
Author: ANTONIO MONLEON-GETINO
Publisher: Lulu.com
ISBN: 0244988714
Category : Technology & Engineering
Languages : en
Pages : 40
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Book Description
Un llibre introductori per entendre la bioinformàtica i les tècniques modernes desequenciació (Next Generation Sequenting).Next Generation Sequencing (NGS) és un terme per identificar una tecnologiade seqüenciació de l'ADN i ARN que ha revolucionat el món de la genómica.NGS engloba totes les tecnologies destinades a dur a terme la seqüenciaciómassiva a gran escala de qualsevol àcid nucleic a la actualitat.Les possibilitats de la investigació mèdica i biològica s'han multiplicat durant lesdues últimes dècades amb les tècniques de seqüenciació i especialment ambNGS. NGS és una tècnica molt potent que permet la detecció de tots els tipusde variacions de l'ADN (petites substitucions, delecions o insercions, així comgrans delecions genòmiques d'exons, inversions o translocacions).Aquest llibre ofereix d'una manera succinta què és i com es realitza laseqüenciació amb NGS.
Author: Ali Masoudi-Nejad
Publisher: Springer Science & Business Media
ISBN: 1461477263
Category : Medical
Languages : en
Pages : 92
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Book Description
The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about sequencing and assembly methods together, helps both biologists and computer scientists to get a clear idea about the field. Chapters will include information about new sequencing technologies such as ChIp-seq, ChIp-chip, and De Novo sequence assembly.
Author: Xinkun Wang
Publisher: CRC Press
ISBN: 1482217899
Category : Mathematics
Languages : en
Pages : 252
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Book Description
A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi
Author: Sun Kim
Publisher: Artech House Publishers
ISBN:
Category : Computers
Languages : en
Pages : 288
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Book Description
The 2003 completion of the Human Genome Project was just one step in the evolution of DNA sequencing. This trailblazing work gives researchers unparalleled access to state-of-the-art DNA sequencing technologies, new algorithmic sequence assembly techniques, and emerging methods for both resequencing and genome analysis.
Author: Daniel Branton
Publisher: World Scientific
ISBN: 9813270624
Category : Science
Languages : en
Pages : 217
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Book Description
This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics — from electricity to biochemistry, protein structure, molecular engineering, and informatics — that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.
Author: Bhanu P. Chowdhary
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 376
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Book Description
This publication provides an update on the current status of gene maps in different livestock and pet/companion animal species. The findings summarized in species specific commentaries and original articles testify the rapid advances made in the field of animal genomics. Of significant interest is the fact that current investigations are providing headways for two important and exciting research fronts: targeted high-resolution mapping leading to the application of genomic information in addressing questions of economic and biological significance in animals, and the initiation of whole genome sequencing projects for some of the animal species. Like in humans and mice, this will set the stage for a new level of research and real time complex analysis of the genomes of these species. Animal Genomics signifies the beginning of a new era in this field and celebrates the achievements of the past 20 years of genomics research. It will be of special interest to researchers involved in genome analysis - both gross chromosomal as well as molecular - in various animal species, and to comparative and evolutionary geneticists.
Author: Paul L. Bartel
Publisher: Oxford University Press, USA
ISBN: 9780195109382
Category : Carrier proteins
Languages : en
Pages : 362
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Book Description
This volume, part of the Advances in Molecular Biology series, presents work by pioneers in the field and is the first publication devoted solely to the yeast two-hybrid system. It includes detailed protocols, practical advice on troubleshooting, and suggestions for future development. In addition, it illustrates how to construct an activation domain hybrid library, how to identify mutations that disrupt an interaction, and how to use the system in mammalian cells. Many of the contributors have developed new applications and variations of the technique.
Author: Jerzy Kulski
Publisher: BoD – Books on Demand
ISBN: 9535122401
Category : Medical
Languages : en
Pages : 466
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Book Description
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
