ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS

ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS PDF Author: Mr. Nagineni Sudarshan Rao
Publisher: JEC PUBLICATION
ISBN: 9358506393
Category : Medical
Languages : en
Pages : 291

Get Book Here

Book Description
Welcome to the world of Advanced Biopharmaceutics & Pharmacokinetics, a field that lies at the intersection of pharmaceutical science, medicine, and technology. This book represents an exploration into the intricate mechanisms governing the fate of drugs in the human body, the evolving landscape of drug delivery systems, and the cutting-edge methodologies shaping the future of pharmacokinetics. In the ever-evolving landscape of pharmaceuticals, the quest for optimizing drug delivery, enhancing therapeutic efficacy, and minimizing adverse effects has become increasingly complex. This book seeks to unravel these complexities by delving into the advanced principles of biopharmaceutics and pharmacokinetics, providing a comprehensive guide for researchers, practitioners, and students in the pharmaceutical sciences. The journey into Advanced Biopharmaceutics & Pharmacokinetics begins with a thorough examination of the fundamental concepts that underpin drug absorption, distribution, metabolism, and excretion. From there, we navigate through the intricacies of drug formulation and delivery systems, exploring the latest innovations in nanomedicine, biosimilars, and targeted drug delivery. Throughout the chapters, we highlight the pivotal role of pharmacokinetics in drug development, emphasizing its importance in optimizing dosage regimens, understanding drug interactions, and individualizing therapies in the era of precision medicine. The integration of advanced technologies, such as systems pharmacology and therapeutic drug monitoring, further enriches the discussion, offering a glimpse into the future of pharmacokinetic research.

ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS

ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS PDF Author: Mr. Nagineni Sudarshan Rao
Publisher: JEC PUBLICATION
ISBN: 9358506393
Category : Medical
Languages : en
Pages : 291

Get Book Here

Book Description
Welcome to the world of Advanced Biopharmaceutics & Pharmacokinetics, a field that lies at the intersection of pharmaceutical science, medicine, and technology. This book represents an exploration into the intricate mechanisms governing the fate of drugs in the human body, the evolving landscape of drug delivery systems, and the cutting-edge methodologies shaping the future of pharmacokinetics. In the ever-evolving landscape of pharmaceuticals, the quest for optimizing drug delivery, enhancing therapeutic efficacy, and minimizing adverse effects has become increasingly complex. This book seeks to unravel these complexities by delving into the advanced principles of biopharmaceutics and pharmacokinetics, providing a comprehensive guide for researchers, practitioners, and students in the pharmaceutical sciences. The journey into Advanced Biopharmaceutics & Pharmacokinetics begins with a thorough examination of the fundamental concepts that underpin drug absorption, distribution, metabolism, and excretion. From there, we navigate through the intricacies of drug formulation and delivery systems, exploring the latest innovations in nanomedicine, biosimilars, and targeted drug delivery. Throughout the chapters, we highlight the pivotal role of pharmacokinetics in drug development, emphasizing its importance in optimizing dosage regimens, understanding drug interactions, and individualizing therapies in the era of precision medicine. The integration of advanced technologies, such as systems pharmacology and therapeutic drug monitoring, further enriches the discussion, offering a glimpse into the future of pharmacokinetic research.

The Future Leader

The Future Leader PDF Author: Jacob Morgan
Publisher: John Wiley & Sons
ISBN: 1119518377
Category : Business & Economics
Languages : en
Pages : 75

Get Book Here

Book Description
WINNER OF CMI MANAGEMENT BOOK OF THE YEAR 2021 Are you a future-ready leader? Based on exclusive interviews with over 140 of the world's top CEOs and a survey of nearly 14,000 people. Do you have the right mindsets and skills to be able to lead effectively in the next ten years and beyond? Most individuals and organizations don’t even know what leadership will look like in the future. Until now. There has been a lot written about leadership for the present day, but the world is changing quickly. What worked in the past won’t work in the future. We need to know how to prepare leaders who can successfully navigate and guide us through the next decade and beyond. How is leadership changing, and why? How ready are leaders today for these changes? What should leaders do now? To answer these questions, Jacob interviewed over 140 CEOs from companies like Unilever, Mastercard, Best Buy, Oracle, Verizon, Kaiser, KPMG, Intercontinental Hotels Group, Yum! Brands, Saint-Gobain, Dominos, Philip Morris International, and over a hundred others. Jacob also partnered with Linkedin to survey almost 14,000 of their members around the globe to see how CEO insights align with employee perspectives The majority of the world's top business leaders that Jacob interviewed believe that while some core aspects of leadership will remain the same, such as creating a vision and executing on strategy, leaders of the future will need a new arsenal of skills and mindsets to succeed. What emerged from all of this research is the most accurate groundbreaking book on the future of leadership, which shares exclusive insights from the world's top CEOs and never before seen research. After reading it, you will: Learn the greatest trends impacting the future of leadership and their implications Understand the top skills and mindsets that leaders of the future will need to possess and how to learn them Change your perception of who a leader is and what leadership means Tackle the greatest challenges that leaders of the future will face See the gap that exists between what CEOs identified versus what employees are actually experiencing Become a future-ready leader This is the book that you, your team, and your organization must read in order to lead in the future of work.

Theories, Methods, Practices, and Fields of Digital Social Research

Theories, Methods, Practices, and Fields of Digital Social Research PDF Author: Gabriella Punziano
Publisher: Frontiers Media SA
ISBN: 2832551467
Category : Social Science
Languages : en
Pages : 290

Get Book Here

Book Description
The digital, in the form of technologies, scenarios, objects, processes, and relational and interactional structures, is increasingly becoming central to understanding culture, society, human experience, and the social world. It permeates our society’s practices, symbols, and shared meanings, and it makes old distinctions, such as the one between online and offline, real and virtual, and material and immaterial, obsolete. It also introduces digitally native objects of research, such as cyber-bullying and digital identities, which have a direct impact on mainstream sociological problems.

Handbook of Research on Teaching With Virtual Environments and AI

Handbook of Research on Teaching With Virtual Environments and AI PDF Author: Panconesi, Gianni
Publisher: IGI Global
ISBN: 179987639X
Category : Education
Languages : en
Pages : 811

Get Book Here

Book Description
The increasingly pervasive use of digital technology has catapulted society into an interconnected world where the natural boundaries between humankind and machine, virtual and real, individual and community have become less perceptible. As individuals interact with different digital technologies, they must build a digital intelligence, which must be further cultivated as it is a key competency for the future of school and work. Digital intelligence includes understanding the mutual strengths between people and technology, as well as developing an awareness in the use of digital tools in order to avoid common threats such as cyberbullying, addiction to video games, techno-stress, and more. As adolescents continue to engage with virtual reality and 3D virtual worlds where the online and offline overlap and coincide, it is important to build this intelligence as well as utilize these technologies to promote successful learning. The Handbook of Research on Teaching With Virtual Environments and AI explores the new personalized educational opportunities that are available with digital technology and virtual environments that can be used within education. This book focuses on the use of these tools and how to navigate the use of new technologies such as AI and virtual environments for educational practices. While highlighting topics such as virtual worlds, game-based learning, intelligent tutoring, augmented reality, and more, this book is ideal for teachers, administrators, technologists, educational software developers, IT specialists, practitioners, researchers, academicians, and students interested in how virtual environments and AI are being implemented in teaching practices.

Your First Leadership Job

Your First Leadership Job PDF Author: Tacy M. Byham
Publisher: John Wiley & Sons
ISBN: 1118911954
Category : Business & Economics
Languages : en
Pages : 295

Get Book Here

Book Description
Becoming the Very Best First-Time Leader Congratulations! You’re now in charge. Perhaps it’s your first time as a leader, or maybe you want to fine-tune your skills. Either way, you’ve begun one of the most rewarding chapters of your career. But, like many beginnings, the first few years can be challenging. Fortunately, you don’t have to tackle this challenge on your own. Your First Leadership Job gives you practical advice straight from others who have walked in your shoes. Not only does it include dozens of tools to ensure your success, but it’s also based on the authors’ and DDI’s extensive experience and research, which ultimately has led to the development of millions of leaders around the world. In fact, a quarter-million leaders will be developed this year alone via DDI training. Your First Leadership Job is divided into two sections. Part 1 introduces the concept of catalyst leader—one who sparks energy, passion, and commitment in others. Your transition to catalyst leader is a major step in your leadership journey. This book provides essential tips to put you on the catalyst path. Ultimately, leadership is about the many conversations—frequent, clear, authentic, and occasionally difficult—that you will have daily. Your First Leadership Job builds awareness of the fundamental skills you’ll come to rely on to make every one of these interactions successful. Part 2 devotes 13 chapters to critical core leadership competencies, including coaching for success, hiring the best employees, turning dreaded appraisals into discussions that propel performance, and handling difficult employees. It also includes a chapter for first-time female leaders. Look at Your First Leadership Job as an indispensable companion to becoming an awesome leader—one who will make a positive, lasting impact on your team, family, and career. Visit www.yourfirstleadershipjob.com to learn more.

Metadata

Metadata PDF Author: Jian Qin
Publisher: American Library Association
ISBN: 0838948634
Category : Language Arts & Disciplines
Languages : en
Pages : 640

Get Book Here

Book Description
This benchmark text is back in a new edition thoroughly updated to incorporate developments and changes in metadata and related domains. Zeng and Qin provide a solid grounding in the variety and interrelationships among different metadata types, offering a comprehensive look at the metadata schemas that exist in the world of library and information science and beyond. Readers will gain knowledge and an understanding of key topics such as the fundamentals of metadata, including principles of metadata, structures of metadata vocabularies, and metadata descriptions; metadata building blocks, from modeling to defining properties, from designing application profiles to implementing value vocabularies, and from specification generating to schema encoding, illustrated with new examples; best practices for metadata as linked data, the new functionality brought by implementing the linked data principles, and the importance of knowledge organization systems; resource metadata services, quality measurement, and interoperability approaches; research data management concepts like the FAIR principles, metadata publishing on the web and the recommendations by the W3C in 2017, related Open Science metadata standards such as Data Catalog Vocabulary (DCAT) version 2, and metadata-enabled reproducibility and replicability of research data; standards used in libraries, archives, museums, and other information institutions, plus existing metadata standards’ new versions, such as the EAD 3, LIDO 1.1, MODS 3.7, DC Terms 2020 release coordinating its ISO 15396-2:2019, and Schema.org’s update in responding to the pandemic; and newer, trending forces that are impacting the metadata domain, including entity management, semantic enrichment for the existing metadata, mashup culture such as enhanced Wikimedia contents, knowledge graphs and related processes, semantic annotations and analysis for unstructured data, and supporting digital humanities (DH) through smart data. A supplementary website provides additional resources, including examples, exercises, main takeaways, and editable files for educators and trainers.

Enzyme- and Transporter-Based Drug-Drug Interactions

Enzyme- and Transporter-Based Drug-Drug Interactions PDF Author: K. Sandy Pang
Publisher: Springer Science & Business Media
ISBN: 1441908404
Category : Medical
Languages : en
Pages : 742

Get Book Here

Book Description
Germination of the thought of "Enzymatic- and Transporter-Based Drug-Drug Interactions: Progress and Future Challenges" Proceedings came about as part of the annual meeting of The American Association of Pharmaceutical Scientists (AAPS) that was held in San Diego in November of 2007. The attendance of workshop by more than 250 pharmaceutical scientists reflected the increased interest in the area of drug-drug interactions (DDIs), the greater focus of PhRMA, academia, and regulatory agencies, and the rapid pace of growth in knowledge. One of the aims of the workshop was to address the progress made in quantitatively predicting enzyme- and transporter-based DDIs as well as highlighted areas where such predictions are poor or areas that remain challenging for the future. Because of the serious clinical implications, initiatives have arisen from the FDA (http://www.fda.gov/cber/gdlns/interactstud.htm) to highlight the importance of enzyme- and transporter-based DDIs. During the past ten to fifteen years, we have come to realize that transporters, in addition to enzymes, play a vital role in drug elimination. Such insight has been possible because of the continued growth in PK-ADME (pharmacokinetics-absorption-distribution-metabolism-excretion) knowledge, fueled by further advances in molecular biology, greater availability of human tissues, and the development of additional and sophisticated model systems and sensitive assay methods for studying drug metabolism and transport in vitro and in vivo. This has sparked an in-depth probing into mechanisms surrounding DDIs, resulting from ligand-induced changes in nuclear receptors, as well as alterations in transporter and enzyme expression and function. Despite such advances, the in vitro and in vivo study of drug interactions and the integration of various data sets remain challenging. Therefore, it has become apparent that a proceeding that serves to encapsulate current strategies, approaches, methods and applications is necessary. As Editors, we have assembled a number of opinion leaders and asked them to contribute chapters surrounding these issues. Many of these are the original Workshop speakers whereas others had been selected specially to contribute on topics related to basic and applied information that had not been covered in other reference texts on DDI. The resulting tome, entitled Enzyme- and Transporter-Based Drug Interactions: Progress and Future Challenges, comprises of four sections. Twenty-eight chapters covering various topics and perspectives related to the subject of metabolic and transporter-based drug-drug interactions are presented.

Cracking the Leadership Code

Cracking the Leadership Code PDF Author: Alain Hunkins
Publisher: John Wiley & Sons
ISBN: 1119675545
Category : Business & Economics
Languages : en
Pages : 288

Get Book Here

Book Description
Become the effective, proactive leader you aspire to be with this practical tool kit for leading people and organizations Yes, you can learn the skills to effectively lead people, organizations, and employees. With the right motivation and knowledge, you can be a leader who knows what it takes to succeed. Throughout his extensive experience in training leaders, author Alain Hunkins discovered that many leaders shared a common trait. They were mainly focused on what they were doing but not so focused on how they were doing it, especially when it came to working with other people. By strengthening their leadership capabilities, they could become trusted leaders within their organization, improve employee communications, and build bridges across hierarchies. Cracking the Leadership Code shares the valuable principles and practices that Hunkins developed and refined during the 20+ years he’s worked with leaders. When you crack the code, you’ll have a new operating model for organizational leadership that will help your teams thrive in a 21st century economy. Discover the brain science behind leading people Get inspired by real life leadership stories Use a practical leadership tool kit to become a better leader Learn how to communicate, influence, and persuade others, more effectively than ever before With this book as a resource, you’ll have a new perspective, a new framework, and new tools at your disposal, readily available to guide your leadership. You’ll learn to establish proactive, leader-follower relationships. To do this, you’ll use the interconnected elements of Connection, Communication, and Collaboration. When you learn from the author’s insightful experiences working with organizations around the world, you can accelerate your leadership development and become the leader you’ve always aspired to be.

The Outward Mindset

The Outward Mindset PDF Author: , The Arbinger Institute
Publisher: Berrett-Koehler Publishers
ISBN: 1626567174
Category : Business & Economics
Languages : en
Pages : 189

Get Book Here

Book Description
Unknowingly, too many of us operate from an inward mindset—a narrow-minded focus on self-centered goals and objectives. When faced with personal ineffectiveness or lagging organizational performance, most of us instinctively look for quick-fix behavioral band-aids, not recognizing the underlying mindset at the heart of our most persistent challenges. Through true stories and simple yet profound guidance and tools, The Outward Mindset enables individuals and organizations to make the one change that most dramatically improves performance, sparks collaboration, and accelerates innovation—a shift to an outward mindset.

Machine Learning and Knowledge Discovery in Databases. Research Track and Demo Track

Machine Learning and Knowledge Discovery in Databases. Research Track and Demo Track PDF Author: Albert Bifet
Publisher: Springer Nature
ISBN: 3031703715
Category :
Languages : en
Pages : 487

Get Book Here

Book Description