Cytotoxic T-Lymphocytes in Human Viral and Malaria Infections

Cytotoxic T-Lymphocytes in Human Viral and Malaria Infections PDF Author: Michael B.A. Oldstone
Publisher: Springer Science & Business Media
ISBN: 3642785301
Category : Medical
Languages : en
Pages : 215

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Book Description
Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of CD8 genetically deficient (knock-out) mice. In this volume, data for the role that CTL play in human infectious diseases is presented. As such, this represents the first volume in which such information from several different viral and protozoan infections is brought together.

Cytotoxic T-Lymphocytes in Human Viral and Malaria Infections

Cytotoxic T-Lymphocytes in Human Viral and Malaria Infections PDF Author: Michael B.A. Oldstone
Publisher: Springer Science & Business Media
ISBN: 3642785301
Category : Medical
Languages : en
Pages : 215

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Book Description
Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of CD8 genetically deficient (knock-out) mice. In this volume, data for the role that CTL play in human infectious diseases is presented. As such, this represents the first volume in which such information from several different viral and protozoan infections is brought together.

Cytotoxic T Lymphocytes in Humans Exposed to Plasmodium Falciparum by Immunization Or Natural Exposure

Cytotoxic T Lymphocytes in Humans Exposed to Plasmodium Falciparum by Immunization Or Natural Exposure PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 18

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Book Description
Malaria is one of the most important infectious diseases in the world. It is estimated that 2.1 billion people live in areas of the world where malaria is transmitted and that there are 100-300 million new cases of malaria and one to two million deaths caused by malaria every year (WHO 1991). In the past 10-20 years, the severity of the malaria problem has worsened in many areas because of the emergence of drug-resistant strains of the parasite, resistance to insecticides of the Anopheles sp. mosquitoes that transmit the disease, socioeconomic problems that have led to a decreased capacity to optimally utilize existing tools to combat the disease, and movement of nonimmune populations into areas where malaria is transmitted. Accordingly, there are now renewed efforts to control this disease. A major focus of research efforts is to develop vaccines against malaria, including vaccines designed to produce protective cytotoxic T lymphocytes (CTL; HOFFMAN et al. 1991). To understand how such vaccines might work, it is important to understand the life cycle of the parasite.

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description


Persistent Viral Infections

Persistent Viral Infections PDF Author: R. Ahmed
Publisher: Wiley-Blackwell
ISBN:
Category : Medical
Languages : en
Pages : 754

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Book Description
Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.

Nijkamp and Parnham's Principles of Immunopharmacology

Nijkamp and Parnham's Principles of Immunopharmacology PDF Author: Michael J. Parnham
Publisher: Springer Nature
ISBN: 3030108112
Category : Medical
Languages : en
Pages : 888

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Book Description
Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

CD8+ Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Infection

CD8+ Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Infection PDF Author: Jane C. Gamberg
Publisher:
ISBN:
Category : HIV infections
Languages : en
Pages : 394

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Book Description


Chimpanzees in Biomedical and Behavioral Research

Chimpanzees in Biomedical and Behavioral Research PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309220424
Category : Science
Languages : en
Pages : 200

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Book Description
For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.

Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Cytotoxic T Cells in HIV and Other Retroviral Infections

Cytotoxic T Cells in HIV and Other Retroviral Infections PDF Author: Paul Racz
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 198

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Book Description


Role of Cytotoxic T Lymphocytes in the Control of Human Immunodeficiency Virus Type-1 Infection

Role of Cytotoxic T Lymphocytes in the Control of Human Immunodeficiency Virus Type-1 Infection PDF Author: Graham S. Ogg
Publisher:
ISBN:
Category : HIV infections
Languages : en
Pages : 372

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Book Description