Cross-Over Experiments

Cross-Over Experiments PDF Author: David Ratkowsky
Publisher: CRC Press
ISBN: 1000723526
Category : Mathematics
Languages : en
Pages : 468

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Book Description
Developing a model-based approach that enables any cross-over trial, of any degree of imbalance, to be analyzed both for direct effects and for residual effects, using consistent procedures that employ commercially available statistical software, this text offers a guide to the analysis of cross-over designs.;Illustrating practical applications throughout with examples, this book: emphasizes the importance of choosing highly efficient designs that separate treatment and carryover effects; demonstrates the exact methodology needed to handle the analysis of data; presents a new methodology for the analysis of binary and categorical data; and considers the effects of blocking. The appendices facilitate the choosing of an appropriate design for every experimental need.

Cross-Over Experiments

Cross-Over Experiments PDF Author: David Ratkowsky
Publisher: CRC Press
ISBN: 1000723526
Category : Mathematics
Languages : en
Pages : 468

Get Book Here

Book Description
Developing a model-based approach that enables any cross-over trial, of any degree of imbalance, to be analyzed both for direct effects and for residual effects, using consistent procedures that employ commercially available statistical software, this text offers a guide to the analysis of cross-over designs.;Illustrating practical applications throughout with examples, this book: emphasizes the importance of choosing highly efficient designs that separate treatment and carryover effects; demonstrates the exact methodology needed to handle the analysis of data; presents a new methodology for the analysis of binary and categorical data; and considers the effects of blocking. The appendices facilitate the choosing of an appropriate design for every experimental need.

Design and Analysis of Cross-Over Trials, Second Edition

Design and Analysis of Cross-Over Trials, Second Edition PDF Author: Byron Jones
Publisher: CRC Press
ISBN: 1420036092
Category : Mathematics
Languages : en
Pages : 390

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Book Description
The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials. Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include: A new chapter on bioequivalence Recently developed methods for analyzing longitudinal continuous and categorical data Real-world examples using the SAS system A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.

Optimal Crossover Designs

Optimal Crossover Designs PDF Author: Aloke Dey
Publisher: World Scientific
ISBN: 981281843X
Category : Science
Languages : en
Pages : 238

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Book Description
This monograph presents a comprehensive and up-to-date account of the developments in optimality aspects of crossover designs. Crossover designs are immensely useful in various areas of human investigation including agriculture, animal nutrition, clinical trials, pharmaceutical studies, biological assays, weather modification experiments, sensory evaluation of food products and learning experiments. Research on the optimality aspects of crossover designs has developed only in the last three decades, and it has now emerged as a potential field for further investigation. This book is the first comprehensive treatise on this subject. It covers optimal crossover designs at length by consolidating vast amounts of material from the literature, and includes many recent and deep results. It is expected that this book will not only provide a one-stop reference for the available results, but also encourage further research in this area of substantial practical relevance.

Advanced Organic Chemistry

Advanced Organic Chemistry PDF Author: Reinhard Bruckner
Publisher: Elsevier
ISBN: 0080498809
Category : Science
Languages : en
Pages : 636

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Book Description
A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level.

Methods of Randomization in Experimental Design

Methods of Randomization in Experimental Design PDF Author: Valentim R. Alferes
Publisher: SAGE
ISBN: 1452202923
Category : Psychology
Languages : en
Pages : 209

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Book Description
This text provides a conceptual systematization and a practical tool for the randomization of between-subjects and within-subjects experimental designs.

Basics of Software Engineering Experimentation

Basics of Software Engineering Experimentation PDF Author: Natalia Juristo
Publisher: Springer Science & Business Media
ISBN: 1475733046
Category : Computers
Languages : en
Pages : 405

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Book Description
Basics of Software Engineering Experimentation is a practical guide to experimentation in a field which has long been underpinned by suppositions, assumptions, speculations and beliefs. It demonstrates to software engineers how Experimental Design and Analysis can be used to validate their beliefs and ideas. The book does not assume its readers have an in-depth knowledge of mathematics, specifying the conceptual essence of the techniques to use in the design and analysis of experiments and keeping the mathematical calculations clear and simple. Basics of Software Engineering Experimentation is practically oriented and is specially written for software engineers, all the examples being based on real and fictitious software engineering experiments.

On the Design and Evaluation of Cumulus Modification Experiments

On the Design and Evaluation of Cumulus Modification Experiments PDF Author: Environmental Research Laboratories (U.S.). Weather Modification Program Office
Publisher:
ISBN:
Category : Precipitation forecasting
Languages : en
Pages : 76

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Book Description


Linear and Nonlinear Models for the Analysis of Repeated Measurements

Linear and Nonlinear Models for the Analysis of Repeated Measurements PDF Author: Edward Vonesh
Publisher: CRC Press
ISBN: 9780824782481
Category : Mathematics
Languages : en
Pages : 590

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Book Description
Integrates the latest theory, methodology and applications related to the design and analysis of repeated measurement. The text covers a broad range of topics, including the analysis of repeated measures design, general crossover designs, and linear and nonlinear regression models. It also contains a 3.5 IBM compatible disk, with software to implement immediately the techniques.

Natural Experiments in the Social Sciences

Natural Experiments in the Social Sciences PDF Author: Thad Dunning
Publisher: Cambridge University Press
ISBN: 1139560794
Category : Social Science
Languages : en
Pages : 379

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Book Description
This unique book is the first comprehensive guide to the discovery, analysis, and evaluation of natural experiments - an increasingly popular methodology in the social sciences. Thad Dunning provides an introduction to key issues in causal inference, including model specification, and emphasizes the importance of strong research design over complex statistical analysis. Surveying many examples of standard natural experiments, regression-discontinuity designs, and instrumental-variables designs, Dunning highlights both the strengths and potential weaknesses of these methods, aiding researchers in better harnessing the promise of natural experiments while avoiding the pitfalls. Dunning also demonstrates the contribution of qualitative methods to natural experiments and proposes new ways to integrate qualitative and quantitative techniques. Chapters complete with exercises and appendices covering specialized topics such as cluster-randomized natural experiments, make this an ideal teaching tool as well as a valuable book for professional researchers.

Basic Statistics and Pharmaceutical Statistical Applications, Second Edition

Basic Statistics and Pharmaceutical Statistical Applications, Second Edition PDF Author: James E. De Muth
Publisher: CRC Press
ISBN: 9780849337994
Category : Mathematics
Languages : en
Pages : 754

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Book Description
The first edition of Basic Statistics and Pharmaceutical Statistical Applications successfully provided a practical, easy-to-read, basic statistics book. This second edition not only updates the previous edition, but expands coverage in the area of biostatistics and how it relates to real-world professional practice. Taking you on a roller coaster ride through the world of statistics, Dr. De Muth clearly details the methodology necessary to summarize data and make informed decisions about observed outcomes. What's new or different in the Second Edition? New chapters cover: Measures of association primarily with nominal and ordinal data and and more than 15 tests Survival statistics including actuarial analysis and an introduction to multiple regression with survival data using proportional hazards regression An introduction to the topic of evidence-based practice with discussions of sensitivity and specificity, predictive values, and likelihood ratios Odds ratios and relative risk ratios that provide valuable information for dealing with probability, odds, and risk New sections address Power and sample size determination for two-sample Z-tests of proportions Clinical equivalence and noninferiority studies, process capability, and tolerance limits Methods for assessing repeatability and reproducibility Expanded information includes: Chi square, repeated measures designs, Latin Square designs, nine multiple comparison tests, and outlier testing Inverse prediction with linear regression, handling of multiple data points at different levels of independent variable, and assessment of parallelism of slopes for two samples Additional types of bivariate correlations and various assessments for independence and randomness More nonparametric tests including new information on post hoc comparisons for a significant Kruskal-Wallis test, the Kolmogorov-Smirnov goodness-of-fit test, and the Anderson-Darling test, as well as runs and range tests Eight new tables useful for the interpretation of some of the new inferential statistics De Muth provides concrete examples that enable you to effectively manage information in your day-to-day problem solving and reporting of findings. By avoiding heavy-duty mathematics and theory, even the mathematically challenged can benefit and increase their confidence in using statistics procedures.