Cox Proportional Hazards Models for Modeling the Time to Onset of Decompression Sickness in Hypobaric Environments PDF Download
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Author: Laura A. Thompson
Publisher:
ISBN:
Category : Atmospheric pressure
Languages : en
Pages : 52
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Book Description
Author: Laura A. Thompson
Publisher:
ISBN:
Category : Atmospheric pressure
Languages : en
Pages : 52
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Author: National Aeronautics and Space Administration (NASA)
Publisher: Createspace Independent Publishing Platform
ISBN: 9781720454083
Category :
Languages : en
Pages : 50
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Book Description
In this paper we fit Cox proportional hazards models to a subset of data from the Hypobaric Decompression Sickness Databank. The data bank contains records on the time to decompression sickness (DCS) and venous gas emboli (VGE) for over 130,000 person-exposures to high altitude in chamber tests. The subset we use contains 1,321 records, with 87% censoring, and has the most recent experimental tests on DCS made available from Johnson Space Center. We build on previous analyses of this data set by considering more expanded models and more detailed model assessments specific to the Cox model. Our model - which is stratified on the quartiles of the final ambient pressure at altitude - includes the final ambient pressure at altitude as a nonlinear continuous predictor, the computed tissue partial pressure of nitrogen at altitude, and whether exercise was done at altitude. We conduct various assessments of our model, many of which are recently developed in the statistical literature, and conclude where the model needs improvement. We consider the addition of frailties to the stratified Cox model, but found that no significant gain was attained above a model that does not include frailties. Finally, we validate some of the models that we fit.Thompson, Laura A. and Chhikara, Raj S. and Conkin, JohnnyJohnson Space CenterDECOMPRESSION SICKNESS; EXTRAVEHICULAR ACTIVITY; DATA BASES; PARTIAL PRESSURE; HIGH ALTITUDE TESTS; HAZARDS; QUARTILES; PRESSURE; PHYSICAL EXERCISE; NONLINEARITY; NITROGEN; EXPOSURE; ALTITUDE SIMULATION; AEROEMBOLISM
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1792
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Author: Michael R. Barratt
Publisher: Springer Science & Business Media
ISBN: 0387681647
Category : Medical
Languages : en
Pages : 592
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Book Description
Over the years, a large body of knowledge has developed regarding the ways in which space flight affects the health of the personnel involved. Now, for the first time, this clinical knowledge on how to diagnose and treat conditions that either develop during a mission or because of a mission has been compiled by Drs. Michael Barratt and Sam L. Pool of the NASA/Johnson Space Center. Complete with detailed information on the physiological and psychological affects of space flight as well as how to diagnose and treat everything from dental concerns to decompression to dermatological problems encountered, this text is a must have for all those associated with aerospace medicine.
Author: Linda Ed Weaver
Publisher:
ISBN: 9781930536739
Category : Medical
Languages : en
Pages : 415
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Book Description
The Undersea and Hyperbaric Medical Society (UHMS) is an international, non-profit organization serving over 2,400 members from more than 50 countries. The UHMS is the primary source of scientific information for diving and hyperbaric medicine physiology worldwide, the breadth of which is illustrated in the triennial report, Hyperbaric Oxygen Therapy Indications. With leading experts authoring chapters in their respective fields, this publication continues to provide the most current and up to date guidance and support for scientists and practitioners of hyperbaric oxygen therapy. Hyperbaric Oxygen Therapy Indications, currently in its thirteenth edition, has grown in size and depth to reflect the evolution of the literature on the approved use of hyperbarics from both a clinical practice standpoint and insurance coverage perspective. To date, the committee recognizes fourteen indications, including the new indication, idiopathic sudden sensorineural hearing loss. Additionally, this book continues to be used by the Centers for Medicare and Medicaid Services and other third party insurance carriers in determining payment for HBO2 services.
Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 2540
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Author: Richard E. Moon
Publisher:
ISBN: 9781947239166
Category : Medical
Languages : en
Pages : 0
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Book Description
Since its first appearance in 1977, the UHMS Hyperbaric Oxygen Therapy Indications has served as a guide for practitioners and scientists interested in hyperbaric and undersea medicine.
Author: Barry S. Levy
Publisher: American Public Health Association
ISBN: 9780875530437
Category : Medical
Languages : en
Pages : 628
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Book Description
Author: Thomas Reilly
Publisher: Human Kinetics
ISBN: 1492582344
Category : Science
Languages : en
Pages : 414
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Book Description
Ergonomics in Sport and Physical Activity: Enhancing Performance and Improving Safety is also available as an e-book. The e-book is available at a reduced price and allows readers to highlight and take notes throughout the text. When purchased through the Human Kinetics site, access to the e-book is immediately granted when the order is received.Ergonomics in Sport and Physical Activity: Enhancing Performance and Improving Safety is the first text to provide an in-depth discussion of how the principles of ergonomics can be applied in the context of sport and other physical activities to reduce injury and improve performance. The textblends concepts from biomechanics, physiology, and psychology as it shows how ergonomics is applied to physical activity. This comprehensive text outlines methods for assessing risk in and procedures for dealing with stress, eliminating hazards, and evaluating challenges posed in specific work or sport environments. It discusses issues such as the design of effective equipment, clothing, and playing surfaces; methods of assessing risk in situations; and staying within appropriate training levels to reduce fatigue and avoid overtraining. The text not only examines sport ergonomics but also discusses ergonomic considerations for physically active special populations. Ergonomics in Sport and Physical Activity explains what ergonomics is, how ergonomists solve practical problems in the workplace, and how principles of ergonomics are applied in the context of sport and other physical activities when solving practical problems related to human characteristics and capabilities. The text shows readers how to improve performance, achieve optimal efficiency, enhance comfort, and reduce injuries by exploring topics such as these: Essential concepts, terms, and principles of ergonomics and how these relate to physical activity Physical properties of the body and the factors limiting performance Interactions between the individual, the task, and the environment Injury risk factors in relation to body mechanics in various physical activities Injury prevention and individual protection in the review of sports equipment and sports environments Comfort, efficiency, safety, and details of systems criteria in equipment design This research-based text uses numerous practical examples, figures, charts, and graphs to bring the material to life. In addition, descriptions of technological advances show where we have been and how technology has advanced the field. Through the book’s discussion of the various stressors and adaptive mechanisms, readers will learn how to cope with various environmental conditions. They will also learn how various training modes can be used to alter sport-specific capabilities and enhance performance. Presenting a wide range of approaches, theoretical models, and analytical techniques, Ergonomics in Sport and Physical Activity: Enhancing Performance and Improving Safety illustrates the potential for ergonomics to be extended across recreation, competitive sport, and physically active work environments. Bridging the gap between ergonomics and exercise science, this unique text will assist both health care and exercise professionals in developing an improved awareness of how human capabilities are best matched to physical activities.
Author: Jun Chen
Publisher: Springer Science & Business Media
ISBN: 1603271856
Category : Medical
Languages : en
Pages : 490
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Book Description
Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.
