CONTRIBUTION OF BLOOD BIOMARKERS TO THE DIAGNOSIS OF CARDIOEMBOLIC STROKE PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download CONTRIBUTION OF BLOOD BIOMARKERS TO THE DIAGNOSIS OF CARDIOEMBOLIC STROKE PDF full book. Access full book title CONTRIBUTION OF BLOOD BIOMARKERS TO THE DIAGNOSIS OF CARDIOEMBOLIC STROKE by Markus Kneihsl. Download full books in PDF and EPUB format.
Author: Markus Kneihsl
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Background and purpose:Cardioembolic strokes can be effectively prevented by anticoagulation1. Blood biomarkers helping to suggest cardioembolic etiology and to steer the complex diagnostic work-up would therefore be of great advantage2. This study addresses the possible contribution of biomarkers associated with heart failure (NT-proBNP) and thromboembolism (D-dimer) to the diagnosis of cardioembolic stroke.Methods:Over a seven months period, we prospectively investigated all ischemic stroke patients admitted to our Stroke Unit for this study. All patients underwent a complete stroke work-up including cerebral imaging (CT and/or MRI), neurosonography, electrocardiography, cardiac rhythm monitoring (for at least 24 hours) and echocardiography. Blood to determine NT-proBNP and D-dimer levels was drawn within 24 hours after admission.Results:Of 188 ischemic stroke patients (age: 69u00b114 years, female: 38%), 67 had cardioembolic (36%), 73 non-cardioembolic (49%) and 48 cryptogenic strokes (25%), based on extensive work-up. NT-proBNP and D-dimer levels were significantly higher in cardioembolic vs. non-cardioembolic strokes (2543 vs. 707 pg/ml, p
Author: Markus Kneihsl
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Background and purpose:Cardioembolic strokes can be effectively prevented by anticoagulation1. Blood biomarkers helping to suggest cardioembolic etiology and to steer the complex diagnostic work-up would therefore be of great advantage2. This study addresses the possible contribution of biomarkers associated with heart failure (NT-proBNP) and thromboembolism (D-dimer) to the diagnosis of cardioembolic stroke.Methods:Over a seven months period, we prospectively investigated all ischemic stroke patients admitted to our Stroke Unit for this study. All patients underwent a complete stroke work-up including cerebral imaging (CT and/or MRI), neurosonography, electrocardiography, cardiac rhythm monitoring (for at least 24 hours) and echocardiography. Blood to determine NT-proBNP and D-dimer levels was drawn within 24 hours after admission.Results:Of 188 ischemic stroke patients (age: 69u00b114 years, female: 38%), 67 had cardioembolic (36%), 73 non-cardioembolic (49%) and 48 cryptogenic strokes (25%), based on extensive work-up. NT-proBNP and D-dimer levels were significantly higher in cardioembolic vs. non-cardioembolic strokes (2543 vs. 707 pg/ml, p
Author: Philip V. Peplow
Publisher: Humana
ISBN: 9781493996810
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This volume presents the latest data on recent achievements in new and emerging technologies for stroke biomarkers and innovations in stroke assessment. The topics discussed in this book explore the role of upcoming biomarkers in different types of stroke, and explores techniques that will allow researchers to be more effective when approaching clinical management and patient care. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to ensure successful results in the laboratory. Cutting-edge and comprehensive, Stroke Biomarkers is a valuable resource for both experimental and clinical scientists interested in expanding their knowledge in the field of stroke research.
Author: Ana Catarina Fonseca
Publisher: Springer
ISBN: 9783030707637
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this area. Precision Medicine in Stroke provides a practical approach to each chapter, reinforcing clinical applications and presenting clinical cases. This book is intended for all clinicians that interact with stroke patients (neurologists, internal medicine doctors, general practitioners, neurosurgeons), students and basic researchers.
Author: Julien Bogousslavsky
Publisher: CRC Press
ISBN: 9781853174131
Category : Medical
Languages : en
Pages : 320
Get Book Here
Book Description
Owing to the increased interest in brain ischemia and the new therapeutic options from pharmaceutical companies for the treatment of acute stroke, Professor Julien Bogousslavsky, one of the world's stroke experts, has revised his best-selling book. It is the emergence of huge possibilities in the management of stroke - ultra-early diagnosis, intensive care, surgical and other interventional therapies, thrombolysis, anti-ischemic drugs and prevention of immediate recurrence - which necessiates this timely update.
Author: Ulrich Dirnagl
Publisher: Springer Science & Business Media
ISBN: 3662054264
Category : Medical
Languages : en
Pages : 248
Get Book Here
Book Description
The successful treatment of acute stroke remains one of the major challenges in clinical medicine. Over the last decades, the understanding of stroke pathophysiology has greatly improved, while the therapeutic options in stroke therapy remain very limited. Today, hyperacute mechanisms of damage, such as excitotoxicity, can be discriminated from delayed ones, such as inflammation and apoptosis. Targeting of inflammation has already been successfully applied in various stroke models, but translation into a clinically efficacious strategy has not been achieved so far. In this book, leading experts in basic cerebrovascular research as well as stroke treatment review the current evidence for and against an important role for inflammation in stroke, and explore the potential of treating or modulating inflammation in stroke therapy.
Author: Bruce Ovbiagele
Publisher: Springer
ISBN: 3319177508
Category : Medical
Languages : en
Pages : 321
Get Book Here
Book Description
This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all over the world and feature the scientific evidence behind prevailing therapeutic strategies for managing ischemic cerebrovascular disease. The specialist or general practitioner will gain critical knowledge in stroke management, current clinical challenges and promising new therapies under investigation.
Author: Robert G. Kowalski
Publisher: Frontiers Media SA
ISBN: 2889745449
Category : Medical
Languages : en
Pages : 348
Get Book Here
Book Description
Topic Editor, Prof. Heinrich Audebert, received funding from institutional funding by Roche Diagnostics International Ltd. and the Berlin Future Funds. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Author: Hugh S. Markus
Publisher: Oxford Medical Publications
ISBN: 0198515863
Category : Medical
Languages : en
Pages : 362
Get Book Here
Book Description
Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.
Author: John W. Norris
Publisher: Springer Science & Business Media
ISBN: 1475742266
Category : Medical
Languages : en
Pages : 280
Get Book Here
Book Description
Prevention of Stroke sums up and critically analyzes our present knowledge and understanding of all major aspects of stroke prophylaxis, medical and surgical. The book is intended for not only neurologists and neurosurgeons directly involved with stroke patients, but also vascular surgeons, internists, family physicians, and health planners. Topics explored include the cellular basis of atherosclerosis; stroke risk factors; head and neck bruits in stroke prevention; the present status of anticoagulant prophylaxis; hypertension and stroke prevention; and prevention of cardioembolic stroke, as well as the efficacy of aspirin and of ticlopidine in stroke prevention. Surgical prophylaxis is examined through discussions of carotid endarterectomy, prevention of stroke from cerebral vascular malformations, prevention of aneurysmal subarachnoid hemorrhage, balloon transluminal angioplasty of the carotid artery in the head and neck, and prevention of recurrent stroke.
Author: Jens Minnerup
Publisher: Biota Publishing
ISBN: 1615045872
Category : Science
Languages : en
Pages : 102
Get Book Here
Book Description
Stroke is a major global health problem because of its large contribution to mortality, morbidity, and disability. The most common form of stroke is ischemic stroke which accounts for approximately 80% of all strokes. During the past decade, our knowledge of the molecular and cellular processes that contribute to stroke pathophysiology has increased substantially and offers many targets for future therapeutic strategies. This book provides an overview of the current knowledge of stroke pathophysiology and the mechanisms that interfere with recovery and regeneration. Moreover, this book reviews the latest advances in the development of future therapeutic strategies.
