Connectivity and Functional Organization in the Mammalian Visual Cortex PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Connectivity and Functional Organization in the Mammalian Visual Cortex PDF full book. Access full book title Connectivity and Functional Organization in the Mammalian Visual Cortex by Daniel Yue-Yun Ts'o. Download full books in PDF and EPUB format.
Author: Daniel Yue-Yun Ts'o
Publisher:
ISBN:
Category : Mammals
Languages : en
Pages : 140
Get Book Here
Book Description
Author: Daniel Yue-Yun Ts'o
Publisher:
ISBN:
Category : Mammals
Languages : en
Pages : 140
Get Book Here
Book Description
Author: Lee Cossell
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 282
Get Book Here
Book Description
Author: Estela V. O'Brien
Publisher:
ISBN:
Category :
Languages : en
Pages : 168
Get Book Here
Book Description
Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173
Get Book Here
Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Author: Balazs Gulyas
Publisher: Elsevier Health Sciences
ISBN: 1483287785
Category : Medical
Languages : en
Pages : 408
Get Book Here
Book Description
Functional Organisation of the Human Visual Cortex
Author: WHITE
Publisher: Springer Science & Business Media
ISBN: 1468487213
Category : Medical
Languages : en
Pages : 299
Get Book Here
Book Description
This elegant book presents current evidence on the organization of the mammalian cerebral cortex. The focus on synapses and their function provides the basis for understanding how this critical part of the brain could work. Dr. White and his colleague Dr. Keller have collated an impressive mass of material. This makes the crucial information accessible and coherent. Dr. White pioneered an area of investigation that to most others, and occasionally to himself, seemed a bottomless pit of painstaking at tention to detail for the identification and enumeration of cortical syn apses. I do not recall that he or anyone else suspected, when he began to publish his now classic papers, that the work would be central to an accelerating convergence of information and ideas from neurobiology and computer science, especially artificial intelligence (AI) (Rumelhart and McClelland, 1986). The brain is the principal organ responsible for the adaptive capacities of animals. What has impressed students of biology, of medicine, and, to an extent, of philosophy is the correlation between the prominence of the cerebral cortex and the adaptive "complexity" of a particular spe cies. Most agree that the cortex is what sets Homo sapiens apart from other species quantitatively and qualitatively (Rakic, 1988). This is summarized in the first chapter.
Author: Helga Kolb
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Adrian K. Andelin
Publisher:
ISBN:
Category :
Languages : en
Pages : 158
Get Book Here
Book Description
Despite the fact that the visual system has been the most well-studied of all sensory systems, many questions remain in regard to its structure and function in both human and animal models. While a basic blueprint of the visual system exists across all animal species that sets in place the basic structure prior to the onset of visual experience, it has been well established that this system becomes fine-tuned through experience early in life. Using a variety of techniques and animal models, this dissertation addresses some questions regarding the functional organization and the effect of visual deprivation on the visual cortex of several animal models. Rodents offer several advantages for studying various aspects of the development, organization and plasticity of the visual system. An important model for studies of visual cortex plasticity is the system of ocular dominance columns (ODC, aggregates of cells with the same eye preference), which have been extensively studied in many carnivores and primates, but have been thought not to exist in rodents. Our lab recently reported the existence of ODCs in pigmented, Long Evans rats (Laing et al. 2015), but previous reports in albino rats (Diao et al., 1983) point to differences in the binocularity of certain regions of primary visual cortex (V1) and in the role that callosal connections may have in these differences. To explain these strain differences, we hypothesized that albino rats, unlike Long Evans rats, do not have ODCs, and that callosal connections in V1 of albino rats are not patchy, as they are in Long Evans rats. In the first chapter of this dissertation, we present anatomical and electrophysiological experiments supporting our prediction that input from both eyes intermix in the binocular region of V1 in albino rats, without segregating into ODCs, and that callosal connections in albino rats are homogeneously distributed in V1. In the second chapter, we explore the effect of loss of vision during early development on the surface area of V1. Using histological methods as well as MRI techniques, we examined how the reduction in mature brain surface area varies with age when blindness occurs in rats, ferrets and humans. To compare data across species, we translated the post-conception ages of each species to a common neurodevelopmental event-time scale. We predicted that the critical period for the effect of blindness on the area of V1 ends at a common developmental event-time across species. Our results support our prediction, and also show that the critical period for the effect of blindness on V1 surface area ends well before the visual cortex reaches its normal, mature size. Much of the research on the organization and function of visual cortex is presently carried out in mice. While a present advantage of mice is the possibility of using genetic tools, a disadvantage is the small size of their brain and visual cortex. In the third chapter, we use multiple anatomical tracers to explore the number, arrangement and internal topographic organization of extrastriate visual areas in the rabbit, whose brain is about 60 times larger than the mouse brain. Our results show that the visual cortical plan in rabbits closely resembles the plan in mice and rats, suggesting that the rodent plan may be more general, encompassing Lagomorphs and possibly other orders. Our study also underscores the usefulness of the rabbit as an alternative model to rats and mice for projects benefiting from a larger brain.
Author: David C. Van Essen
Publisher:
ISBN:
Category :
Languages : en
Pages : 26
Get Book Here
Book Description
This report used a combination of physiological and anatomical approaches to elucidate the functional organization of visual cortex in the macaque monkey. One project was a single cell analysis of texture vision, using texture patterns of the type developed by Julesz for human psychophysical studies. Many cells tested in area V2 responded to static or moving texture gradients in ways which were not predictable on the basis of responses to individual texture elements and which correlated with the preattentive discriminability of these texture patterns to human observers. A second project involved the development of a computerized technique for generating two-dimensional maps of cerebral cortex. An algorithm based on simulated annealing procedures was used to construct a complete map of primary visual cortex, thereby demonstrating its suitability for dealing with anatomical data from highly convoluted regions of cortex. A third project involved the use of voltage-sensitive dyes to monitor activity patterns in visual cortex. This technique offers great promise for analyzing the organization of large neural ensembles with high spatial and temporal resolution. Keywords: Cerebral cortex; Pattern recognition; Cortical mapping; Single neuron physiology.
