Circular Dichroism and the Conformational Analysis of Biomolecules

Circular Dichroism and the Conformational Analysis of Biomolecules PDF Author: G.D. Fasman
Publisher: Springer Science & Business Media
ISBN: 1475725086
Category : Science
Languages : en
Pages : 739

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Book Description
''Excellent and very timely....It will undoubtedly become a standard reference for the application of circular dichroism (CD) to biomolecules.'' --- Quarterly Review of Biology, March 1997 ''[T]estament to the book's utility is the fact that during the course of my review I had to 'rescue' it from the desks of graduate students on an almost daily basis. In summary, this is a great book.'' --- American Scientist ''Well documented chapters provide a very good insight into the problems surrounding the conformation of biomacromolecules...An indispensible source of information.'' --- Nahrung, 42(2), 1998 Renowned experts present the first state-of-the-art description of circular dichroism spectroscopy (CD). Chapters present in-depth discussions of the history of the field, the theory of CD for application to globular proteins, membrane proteins, peptides, nucleic acids and their interactions, carbohydrates, and instrumentation. Discussions also feature new techniques using synchrotron radiation, vibrational Raman optical activity, and vibrational CD. More than 250 illustrations supplement the text.

Circular Dichroism and the Conformational Analysis of Biomolecules

Circular Dichroism and the Conformational Analysis of Biomolecules PDF Author: G.D. Fasman
Publisher: Springer Science & Business Media
ISBN: 1475725086
Category : Science
Languages : en
Pages : 739

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Book Description
''Excellent and very timely....It will undoubtedly become a standard reference for the application of circular dichroism (CD) to biomolecules.'' --- Quarterly Review of Biology, March 1997 ''[T]estament to the book's utility is the fact that during the course of my review I had to 'rescue' it from the desks of graduate students on an almost daily basis. In summary, this is a great book.'' --- American Scientist ''Well documented chapters provide a very good insight into the problems surrounding the conformation of biomacromolecules...An indispensible source of information.'' --- Nahrung, 42(2), 1998 Renowned experts present the first state-of-the-art description of circular dichroism spectroscopy (CD). Chapters present in-depth discussions of the history of the field, the theory of CD for application to globular proteins, membrane proteins, peptides, nucleic acids and their interactions, carbohydrates, and instrumentation. Discussions also feature new techniques using synchrotron radiation, vibrational Raman optical activity, and vibrational CD. More than 250 illustrations supplement the text.

Conformational Analysis

Conformational Analysis PDF Author: Ernest Ludwig Eliel
Publisher:
ISBN:
Category : Conformational analysis
Languages : en
Pages : 0

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Book Description


Organic Conformational Analysis and Stereochemistry from Circular Dichroism Spectroscopy

Organic Conformational Analysis and Stereochemistry from Circular Dichroism Spectroscopy PDF Author: David A. Lightner
Publisher: John Wiley & Sons
ISBN: 9780471354055
Category : Science
Languages : en
Pages : 508

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Book Description
Unter Zirkulardichroismus (CD) versteht man die spezifisch unterschiedliche Absorption von links- und rechtszirkular polarisiertem Licht durch bestimmte Moleküle. CD-Effekte lassen sich in Abhängigkeit von der Wellenlänge messen und spektroskopisch auswerten; sie geben beispielsweise Auskunft über die Konformation organischer Verbindungen. Dieses Buch richtet sich an den organischen Chemiker, der mit den Grundprinzipien der Stereochemie vertraut ist, und erläutert die Anwendung der CD-Spektroskopie zur Konformationsanalyse ausführlich und verständlich. (06/00)

Conformational Analysis

Conformational Analysis PDF Author: G Chiurdoglu
Publisher: Elsevier
ISBN: 0323157319
Category : Science
Languages : en
Pages : 293

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Book Description
Conformational Analysis: Scope and Present Limitations contains the proceedings of the Brussels International Symposium on Conformational Analysis held in Brussels, Belgium, in September 1969. The papers focus on the theoretical aspects and applications of conformational analysis, such as those concerning the aliphatic and especially the cyclic series. Topics covered include the geometry of five-membered rings; conformational transmission in steroids; conformational aspects of N-quaternization; and applications of nuclear magnetic resonance spectrometry in conformational studies of cyclohexane derivatives. This book is comprised of 20 chapters and begins with a discussion on the conformational aspects of some five-membered ring compounds based mainly on observed (diffraction methods) and calculated torsional angles. The reader is then introduced to nuclear magnetic resonance studies of the conformations and conformational barriers in cyclic molecules; conformational studies of six-membered heterocycles; conformational transmission in steroids; and solvolytic cyclizations involving double bonds. The remaining chapters explore the conformational analysis of methylcyclohexane, cyclohexane systems, and carbonium ions; conformations of membrane-active cyclodepsipeptides; energetics of isomeric transition states and competitive reaction pathways in conformational analysis; and conformational aspects of the reaction of the 1-methylcyclodecane-l,6-diols with acid. This monograph will be of interest to organic chemists.

Principles of Conformation Analysis: Equus Reference Guide

Principles of Conformation Analysis: Equus Reference Guide PDF Author: Deb Bennett
Publisher: Trafalgar Square Publishing
ISBN: 9781929164608
Category : Nature
Languages : en
Pages : 300

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Book Description
Everything you need to know about horse anatomy is found here. Follow expert Dr. Deb Bennett as she takes an in-depth, informed look at conformation and reveals how to improve your performance and harmony with your horse. The three popular volumes of Principles of Conformation Analysis are now available in this one edition, providing the most comprehensive insight into equine structure and its effects on movement, soundness, and performance. Within these pages, you'll find: * Valuable guidelines for examining the suitability of horses for various activities * Hundreds of photos, charts, and drawings explaining various body parts and the way they work together * Detailed information on how to minimize conformational limitations and maximize your horse's performance, whatever his breed or sport * Simple methods for analyzing hind legs and detecting horses with lame backs * Exclusive lab exercises from Dr. Deb's files that offer practical help in evaluating your own horse Whether you're looking for an international dressage horse or a comfortable pleasure mount, Principles of Conformation Analysis will improve your eye for conformation.And no matter how you're involved in the horse industry--as a buyer, trainer, rider, or breeder--this book will enrich your equestrian experience.

Modern Conformational Analysis

Modern Conformational Analysis PDF Author: Helena Dodziuk
Publisher: John Wiley & Sons
ISBN: 9780471186113
Category : Science
Languages : en
Pages : 280

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Book Description
Viele Bücher über organische Zusammensetzungen behandeln die Stereochemie, schenken aber der räumlichen Struktur der organischen Moleküle, vor allem der weniger gebräuchlichen, kaum Beachtung. Diese Monographie stellt nun ein umfassendes Werk zur organischen Struktur und der Konformationsanalyse dar. Das Interesse des Autors an der Formenvielfalt der organischen Moleküle spiegelt sich besonders intensiv in der Betrachtung der Molekülordnung wider, die in organisch chemischen und biologischen Systemen von großer Bedeutung ist. Der neue Band in der Reihe 'Methods in Stereochemical Analysis' stellt vor allem diese Bedeutung der Molekülgestalt und die Einwirkung theoretischer Studien und synthetischer Chemie zu diesem Themenkomplex in den Vordergrund.

Potential Energy Functions in Conformational Analysis

Potential Energy Functions in Conformational Analysis PDF Author: Kjeld Rasmussen
Publisher: Springer Science & Business Media
ISBN: 3642455913
Category : Science
Languages : en
Pages : 241

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Book Description
I get by with a little help from my friends The Beatles: Sgt. Pepper This book should have been in Danish. Any decent person must be able to express himself in his mother's tongue, also when expounding scientific ideas and results. Had I stuck to this ideal, the book would have been read by very few people, and, indeed, appreciated by even fewer. Having it publ ished in English gives me a chance to fulfill one ambition: to be read and judged by the international scientific community. Another reason is that the majority of my professional friends are regrettably unread in Danish, just as I am in Hebrew, Finnish and even Italian. I want to deprive them of the most obvious excuse for not reading my opus. Like a man I admired, I will first of all thank my wife. In his autobiography, Meir Weisgal, then President of the Weizmann Insti tute of SCience, wrote about his wife: "In addition to her natural endowments - which are considerable - she was a more than competent part-tim~ secretary." He wrote on, and so shall I. The book has been edited by my wife. So if the reader finds the layout pleasant as, in actual fact, I myself do, Birgit is to be praised. If there are blemishes, I am to be blamed for not having caught them.

AMolecular Description of Biological Membrane Components by Computer Aided Conformational Analysis

AMolecular Description of Biological Membrane Components by Computer Aided Conformational Analysis PDF Author: Robert Brasseur
Publisher: CRC Press
ISBN: 1000697665
Category : Medical
Languages : en
Pages : 444

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Book Description
First published in 1990, the goal of these two volumes is to help fill the gap between theory and experiment in membrane science. Those involved with biochemistry, biophysics, pharmacology, and biology will find these volumes interesting and informative.

Molecular Description of Biological Membrane Components by Computer Aided Conformational Analysis

Molecular Description of Biological Membrane Components by Computer Aided Conformational Analysis PDF Author: Robert Brasseur
Publisher: CRC Press
ISBN: 9780849363764
Category : Medical
Languages : en
Pages : 236

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Book Description
The goal of these two volumes is to help fill the gap between theory and experiment in membrane science. This is the only work available today which covers the domain of computer-aided conformational analyses of membranes. Written in a detailed, yet comprehensive manner, this book uses the semi-empirical approach as a way to give a molecular description of the membrane structure in organized systems. This interesting work establishes the validity and quality of the prediction by making a permanent comparison with the experimental data. This reference aims to use this comparison to open a new avenue in the molecular description of the biological membrane. Those involved with biochemistry, biophysics, pharmacology, and biology will find these volumes interesting and informative.

Approaches to the Conformational Analysis of Biopharmaceuticals

Approaches to the Conformational Analysis of Biopharmaceuticals PDF Author: Roger L. Lundblad
Publisher: CRC Press
ISBN: 1439807817
Category : Medical
Languages : en
Pages : 370

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Book Description
The activity of many biopharmaceutical polymers is dependent on conformation, and the next several years will see increased interest in the conformational analysis of these polymers resulting from the development of biosimilar or "follow-on" biological products. While a wide variety of approaches to analysis exists, finding the most viable ones wou