Computational Methods in Biomedical Research

Computational Methods in Biomedical Research PDF Author: Ravindra Khattree
Publisher: CRC Press
ISBN: 9781420010923
Category : Mathematics
Languages : en
Pages : 432

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Book Description
Continuing advances in biomedical research and statistical methods call for a constant stream of updated, cohesive accounts of new developments so that the methodologies can be properly implemented in the biomedical field. Responding to this need, Computational Methods in Biomedical Research explores important current and emerging computational statistical methods that are used in biomedical research. Written by active researchers in the field, this authoritative collection covers a wide range of topics. It introduces each topic at a basic level, before moving on to more advanced discussions of applications. The book begins with microarray data analysis, machine learning techniques, and mass spectrometry-based protein profiling. It then uses state space models to predict US cancer mortality rates and provides an overview of the application of multistate models in analyzing multiple failure times. The book also describes various Bayesian techniques, the sequential monitoring of randomization tests, mixed-effects models, and the classification rules for repeated measures data. The volume concludes with estimation methods for analyzing longitudinal data. Supplying the knowledge necessary to perform sophisticated statistical analyses, this reference is a must-have for anyone involved in advanced biomedical and pharmaceutical research. It will help in the quest to identify potential new drugs for the treatment of a variety of diseases.

Computational Methods in Biomedical Research

Computational Methods in Biomedical Research PDF Author: Ravindra Khattree
Publisher: CRC Press
ISBN: 9781420010923
Category : Mathematics
Languages : en
Pages : 432

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Book Description
Continuing advances in biomedical research and statistical methods call for a constant stream of updated, cohesive accounts of new developments so that the methodologies can be properly implemented in the biomedical field. Responding to this need, Computational Methods in Biomedical Research explores important current and emerging computational statistical methods that are used in biomedical research. Written by active researchers in the field, this authoritative collection covers a wide range of topics. It introduces each topic at a basic level, before moving on to more advanced discussions of applications. The book begins with microarray data analysis, machine learning techniques, and mass spectrometry-based protein profiling. It then uses state space models to predict US cancer mortality rates and provides an overview of the application of multistate models in analyzing multiple failure times. The book also describes various Bayesian techniques, the sequential monitoring of randomization tests, mixed-effects models, and the classification rules for repeated measures data. The volume concludes with estimation methods for analyzing longitudinal data. Supplying the knowledge necessary to perform sophisticated statistical analyses, this reference is a must-have for anyone involved in advanced biomedical and pharmaceutical research. It will help in the quest to identify potential new drugs for the treatment of a variety of diseases.

Computer Methods in Biomechanics and Biomedical Engineering 2

Computer Methods in Biomechanics and Biomedical Engineering 2 PDF Author: J. Middleton
Publisher: CRC Press
ISBN: 1000159450
Category : Medical
Languages : en
Pages : 856

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Book Description
Contains papers presented at the Third International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (1997), which provide evidence that computer-based models, and in particular numerical methods, are becoming essential tools for the solution of many problems encountered in the field of biomedical engineering. The range of subject areas presented include the modeling of hip and knee joint replacements, assessment of fatigue damage in cemented hip prostheses, nonlinear analysis of hard and soft tissue, methods for the simulation of bone adaptation, bone reconstruction using implants, and computational techniques to model human impact. Computer Methods in Biomechanics and Biomedical Engineering also details the application of numerical techniques applied to orthodontic treatment together with introducing new methods for modeling and assessing the behavior of dental implants, adhesives, and restorations. For more information, visit the "http://www.uwcm.ac.uk/biorome/international symposium on Computer Methods in Biomechanics and Biomedical Engineering/home page, or "http://www.gbhap.com/Computer_Methods_Biomechanic s_Biome dical_Engineering/" the home page for the journal.

Numerical Methods in Biomedical Engineering

Numerical Methods in Biomedical Engineering PDF Author: Stanley Dunn
Publisher: Elsevier
ISBN: 0080470807
Category : Science
Languages : en
Pages : 628

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Book Description
Numerical Modeling in Biomedical Engineering brings together the integrative set of computational problem solving tools important to biomedical engineers. Through the use of comprehensive homework exercises, relevant examples and extensive case studies, this book integrates principles and techniques of numerical analysis. Covering biomechanical phenomena and physiologic, cell and molecular systems, this is an essential tool for students and all those studying biomedical transport, biomedical thermodynamics & kinetics and biomechanics. - Supported by Whitaker Foundation Teaching Materials Program; ABET-oriented pedagogical layout - Extensive hands-on homework exercises

Essential Numerical Computer Methods

Essential Numerical Computer Methods PDF Author: Michael L. Johnson
Publisher: Academic Press
ISBN: 0123849985
Category : Mathematics
Languages : en
Pages : 647

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Book Description
The use of computers and computational methods has become ubiquitous in biological and biomedical research. During the last 2 decades most basic algorithms have not changed, but what has is the huge increase in computer speed and ease of use, along with the corresponding orders of magnitude decrease in cost. A general perception exists that the only applications of computers and computer methods in biological and biomedical research are either basic statistical analysis or the searching of DNA sequence data bases. While these are important applications they only scratch the surface of the current and potential applications of computers and computer methods in biomedical research. The various chapters within this volume include a wide variety of applications that extend far beyond this limited perception. As part of the Reliable Lab Solutions series, Essential Numerical Computer Methods brings together chapters from volumes 210, 240, 321, 383, 384, 454, and 467 of Methods in Enzymology. These chapters provide a general progression from basic numerical methods to more specific biochemical and biomedical applications. - The various chapters within this volume include a wide variety of applications that extend far beyond this limited perception - As part of the Reliable Lab Solutions series, Essential Numerical Computer Methods brings together chapters from volumes 210, 240, 321, 383, 384, 454, and 467 of Methods in Enzymology - These chapters provide a general progression from basic numerical methods to more specific biochemical and biomedical applications

Bayesian Computational Methods in Biomedical Research

Bayesian Computational Methods in Biomedical Research PDF Author: Hedibert Freitas Lopes
Publisher:
ISBN:
Category : Mathematical statistics
Languages : en
Pages : 77

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Book Description


Advances in Computational Techniques for Biomedical Image Analysis

Advances in Computational Techniques for Biomedical Image Analysis PDF Author: Deepika Koundal
Publisher: Academic Press
ISBN: 0128204117
Category : Computers
Languages : en
Pages : 324

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Book Description
Advances in Computational Techniques for Biomedical Image Analysis: Methods and Applications focuses on post-acquisition challenges such as image enhancement, detection of edges and objects, analysis of shape, quantification of texture and sharpness, and pattern analysis. It discusses the archiving and transfer of images, presents a selection of techniques for the enhancement of contrast and edges, for noise reduction and for edge-preserving smoothing. It examines various feature detection and segmentation techniques, together with methods for computing a registration or normalization transformation. Advances in Computational Techniques for Biomedical Image Analysis: Method and Applications is ideal for researchers and post graduate students developing systems and tools for health-care systems. - Covers various challenges and common research issues related to biomedical image analysis - Describes advanced computational approaches for biomedical image analysis - Shows how algorithms are applied to a broad range of application areas, including Chest X-ray, breast CAD, lung and chest, microscopy and pathology, etc. - Explores a range of computational algorithms and techniques, such as neural networks, fuzzy sets, and evolutionary optimization - Explores cloud based medical imaging together with medical imaging security and forensics

New Developments on Computational Methods and Imaging in Biomechanics and Biomedical Engineering

New Developments on Computational Methods and Imaging in Biomechanics and Biomedical Engineering PDF Author: João Manuel R. S. Tavares
Publisher: Springer
ISBN: 3030230732
Category : Medical
Languages : en
Pages : 160

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Book Description
This book gathers selected, extended and revised contributions to the 15th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE2018), and the 3rd Conference on Imaging and Visualization, which took place on 26-29 March, 2018, in Lisbon, Portugal. The respective chapters highlight cutting-edge methods, e.g. new algorithms, image analysis techniques, and multibody modeling methods; and new findings obtained by applying them in biological and/or medical contexts. Original numerical studies, Monte Carlo simulations, FEM analyses and reaction-diffusion models are described in detail, together with intriguing new applications. The book offers a timely source of information for biologists, engineers, applied mathematicians and clinical researchers working on multidisciplinary projects, and is also intended to foster closer collaboration between these groups.

Methods in Biomedical Informatics

Methods in Biomedical Informatics PDF Author: Indra Neil Sarkar
Publisher: Academic Press
ISBN: 0124016847
Category : Computers
Languages : en
Pages : 589

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Book Description
Beginning with a survey of fundamental concepts associated with data integration, knowledge representation, and hypothesis generation from heterogeneous data sets, Methods in Biomedical Informatics provides a practical survey of methodologies used in biological, clinical, and public health contexts. These concepts provide the foundation for more advanced topics like information retrieval, natural language processing, Bayesian modeling, and learning classifier systems. The survey of topics then concludes with an exposition of essential methods associated with engineering, personalized medicine, and linking of genomic and clinical data. Within an overall context of the scientific method, Methods in Biomedical Informatics provides a practical coverage of topics that is specifically designed for: (1) domain experts seeking an understanding of biomedical informatics approaches for addressing specific methodological needs; or (2) biomedical informaticians seeking an approachable overview of methodologies that can be used in scenarios germane to biomedical research. - Contributors represent leading biomedical informatics experts: individuals who have demonstrated effective use of biomedical informatics methodologies in the real-world, high-quality biomedical applications - Material is presented as a balance between foundational coverage of core topics in biomedical informatics with practical "in-the-trenches" scenarios. - Contains appendices that function as primers on: (1) Unix; (2) Ruby; (3) Databases; and (4) Web Services.

Computational Structural Biology

Computational Structural Biology PDF Author: Torsten Schwede
Publisher: World Scientific
ISBN: 9812778780
Category : Science
Languages : en
Pages : 790

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Book Description
This is a comprehensive introduction to Landau-Lifshitz equations and Landau-Lifshitz-Maxwell equations, beginning with the work by Yulin Zhou and Boling Guo in the early 1980s and including most of the work done by this Chinese group led by Zhou and Guo since. The book focuses on aspects such as the existence of weak solutions in multi dimensions, existence and uniqueness of smooth solutions in one dimension, relations with harmonic map heat flows, partial regularity and long time behaviors. The book is a valuable reference book for those who are interested in partial differential equations, geometric analysis and mathematical physics. It may also be used as an advanced textbook by graduate students in these fields.

Complex Systems Science in Biomedicine

Complex Systems Science in Biomedicine PDF Author: Thomas Deisboeck
Publisher: Springer Science & Business Media
ISBN: 0387335323
Category : Medical
Languages : en
Pages : 857

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Book Description
Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.