Computational Methods for Understanding Complexity: The Use of Formal Methods in Biology

Computational Methods for Understanding Complexity: The Use of Formal Methods in Biology PDF Author: David A. Rosenblueth,
Publisher: Frontiers Media SA
ISBN: 2889450422
Category :
Languages : en
Pages : 115

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Book Description
The complexity of living organisms surpasses our unaided habilities of analysis. Hence, computational and mathematical methods are necessary for increasing our understanding of biological systems. At the same time, there has been a phenomenal recent progress allowing the application of novel formal methods to new domains. This progress has spurred a conspicuous optimism in computational biology. This optimism, in turn, has promoted a rapid increase in collaboration between specialists of biology with specialists of computer science. Through sheer complexity, however, many important biological problems are at present intractable, and it is not clear whether we will ever be able to solve such problems. We are in the process of learning what kind of model and what kind of analysis and synthesis techniques to use for a particular problem. Some existing formalisms have been readily used in biological problems, others have been adapted to biological needs, and still others have been especially developed for biological systems. This Research Topic has examples of cases (1) employing existing methods, (2) adapting methods to biology, and (3) developing new methods. We can also see discrete and Boolean models, and the use of both simulators and model checkers. Synthesis is exemplified by manual and by machine-learning methods. We hope that the articles collected in this Research Topic will stimulate new research.

Computational Methods for Understanding Complexity: The Use of Formal Methods in Biology

Computational Methods for Understanding Complexity: The Use of Formal Methods in Biology PDF Author: David A. Rosenblueth,
Publisher: Frontiers Media SA
ISBN: 2889450422
Category :
Languages : en
Pages : 115

Get Book Here

Book Description
The complexity of living organisms surpasses our unaided habilities of analysis. Hence, computational and mathematical methods are necessary for increasing our understanding of biological systems. At the same time, there has been a phenomenal recent progress allowing the application of novel formal methods to new domains. This progress has spurred a conspicuous optimism in computational biology. This optimism, in turn, has promoted a rapid increase in collaboration between specialists of biology with specialists of computer science. Through sheer complexity, however, many important biological problems are at present intractable, and it is not clear whether we will ever be able to solve such problems. We are in the process of learning what kind of model and what kind of analysis and synthesis techniques to use for a particular problem. Some existing formalisms have been readily used in biological problems, others have been adapted to biological needs, and still others have been especially developed for biological systems. This Research Topic has examples of cases (1) employing existing methods, (2) adapting methods to biology, and (3) developing new methods. We can also see discrete and Boolean models, and the use of both simulators and model checkers. Synthesis is exemplified by manual and by machine-learning methods. We hope that the articles collected in this Research Topic will stimulate new research.

Formal Methods in Macro-Biology

Formal Methods in Macro-Biology PDF Author: François Fages
Publisher: Springer
ISBN: 3319103989
Category : Computers
Languages : en
Pages : 204

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Book Description
This book constitutes the refereed proceedings of the First International Conference on Formal Methods in Macro-Biology, FMMB 2014, held in Nouméa, New Caledonia, in September 2014. The 7 revised full and 3 short papers presented together with 7 invited presentations were carefully reviewed and selected from 17 submissions. The scientific program consists of papers on a wide variety of topics, including ecological systems, medical applications, logical frameworks, and discrete continuous and hybrid models for the analysis of biological systems at macroscopic levels.

Computational Methods in Systems Biology

Computational Methods in Systems Biology PDF Author: Corrado Priami
Publisher: Springer Science & Business Media
ISBN: 3540461663
Category : Computers
Languages : en
Pages : 332

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Book Description
This book constitutes the refereed proceedings of the International Conference on Computational Methods in Systems Biology, CMSB 2006, held in Trento, Italy, in October 2006. The 22 fully revised papers presented together with 2 invited talks were carefully reviewed and selected from 68 submissions. The papers present a variety of techniques from computer sciences, such as language design, concurrency theory, software engineering, and formal methods.

Leveraging Applications of Formal Methods

Leveraging Applications of Formal Methods PDF Author: Tiziana Margaria-Steffen
Publisher: Springer Science & Business Media
ISBN: 3540489282
Category : Computers
Languages : en
Pages : 205

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Book Description
This book constitutes the thoroughly refereed post-proceedings of the First International Symposium on Leveraging Applications of Formal Methods, ISoLA 2004, held in Paphos, Cyprus in October/November 2004. The 12 revised full papers presented were carefully selected from more than 70 submissions. The papers discuss issues related to the adoption and use of rigorous tools and methods for the specification, analysis, verification, certification, construction, test, and maintenance of systems. In particular, by discussing common problems, requirements, algorithms, methodologies, and practices, ISoLA aims at supporting researchers in their quest to improve the utility, reliability, flexibility, and efficiency of tools for building systems, and users in their search for adequate solutions to their problems.

Formal Methods for Dynamical Systems

Formal Methods for Dynamical Systems PDF Author: Marco Bernardo
Publisher: Springer
ISBN: 3642388744
Category : Computers
Languages : en
Pages : 186

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Book Description
This book presents 5 tutorial lectures given by leading researchers at the 13th edition of the International School on Formal Methods for the Design of Computer, Communication and Software Systems, SFM 2013, held in Bertinoro, Italy, in June 2013. SFM 2013 was devoted to dynamical systems and covered several topics including chaotic dynamics; information theory; systems biology; hybrid systems; quantum computing; and automata-based models and model checking.

Computer Aided Verification

Computer Aided Verification PDF Author: Armin Biere
Publisher: Springer
ISBN: 331908867X
Category : Computers
Languages : en
Pages : 904

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Book Description
This book constitutes the proceedings of the 26th International Conference on Computer Aided Verification, CAV 2014, held as part of the Vienna Summer of Logic, VSL 2014, in Vienna, Austria, in July 2014. The 46 regular papers and 11 short papers presented in this volume were carefully reviewed and selected from a total of 175 regular and 54 short paper submissions. The contributions are organized in topical sections named: software verification; automata; model checking and testing; biology and hybrid systems; games and synthesis; concurrency; SMT and theorem proving; bounds and termination; and abstraction.

FM 2009: Formal Methods

FM 2009: Formal Methods PDF Author: Ana Cavalcanti
Publisher: Springer
ISBN: 3642050891
Category : Computers
Languages : en
Pages : 836

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Book Description
th FM 2009, the 16 International Symposium on Formal Methods, marked the 10th an- versary of the First World Congress on Formal Methods that was held in 1999 in Toulouse, France. We wished to celebrate this by advertising and organizing FM 2009 as the Second World Congress in the FM series, aiming to once again bring together the formal methods communities from all over the world. The statistics displayed in the table on the next page include the number of countries represented by the Programme Committee members, as well as of the authors of submitted and accepted papers. Novel this year was a special track on tools and industrial applications. Subm- sions of papers on these topics were especially encouraged, but not given any special treatment. (It was just as hard to get a special track paper accepted as any other paper.) What we did promote, however, was a discussion of how originality, contri- tion, and soundness should be judged for these papers. The following questions were used by our Programme Committee.

Formal Methods: Foundations and Applications

Formal Methods: Foundations and Applications PDF Author: Christiano Braga
Publisher: Springer
ISBN: 3319150758
Category : Computers
Languages : en
Pages : 189

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Book Description
This book constitutes the thoroughly refereed post-conference proceedings of the 17th Brazilian Symposium on Formal Methods, SBMF 2014, held in Maceió, Brazil, in September/October 2014. The 9 revised full papers presented together with 2 invited talks were carefully reviewed and selected from 34 submissions. SBMF is an event devoted to the dissemination of the development and use of formal methods for the construction of high quality computational systems, aiming to promote opportunities for researchers with interests in formal methods to discuss the recent advances in this area.

Bio-Inspired Computational Intelligence and Applications

Bio-Inspired Computational Intelligence and Applications PDF Author: Dr. Kang Li
Publisher: Springer Science & Business Media
ISBN: 3540747680
Category : Computers
Languages : en
Pages : 823

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Book Description
This book is part of a two-volume work that constitutes the refereed proceedings of the International Conference on Life System Modeling and Simulation, LSMS 2007, held in Shanghai, China, September 2007. Coverage includes advanced neural network theory, advanced evolutionary computing theory, ant colonies and particle swarm optimization, intelligent modeling, monitoring, and control of complex nonlinear systems, as well as biomedical signal processing, imaging and visualization.

Formal Modeling: Actors; Open Systems, Biological Systems

Formal Modeling: Actors; Open Systems, Biological Systems PDF Author: Gul Agha
Publisher: Springer Science & Business Media
ISBN: 3642249329
Category : Computers
Languages : en
Pages : 465

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Book Description
This Festschrift volume, published in honor of Carolyn Talcott on the occasion of her 70th birthday, contains a collection of papers presented at a symposium held in Menlo Park, California, USA, in November 2011. Carolyn Talcott is a leading researcher and mentor of international renown among computer scientists. She has made key contributions to a number of areas of computer science including: semantics and verification of progamming languages; foundations of actor-based systems; middleware, meta-architectures, and systems; Maude and rewriting logic; and computational biology. The 21 papers presented are organized in topical sections named: Essays on Carolyn Talcott; actors and programming languages; cyberphysical systems; middleware and meta-architectures; formal methods and reasoning tools; and computational biology.