Computational Methods for Segmentation of Multi-modal Multi-dimensional Cardiac Images

Computational Methods for Segmentation of Multi-modal Multi-dimensional Cardiac Images PDF Author: Shusil Dangi
Publisher:
ISBN:
Category : Heart
Languages : en
Pages : 192

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Book Description
"Segmentation of the heart structures helps compute the cardiac contractile function quantified via the systolic and diastolic volumes, ejection fraction, and myocardial mass, representing a reliable diagnostic value. Similarly, quantification of the myocardial mechanics throughout the cardiac cycle, analysis of the activation patterns in the heart via electrocardiography (ECG) signals, serve as good cardiac diagnosis indicators. Furthermore, high quality anatomical models of the heart can be used in planning and guidance of minimally invasive interventions under the assistance of image guidance. The most crucial step for the above mentioned applications is to segment the ventricles and myocardium from the acquired cardiac image data. Although the manual delineation of the heart structures is deemed as the gold-standard approach, it requires significant time and effort, and is highly susceptible to inter- and intra-observer variability. These limitations suggest a need for fast, robust, and accurate semi- or fully-automatic segmentation algorithms. However, the complex motion and anatomy of the heart, indistinct borders due to blood flow, the presence of trabeculations, intensity inhomogeneity, and various other imaging artifacts, makes the segmentation task challenging. In this work, we present and evaluate segmentation algorithms for multi-modal, multi-dimensional cardiac image datasets. Firstly, we segment the left ventricle (LV) blood-pool from a tri-plane 2D+time trans-esophageal (TEE) ultrasound acquisition using local phase based filtering and graph-cut technique, propagate the segmentation throughout the cardiac cycle using non-rigid registration-based motion extraction, and reconstruct the 3D LV geometry. Secondly, we segment the LV blood-pool and myocardium from an open-source 4D cardiac cine Magnetic Resonance Imaging (MRI) dataset by incorporating average atlas based shape constraint into the graph-cut framework and iterative segmentation refinement. The developed fast and robust framework is further extended to perform right ventricle (RV) blood-pool segmentation from a different open-source 4D cardiac cine MRI dataset. Next, we employ convolutional neural network based multi-task learning framework to segment the myocardium and regress its area, simultaneously, and show that segmentation based computation of the myocardial area is significantly better than that regressed directly from the network, while also being more interpretable. Finally, we impose a weak shape constraint via multi-task learning framework in a fully convolutional network and show improved segmentation performance for LV, RV and myocardium across healthy and pathological cases, as well as, in the challenging apical and basal slices in two open-source 4D cardiac cine MRI datasets. We demonstrate the accuracy and robustness of the proposed segmentation methods by comparing the obtained results against the provided gold-standard manual segmentations, as well as with other competing segmentation methods."--Abstract.

Computational Methods for Segmentation of Multi-modal Multi-dimensional Cardiac Images

Computational Methods for Segmentation of Multi-modal Multi-dimensional Cardiac Images PDF Author: Shusil Dangi
Publisher:
ISBN:
Category : Heart
Languages : en
Pages : 192

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Book Description
"Segmentation of the heart structures helps compute the cardiac contractile function quantified via the systolic and diastolic volumes, ejection fraction, and myocardial mass, representing a reliable diagnostic value. Similarly, quantification of the myocardial mechanics throughout the cardiac cycle, analysis of the activation patterns in the heart via electrocardiography (ECG) signals, serve as good cardiac diagnosis indicators. Furthermore, high quality anatomical models of the heart can be used in planning and guidance of minimally invasive interventions under the assistance of image guidance. The most crucial step for the above mentioned applications is to segment the ventricles and myocardium from the acquired cardiac image data. Although the manual delineation of the heart structures is deemed as the gold-standard approach, it requires significant time and effort, and is highly susceptible to inter- and intra-observer variability. These limitations suggest a need for fast, robust, and accurate semi- or fully-automatic segmentation algorithms. However, the complex motion and anatomy of the heart, indistinct borders due to blood flow, the presence of trabeculations, intensity inhomogeneity, and various other imaging artifacts, makes the segmentation task challenging. In this work, we present and evaluate segmentation algorithms for multi-modal, multi-dimensional cardiac image datasets. Firstly, we segment the left ventricle (LV) blood-pool from a tri-plane 2D+time trans-esophageal (TEE) ultrasound acquisition using local phase based filtering and graph-cut technique, propagate the segmentation throughout the cardiac cycle using non-rigid registration-based motion extraction, and reconstruct the 3D LV geometry. Secondly, we segment the LV blood-pool and myocardium from an open-source 4D cardiac cine Magnetic Resonance Imaging (MRI) dataset by incorporating average atlas based shape constraint into the graph-cut framework and iterative segmentation refinement. The developed fast and robust framework is further extended to perform right ventricle (RV) blood-pool segmentation from a different open-source 4D cardiac cine MRI dataset. Next, we employ convolutional neural network based multi-task learning framework to segment the myocardium and regress its area, simultaneously, and show that segmentation based computation of the myocardial area is significantly better than that regressed directly from the network, while also being more interpretable. Finally, we impose a weak shape constraint via multi-task learning framework in a fully convolutional network and show improved segmentation performance for LV, RV and myocardium across healthy and pathological cases, as well as, in the challenging apical and basal slices in two open-source 4D cardiac cine MRI datasets. We demonstrate the accuracy and robustness of the proposed segmentation methods by comparing the obtained results against the provided gold-standard manual segmentations, as well as with other competing segmentation methods."--Abstract.

Multi-modality Cardiac Imaging

Multi-modality Cardiac Imaging PDF Author: Patrick Clarysse
Publisher: John Wiley & Sons
ISBN: 1848212356
Category : Technology & Engineering
Languages : en
Pages : 370

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Book Description
The imaging of moving organs such as the heart, in particular, is a real challenge because of its movement. This book presents current and emerging methods developed for the acquisition of images of moving organs in the five main medical imaging modalities: conventional X-rays, computed tomography (CT), magnetic resonance imaging (MRI), nuclear imaging and ultrasound. The availability of dynamic image sequences allows for the qualitative and quantitative assessment of an organ’s dynamics, which is often linked to pathologies.

Multi Modality State-of-the-Art Medical Image Segmentation and Registration Methodologies

Multi Modality State-of-the-Art Medical Image Segmentation and Registration Methodologies PDF Author: Ayman S. El-Baz
Publisher: Springer Science & Business Media
ISBN: 1441982043
Category : Medical
Languages : en
Pages : 369

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Book Description
With the advances in image guided surgery for cancer treatment, the role of image segmentation and registration has become very critical. The central engine of any image guided surgery product is its ability to quantify the organ or segment the organ whether it is a magnetic resonance imaging (MRI) and computed tomography (CT), X-ray, PET, SPECT, Ultrasound, and Molecular imaging modality. Sophisticated segmentation algorithms can help the physicians delineate better the anatomical structures present in the input images, enhance the accuracy of medical diagnosis and facilitate the best treatment planning system designs. The focus of this book in towards the state of the art techniques in the area of image segmentation and registration.

Statistical Atlases and Computational Models of the Heart. Multi-Disease, Multi-View, and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge

Statistical Atlases and Computational Models of the Heart. Multi-Disease, Multi-View, and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge PDF Author: Esther Puyol Antón
Publisher: Springer Nature
ISBN: 3030937224
Category : Computers
Languages : en
Pages : 397

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Book Description
This book constitutes the proceedings of the 12th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2021, as well as the M&Ms-2 Challenge: Multi-Disease, Multi-View and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge. The 25 regular workshop papers included in this volume were carefully reviewed and selected after being revised. They deal with cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, artificial intelligence, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods. In addition, 15 papers from the M&MS-2 challenge are included in this volume. The Multi-Disease, Multi-View & Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge (M&Ms-2) is focusing on the development of generalizable deep learning models for the Right Ventricle that can maintain good segmentation accuracy on different centers, pathologies and cardiac MRI views. There was a total of 48 submissions to the workshop.

Two and Three Dimensional Segmentation of Multimodal Imagery

Two and Three Dimensional Segmentation of Multimodal Imagery PDF Author: Sreenath Rao Vantaram
Publisher:
ISBN:
Category : Image processing
Languages : en
Pages : 382

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Book Description
"The role of segmentation in the realms of image understanding/analysis, computer vision, pattern recognition, remote sensing and medical imaging in recent years has been significantly augmented due to accelerated scientific advances made in the acquisition of image data. This low-level analysis protocol is critical to numerous applications, with the primary goal of expediting and improving the effectiveness of subsequent high-level operations by providing a condensed and pertinent representation of image information. In this research, we propose a novel unsupervised segmentation framework for facilitating meaningful segregation of 2-D/3-D image data across multiple modalities (color, remote-sensing and biomedical imaging) into non-overlapping partitions using several spatial-spectral attributes. initially, our framework exploits the information obtained from detecting edges inherent in the data. To this effect, by using a vector gradient detection technique, pixels without edges are grouped and individually labeled to partition some initial portion of the input image content. Pixels that contain higher gradient densities are included by the dynamic generation of segments as the algorithm progresses to generate an initial region map. Subsequently, texture modeling is performed and the obtained gradient, texture and intensity information along with the aforementioned initial partition map are used to perform a multivariate refinement procedure, to fuse groups with similar characteristics yielding the final output segmentation. Experimental results obtained in comparison to published/state-of-the-art segmentation techniques for color as well as multi/hyperspectral imagery, demonstrate the advantages of the proposed method. Furthermore, for the purpose of achieving improved computational efficiency we propose an extension of the aforestated methodology in a multi-resolution framework, demonstrated on color images. Finally, this research also encompasses a 3-D extension of the aforementioned algorithm demonstrated on medical (Magnetic Resonance Imaging / Computed Tomography) volumes."--Abstract.

Statistical Atlases and Computational Models of the Heart. Multi-Sequence CMR Segmentation, CRT-EPiggy and LV Full Quantification Challenges

Statistical Atlases and Computational Models of the Heart. Multi-Sequence CMR Segmentation, CRT-EPiggy and LV Full Quantification Challenges PDF Author: Mihaela Pop
Publisher: Springer Nature
ISBN: 3030390748
Category : Computers
Languages : en
Pages : 426

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Book Description
This book constitutes the thoroughly refereed post-workshop proceedings of the 10th International Workshop on Statistical Atlases and Computational Models of the Heart: Atrial Segmentation and LV Quantification Challenges, STACOM 2019, held in conjunction with MICCAI 2019, in Shenzhen, China, in October 2019. The 42 revised full workshop papers were carefully reviewed and selected from 76 submissions. The topics of the workshop included: cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods.

Myocardial Pathology Segmentation Combining Multi-Sequence Cardiac Magnetic Resonance Images

Myocardial Pathology Segmentation Combining Multi-Sequence Cardiac Magnetic Resonance Images PDF Author: Xiahai Zhuang
Publisher: Springer Nature
ISBN: 3030656519
Category : Computers
Languages : en
Pages : 187

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Book Description
This book constitutes the First Myocardial Pathology Segmentation Combining Multi-Sequence CMR Challenge, MyoPS 2020, which was held in conjunction with the 23rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2020, in Lima, Peru, in October 2020. The challenge took place virtually due to the COVID-19 crisis. The 12 full and 4 short papers presented in this volume were carefully reviewed and selected form numerous submissions. This challenge aims not only to benchmark various myocardial pathology segmentation algorithms, but also to cover the topic of general cardiac image segmentation, registration and modeling, and raise discussions for further technical development and clinical deployment.

Deep Learning Approaches to Multi-Modal Biomedical Image Segmentation

Deep Learning Approaches to Multi-Modal Biomedical Image Segmentation PDF Author: Nelson Frank
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
Deep learning techniques have been shown to produce state-of-the-art performance in segmenting biomedical images. These techniques, however, are highly dependent on the quantity and quality of available training data, as well as their capacity to represent complex relationships, which is dependent on the size of the network and limited by the computational resources of the machine(s) on which they are trained. In this work, we performed two experiments. First, we explored multi-stream model configurations that can leverage available data from multiple unpaired biomedical imaging modalities to learn a shared representation. Specifically, segmentation of cardiac CT and MRI was done to see if this learns the shared anatomical features and thus performs better than individual models trained on each modality. Second, we compared our full deep learning segmentation pipeline as applied to paired multi-modal brain images against other existing publicly available pipelines. From these experiments, we found that (1) multi-stream architectures can achieve better results in unpaired multi-modal segmentation compared to single-stream models, however, the specific configuration with the best performance is in disagreement with previously published results; and (2) careful adjustment of deep learning pipeline configurations to our specific data set and hardware constraints yields improved segmentation accuracy over publicly available state-of-the-art solutions in paired multi-modal image segmentation.

Statistical Atlases and Computational Models of the Heart. M&Ms and EMIDEC Challenges

Statistical Atlases and Computational Models of the Heart. M&Ms and EMIDEC Challenges PDF Author: Esther Puyol Anton
Publisher: Springer Nature
ISBN: 3030681076
Category : Computers
Languages : en
Pages : 427

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Book Description
This book constitutes the proceedings of the 11th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2020, as well as two challenges: M&Ms - The Multi-Centre, Multi-Vendor, Multi-Disease Segmentation Challenge, and EMIDEC - Automatic Evaluation of Myocardial Infarction from Delayed-Enhancement Cardiac MRI Challenge. The 43 full papers included in this volume were carefully reviewed and selected from 70 submissions. They deal with cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, artificial intelligence, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods.

Multi-Modality Imaging

Multi-Modality Imaging PDF Author: Mauren Abreu de Souza
Publisher: Springer
ISBN: 331998974X
Category : Medical
Languages : en
Pages : 265

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Book Description
This book presents different approaches on multi-modality imaging with a focus on biomedical applications. Medical imaging can be divided into two categories: functional (related to physiological body measurements) and anatomical (structural) imaging modalities. In particular, this book covers imaging combinations coming from the usual popular modalities (such as the anatomical modalities, e.g. X-ray, CT and MRI), and it also includes some promising and new imaging modalities that are still being developed and improved (such as infrared thermography (IRT) and photoplethysmography imaging (PPGI)), implying potential approaches for innovative biomedical applications. Moreover, this book includes a variety of tools on computer vision, imaging processing, and computer graphics, which led to the generation and visualization of 3D models, making the most recent advances in this area possible. This is an ideal book for students and biomedical engineering researchers covering the biomedical imaging field.