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Author: Johannes F. Knabe
Publisher: Springer
ISBN: 3642302963
Category : Technology & Engineering
Languages : en
Pages : 125
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Book Description
Genetic Regulatory Networks (GRNs) in biological organisms are primary engines for cells to enact their engagements with environments, via incessant, continually active coupling. In differentiated multicellular organisms, tremendous complexity has arisen in the course of evolution of life on earth. Engineering and science have so far achieved no working system that can compare with this complexity, depth and scope of organization. Abstracting the dynamics of genetic regulatory control to a computational framework in which artificial GRNs in artificial simulated cells differentiate while connected in a changing topology, it is possible to apply Darwinian evolution in silico to study the capacity of such developmental/differentiated GRNs to evolve. In this volume an evolutionary GRN paradigm is investigated for its evolvability and robustness in models of biological clocks, in simple differentiated multicellularity, and in evolving artificial developing 'organisms' which grow and express an ontogeny starting from a single cell interacting with its environment, eventually including a changing local neighbourhood of other cells. These methods may help us understand the genesis, organization, adaptive plasticity, and evolvability of differentiated biological systems, and may also provide a paradigm for transferring these principles of biology's success to computational and engineering challenges at a scale not previously conceivable.
Author: Johannes F. Knabe
Publisher: Springer
ISBN: 3642302963
Category : Technology & Engineering
Languages : en
Pages : 125
Get Book Here
Book Description
Genetic Regulatory Networks (GRNs) in biological organisms are primary engines for cells to enact their engagements with environments, via incessant, continually active coupling. In differentiated multicellular organisms, tremendous complexity has arisen in the course of evolution of life on earth. Engineering and science have so far achieved no working system that can compare with this complexity, depth and scope of organization. Abstracting the dynamics of genetic regulatory control to a computational framework in which artificial GRNs in artificial simulated cells differentiate while connected in a changing topology, it is possible to apply Darwinian evolution in silico to study the capacity of such developmental/differentiated GRNs to evolve. In this volume an evolutionary GRN paradigm is investigated for its evolvability and robustness in models of biological clocks, in simple differentiated multicellularity, and in evolving artificial developing 'organisms' which grow and express an ontogeny starting from a single cell interacting with its environment, eventually including a changing local neighbourhood of other cells. These methods may help us understand the genesis, organization, adaptive plasticity, and evolvability of differentiated biological systems, and may also provide a paradigm for transferring these principles of biology's success to computational and engineering challenges at a scale not previously conceivable.
Author: Johannes F. Knabe
Publisher: Springer
ISBN: 9783642302978
Category : Computers
Languages : en
Pages : 122
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Book Description
Genetic Regulatory Networks (GRNs) in biological organisms are primary engines for cells to enact their engagements with environments, via incessant, continually active coupling. In differentiated multicellular organisms, tremendous complexity has arisen in the course of evolution of life on earth. Engineering and science have so far achieved no working system that can compare with this complexity, depth and scope of organization. Abstracting the dynamics of genetic regulatory control to a computational framework in which artificial GRNs in artificial simulated cells differentiate while connected in a changing topology, it is possible to apply Darwinian evolution in silico to study the capacity of such developmental/differentiated GRNs to evolve. In this volume an evolutionary GRN paradigm is investigated for its evolvability and robustness in models of biological clocks, in simple differentiated multicellularity, and in evolving artificial developing 'organisms' which grow and express an ontogeny starting from a single cell interacting with its environment, eventually including a changing local neighbourhood of other cells. These methods may help us understand the genesis, organization, adaptive plasticity, and evolvability of differentiated biological systems, and may also provide a paradigm for transferring these principles of biology's success to computational and engineering challenges at a scale not previously conceivable.
Author: Hitoshi Iba
Publisher: John Wiley & Sons
ISBN: 1119079780
Category : Computers
Languages : en
Pages : 464
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Book Description
Introducing a handbook for gene regulatory network research using evolutionary computation, with applications for computer scientists, computational and system biologists This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics. • Provides a reference for current and future research in gene regulatory networks (GRN) using evolutionary computation (EC) • Covers sub-domains of GRN research using EC, such as expression profile analysis, reverse engineering, GRN evolution, applications • Contains useful contents for courses in gene regulatory networks, systems biology, computational biology, and synthetic biology • Delivers state-of-the-art research in genetic algorithms, genetic programming, and swarm intelligence Evolutionary Computation in Gene Regulatory Network Research is a reference for researchers and professionals in computer science, systems biology, and bioinformatics, as well as upper undergraduate, graduate, and postgraduate students. Hitoshi Iba is a Professor in the Department of Information and Communication Engineering, Graduate School of Information Science and Technology, at the University of Tokyo, Toyko, Japan. He is an Associate Editor of the IEEE Transactions on Evolutionary Computation and the journal of Genetic Programming and Evolvable Machines. Nasimul Noman is a lecturer in the School of Electrical Engineering and Computer Science at the University of Newcastle, NSW, Australia. From 2002 to 2012 he was a faculty member at the University of Dhaka, Bangladesh. Noman is an Editor of the BioMed Research International journal. His research interests include computational biology, synthetic biology, and bioinformatics.
Author: Yaochu Jin
Publisher: Springer Science & Business Media
ISBN: 3540899677
Category : Computers
Languages : en
Pages : 336
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Book Description
Biological systems are inherently stochastic and uncertain. Thus, research in bioinformatics, biomedical engineering and computational biology has to deal with a large amount of uncertainties. Fuzzy logic has shown to be a powerful tool in capturing different uncertainties in engineering systems. In recent years, fuzzy logic based modeling and analysis approaches are also becoming popular in analyzing biological data and modeling biological systems. Numerous research and application results have been reported that demonstrated the effectiveness of fuzzy logic in solving a wide range of biological problems found in bioinformatics, biomedical engineering, and computational biology. Contributed by leading experts world-wide, this edited book contains 16 chapters presenting representative research results on the application of fuzzy systems to genome sequence assembly, gene expression analysis, promoter analysis, cis-regulation logic analysis and synthesis, reconstruction of genetic and cellular networks, as well as biomedical problems, such as medical image processing, electrocardiogram data classification and anesthesia monitoring and control. This volume is a valuable reference for researchers, practitioners, as well as graduate students working in the field of bioinformatics, biomedical engineering and computational biology.
Author: Karin Anna Hummel
Publisher: Springer Science & Business Media
ISBN: 3540921567
Category : Computers
Languages : en
Pages : 354
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Book Description
This book constitutes the refereed proceedings of the Third International Workshop on Self-Organizing Systems, IWSOS 2008, held in Vienna, Austria, December 10-12, 2008. The 20 revised full papers and 13 revised short papers presented were carefully selected from the 70 full and 24 short paper submissions from authors from 33 different countries. The papers are organized in topical sections on peer-to-peer systems, overlay networks as well as resource and service management.
Author: Wen Yu
Publisher: Springer Science & Business Media
ISBN: 3642031560
Category : Computers
Languages : en
Pages : 524
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Book Description
This book constitutes the proceedings of the second International Workshop on Advanced Computational Intelligence (IWACI 2009), with a sequel of IWACI 2008 successfully held in Macao, China. IWACI 2009 provided a high-level international forum for scientists, engineers, and educators to present state-of-the-art research in computational intelligence and related fields. Over the past decades, computational intelligence community has witnessed t- mendous efforts and developments in all aspects of theoretical foundations, archit- tures and network organizations, modelling and simulation, empirical study, as well as a wide range of applications across different domains. IWACI 2009 provided a great platform for the community to share their latest research results, discuss critical future research directions, stimulate innovative research ideas, as well as facilitate inter- tional multidisciplinary collaborations. IWACI 2009 received 146 submissions from about 373 authors in 26 countries and regions (Australia, Brazil, Canada, China, Chile, Hong Kong, India, Islamic Republic of Iran, Japan, Jordan, Macao, Malaysia, Mexico, Pakistan, Philippines, Qatar, Republic of Korea, Singapore, South Africa, Sri Lanka, Spain, Taiwan, Thailand, UK, USA, Ve- zuela, Vietnam, and Yemen) across six continents (Asia, Europe, North America, South America, Africa, and Oceania). Based on the rigorous peer reviews by the Program Committee members, 52 high-quality papers were selected for publication in this book, with an acceptance rate of 36.3%. These papers cover major topics of the theoretical research, empirical study, and applications of computational intelligence.
Author: René Doursat
Publisher: Springer
ISBN: 3642339026
Category : Technology & Engineering
Languages : en
Pages : 512
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Book Description
Generally, spontaneous pattern formation phenomena are random and repetitive, whereas elaborate devices are the deterministic product of human design. Yet, biological organisms and collective insect constructions are exceptional examples of complex systems that are both self-organized and architectural. This book is the first initiative of its kind toward establishing a new field of research, Morphogenetic Engineering, to explore the modeling and implementation of “self-architecturing” systems. Particular emphasis is placed on the programmability and computational abilities of self-organization, properties that are often underappreciated in complex systems science—while, conversely, the benefits of self-organization are often underappreciated in engineering methodologies. Altogether, the aim of this work is to provide a framework for and examples of a larger class of “self-architecturing” systems, while addressing fundamental questions such as br” How do biological organisms carry out morphogenetic tasks so reliably? br” Can we extrapolate their self-formation capabilities to engineered systems?br” Can physical systems be endowed with information (or informational systems be embedded in physics) so as to create autonomous morphologies and functions?br” What are the core principles and best practices for the design and engineering of such morphogenetic systems?
Author: Corrado Priami
Publisher: Springer
ISBN: 3540922733
Category : Computers
Languages : en
Pages : 204
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Book Description
Technology is taking us to a world where myriads of heavily networked devices interact with the physical world in multiple ways, and at many levels, from the globalInternetdowntomicroandnanodevices. Manyofthesedevicesarehighly mobile and autonomous and must adapt to the surrounding environment in a totally unsupervised way. A fundamental research challenge is the design of robust decentralized c- puting systemsthat arecapableofoperating in changing environmentsandwith noisy input, and yet exhibit the desired behavior and response time, under c- straints such as energy consumption, size, and processing power. These systems should be able to adapt and learn how to react to unforeseen scenarios as well as to display properties comparable to social entities. The observation of nature has brought us many great and unforeseen concepts. Biological systems are able to handle many of these challenges with an elegance and e?ciency far beyond currenthumanartifacts. Basedonthisobservation,bio-inspiredapproacheshave been proposed as a means of handling the complexity of such systems. The goal is to obtain methods to engineer technical systems, which are of a stability and e?ciency comparable to those found in biological entities. This Special Issue on Biological and Biologically-inspired Communication contains the best papers from the Second International Conference on Bio- Inspired Models of Network, Information, and Computing Systems (BIONET- ICS 2007). The BIONETICS conference aims to bring together researchers and scientistsfromseveraldisciplines incomputerscienceandengineeringwhereb- inspired methods are investigated, as well as from bioinformatics, to deepen the information exchange and collaboration among the di?erent communities.
Author: Yan Meng
Publisher: Springer Science & Business Media
ISBN: 3642207596
Category : Computers
Languages : en
Pages : 273
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Book Description
Self-organizing approaches inspired from biological systems, such as social insects, genetic, molecular and cellular systems under morphogenesis, and human mental development, has enjoyed great success in advanced robotic systems that need to work in dynamic and changing environments. Compared with classical control methods for robotic systems, the major advantages of bio-inspired self-organizing robotic systems include robustness, self-repair and self-healing in the presence of system failures and/or malfunctions, high adaptability to environmental changes, and autonomous self-organization and self-reconfiguration without a centralized control. “Bio-inspired Self-organizing Robotic Systems” provides a valuable reference for scientists, practitioners and research students working on developing control algorithms for self-organizing engineered collective systems, such as swarm robotic systems, self-reconfigurable modular robots, smart material based robotic devices, unmanned aerial vehicles, and satellite constellations.
Author: Tan, Ying
Publisher: IGI Global
ISBN: 1466695730
Category : Technology & Engineering
Languages : en
Pages : 889
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Book Description
Studies on robotics applications have grown substantially in recent years, with swarm robotics being a relatively new area of research. Inspired by studies in swarm intelligence and robotics, swarm robotics facilitates interactions between robots as well as their interactions with the environment. The Handbook of Research on Design, Control, and Modeling of Swarm Robotics is a collection of the most important research achievements in swarm robotics thus far, covering the growing areas of design, control, and modeling of swarm robotics. This handbook serves as an essential resource for researchers, engineers, graduates, and senior undergraduates with interests in swarm robotics and its applications.
