Neural Stem Cell Assays

Neural Stem Cell Assays PDF Author: Navjot Kaur
Publisher: John Wiley & Sons
ISBN: 1118308255
Category : Science
Languages : en
Pages : 311

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Book Description
Neural stem cells offer a valuable model system for delineating the cellular and developmental processes in normal and diseased states of the central nervous system. In particular, neural stem cells have huge potential in regenerative medicine, owing to their expansion capability in culture and the ability to differentiate into multiple sub-neural lineages. Neural Stem Cell Assays provides a detailed and comprehensive review of the basic methods for neural stem cell cultures. Including an overview of progress in the field over the past decade, Neural Stem Cell Assays is a one-stop reference for consistent methods and reliable tools that span the entire assay work flow, from isolation or generation of neural stem cells to characterization, manipulation and final application of neural stem cells in disease paradigms such as Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis. An excellent source of information for academic, pharmaceutical and biotechnology researchers who are new to the neural stem cell field, Neural Stem Cell Assays is an invaluable to experienced users who wish to integrate newly developed tools and technologies into their workflow. The book also covers important course material for students at the undergraduate and graduate level who are learning the basics of neural stem cell cultures, and differentiation to sub-neural lineages.

Neural Stem Cell Assays

Neural Stem Cell Assays PDF Author: Navjot Kaur
Publisher: John Wiley & Sons
ISBN: 1118308255
Category : Science
Languages : en
Pages : 311

Get Book Here

Book Description
Neural stem cells offer a valuable model system for delineating the cellular and developmental processes in normal and diseased states of the central nervous system. In particular, neural stem cells have huge potential in regenerative medicine, owing to their expansion capability in culture and the ability to differentiate into multiple sub-neural lineages. Neural Stem Cell Assays provides a detailed and comprehensive review of the basic methods for neural stem cell cultures. Including an overview of progress in the field over the past decade, Neural Stem Cell Assays is a one-stop reference for consistent methods and reliable tools that span the entire assay work flow, from isolation or generation of neural stem cells to characterization, manipulation and final application of neural stem cells in disease paradigms such as Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis. An excellent source of information for academic, pharmaceutical and biotechnology researchers who are new to the neural stem cell field, Neural Stem Cell Assays is an invaluable to experienced users who wish to integrate newly developed tools and technologies into their workflow. The book also covers important course material for students at the undergraduate and graduate level who are learning the basics of neural stem cell cultures, and differentiation to sub-neural lineages.

The Cognitive Thalamus

The Cognitive Thalamus PDF Author: Yuri B. Saalmann
Publisher: Frontiers Media SA
ISBN: 2889195414
Category : Neurosciences. Biological psychiatry. Neuropsychiatry
Languages : en
Pages : 127

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Book Description
Cognitive processing is commonly conceptualized as being restricted to the cerebral cortex. Accordingly, electrophysiology, neuroimaging and lesion studies involving human and animal subjects have almost exclusively focused on defining roles for cerebral cortical areas in cognition. Roles for the thalamus in cognition have been largely ignored despite the fact that the extensive connectivity between the thalamus and cerebral cortex gives rise to a closely coupled thalamo-cortical system. However, in recent years, growing interest in the thalamus as much more than a passive sensory structure, as well as methodological advances such as high-resolution functional magnetic resonance imaging of the thalamus and improved electrode targeting to subregions of thalamic nuclei using electrical stimulation and diffusion tensor imaging, have fostered research into thalamic contributions to cognition. Evidence suggests that behavioral context modulates processing in primary sensory, or first-order, thalamic nuclei (for example, the lateral geniculate and ventral posterior nuclei), allowing attentional filtering of incoming sensory information at an early stage of brain processing. Behavioral context appears to more strongly influence higher-order thalamic nuclei (for example, the pulvinar and mediodorsal nucleus), which receive major input from the cortex rather than the sensory periphery. Such higher-order thalamic nuclei have been shown to regulate information transmission in frontal and higher-order sensory cortex according to cognitive demands. This Research Topic aims to bring together neuroscientists who study different parts of the thalamus, particularly thalamic nuclei other than the primary sensory relays, and highlight the thalamic contributions to attention, memory, reward processing, decision-making, and language. By doing so, an emphasis is also placed on neural mechanisms common to many, if not all, of these cognitive operations, such as thalamo-cortical interactions and modulatory influences from sources in the brainstem and basal ganglia. The overall view that emerges is that the thalamus is a vital node in brain networks supporting cognition.

Cancer-Associated Thrombosis

Cancer-Associated Thrombosis PDF Author: Alok A. Khorana
Publisher: CRC Press
ISBN: 1420048007
Category : Medical
Languages : en
Pages : 290

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Book Description
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides

Culture Centers in Higher Education

Culture Centers in Higher Education PDF Author: Lori D. Patton
Publisher: Taylor & Francis
ISBN: 1000977218
Category : Education
Languages : en
Pages : 148

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Book Description
Are cultural centers ethnic enclaves of segregation, or safe havens that provide minority students with social support that promotes persistence and retention?Though Black cultural centers boast a 40-year history, there is much misinformation about them and the ethnic counterparts to which they gave rise. Moreover, little is known about their historical roots, current status, and future prospects. The literature has largely ignored the various culture center models, and the role that such centers play in the experiences of college students. This book fills a significant void in the research on ethnic minority cultural centers, offers the historic background to their establishment and development, considers the circumstances that led to their creation, examines the roles they play on campus, explores their impact on retention and campus climate, and provides guidelines for their management in the light of current issues and future directions.In the first part of this volume, the contributors provide perspectives on culture centers from the point of view of various racial/ethnic identity groups, Latina/o, Asian, American Indian, and African American. Part II offers theoretical perspectives that frame the role of culture centers from the point of view of critical race theory, student development theory, and a social justice framework. Part III focuses specifically on administrative and practice-oriented themes, addressing such issues as the relative merits of full- and part-time staff, of race/ethnic specific as opposed to multicultural centers, relations with the outside community, and integration with academic and student affairs to support the mission of the institution. For administrators and student affairs educators who are unfamiliar with these facilities, and want to support an increasingly diverse student body, this book situates such centers within the overall strategy of improving campus climate, and makes the case for sustaining them. Where none as yet exist, this book offers a rationale and blueprint for creating such centers. For leaders of culture centers this book constitutes a valuable tool for assessing their viability, improving their performance, and ensuring their future relevance – all considerations of increased importance when budgets and resources are strained. This book also provides a foundation for researchers interested in further investigating the role of these centers in higher education.

Microbial Evolution and Co-Adaptation

Microbial Evolution and Co-Adaptation PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309131219
Category : Science
Languages : en
Pages : 330

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Book Description
Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

Radiation Hydrodynamics

Radiation Hydrodynamics PDF Author: John I. Castor
Publisher: Cambridge University Press
ISBN: 0521833094
Category : Science
Languages : en
Pages : 369

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Book Description
Publisher Description

Expanding Underrepresented Minority Participation

Expanding Underrepresented Minority Participation PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309159687
Category : Education
Languages : en
Pages : 229

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Book Description
In order for the United States to maintain the global leadership and competitiveness in science and technology that are critical to achieving national goals, we must invest in research, encourage innovation, and grow a strong and talented science and technology workforce. Expanding Underrepresented Minority Participation explores the role of diversity in the science, technology, engineering and mathematics (STEM) workforce and its value in keeping America innovative and competitive. According to the book, the U.S. labor market is projected to grow faster in science and engineering than in any other sector in the coming years, making minority participation in STEM education at all levels a national priority. Expanding Underrepresented Minority Participation analyzes the rate of change and the challenges the nation currently faces in developing a strong and diverse workforce. Although minorities are the fastest growing segment of the population, they are underrepresented in the fields of science and engineering. Historically, there has been a strong connection between increasing educational attainment in the United States and the growth in and global leadership of the economy. Expanding Underrepresented Minority Participation suggests that the federal government, industry, and post-secondary institutions work collaboratively with K-12 schools and school systems to increase minority access to and demand for post-secondary STEM education and technical training. The book also identifies best practices and offers a comprehensive road map for increasing involvement of underrepresented minorities and improving the quality of their education. It offers recommendations that focus on academic and social support, institutional roles, teacher preparation, affordability and program development.

Nucleic Acid Biosensors for Environmental Pollution Monitoring

Nucleic Acid Biosensors for Environmental Pollution Monitoring PDF Author: Marco Mascini
Publisher: Royal Society of Chemistry
ISBN: 1849731314
Category : Science
Languages : en
Pages : 187

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Book Description
This book discusses recent advances in the use of nucleic acid based biosensors and related bioanalytical assays for environmental monitoring.

Handbook of Drug Interactions

Handbook of Drug Interactions PDF Author: Ashraf Mozayani
Publisher: Springer Science & Business Media
ISBN: 1592596541
Category : Medical
Languages : en
Pages : 662

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Book Description
A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.

Newton's Football

Newton's Football PDF Author: Allen St. John
Publisher: Ballantine Books
ISBN: 034554515X
Category : Sports & Recreation
Languages : en
Pages : 273

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Book Description
In the bestselling tradition of Freakonomics and Scorecasting comes a clever and accessible look at the big ideas underlying the science of football. Did you hear the one about the MacArthur genius physicist and the NFL coach? It’s not a joke. It’s actually an innovative way to understand chaos theory, and the remarkable complexity of modern professional football. In Newton’s Football, journalist and New York Times bestselling author Allen St. John and TED Speaker and former Yale professor Ainissa Ramirez explore the unexpected science behind America’s Game. Whether it’s Jerry Rice finding the common ground between quantum physics and the West Coast offense or an Ivy League biologist explaining—at a granular level—exactly how a Big Mac morphs into an outside linebacker, Newton’s Football illuminates football—and science—through funny, insightful stories told by some of the world’s sharpest minds. With a clear-eyed empirical approach—and an exuberant affection for the game—St. John and Ramirez address topics that have long beguiled scientists and football fans alike, including: • the unlikely evolution of the football (or, as they put it, “The Divinely Random Bounce of the Prolate Spheroid”) • what Vince Lombardi has in common with Isaac Newton • how the hardwired behavior of monkeys can explain a head coach’s reluctance to go for it on fourth-down • why a gruesome elevator accident jump-started the evolution of placekicking • how Teddy Roosevelt saved football using the same behavioral science concept that Dreamworks would use to save Shrek • why woodpeckers don’t get concussions • how better helmets actually made the game more dangerous Every Sunday the NFL shares a secret with only its savviest fans: The game isn’t just a clash of bodies, it’s a clash of ideas. The greatest minds in football have always possessed an instinctual grasp of science, understanding the big ideas and gritty realities that inform the game’s rich past, as well as its increasingly uncertain future. Blending smart reporting, counterintuitive creativity, and compelling narrative, Newton’s Football takes gridiron analysis to the next level, giving fans a book that entertains, enlightens, and explains the game anew. Praise for Newton’s Football “It was with great interest that I read Newton’s Football. I’m a fan of applying of science to sport and Newton’s Football truly delivers. The stories are as engaging as they are informative. This is a great read for all football fans.”—Mark Cuban “A delightfully improbable book putting science nerds and sports fans on the same page.”—Booklist “This breezily-written but informative book should pique the interest of any serious football fan in the twenty-first century.”—The American Spectator “The authors have done a worthy job of combining popular science and sports into a work that features enough expertise on each topic to satisfy nerds and jocks alike. . . . The writers succeed in their task thanks to in-depth scientific knowledge, a wonderful grasp of football’s past and present, interviews with a wide array of experts, and witty prose. . . . [Newton’s Football is] fun and thought-provoking, proving that football is a mind game as much as it is a ball game.”—Publishers Weekly