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Author: MAX EDITORIAL
Publisher: Max Editorial
ISBN: 1779716842
Category : Business & Economics
Languages : en
Pages : 69
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Book Description
O que é Blockchain? Blockchain é uma tecnologia de registro distribuído que permite a manutenção de uma base de dados segura e confiável. Ela é baseada em um sistema de blocos encadeados, cada um contendo um conjunto de informações. Esses blocos são protegidos por criptografia e distribuídos por uma rede de computadores. As principais características do Blockchain são: Descentralização: a rede Blockchain não é controlada por um único órgão ou entidade, mas por uma rede de computadores. Isso torna a tecnologia mais segura e confiável. Transparência: todas as transações registradas no Blockchain são públicas e podem ser consultadas por qualquer pessoa. Imutabilidade: uma vez registrado, um bloco não pode ser alterado ou excluído. O que são Criptomoedas? Criptomoedas são moedas digitais que usam a tecnologia Blockchain para registrar suas transações. Elas são descentralizadas, transparentes e imutáveis. As principais criptomoedas são: Bitcoin: a primeira e mais popular criptomoeda. Ethereum: uma plataforma de contratos inteligentes que também pode ser usada para criar criptomoedas. Tether: uma stablecoin atrelada ao dólar americano. Saiba mais...
Author: MAX EDITORIAL
Publisher: Max Editorial
ISBN: 1779716842
Category : Business & Economics
Languages : en
Pages : 69
Get Book Here
Book Description
O que é Blockchain? Blockchain é uma tecnologia de registro distribuído que permite a manutenção de uma base de dados segura e confiável. Ela é baseada em um sistema de blocos encadeados, cada um contendo um conjunto de informações. Esses blocos são protegidos por criptografia e distribuídos por uma rede de computadores. As principais características do Blockchain são: Descentralização: a rede Blockchain não é controlada por um único órgão ou entidade, mas por uma rede de computadores. Isso torna a tecnologia mais segura e confiável. Transparência: todas as transações registradas no Blockchain são públicas e podem ser consultadas por qualquer pessoa. Imutabilidade: uma vez registrado, um bloco não pode ser alterado ou excluído. O que são Criptomoedas? Criptomoedas são moedas digitais que usam a tecnologia Blockchain para registrar suas transações. Elas são descentralizadas, transparentes e imutáveis. As principais criptomoedas são: Bitcoin: a primeira e mais popular criptomoeda. Ethereum: uma plataforma de contratos inteligentes que também pode ser usada para criar criptomoedas. Tether: uma stablecoin atrelada ao dólar americano. Saiba mais...
Author: MAX EDITORIAL
Publisher: Max Editorial
ISBN: 1779717423
Category : Business & Economics
Languages : en
Pages : 56
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Book Description
Blockchain es una tecnología de contabilidad distribuida que permite el mantenimiento de una base de datos segura y confiable. Se basa en un sistema de bloques encadenados, cada uno de los cuales contiene un conjunto de información. Estos bloques están protegidos por criptografía y distribuidos a través de una red informática. Las principales características de Blockchain son: red Blockchain no está controlada por un único organismo o entidad, sino por una red de ordenadores. Esto hace que la tecnología sea más segura y confiable. Transparencia: todas las transacciones registradas en Blockchain son públicas y pueden ser consultadas por cualquier persona. Inmutabilidad: una vez registrado, un bloque no se puede cambiar ni eliminar. Aprende Mucho Más...
Author: Joy A. Cavagnaro
Publisher: CRC Press
ISBN: 1000471853
Category : Medical
Languages : en
Pages : 952
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Book Description
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Author: March Hoffman
Publisher:
ISBN:
Category : Feminism
Languages : en
Pages : 2
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Book Description
Author: Joy A. Cavagnaro
Publisher: John Wiley & Sons
ISBN: 1118679385
Category : Medical
Languages : en
Pages : 1012
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Book Description
"The goal is to provide a comprehensive reference book for the preclinicaldiscovery and development scientist whose responsibilities span target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for regulatory scientists whose responsibilities include the evaluation of novel therapies." —From the Afterword by Anthony D. Dayan Proper preclinical safety evaluation can improve the predictive value, lessen the time and cost of launching new biopharmaceuticals, and speed potentially lifesaving drugs to market. This guide covers topics ranging from lead candidate selection to establishing proof of concept and toxicity testing to the selection of the first human doses. With chapters contributed by experts in their specific areas, Preclinical Safety Evaluation of Biopharmaceuticals: A Science-Based Approach to Facilitating Clinical Trials: Includes an overview of biopharmaceuticals with information on regulation and methods of production Discusses the principles of ICH S6 and their implementation in the U.S., Europe, and Japan Covers current practices in preclinical development and includes a comparison of safety assessments for small molecules with those for biopharmaceuticals Addresses all aspects of the preclinical evaluation process, including: the selection of relevant species; safety/toxicity endpoints; specific considerations based upon class; and practical considerations in the design, implementation, and analysis of biopharmaceuticals Covers transitioning from preclinical development to clinical trials This is a hands-on, straightforward reference for professionals involved in preclinical drug development, including scientists, toxicologists, project managers, consultants, and regulatory personnel.
Author: Frederick P. Brooks (Jr.)
Publisher: Reading, Mass. ; Don Mills, Ont. : Addison-Wesley Publishing Company
ISBN:
Category : Computers
Languages : en
Pages : 216
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Book Description
The orderly Sweet-Williams are dismayed at their son's fondness for the messy pastime of gardening.
Author: Andrew Hunt
Publisher: Addison-Wesley Professional
ISBN: 013211917X
Category : Computers
Languages : en
Pages : 346
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Book Description
What others in the trenches say about The Pragmatic Programmer... “The cool thing about this book is that it’s great for keeping the programming process fresh. The book helps you to continue to grow and clearly comes from people who have been there.” — Kent Beck, author of Extreme Programming Explained: Embrace Change “I found this book to be a great mix of solid advice and wonderful analogies!” — Martin Fowler, author of Refactoring and UML Distilled “I would buy a copy, read it twice, then tell all my colleagues to run out and grab a copy. This is a book I would never loan because I would worry about it being lost.” — Kevin Ruland, Management Science, MSG-Logistics “The wisdom and practical experience of the authors is obvious. The topics presented are relevant and useful.... By far its greatest strength for me has been the outstanding analogies—tracer bullets, broken windows, and the fabulous helicopter-based explanation of the need for orthogonality, especially in a crisis situation. I have little doubt that this book will eventually become an excellent source of useful information for journeymen programmers and expert mentors alike.” — John Lakos, author of Large-Scale C++ Software Design “This is the sort of book I will buy a dozen copies of when it comes out so I can give it to my clients.” — Eric Vought, Software Engineer “Most modern books on software development fail to cover the basics of what makes a great software developer, instead spending their time on syntax or technology where in reality the greatest leverage possible for any software team is in having talented developers who really know their craft well. An excellent book.” — Pete McBreen, Independent Consultant “Since reading this book, I have implemented many of the practical suggestions and tips it contains. Across the board, they have saved my company time and money while helping me get my job done quicker! This should be a desktop reference for everyone who works with code for a living.” — Jared Richardson, Senior Software Developer, iRenaissance, Inc. “I would like to see this issued to every new employee at my company....” — Chris Cleeland, Senior Software Engineer, Object Computing, Inc. “If I’m putting together a project, it’s the authors of this book that I want. . . . And failing that I’d settle for people who’ve read their book.” — Ward Cunningham Straight from the programming trenches, The Pragmatic Programmer cuts through the increasing specialization and technicalities of modern software development to examine the core process--taking a requirement and producing working, maintainable code that delights its users. It covers topics ranging from personal responsibility and career development to architectural techniques for keeping your code flexible and easy to adapt and reuse. Read this book, and you'll learn how to Fight software rot; Avoid the trap of duplicating knowledge; Write flexible, dynamic, and adaptable code; Avoid programming by coincidence; Bullet-proof your code with contracts, assertions, and exceptions; Capture real requirements; Test ruthlessly and effectively; Delight your users; Build teams of pragmatic programmers; and Make your developments more precise with automation. Written as a series of self-contained sections and filled with entertaining anecdotes, thoughtful examples, and interesting analogies, The Pragmatic Programmer illustrates the best practices and major pitfalls of many different aspects of software development. Whether you're a new coder, an experienced programmer, or a manager responsible for software projects, use these lessons daily, and you'll quickly see improvements in personal productivity, accuracy, and job satisfaction. You'll learn skills and develop habits and attitudes that form the foundation for long-term success in your career. You'll become a Pragmatic Programmer.
Author: Carlos Garces-Restrepo
Publisher: Fao
ISBN:
Category : Business & Economics
Languages : en
Pages : 88
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Book Description
The present water report is the final product emanating from efforts by FAO, IWMI and others to document and understand the implications of the irrigation sector embarking on a wide reform process. It is intended to be a knowledge synthesis document that captures the global experiences emerging from a wide-reaching process targeting the reform of the irrigation sector. This study indicates that irrigation management transfer (IMT) is an approach for irrigation sector reform with the potential to improve the sustainability of irrigation systems. The process requires inter alia strong political commitment, negotiations among stakeholders, and long-term capacity development. Irrigation management transfer should not be seen as a process that has a clear "beginning" and "end". While the former can be more easily identified, the latter is much more difficult to determine. In fact, IMT can be the initial stage of an evolving long reform process. The accompanying CD-ROM contains IMT country profiles and case studies, an international IMT e-mail conference, a bibliography and links.--Publisher's description.
Author: Bill Gates
Publisher: Penguin Group
ISBN:
Category : Business & Economics
Languages : en
Pages : 356
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Book Description
In this clear-eyed, candid, and ultimately reassuring
Author: Jennifer Hecht
Publisher: Harper Collins
ISBN: 0061744891
Category : Social Science
Languages : en
Pages : 571
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Book Description
Jennifer Michael Hecht explodes the myths about happiness, liberating us from the message that there's only one way to care for our hearts, minds, and bodies.
