Combinatorics of Genome Rearrangements

Combinatorics of Genome Rearrangements PDF Author: Guillaume Fertin
Publisher: MIT Press
ISBN: 0262062828
Category : Combinatorial analysis
Languages : en
Pages : 305

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Book Description
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.

Combinatorics of Genome Rearrangements

Combinatorics of Genome Rearrangements PDF Author: Guillaume Fertin
Publisher: MIT Press
ISBN: 0262062828
Category : Combinatorial analysis
Languages : en
Pages : 305

Get Book Here

Book Description
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.

Computing and Combinatorics

Computing and Combinatorics PDF Author: Tandy Warnow
Publisher: Springer Science & Business Media
ISBN: 3540405348
Category : Computers
Languages : en
Pages : 573

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Book Description
The papers in this volume were presented at the 9th Annual International C- puting and Combinatorics Conference (COCOON 2003), held July 25–28, 2003, in Big Sky, MT, USA. The topics cover most aspects of theoretical computer science and combinatorics related to computing. Submissionstotheconferencethisyearwereconductedelectronically.Atotal of 114 papers were submitted, of which 52 were accepted. The papers were evaluated by an international program committee consisting of Nina Amenta, Tetsuo Asano, Bernard Chazelle, Zhixiang Chen, Francis Chin, Kyung-Yong Chwa, Robert Cimikowski, Anne Condon, Michael Fellows, Anna Gal, Michael Hallett,DanielHuson,NaokiKatoh,D.T.Lee,BernardMoret,BrendanMumey, Gene Myers, Hung Quang Ngo, Takao Nishizeki, Cindy Phillips, David Sanko?, Denbigh Starkey, Jie Wang, Lusheng Wang, Tandy Warnow and Binhai Zhu. It is expected that most of the accepted papers will appear in a more complete form in scienti?c journals. The submitted papers were from Canada (6), China (7), Estonia (1), F- land (1), France (1), Germany (8), Israel (4), Italy (1), Japan (11), Korea (22), Kuwait (1), New Zealand (1), Singapore (2), Spain (1), Sweden (2), Switzerland (3), Taiwan (7), the UK (1) and the USA (34). Each paper was evaluated by at least three Program Committee members, assisted in some cases by subre- rees. In addition to selected papers, the conference also included three invited presentations by Jon Bentley, Dan Gus?eld and Joel Spencer.

String Processing and Information Retrieval

String Processing and Information Retrieval PDF Author: Franco Maria Nardini
Publisher: Springer Nature
ISBN: 3031439805
Category : Computers
Languages : en
Pages : 409

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Book Description
This volume LNCS 14240 constitutes the refereed proceedings of the 30th International Symposium on String Processing and Information Retrieval, SPIRE 2023, held in Pisa, Italy, during September 26–28, 2023. The 31 full papers presented were carefully reviewed and selected from 47 submissions. They cover topics such as: data structures; algorithms; constrained Substring complexity; data compression codes; succinct k-spectra; and LCP array of wheeler DFAs.

Algorithms in Bioinformatics

Algorithms in Bioinformatics PDF Author: Ben Raphael
Publisher: Springer
ISBN: 364233122X
Category : Computers
Languages : en
Pages : 465

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Book Description
This book constitutes the refereed proceedings of the 12th International Workshop on Algorithms in Bioinformatics, WABI 2012, held in Ljubljana, Slovenia, in September 2012. WABI 2012 is one of six workshops which, along with the European Symposium on Algorithms (ESA), constitute the ALGO annual meeting and focuses on algorithmic advances in bioinformatics, computational biology, and systems biology with a particular emphasis on discrete algorithms and machine-learning methods that address important problems in molecular biology. The 35 full papers presented were carefully reviewed and selected from 92 submissions. The papers include algorithms for a variety of biological problems including phylogeny, DNA and RNA sequencing and analysis, protein structure, and others.

Models and Methods for Biological Evolution

Models and Methods for Biological Evolution PDF Author: Gilles Didier
Publisher: John Wiley & Sons
ISBN: 1394284241
Category : Science
Languages : en
Pages : 340

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Book Description
Biological evolution is the phenomenon concerning how species are born, are transformed or disappear over time. Its study relies on sophisticated methods that involve both mathematical modeling of the biological processes at play and the design of efficient algorithms to fit these models to genetic and morphological data. Models and Methods for Biological Evolution outlines the main methods to study evolution and provides a broad overview illustrating the variety of formal approaches used, notably including combinatorial optimization, stochastic models and statistical inference techniques. Some of the most relevant applications of these methods are detailed, concerning, for example, the study of migratory events of ancient human populations or the progression of epidemics. This book should thus be of interest to applied mathematicians interested in central problems in biology, and to biologists eager to get a deeper understanding of widely used techniques of evolutionary data analysis.

Issues in Applied Mathematics: 2013 Edition

Issues in Applied Mathematics: 2013 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1490108556
Category : Mathematics
Languages : en
Pages : 1183

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Book Description
Issues in Applied Mathematics / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Mathematical Physics. The editors have built Issues in Applied Mathematics: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Mathematical Physics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Applied Mathematics: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Comparative Genomics

Comparative Genomics PDF Author: Joao Meidanis
Publisher: Springer
ISBN: 3319679791
Category : Computers
Languages : en
Pages : 330

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Book Description
This book constitutes the proceedings of the 15th International Workshop Comparative Genomics, RECOMB-CG 2017, held in Barcelona, Spain, in October 2017. The 16 full papers presented were carefully reviewed and selected from 32 submissions. The papers report original research in all areas of Comparative Genomics.

Combinatorial Pattern Matching

Combinatorial Pattern Matching PDF Author: Alexander S. Kulikov
Publisher: Springer
ISBN: 3319075667
Category : Computers
Languages : en
Pages : 301

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Book Description
This book constitutes the refereed proceedings of the 25th Annual Symposium on Combinatorial Pattern Matching, CPM 2014, held in Moscow, Russia, in June 2014. The 28 revised full papers presented together with 5 invited talks were carefully reviewed and selected from 54 submissions. The papers address issues of searching and matching strings and more complicated patterns such as trees; regular expressions; graphs; point sets; and arrays. The goal is to derive combinatorial properties of such structures and to exploit these properties in order to achieve superior performance for the corresponding computational problems. The meeting also deals with problems in computational biology; data compression and data mining; coding; information retrieval; natural language processing; and pattern recognition.

Mathematical Software -- ICMS 2014

Mathematical Software -- ICMS 2014 PDF Author: Hoon Hong
Publisher: Springer
ISBN: 3662441993
Category : Computers
Languages : en
Pages : 762

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Book Description
This book constitutes the proceedings of the 4th International Conference on Mathematical Software, ICMS 2014, held in Seoul, South Korea, in August 2014. The 108 papers included in this volume were carefully reviewed and selected from 150 submissions. The papers are organized in topical sections named: invited; exploration; group; coding; topology; algebraic; geometry; surfaces; reasoning; special; Groebner; triangular; parametric; interfaces and general.

Algebraic Statistics for Computational Biology

Algebraic Statistics for Computational Biology PDF Author: L. Pachter
Publisher: Cambridge University Press
ISBN: 9780521857000
Category : Mathematics
Languages : en
Pages : 440

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Book Description
This book, first published in 2005, offers an introduction to the application of algebraic statistics to computational biology.