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Author: Guillaume Fertin
Publisher: MIT Press
ISBN: 0262062828
Category : Combinatorial analysis
Languages : en
Pages : 305
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Book Description
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.
Author: Guillaume Fertin
Publisher: MIT Press
ISBN: 0262062828
Category : Combinatorial analysis
Languages : en
Pages : 305
Get Book Here
Book Description
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.
Author:
Publisher:
ISBN: 9780262258180
Category : Combinatorial analysis
Languages : en
Pages : 288
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Book Description
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically orientated but offering biological explanations when required, this volume offers the first comprehensive survey of a rapidly expanding application of combinatorial optimization.
Author: Niklas Eriksen
Publisher:
ISBN:
Category :
Languages : en
Pages : 43
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Book Description
Author: Zheng Fu
Publisher:
ISBN:
Category : Gene mapping
Languages : en
Pages : 282
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Book Description
Author:
Publisher: Academic Press
ISBN: 0128144300
Category : Science
Languages : en
Pages : 610
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Book Description
Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts. Contributions by the leading experts in the field of DNA repair, recombination, replication and genome stability Documents cutting edge methods
Author: Xiaodong Hu
Publisher: Springer
ISBN: 3540697330
Category : Computers
Languages : en
Pages : 692
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Book Description
The refereed proceedings of the 14th Annual International Computing and Combinatorics Conference, COCOON 2008, held in Dalian, China, in June 2008. The 66 revised full papers presented were carefully reviewed and selected from 172 submissions. The papers are organized in topical sections on algorithms and data structures, algorithmic game theory and online algorithms, automata, languages, logic, and computability, combinatorics related to algorithms and complexity, complexity theory, cryptography, reliability and security, and database theory, computational biology and bioinformatics, computational algebra, geometry, and number theory, graph drawing and information visualization, graph theory and algorithms, communication networks, and optimization, wireless network, network optimization, and scheduling problem.
Author: Takao Asano
Publisher: Springer
ISBN: 3540486860
Category : Computers
Languages : en
Pages : 508
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Book Description
The abstracts and papers in this volume were presented at the Fifth Annual International Computing and Combinatorics Conference (COCOON ’99), which was held in Tokyo, Japan from July 26 to 28, 1999. The topics cover most aspects of theoretical computer science and combinatorics pertaining to computing. In response to the call for papers, 88 high-quality extended abstracts were submitted internationally, of which 46 were selected for presentation by the p- gram committee. Every submitted paper was reviewed by at least three program committee members. Many of these papers represent reports on continuing - search, and it is expected that most of them will appear in a more polished and complete form in scienti c journals. In addition to the regular papers, this v- ume contains abstracts of two invited plenary talks by Prabhakar Raghavan and Seinosuke Toda. The conference also included a special talk by Kurt Mehlhorn on LEDA (Library of E cient Data types and Algorithms). The Hao Wang Award (inaugurated at COCOON ’97) is given to honor the paper judged by the program committee to have the greatest scienti c merit. The recipients of the Hao Wang Award 1999 were Hiroshi Nagamochi and Tos- hide Ibaraki for their paper \An Approximation for Finding a Smallest 2-Edge- Connected Subgraph Containing a Speci ed Spanning Tree".
Author: Alexander S. Kulikov
Publisher: Springer
ISBN: 3319075667
Category : Computers
Languages : en
Pages : 301
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Book Description
This book constitutes the refereed proceedings of the 25th Annual Symposium on Combinatorial Pattern Matching, CPM 2014, held in Moscow, Russia, in June 2014. The 28 revised full papers presented together with 5 invited talks were carefully reviewed and selected from 54 submissions. The papers address issues of searching and matching strings and more complicated patterns such as trees; regular expressions; graphs; point sets; and arrays. The goal is to derive combinatorial properties of such structures and to exploit these properties in order to achieve superior performance for the corresponding computational problems. The meeting also deals with problems in computational biology; data compression and data mining; coding; information retrieval; natural language processing; and pattern recognition.
Author: Lingling Jin
Publisher: Springer Nature
ISBN: 3031062205
Category : Mathematics
Languages : en
Pages : 344
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Book Description
This book constitutes the refereed proceedings of the 19th Annual RECOMB Satellite Workshop on Comparative Genomics, RECOMB-CG which took place in La Jolla, USA, during May 20-21, 2022. The 18 full papers included in this book were carefully reviewed and selected from 28 submissions. The papers were organized in topical sections on evolution; phylogenetics; homology and reconciliation; genome rearrangements; metagenomics; and genomic sequencing.
Author: Mathieu Blanchette
Publisher: Springer
ISBN: 3030008347
Category : Computers
Languages : en
Pages : 325
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Book Description
This book constitutes the proceedings of the 16th International Conference on Comparative Genomics, RECOMB-CG 2018, held in Magog-Orford, QC, Canada, in October 2018. The 18 full papers presented were carefully reviewed and selected from 29 submissions. The papers cover topics such as: genome rearrangements; genome sequencing; applied comparative genomics; reconciliation and coalescence; and phylogenetics.
