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Author: H.Gerhard Vogel
Publisher: Springer Science & Business Media
ISBN: 3540898905
Category : Medical
Languages : en
Pages : 576
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Book Description
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Author: H.Gerhard Vogel
Publisher: Springer Science & Business Media
ISBN: 3540898905
Category : Medical
Languages : en
Pages : 576
Get Book Here
Book Description
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Author: Anne L. Peters
Publisher: American Diabetes Association
ISBN: 1580405061
Category : Medical
Languages : en
Pages : 729
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Book Description
The American Diabetes Association/JDRF Type 1 Diabetes Sourcebook serves as both an evidence-based reference work and consensus report outlining the most critical components of care for individuals with type 1 diabetes throughout their lifespan. The volume serves not only as a comprehensive guide for clinicians, but also reviews the evidence supporting these components of care and provides a perspective on the critical areas of research that are needed to improve our understanding of type 1 diabetes diagnosis and treatment. The volume focuses specifically on the needs of patients with type 1 diabetes and provides clear and detailed guidance on the current standards for the optimal treatment of type 1 diabetes from early childhood to later life. To accomplish the book’s editorial goals, Editors-in-Chief, Drs. Anne Peters and Lori Laffel, assembled an editorial steering committee of prominent research physicians, clinicians, and educators to develop the topical coverage. In addition, a Managing Editor was brought on to help the authors write and focus their chapters.
Author: Ashley W. Ells
Publisher: McGraw Hill Professional
ISBN: 0071815767
Category : Medical
Languages : en
Pages : 357
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Book Description
A STEP-BY-STEP GUIDE TO IMPLEMENTING ADVANCED PHARMACY SERVICES IN COMMUNITY AND CLINIC SETTINGS Community and Clinical Pharmacy Services teaches pharmacy students and practicing pharmacists how to provide advanced levels of pharmacy services in community and clinic settings designed to help patients achieve specific health goals and treat common disease states. This unique text provides practical--rather than merely ideological--ways for pharmacists to utilize their extensive clinical knowledge and fill a major gap in American health care. It discusses barriers, necessary skills, required knowledge, and issues related to preparation, interventions, patient outcomes, economic aspects, and marketing considerations for therapeutic areas commonly addressed in the outpatient setting. The beginning of the book delves into the general management skills necessary to provide and implement advanced patient care services, including documentation, patient interviewing, and medication therapy management. Important chapters discuss disease states that would most likely be amenable to development of pharmacy services, including: Asthma Smoking Cessation Diabetes Hypertension Osteoporosis Obesity Also covered are immunizations, anticoagulation, and cardiometabolic services. The disease state chapters include learning aids such as summary points, first-hand accounts from experienced pharmacists who have implemented pharmacy services for that particular condition, a simulated patient case, and multiple-choice questions.
Author: Barbara G. Wells
Publisher: McGraw Hill Professional
ISBN: 9780071433228
Category : Medical
Languages : en
Pages : 966
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Book Description
BONE AND JOINT DISORDERS Edited by Terry L. Schwinghammer 1. Gout and Hyperuricemia 2. Osteoarthritis 3. Osteoporosis 4. Rheumatoid Arthritis CARDIOVASCULAR DISORDERS Edited by Terry L. Schwinghammer 5. Arrhythmias 6. Cardiopulmonary Resuscitation 7. Heart Failure 8. Hyperlipidemia 9.
Author: Terry L. Schwinghammer
Publisher: McGraw-Hill Medical Publishing
ISBN:
Category : Medical
Languages : en
Pages : 484
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Book Description
This casebook is designed to help students develop the skills required to identify and resolve drug therapy problems through the use of patient case studies.
Author: Cecilia C. Low Wang
Publisher: American Diabetes Association
ISBN: 1580406777
Category : Medical
Languages : en
Pages : 253
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Book Description
Type 1 diabetes, formerly known as juvenile diabetes, is a complex disorder that requires a great deal of patient-guided self-care. In recent years, advances in diabetes treatment have dramatically shifted potential outcomes in the favor of the patient with diabetes. The challenge for health care professionals is to realize this potential through an individualized, flexible, and responsive treatment plan for patients with type 1 diabetes. Now in its seventh edition, Medical Management of Type 1 Diabetes offers health care providers the newest information and guidelines for the treatment of type 1 diabetes. Built on the foundation of multiple daily insulin injections and insulin pump therapy, this book guides health care providers in helping their patients continually strive for optimal blood glucose control. This new edition focuses on the latest molecular advances, new treatment methods, recent clinical trials, and the American Diabetes Association's Standards of Care. Key topics also include new insulins and administration protocols, advanced carbohydrate counting, and emphasis on continuing patient education. Individual sections address all of the topics in managing type 1 diabetes, including diagnosis and classification/pathogenesis, diabetes standards and education, tools of therapy, special situations, psychosocial factors affecting adherence, quality of life, and well-being and complications. Medical Management of Type 1 Diabetes is an essential addition to any clinician's library for the treatment and understanding of type 1 diabetes.
Author: Milo Gibaldi
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 196
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Book Description
Author: R. A. DeFronzo
Publisher: John Wiley & Sons
ISBN: 1118387678
Category : Medical
Languages : en
Pages : 1200
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Book Description
The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.
Author: John R. White
Publisher: American Diabetes Association
ISBN: 9781580407762
Category : Health & Fitness
Languages : en
Pages : 568
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Book Description
Medications for the Treatment of Diabetes offers a bridge between drug handbooks and pharmacology texts. Focusing entirely on diabetes drugs, this reference is divided into two sections: 1) Drugs used to manage hyperglycemia and 2) Management of diabetic co-morbidities. The first section includes: -- Pharmacologic Therapy for Type 1 Diabetes -- Management of Hyperglycemia in Type 1 DM- info from practical use of insulin, pathophysiology, treatment strategy -- Insulins- RAIAs, Short-acting insulins, intermediate-acting insulins, LAIAs, Concentrated Insulins, Insulin pumps and patches, inhaled insulins, mixed and mixing insulin, use in Type 1, use in Type 2 -- Pharmacologic Therapy for Type 2 Diabetes -- Management of Hyperglycemia in Type 2- brief overview, pathophysiology, treatment strategy, overview of medications -- Biguanides -- TZDs -- SUs -- Glinides -- SGLT-2 Inhibitors -- AGIs -- DPP-IV inhibitors -- GLP RAs -- Amylin mimetics -- BARs -- DA-2 agonists Each chapter in Section 1 includes: 1.Drug class overview and role in diabetes treatment 2.Pharmacology -- a. Mechanism of action, b. Pharmacokinetics 3.Treatment Advantages/Disadvantages -- a. General for the class, b.When applicable, a discussion of evidence that supports the benefits of using a particular drug in a class over another in the same class (eg, Avandia vs Actos) 4.Therapeutic Considerations -- a. Significant Warnings/Precautions, b. Special Populations, c. Pharmacogenomics, d. Adverse effects and monitoring, e. Drug Interactions, f. Dosage and administration 5.Table with Doses and Dose Adjustments 6.List of important combination products 7.References The second section includes: -- Cardiovascular Disease and Risk Management -- Microvascular Complications and Foot Care -- Medications for the Management of Hypertension -- Medications for the Management of Hyperlipidemia -- Antiplatelet Therapy -- Medications for Smoking Cessation -- Medications for the Management of Neuropathy (peripheral and autonomic) -- Medications for the Management of Nephropathy -- Medications for the Management of Retinopathy -- Medications for the Management of Depression -- Medications for the Management of Hypoglycemia -- Medications for the Management of Obesity -- Immunizations in Patients with Diabetes Each chapter in Section 2 includes: 1.An overview of the condition or problem 2.Goals of treatment 3.Overview of the medications and rationale for the medications used for the problem 4.Overview of each class of medication 5.Overview of combination therapy -- a. first combination, b. second combination 6.Doses and Dose Adjustments for the more salient medications 7.List of important combination products 8.References
Author: Dennis L. Kasper
Publisher: McGraw Hill Professional
ISBN: 1260455351
Category : Medical
Languages : en
Pages : 1277
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Book Description
All the authority of the most trusted brand in medical content in a convenient, portable guide A Doody's Core Titles for 2023! The Harrison’s Manual, derived from most clinically salient content featured in Harrison's Principles of Internal Medicine, 20th Edition, delivers numerous clinical algorithms in one practical, portable resource. The Manual also includes abundant quick reference tables, plus concise text—providing rapid access to bedside information when decisions need to be made quickly. This full color summary guide covers all diseases and conditions commonly seen in inpatient general medicine, so you can be sure to find invaluable content directly to your workflow and practice. The 20th edition has been updated to reflect the latest clinical developments in medicine. The Manual truly makes it easy to find what you need at the point of care. The easy-to-navigate chapters cover symptoms/signs, medical emergencies, specific diseases, and care of the hospitalized patient, with a particular focus on: Etiology and Epidemiology Clinically Relevant Pathophysiology Signs and Symptoms Differential Diagnosis Physical and Laboratory Findings Therapeutics Practice Guidelines, and more
