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Author: Franz H. Messerli
Publisher: Springer Science & Business Media
ISBN: 1461535166
Category : Medical
Languages : en
Pages : 592
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Book Description
That geriatric cardiology has become a science and clinical discipline in its own rights is beyond dispute. Most cardiac disorders present with different symptoms and signs, require a different diagnostic and therapeutic approach, and also have a different prognosis in the elderly as compared to younger patients. Cardiovascular Disease in the Elderly provides a comprehensive, up-to-date guide to the physician, representing a pioneering work in this increasingly complex area. For this third edition most of the chapters have been completely rewritten, some by different authors. Four new chapters have been added, dealing with cardiac transplantation, invasive cardiovascular procedures, dietary considerations and ethical considerations. It cannot be denied that invasive procedures and transplantation are highly controversial in this area, and the ethical dilemmas involved are ably discussed by Dr Davis and associates. All chapters are supplied with a thorough list of references, making this third edition of Cardiovascular Disease in the Elderly the most thorough, concise guide for the practicing physician.
Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290
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Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Author: Basil S. Lewis
Publisher: Springer Science & Business Media
ISBN: 3642582311
Category : Medical
Languages : en
Pages : 713
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Book Description
Following remarkable advances in medical care. the past decade has witnessed a significant improvement in the survival of patients with many different forms of heart disease. In the majority ofcases. however. the advances have been pa lIiative and not curative. The resu It has been the prod uction of an ever-increasing population of patients with heart disease. many of whom suffer from myocardial dysfunction and latent or overt heart failure. Heart failure is now a major cause of morbidity and mortality in cardiac patients. This book aims to combine in a single volume data relating to both pathophysiological mechanisms and the clinical management of the patient with heart failure. It includes chapters dealing with molecular. biochemical. and pathophysiological aspects of heart failure. ven tricular function and its assessment. and the clinical aspects of heart failure in different cardiac disorders, including ischemic heart disease. valvular heart disease. and the cardiomyopathies. There are sections on pharmacotherapy. the role of arrhythmias, exercise physiology. and neurohumoral mechanisms. The book also deals with newer inter ventional techniques. newer surgical procedures and some current problems relating to cardiac assist devices and heart and heart-lungs transplantation.
Author: Lionel H. Opie
Publisher: Springer Science & Business Media
ISBN: 1461308631
Category : Medical
Languages : en
Pages : 315
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Book Description
Calcium antagonists are now regarded as the most important advance in cardiac drug therapy since the advent of beta-adrenergic blocking agents. Acting ba sically as vasodilators-though with many other com plex mechanisms especially in the case of the anti arrhythmic calcium antagonists, these agents have grown in importance to become among the therapeutic agents of first choice for angina pectoris and hyper tension. The major aim of the present book is to present the clinician with the information needed for the practical use of calcium antagonists. What do all the numerous and often conflicting trials say? Do these agents really work? If so, which agent and in what dose? How do the three front runners, verapamil, nifedipine and diltia zem compare in the efficacy and side-effects with each other? How do the new second generation agents, now entering the North American market, slot in and com pare with the three first-liners? When the gloss is taken away from the advertisements, what is really left? The strong clinical bias of the present book should be complimented by further reading of books slanted towards fundamentals. One of the most important and recent of these is that by Dr Winifred Nayler (Calcium Antagonists, Academic Press, 1988). That book should be basic for essential background knowledge in the area of calcium antagonists. The important basic contribu tions of Fleckenstein deserve emphasis.
Author: Franz H. Messerli
Publisher: Springer Science & Business Media
ISBN: 1461535166
Category : Medical
Languages : en
Pages : 592
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Book Description
That geriatric cardiology has become a science and clinical discipline in its own rights is beyond dispute. Most cardiac disorders present with different symptoms and signs, require a different diagnostic and therapeutic approach, and also have a different prognosis in the elderly as compared to younger patients. Cardiovascular Disease in the Elderly provides a comprehensive, up-to-date guide to the physician, representing a pioneering work in this increasingly complex area. For this third edition most of the chapters have been completely rewritten, some by different authors. Four new chapters have been added, dealing with cardiac transplantation, invasive cardiovascular procedures, dietary considerations and ethical considerations. It cannot be denied that invasive procedures and transplantation are highly controversial in this area, and the ethical dilemmas involved are ably discussed by Dr Davis and associates. All chapters are supplied with a thorough list of references, making this third edition of Cardiovascular Disease in the Elderly the most thorough, concise guide for the practicing physician.
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 850
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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author: Jeffrey D. Hosenpud
Publisher: Lippincott Williams & Wilkins
ISBN: 0781762855
Category : Medical
Languages : en
Pages : 1487
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Book Description
Written by recognized leaders in the field, Congestive Heart Failure, Third Edition is a comprehensive, state-of-the-art reference on all basic and clinical aspects of heart failure. Coverage includes an entire section on pharmacologic therapy and a twenty-chapter section on clinical approaches to acute and chronic heart failure. This edition has new chapters on impact and treatment of comorbidities, prevention of sudden cardiac death, rationale for use of anticoagulants, ultrafiltration, use of mechanical devices, and gene and cell therapy. Readers will find up-to-date information on genetics, surgical therapies, ventricular synchronization, defibrillator therapy, mechanical approaches to atrial fibrillation, left ventricular assist devices, ventricular support and ventricular remodeling surgery, and myocardial regeneration/cell transplantation.
Author: Dr. Meenakshisundaram Sundaram Ramachandran
Publisher: Elsevier
ISBN: 0124165990
Category : Science
Languages : en
Pages : 668
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Book Description
The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. - Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins - Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail - Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging - Enables you to manage multiple clinical cases of cardiovascular toxicity - Outlined conclusions at the end of each chapter providing "key learning points to help you organize the chapter's details without losing insight
Author: H. K. Chopra
Publisher: JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
ISBN: 9350908034
Category : Medical
Languages : en
Pages : 805
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Book Description
Performedin the cardiac catheterization laboratory is also included in this section. The next section deals with all aspects of cardiac surgery. Surgery for ischemic heart disease, valve surgery, aortic surgery, robotically assisted cardiac surgery, surgery for congenital heart disease and cardiac transplantation are covered by well-known experts. The last section points to expected refinements and future developments in cardiology, such as stem cell therapy, newer thrombolytics, new frontiers in balloon valvotomy and cardiac transplantation and artificial hearts. This book includes more than 300 full coloured images and illustration. It can be used as a reference book in every library, hospitals, medical colleges and research institutions.
Author: Albert I Wertheimer
Publisher: CRC Press
ISBN: 9780789015853
Category : Medical
Languages : en
Pages : 232
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Book Description
Get a healthy perspective on pharmaceutical economics! Strategies in Pharmacoeconomics and Outcomes Research presents a comprehensive introduction to the economic aspects of the health sector, focusing on strategies for the development and marketing of healthcare products. A much-needed addition to this relatively new field, the book narrows health economics into the sub-discipline of pharmacoeconomics, bridging the gap between different interest groups in the pharmaceutical industry-research and development at one end, sales and marketing at the other. Using basic terminology and practical examples with descriptive tables and figures, it analyzes the implications of projecting costs of pharmaceutical products as a method of determining the viability of their development. Written from an international perspective, Strategies in Pharmacoeconomics and Outcomes Research examines the costs of drug therapy on health care systems and society through global marketing and modeling strategies, including clinical research and trial examples. Through the interlinked concepts of clinical research, outcomes research and pharmacoeconomics, the book evaluates the effectiveness of health technologies under “real world” circumstances or “normal” medical practice to achieve the optimum benefit from the resources available. The research process follows the economics of a drug?s efficacy (how it works under ideal circumstances) to its effectiveness (how it does in “real” life) to its efficiency (how cost-effective it is) in determining the baseline effects of a disease on economic and humanistic parameters. Strategies in Pharmacoeconomics and Outcomes Research also examines: resources and cost benefits (direct, indirect, intangible, and quality of life) health economical models (decision-tree analysis, Markov-model) reimbursement differences between countries due to the rate of currency exchange drug monitoring and regulation . . . and includes an extensive glossary! At a time when health economics has become increasingly important, Strategies in Pharmacoeconomics and Outcomes Research is an essential tool for the pharmaceutical, diagnostic, and medical device industries to ensure the most efficient use of limited resources. The book?s practical tone and common-sense methods provide a realistic approach that will benefit pharmaceutical and medical professionals, product managers, business development managers, drug regulatory affairs officials, and clinical study coordinators in making strategic and operational decisions about pharmaceutical development, production, or consumption.
Author: Winifred G. Nayler
Publisher: Springer Science & Business Media
ISBN: 364278223X
Category : Medical
Languages : en
Pages : 281
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Book Description
"Those who choose to increase their knowledge still further by reading ... will discover an exciting new world. " NOEL WHITTAKER, in "Making Money Made Simple" 1989. The development of calcium antagonists has recently been described as representing "one of the major advances in cardiovascular thera peutics of the latter half of the twentieth century" (Braunwald, 1990). However, although the development of these drugs started in the mid nineteen sixties it is only recently that their real potential has begun to be appreciated. Even now the calcium antagonist saga is not complete, since new compounds continue to appear and new therapeutic applica tions emerge. Based on the experience gained in the clinics in which these drugs have been used recognition is being given now to the need to improve upon the prototypes of the group. Such improvement is resulting in the development and production not only of long-acting formulations of the prototypes (nifedipine, verapamil and diltiazem) but also of new calcium antagonists with improved tissue selectivity, potency and duration of action. To those of us who are interested in this field such a development is both exciting and rewarding. As far as the clinicians who prescribe these drugs are concerned the long-acting nature of some of the newer calcium antagonists should make the satisfactory management of their patients an achievable goal.
