Author: Bauke de Jong
Publisher:
ISBN:
Category :
Languages : en
Pages : 80
Book Description
Chinese Hamster Lymphocyte Cultures
Author: Bauke de Jong
Publisher:
ISBN:
Category :
Languages : en
Pages : 80
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 80
Book Description
Some Inherited Porperties of Irradiated Chinese Hamster Cells in Culture
Author: Andrew B. Hellewell
Publisher:
ISBN:
Category :
Languages : en
Pages : 96
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 96
Book Description
Genetic Implications of Freezing Tolerance in Chinese Hamster Cells in Culture
Author: Colonious Knight
Publisher:
ISBN:
Category : Cold
Languages : en
Pages : 53
Book Description
Publisher:
ISBN:
Category : Cold
Languages : en
Pages : 53
Book Description
Production of Biologicals from Animal Cells in Culture
Author: R. E. Spier
Publisher: Butterworth-Heinemann
ISBN: 1483165159
Category : Medical
Languages : en
Pages : 853
Book Description
Production of Biologicals from Animal Cells in Culture reviews the state of the art in animal cell biotechnology, with emphasis on the sequence of events that occur when generating a biological from animal cells in culture. Methods that enable adjustment of nutrient feed streams into perfusion bioreactors so as to increase productivity are described. A number of issues are also addressed, such as the usefulness of the fingerprint method for cell characterization. Comprised of 135 chapters, this book begins with an overview of the problems and benefits of animal cell culture, followed by a discussion on the isolation of immortal murine macrophage cell lines. The reader is systematically introduced to the use of DNA fingerprinting to characterize cell banks; immortalization of cells with oncogenes; lipid metabolism of animal cells in culture; and energetics of glutaminolysis. Subsequent chapters explore serum-free and protein-free media; the physiology of animal cells; gene expression in animal cell systems; and animal cell bioreactors. The monitoring and assay of animal cell parameters are also considered, along with downstream processing and regulatory issues. This monograph will be of interest to students, practitioners, and investigators in the fields of microbiology and biotechnology.
Publisher: Butterworth-Heinemann
ISBN: 1483165159
Category : Medical
Languages : en
Pages : 853
Book Description
Production of Biologicals from Animal Cells in Culture reviews the state of the art in animal cell biotechnology, with emphasis on the sequence of events that occur when generating a biological from animal cells in culture. Methods that enable adjustment of nutrient feed streams into perfusion bioreactors so as to increase productivity are described. A number of issues are also addressed, such as the usefulness of the fingerprint method for cell characterization. Comprised of 135 chapters, this book begins with an overview of the problems and benefits of animal cell culture, followed by a discussion on the isolation of immortal murine macrophage cell lines. The reader is systematically introduced to the use of DNA fingerprinting to characterize cell banks; immortalization of cells with oncogenes; lipid metabolism of animal cells in culture; and energetics of glutaminolysis. Subsequent chapters explore serum-free and protein-free media; the physiology of animal cells; gene expression in animal cell systems; and animal cell bioreactors. The monitoring and assay of animal cell parameters are also considered, along with downstream processing and regulatory issues. This monograph will be of interest to students, practitioners, and investigators in the fields of microbiology and biotechnology.
Variation, Senescence, and Neoplasia in Cultured Somatic Cells
Author: John W. Littlefield
Publisher: Harvard University Press
ISBN: 9780674932081
Category : Aging
Languages : en
Pages : 186
Book Description
Aging and cancer may be manifestations of genetic, or epigenetic, changes in somatic cells. Through research, laboratory analysis of these related processes has become possible. Cells can be removed from the body, kept warm in laboratory glassware, nourished by artificial solutions, and studied for years, or even decades. Two types of cultures have emerged: Primary cultures, grown from cells obtained directly from living animals, may grow well for generations, but ultimately cease to divide. Established cultures, on the other hand, may grow and divide indefinitely. It is a striking fact that most, if not all, established cultures consist of cells that are heteroploid, having an abnormal chromosome complement that may include structural rearrangements as well as abnormalities of chromosome number. Most established cultures are also neoplastic on behavior and morphology--in this, they resemble cancers--and established cultures are, in fact, often grown from cancer cells. Interest in the role of chromosomes in neoplasia has recently been overshadowed by an emphasis on tumor viruses. This book should reawaken the former interest. It will also arouse new interest in the role of epigenetic mechanisms of animal cells, in contrast to the classic genetic processes. As Dr. John Littlefield writes: "The relationship between the overcoming of senescence, the appearance of heteroploidy, and the acquisition of neoplastic qualities is not yet clear, but it is of such great theoretical and practical importance as to demand attention and new ideas."
Publisher: Harvard University Press
ISBN: 9780674932081
Category : Aging
Languages : en
Pages : 186
Book Description
Aging and cancer may be manifestations of genetic, or epigenetic, changes in somatic cells. Through research, laboratory analysis of these related processes has become possible. Cells can be removed from the body, kept warm in laboratory glassware, nourished by artificial solutions, and studied for years, or even decades. Two types of cultures have emerged: Primary cultures, grown from cells obtained directly from living animals, may grow well for generations, but ultimately cease to divide. Established cultures, on the other hand, may grow and divide indefinitely. It is a striking fact that most, if not all, established cultures consist of cells that are heteroploid, having an abnormal chromosome complement that may include structural rearrangements as well as abnormalities of chromosome number. Most established cultures are also neoplastic on behavior and morphology--in this, they resemble cancers--and established cultures are, in fact, often grown from cancer cells. Interest in the role of chromosomes in neoplasia has recently been overshadowed by an emphasis on tumor viruses. This book should reawaken the former interest. It will also arouse new interest in the role of epigenetic mechanisms of animal cells, in contrast to the classic genetic processes. As Dr. John Littlefield writes: "The relationship between the overcoming of senescence, the appearance of heteroploidy, and the acquisition of neoplastic qualities is not yet clear, but it is of such great theoretical and practical importance as to demand attention and new ideas."
Nuclear Science Abstracts
Author:
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 744
Book Description
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 744
Book Description
Gene Expression and Regulation in Cultured Cells
Author: Katherine K. Sanford
Publisher:
ISBN:
Category : Cell Transformation, Viral
Languages : en
Pages : 420
Book Description
Publisher:
ISBN:
Category : Cell Transformation, Viral
Languages : en
Pages : 420
Book Description
Cancer Chemotherapy Reports
Author:
Publisher:
ISBN:
Category : Antineoplastic agents
Languages : en
Pages : 356
Book Description
Publisher:
ISBN:
Category : Antineoplastic agents
Languages : en
Pages : 356
Book Description
Cumulated Index Medicus
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1220
Book Description
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1220
Book Description
Journal of the National Cancer Institute
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 260
Book Description
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 260
Book Description