Chemometric Methods in Molecular Design PDF Download
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Author: Han van de Waterbeemd
Publisher: John Wiley & Sons
ISBN: 352761544X
Category : Science
Languages : en
Pages : 379
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Book Description
The statistical analysis of experimental and theoretical data lies at the heart of modern drug design. This practice-oriented handbook is a comprehensive account of modern chemometric methods in molecular design. It presents strategies for making more rational choices in the planning of syntheses, and describes techniques for analyzing biological and chemical data. Written by the world's experts, it provides in-depth information on * molecular concepts * experimental design in the planning of syntheses * multivariate analysis of chemical and biological data * statistical validation of QSAR results An additional benefit: the book contains a critical survey of commercially available software packages both for statistical analysis as well as for special applications. Industrial and academic researches in medicinal chemistry and organic chemistry will value this book as a useful source of information for their daily work. Also available: Advanced Computer-Assisted Techniques in Drug Discovery, edited by H. van de Waterbeemd
Author: Han van de Waterbeemd
Publisher: John Wiley & Sons
ISBN: 352761544X
Category : Science
Languages : en
Pages : 379
Get Book Here
Book Description
The statistical analysis of experimental and theoretical data lies at the heart of modern drug design. This practice-oriented handbook is a comprehensive account of modern chemometric methods in molecular design. It presents strategies for making more rational choices in the planning of syntheses, and describes techniques for analyzing biological and chemical data. Written by the world's experts, it provides in-depth information on * molecular concepts * experimental design in the planning of syntheses * multivariate analysis of chemical and biological data * statistical validation of QSAR results An additional benefit: the book contains a critical survey of commercially available software packages both for statistical analysis as well as for special applications. Industrial and academic researches in medicinal chemistry and organic chemistry will value this book as a useful source of information for their daily work. Also available: Advanced Computer-Assisted Techniques in Drug Discovery, edited by H. van de Waterbeemd
Author: Han van de Waterbeemd
Publisher: Wiley-VCH
ISBN:
Category : Health & Fitness
Languages : en
Pages : 388
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Book Description
Edited by R. Mannhold, P. Krogsgaard-Larsen, H. Timmerman Chemometric Methods in Molecular Design Edited by Han van de Waterbeemd Volume 2 The statistical analysis of experimental and theoretical data lies at the heart of modern drug design. This practice-oriented handbook is a comprehensive account of modern chemometric methods in molecular design. It presents strategies for making more rational choices in the planning of syntheses, and describes techniques for analyzing biological and chemical data. Written by the world's experts, it provides in-depth information on molecular concepts experimental design in the planning of syntheses multivariate analysis of chemical and biological data statistical validation of QSAR results An additional benefit: the book contains a critical survey of commercially available software packages both for statistical analysis as well as for special applications. Industrial and academic researches in medicinal chemistry and organic chemistry will value this book as a useful source of information for their daily work. Also available: Advanced Computer-Assisted Techniques in Drug Discovery, edited by H. van de Waterbeemd.
Author: Megh R. Goyal
Publisher: CRC Press
ISBN: 1351790617
Category : Science
Languages : en
Pages : 240
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Book Description
With a roster of international contributors, this volume offers an abundance of solutions to address agricultural water management challenges in today’s water-scarce areas of the world. The authors present studies on farmer-friendly irrigation scheduling methods, model-based analysis of crop water requirements, ways to optimize surface irrigation systems, and hydraulic design and management of surface water systems. The book goes on to highlight ways to improve soil properties by taking into account spatial, temporal, and spectral variability in soil properties. The volume also covers various innovative research studies on soil and water productivity of vegetable cultivation under water-stressed areas, application of coir geotextiles, and the role of biofertilizers in controlling soil degradation and maintaining fertile topsoil. Crop management strategies to enhance the efficient use of marginal and saline lands for nonconventional crops are also discussed. The book is divided into four sections, covering: engineering interventions in irrigation management technological interventions in management of soil properties technological inventions for soil and water conservation crop management for non-conventional use This volume will serve as an invaluable resource for academicians, researchers, engineers, agronomists, extension officers, students, and farmers in the broad discipline of agricultural and biological engineering.
Author: Toshio Morikawa
Publisher: MDPI
ISBN: 303897174X
Category : Science
Languages : en
Pages : 467
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Book Description
This book is a printed edition of the Special Issue "Biological Activity of Natural Secondary Metabolite Products" that was published in IJMS
Author: Munish Puri
Publisher: Academic Press
ISBN: 0128017449
Category : Computers
Languages : en
Pages : 442
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Book Description
Artificial Neural Network for Drug Design, Delivery and Disposition provides an in-depth look at the use of artificial neural networks (ANN) in pharmaceutical research. With its ability to learn and self-correct in a highly complex environment, this predictive tool has tremendous potential to help researchers more effectively design, develop, and deliver successful drugs. This book illustrates how to use ANN methodologies and models with the intent to treat diseases like breast cancer, cardiac disease, and more. It contains the latest cutting-edge research, an analysis of the benefits of ANN, and relevant industry examples. As such, this book is an essential resource for academic and industry researchers across the pharmaceutical and biomedical sciences. - Written by leading academic and industry scientists who have contributed significantly to the field and are at the forefront of artificial neural network (ANN) research - Focuses on ANN in drug design, discovery and delivery, as well as adopted methodologies and their applications to the treatment of various diseases and disorders - Chapters cover important topics across the pharmaceutical process, such as ANN in structure-based drug design and the application of ANN in modern drug discovery - Presents the future potential of ANN-based strategies in biomedical image analysis and much more
Author: Mahmud Tareq Hassan Khan
Publisher: Bentham Science Publishers
ISBN: 1608053792
Category : Science
Languages : en
Pages : 407
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Book Description
Quantitative Structure-Activity Relationship (QSAR) is a field where true multidisciplinary approaches are being used. This volume titled Recent Trends on QSAR in the Pharmaceutical Perceptions offers an overview on the latest advancements in the field.
Author: Romualdo Benigni
Publisher: CRC Press
ISBN: 0203010825
Category : Medical
Languages : en
Pages : 302
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Book Description
Applied with success in a number of areas, QSAR studies have become particularly popular in the rational design of drugs and pesticides. Much has been published on the principles of QSAR in this area, but not on their application s to toxic chemicals. This book provides the first comprehensive, interdisciplinary presentation of QSAR studies on
Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 588
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Book Description
Author: Han van de Waterbeemd
Publisher: John Wiley & Sons
ISBN: 3527615660
Category : Science
Languages : en
Pages : 363
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Book Description
The use of powerful computers has revolutionized molecular design and drug discovery. Thoroughly researched and well-structured, this comprehensive handbook covers highly effective and efficient techniques in 3D-QSAR and advanced statistical analysis. The emphasis is on showing users how to apply these methods and avoid costly and time-consuming methodical errors. Topics covered include * combination of statistical methods and molecular modeling tools * rational use of databases * advanced statistical techniques * neural networks and expert systems in molecular design This book addresses the practitioner in industry and research, as well as the novice wishing to become acquainted with modern tools in medicinal chemistry.
Author: Camille Georges Wermuth
Publisher: Academic Press
ISBN: 0080568777
Category : Medical
Languages : en
Pages : 982
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Book Description
The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry.NEW TO THIS EDITION: * Focus on chemoinformatics and drug discovery * Enhanced pedagogical features* New chapters including: - Drug absorption and transport - Multi-target drugs* Updates on hot new areas: NEW! Drug discovery and the latest techniques NEW! How potential drugs can move through the drug discovery/ development phases more quickly NEW! Chemoinformatics
