Author: David M. Jacobowitz
Publisher: CRC Press
ISBN: 1040212905
Category : Medical
Languages : en
Pages : 338
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Book Description
Representing the state-of-the-art in neurochemical mapping, Chemoarchitectonic Atlas of the Developing Mouse Brain provides a complete, full-color look at the developing mouse brain. Hundreds of coronal sections are presented, clearly illustrating structures at progressive stages of brain development.
Author: George Paxinos
Publisher: Academic Press
ISBN: 9780123742384
Category : Science
Languages : en
Pages : 0
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Book Description
For over two decades, Paxinos and Watson's The Rat Brain in Stereotaxic Coordinates, now in its 6th edition, and Franklin and Paxinos' The Mouse Brain in Stereotaxic Coordinates, now in its 3rd edition, have been the most used neuroanatomy references for neuroscientists. Both the illustrations and nomenclature of the atlas have become standard tools used by almost all research neuroscientists who deal with anatomy, physiology, or function. This new atlas represents the first time an accurate histochemical atlas showing the areas of the mouse brain in microscopic slides in a variety of different stains has been available. Until now researchers studying the mouse brain have been forced to consult the existing histochemical atlases of the rat brain (including Paxinos and Watson's) and extrapolate from rat data - a strategy which is not very accurate and often not successful. This atlas collects systematic images of the mouse brain stained with a range of key chemical markers to complement The Mouse Brain in Stereotaxic Coordinates.
Author: George Paxinos
Publisher: Academic Press
ISBN: 0128189630
Category : Medical
Languages : en
Pages : 602
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Book Description
The complement to The Rat Brain in Stereotaxic Coordinates, Chemoarchitectonic Atlas of the Rat Brain, Third Edition, features a single brain series of high-quality plates stained with eight different markers, extensively annotated and labelled throughout. Plates from the previous edition of Chemoarchitectonic Atlas of the Rat Brain have been re-scanned at high resolution and are shown in color. Labeled structures have been revised, corrected, and updated, providing users with a streamlined, up-to-date, and highly accurate compendium of chemical markers. Researchers with a need to understand the detailed organization of the rat brain as well as structure/function relationships will need this atlas and its array of stains. - Provides an archive of chemical markers in the rat brain used in many areas of research - Discusses primary data to help researchers identify structures in their own preparations from neuroanatomical, physiological, neuropharmacological, and gene expression studies - Accompanies the gold standard reference on the neuroanatomy of the nervous system of the most important model animal in neuroscience and experimental psychology - Covers both the rat forebrain and the rat brainstem - Thoroughly revised identification of structures following the new data from The Rat Brain in Stereotaxic Coordinates 7th edition and the Chick Brain in Stereotaxic Coordinates 2nd edition - Includes the Expert Consult eBook version, compatible with PC, Mac, and most mobile devices and eReaders, which allows readers to browse, search, and interact with content
Author: David M. Jacobowitz
Publisher: CRC Press
ISBN: 9780849326677
Category : Medical
Languages : en
Pages : 338
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Book Description
Representing the state-of-the-art in neurochemical mapping, Chemoarchitectonic Atlas of the Developing Mouse Brain provides a complete, full-color look at the developing mouse brain. Hundreds of coronal sections are presented, clearly illustrating structures at progressive stages of brain development.
Author: Kadharbatcha S. Saleem
Publisher: Academic Press
ISBN: 0123850878
Category : Medical
Languages : en
Pages : 402
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Book Description
A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates, Second Edition maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This edition of the atlas is unlike anything else available as it includes the detailed cyto- and chemoarchitectonic delineations of the brain areas in all three planes of sections (horizontal, coronal, and sagittal) that are derived from the same animal. This is a significant progress because in functional imaging studies, such as fMRI, both the horizontal and sagittal planes of sections are often the preferred planes given that multiple functionally active regions can be visualized simultaneously in a single horizontal or sagittal section. This combined MRI and histology atlas is designed to provide an easy-to-use reference for anatomical and physiological studies in macaque monkeys, and in functional-imaging studies in human and non-human primates using fMRI and PET. The first rhesus monkey brain atlas with horizontal, coronal, and sagittal planes of sections, derived from the same animal Shows the first detailed delineations of the cortical and subcortical areas in horizontal, coronal, and sagittal plane of sections in the same animal using different staining methods Horizonal series illustrates the dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographic sections matched with 47 detailed diagrams (Chapter 3) Coronal series presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographic sections, with 76 corresponding drawings (Chapter 4) Sagittal series shows the complete mediolateral extent of the left hemisphere in 30 sagittal MRI sections, with 30 corresponding drawings (Chapter 5). The sagittal series also illustrates the location of different fiber tracts in the white matter Individual variability - provides selected cortical and subcortical areas in three-dimensional MRI (horizontal, coronal, and sagittal MRI planes). For comparison, it also provides similar areas in coronal MRI section in six other monkeys. (Chapter 6) Vasculature - indicates the corresponding location of all major blood vessels in horizontal, coronal, and sagittal series of sections Provides updated information on the cortical and subcortical areas, such as architectonic areas and nomenclature, with references, in chapter 2 Provides the sterotaxic grid derived from the in-vivo MR image
Author: George Paxinos
Publisher: Academic Press
ISBN: 0125476221
Category : Science
Languages : en
Pages : 378
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Book Description
This atlas provides an accurate and detailed depiction of all brain structures at fetal stage E17.5, Day of birth, and Day 6 postnatal. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs. It is an indispensable guide for the interpretation of nervous system changes in gene knockout and transgenic mice. Contains: 43 photographs and drawings of Nissl-stained coronal sections of the brain of a fetal mouse at E17.5 days, 65 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse on the day of birth, and 73 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse aged 6 days postnatal. The drawings are based on the study of sections stained with Nissl and a range of neuroactive substances. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs.
Author: George Paxinos
Publisher: Academic Press
ISBN: 0124173179
Category : Science
Languages : en
Pages : 225
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Book Description
MRI/DTI Atlas of the Rat Brain offers two major enhancements when compared with earlier attempts to make MRI/DTI rat brain atlases. First, the spatial resolution at 25μm is considerably higher than previous data published. Secondly, the comprehensive set of MRI/DTI contrasts provided has enabled the authors to identify more than 80% of structures identified in The Rat Brain in Stereotaxic Coordinates. - Ninety-six coronal levels from the olfactory bulb to the pyramidal decussation are depicted - Delineations primarily made on the basis of direct observations on the MRI contrasts - Each of the 96 open book pages displays four items— top left, the directionally colored fractional anisotropy image derived from DTI (DTI - FAC); top right, the diffusion-weighted image (DWI); bottom left, the gradient recalled echo (GRE); and bottom right, a diagrammatic synthesis of the information derived from these three images plus two additional images, which are not displayed (ARDC and RD). This is repeated for 96 coronal levels, which makes the levels 250 μm apart - The FAC images are shown in full color - The orientation of sections corresponds to that in Paxinos and Watson's The Rat Brain in Stereotaxic Coordinates, 7th Edition (2014) - The images have been obtained from 3D isotropic population averages (number of rats=5). All abbreviations of structure names are identical to the Paxinos & Watson histologic atlas
Author: Hannsjörg Schröder
Publisher: Springer Nature
ISBN: 3030198987
Category : Medical
Languages : en
Pages : 353
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Book Description
This textbook describes the basic neuroanatomy of the laboratory mouse. The reader will be guided through the anatomy of the mouse nervous system with the help of abundant microphotographs and schemata. Learning objectives and summaries of key facts at the beginning of each chapter provide the reader with an overview on the most important information. As transgenic mice are one of the most widely used paradigms when it comes to modeling human diseases, a basic understanding of the neuroanatomy of the mouse is of considerable value for all students and researchers in the neurosciences and pharmacy, but also in human and veterinary medicine. Accordingly, the authors have included, whenever possible, comparisons of the murine and the human nervous system. The book is intended as a guide for all those who are about to embark on the structural, histochemical and functional phenotyping of the mouse’s central nervous system. It can serve as a practical handbook for students and early researchers, and as a reference book for neuroscience lectures and laboratories.
Author: Brad Bolon
Publisher: CRC Press
ISBN: 1420070096
Category : Medical
Languages : en
Pages : 446
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Book Description
Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology expe
Author: Paul C. Guest
Publisher: Springer
ISBN: 9783319524788
Category : Science
Languages : en
Pages : 0
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Book Description
Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.
