Disposition of Toxic Drugs and Chemicals in Man PDF Download
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Author: Randall C. Baselt
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 826
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Book Description
Author: Randall C. Baselt
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 826
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Book Description
Author: Dominic Milton Trott
Publisher:
ISBN: 9780995593619
Category :
Languages : en
Pages :
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Book Description
This is the full colour coffee table edition of The Honest Drug Book, with dimensions of 8.5" x 11" (21.59 x 27.94 cm). Produced to do justice to the hundreds of photographs, it also allows a more leisurely perusal of the contents. The Honest Drug Book presents the hidden truth about a topic which touches the lives of almost everyone. It cuts through the blustering rhetoric of the war on drugs, and documents the facts about the subject in general, and about the individual drugs specifically. This is a journey through 140 psychoactives, both chemical and botanical, each of which was personally tested and used by the author. For every drug, it lists the fundamental and sometimes life-critical information, including the anticipated onset, the common threshold doses, and the expected period of efficacy. It also describes the subjective experience: what the drug was actually like at each stage of the duration. These 'trip reports' are vital, as they help to identify pitfalls and specific risks for each substance. Often, this is achieved in a humorous and anecdotal manner, which is occasionally accentuated by the fact that the author had to travel the world to undertake the experiments lawfully. In addition to these often rich and lengthy reports, the book is crammed with data and general information, inclusive of legal briefings, relative harm tables, addiction and overdose advice, detailed reference material, and even a drug dictionary. Of critical importance is the first section, as it introduces the basics of harm reduction, in the form of a 10 step procedure to help mitigate risk. The same section explains core safety issues, such as how to test and identify a drug, and how to properly establish a dose. The book itself is lavishly illustrated with hundreds of photographs, including of the drugs themselves. The images in the botanical section also encompass some of the indigenous settings encountered on the journey. The full gamut of psychoactive chemicals and botanicals is covered. The well known include: LSD, heroin, cannabis, mephedrone, kratom, cocaine, 2C-B, DMT, yopo, methamphetamine, salvia divinorum, ketamine, ayahuasca and MDMA. The lesser known include: betel nut, 4-ho-met, changa, TPA, 4F-MPH, ephenidine, ololiuqui, cebil seeds, mapacho, MNA, celastrus paniculatus, yohimbe, and MEAI. The scope also extends beyond the most common categories of hallucinogens, stimulants, depressants, cannabinoids and opioids. Included, for example, are nootropics (smart drugs) and oneirogenics (lucid and vivid dream herbs). Another dimension, which is covered largely in the final section, is that of politics and the war on drugs. This is confronted head-on, with a statement of intent which is crystal clear: "People are dying because of ignorance. They are dying because unremitting propaganda is denying them essential safety information. They are dying because legislators and the media are censoring the science, and are ruthlessly pushing an ideological agenda instead. They are dying because the first casualty of war is truth, and the war on drugs is no different. This book is a step to counter this harrowing and destructive situation." Emphasised and underpinned throughout is personal safety and risk mitigation. This is the first and last message, and guides the entire narrative. This is a book that won't only fascinate and inform: it will save lives.
Author: Donald G. Barceloux
Publisher: John Wiley & Sons
ISBN: 1118106059
Category : Science
Languages : en
Pages : 1080
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Book Description
This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.
Author: Daniel M. Perrine
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 504
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Book Description
This fascinating book presents a scientifically objective, and thoroughly documented exposition of the pharmacological and psychological effects of nearly every known substance that affects human consciousness, from alcohol to Zopiclone. It also features first-hand accounts and descriptions of the social, cultural, and religious milieus in which many psychotropic plants are used, and discusses historical allusions to many literary and scientific figures who used or wrote of mind-altering drugs, including Freud, Dickens, Yeats, and Huxley. Intended for a wide audience of general readers seeking unbiased information, the book gives an accessible explanation of drug-receptor interaction and organic chemical structures, as well as descriptions of the discovery, isolation, and syntheses of the chemical substances responsible for drug activity. Written by an experienced chemist, the book nevertheless keeps technical information to a minimum.
Author:
Publisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 496
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Book Description
Author: Brian D. Earp
Publisher: Manchester University Press
ISBN: 1526145561
Category : Science
Languages : en
Pages : 327
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Book Description
What if there were a pill for love? Or an anti-love drug, designed to help us break up? This controversial and timely new book argues that recent medical advances have brought chemical control of our romantic lives well within our grasp. Substances affecting love and relationships, whether prescribed by doctors or even illicitly administered, are not some far-off speculation – indeed our most intimate connections are already being influenced by pills we take for other purposes, such as antidepressants. Treatments involving certain psychoactive substances, including MDMA—the active ingredient in Ecstasy—might soon exist to encourage feelings of love and help ordinary couples work through relationship difficulties. Others may ease a breakup or soothe feelings of rejection. Such substances could have transformative implications for how we think about and experience love. This brilliant intervention into the debate builds a case for conducting further research into "love drugs" and "anti-love drugs" and explores their ethical implications for individuals and society. Rich in anecdotal evidence and case-studies, the book offers a highly readable insight into a cutting-edge field of medical research that could have profound effects on us all. Will relationships be the same in the future? Will we still marry? It may be up to you to decide whether you want a chemical romance.
Author: Richard B. Silverman
Publisher: Elsevier
ISBN: 0080513379
Category : Science
Languages : en
Pages : 650
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Book Description
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization
Author: Markus Müller
Publisher: Springer Science & Business Media
ISBN: 3709101441
Category : Medical
Languages : en
Pages : 438
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Book Description
Today we witness an eventful time in which the powerful new forces of genomics, information technology and economics are rapidly changing the science and art of medicine. This will require more specialization than ever before. However, there is also an increasing demand for an integrated approach, which is provided by the discipline of Clinical Pharmacology (CP). CP pursues a scientific goal by studying drug action in patients and volunteers, a clinical goal by administering appropriate drug therapy and a regulatory goal by assessing the risk/benefit ratio of drug candidates in drug development and reimbursement. This introduction to current topics of CP covers traditional topics of clinical drug research and trial methodology but also provides insight in current topics like genomics, imaging technology and issues in drug reimbursement. A number of concrete case studies in clinical drug research and development help to give a better understanding of the general principles of CP.
Author: J. Moncrieff
Publisher: Springer
ISBN: 0230589448
Category : Medical
Languages : en
Pages : 288
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Book Description
This book overturns the idea that psychiatric drugs work by correcting chemical imbalance and analyzes the professional, commercial and political vested interests that have shaped this view. It provides a comprehensive critique of research on drugs including antidepressants, antipsychotics and mood stabilizers.
Author: Li Di
Publisher: Elsevier
ISBN: 0080557619
Category : Science
Languages : en
Pages : 549
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Book Description
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint
