Chemical and Molecular Basis of Nerve Activity

Chemical and Molecular Basis of Nerve Activity PDF Author: David Nachmansohn
Publisher: Elsevier
ISBN: 0323151027
Category : Medical
Languages : en
Pages : 422

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Book Description
Chemical and Molecular Basis of Nerve Activity contains 16 chapters that discuss the significant advances in the study of the molecular events underlying bioelectricity and nerve excitability. After briefly describing the physiology and mechanisms of the nervous system, this book goes on examining the physiologically significant features and nerve activity roles of acetylcholines and acetylcholinesterase. A chapter highlights the mechanism of acetylcholinerase inhibition by nerve gases and insecticides. Other chapters explore the characteristic properties of choline acetylase enzyme; the relationships between chemical forces and electrical activity; and the effect of acetylcholine and analog compounds on the isolation of receptor protein and on synaptic junctions. The remaining chapters deal with the essential role of acetylcholine in the generation of bioelectric current and the differences between axonal conduction and synaptic transmission. The supplementary texts look into the progress in the biochemistry of excitability and present an integral model of nerve excitability. This book will be of great benefit to biologists and neurologists.

Chemical and Molecular Basis of Nerve Activity

Chemical and Molecular Basis of Nerve Activity PDF Author: David Nachmansohn
Publisher: Elsevier
ISBN: 0323151027
Category : Medical
Languages : en
Pages : 422

Get Book Here

Book Description
Chemical and Molecular Basis of Nerve Activity contains 16 chapters that discuss the significant advances in the study of the molecular events underlying bioelectricity and nerve excitability. After briefly describing the physiology and mechanisms of the nervous system, this book goes on examining the physiologically significant features and nerve activity roles of acetylcholines and acetylcholinesterase. A chapter highlights the mechanism of acetylcholinerase inhibition by nerve gases and insecticides. Other chapters explore the characteristic properties of choline acetylase enzyme; the relationships between chemical forces and electrical activity; and the effect of acetylcholine and analog compounds on the isolation of receptor protein and on synaptic junctions. The remaining chapters deal with the essential role of acetylcholine in the generation of bioelectric current and the differences between axonal conduction and synaptic transmission. The supplementary texts look into the progress in the biochemistry of excitability and present an integral model of nerve excitability. This book will be of great benefit to biologists and neurologists.

Molecular Basis of Nerve Activity

Molecular Basis of Nerve Activity PDF Author: J.-P. Changeux
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110855631
Category : Science
Languages : en
Pages : 812

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Book Description
No detailed description available for "Molecular Basis of Nerve Activity".

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description


Environmental Neurotoxicology

Environmental Neurotoxicology PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045312
Category : Science
Languages : en
Pages : 167

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Book Description
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Discovering the Brain

Discovering the Brain PDF Author: National Academy of Sciences
Publisher: National Academies Press
ISBN: 0309045290
Category : Medical
Languages : en
Pages : 195

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Book Description
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Anatomy and Physiology

Anatomy and Physiology PDF Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0

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Book Description


Molecular Basis of Memory

Molecular Basis of Memory PDF Author:
Publisher: Academic Press
ISBN: 0124202004
Category : Science
Languages : en
Pages : 467

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Book Description
This special volume of Progress in Molecular Biology and Translational Science provides a current overview of how memory is processed in the brain. A broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the brain's ability to maintain information across time. Memory systems in the prefrontal cortex, hippocampus and amygdala are considered as well. In addition, the volume covers recent contributions to our understanding of memory from in vivo imaging, optogenetic, electrophysiological, biochemical and molecular biological studies. - Articles from world renowned experts in memory - Covering topics from signaling, epigenetic, RNA translation to plasticity - Methodological approaches include molecular and cellular, behavioral, electrophysiological, optogenetic and functional imaging

Botulinum Neurotoxins

Botulinum Neurotoxins PDF Author: Andreas Rummel
Publisher: Springer
ISBN: 9783642448898
Category : Medical
Languages : en
Pages : 0

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Book Description
The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.

Biology for AP ® Courses

Biology for AP ® Courses PDF Author: Julianne Zedalis
Publisher:
ISBN: 9781947172401
Category : Biology
Languages : en
Pages : 1923

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Book Description
Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Brain Architecture : Understanding the Basic Plan

Brain Architecture : Understanding the Basic Plan PDF Author: and Director NIBS Neuroscience Program University of Southern California Larry W. Swanson Milo Don and Lucille Appleman Professor of Biological Sciences
Publisher: Oxford University Press, USA
ISBN: 0198026463
Category : Medical
Languages : en
Pages : 283

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Book Description
Depending on your point of view the brain is an organ, a machine, a biological computer, or simply the most important component of the nervous system. How does it work as a whole? What are its major parts and how are they interconnected to generate thinking, feelings, and behavior? This book surveys 2,500 years of scientific thinking about these profoundly important questions from the perspective of fundamental architectural principles, and then proposes a new model for the basic plan of neural systems organization based on an explosion of structural data emerging from the neuroanatomy revolution of the 1970's. The importance of a balance between theoretical and experimental morphology is stressed throughout the book. Great advances in understanding the brain's basic plan have come especially from two traditional lines of biological thought-- evolution and embryology, because each begins with the simple and progresses to the more complex. Understanding the organization of brain circuits, which contain thousands of links or pathways, is much more difficult. It is argued here that a four-system network model can explain the structure-function organization of the brain. Possible relationships between neural networks and gene networks revealed by the human genome project are explored in the final chapter. The book is written in clear and sparkling prose, and it is profusely illustrated. It is designed to be read by anyone with an interest in the basic organization of the brain, from neuroscience to philosophy to computer science to molecular biology. It is suitable for use in neuroscience core courses because it presents basic principles of the structure of the nervous system in a systematic way.