Author: Syngress
Publisher: Elsevier
ISBN: 0080476457
Category : Computers
Languages : en
Pages : 657
Book Description
Unparalleled security management that IT professionals have been waiting for.Check Point Software Technologies is the worldwide leader in securing the Internet. The company's Secure Virtual Network (SVN) architecture provides the infrastructure that enables secure and reliable Internet communications. CheckPoint recently announced a ground-breaking user interface that meets the computer industry's Internet security requirements. The Next Generation User Interface is easy to use and offers unparalleled security management capabilities by creating a visual picture of security operations.CheckPoint Next Generation Security Administration will be a comprehensive reference to CheckPoint's newest suite of products and will contain coverage of: Next Generation User Interface, Next Generation Management, Next Generation Performance, Next Generation VPN Clients, and Next Generation Systems. CheckPoint are a company to watch, they have captured over 50% of the VPN market and over 40% of the firewall market according to IDC ResearchOver 29,000 IT professionals are CheckPont Certified This is the first book to covers all components of CheckPoint's new suite of market-leading security products - it will be in demand!
Checkpoint Next Generation Security Administration
Author: Syngress
Publisher: Elsevier
ISBN: 0080476457
Category : Computers
Languages : en
Pages : 657
Book Description
Unparalleled security management that IT professionals have been waiting for.Check Point Software Technologies is the worldwide leader in securing the Internet. The company's Secure Virtual Network (SVN) architecture provides the infrastructure that enables secure and reliable Internet communications. CheckPoint recently announced a ground-breaking user interface that meets the computer industry's Internet security requirements. The Next Generation User Interface is easy to use and offers unparalleled security management capabilities by creating a visual picture of security operations.CheckPoint Next Generation Security Administration will be a comprehensive reference to CheckPoint's newest suite of products and will contain coverage of: Next Generation User Interface, Next Generation Management, Next Generation Performance, Next Generation VPN Clients, and Next Generation Systems. CheckPoint are a company to watch, they have captured over 50% of the VPN market and over 40% of the firewall market according to IDC ResearchOver 29,000 IT professionals are CheckPont Certified This is the first book to covers all components of CheckPoint's new suite of market-leading security products - it will be in demand!
Publisher: Elsevier
ISBN: 0080476457
Category : Computers
Languages : en
Pages : 657
Book Description
Unparalleled security management that IT professionals have been waiting for.Check Point Software Technologies is the worldwide leader in securing the Internet. The company's Secure Virtual Network (SVN) architecture provides the infrastructure that enables secure and reliable Internet communications. CheckPoint recently announced a ground-breaking user interface that meets the computer industry's Internet security requirements. The Next Generation User Interface is easy to use and offers unparalleled security management capabilities by creating a visual picture of security operations.CheckPoint Next Generation Security Administration will be a comprehensive reference to CheckPoint's newest suite of products and will contain coverage of: Next Generation User Interface, Next Generation Management, Next Generation Performance, Next Generation VPN Clients, and Next Generation Systems. CheckPoint are a company to watch, they have captured over 50% of the VPN market and over 40% of the firewall market according to IDC ResearchOver 29,000 IT professionals are CheckPont Certified This is the first book to covers all components of CheckPoint's new suite of market-leading security products - it will be in demand!
RIA Federal Tax Handbook
Author:
Publisher:
ISBN:
Category : Income tax
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category : Income tax
Languages : en
Pages : 0
Book Description
Checkpoint Watch
Author: Yehudit Kirstein Keshet
Publisher: Zed Books
ISBN: 9781842777190
Category : History
Languages : en
Pages : 212
Book Description
This book is a critical exploration of Israel's curfew-closure policy in the Occupied Palestinian Territories through the eyes of CheckpointWatch, an organization of Israeli women monitoring human rights abuses. The book combines observers' daily reports from the checkpoints and along the Separation Wall, with analysis of the bureaucracy that supports the ongoing occupation. Keshet demonstrates the link between Israeli bureaucracy and the closure system as integral to a wider project of ethnic cleansing. As co-founder of the group, Keshet critically reviews the organisation's transformation from a feminist, radical protest movement to one both reclaimed by, and reclaiming, the consensus. Illustrating the nature of Israeli mainstream discourse as both anodyne and cruel, the book also analyses Israeli media representation of Checkpoint Watch and human rights activism in general. Keshet contends that the dilemmas of these Israeli women, torn between opposition to the Occupation and their loyalty to the state, reflects political divisions within Israel society as a whole.
Publisher: Zed Books
ISBN: 9781842777190
Category : History
Languages : en
Pages : 212
Book Description
This book is a critical exploration of Israel's curfew-closure policy in the Occupied Palestinian Territories through the eyes of CheckpointWatch, an organization of Israeli women monitoring human rights abuses. The book combines observers' daily reports from the checkpoints and along the Separation Wall, with analysis of the bureaucracy that supports the ongoing occupation. Keshet demonstrates the link between Israeli bureaucracy and the closure system as integral to a wider project of ethnic cleansing. As co-founder of the group, Keshet critically reviews the organisation's transformation from a feminist, radical protest movement to one both reclaimed by, and reclaiming, the consensus. Illustrating the nature of Israeli mainstream discourse as both anodyne and cruel, the book also analyses Israeli media representation of Checkpoint Watch and human rights activism in general. Keshet contends that the dilemmas of these Israeli women, torn between opposition to the Occupation and their loyalty to the state, reflects political divisions within Israel society as a whole.
Checkpoint
Author: David Albahari
Publisher: Restless Books
ISBN: 1632061937
Category : Fiction
Languages : en
Pages : 149
Book Description
From the award-winning Serbian author David Albahari comes a devastating and Kafkaesque war fable about an army unit sent to guard a military checkpoint with no idea where they are or who the enemy might be. Atop a hill, deep in the forest, an army unit is dropped off to guard a checkpoint. The commander doesn’t know where they are, what border they’re protecting, or why. Their map is useless. The radio crackles with a language no one can recognize. A soldier is found dead in a latrine and the unit vows vengeance—but the killer, like the enemy, is unknown. Amid orgies and massacres, the commander struggles to maintain order and keep his soldiers alive, but he can’t be sure whether they’re fighting a war or caught in some bizarre military experiment. Equal parts Waiting for Godot and Catch-22, David Albahari’s Checkpoint is a haunting and hysterical confrontation with the absurdity of war. Praise for Checkpoint: "A satirical take on war in the vein of Catch-22 and Slaughterhouse Five, Serbian author David Albahari’s Checkpointis shocking and comic in equal turns, skillfully pulled together by the force of Albahari’s wit.... Visceral, wild, and often hilarious, Checkpoint is a dark delight." —Ho Lin, Foreword Reviews, Starred Review “A worthy descendant of The Good Soldier Svejk and Catch-22.” —Kirkus Reviews “Checkpoint is a tornado of a book. David Albahari, a noted Serbian author who lives in Canada, muscles this Kafkaesque short novel into the war-is-absurd literary tradition in one tremendous 183-page paragraph…. Stylistically, JP Donleavy and Gary Shteyngart come to mind at times, while imagistically one might think of Goya, Picasso, or the Surrealists. But Albahari has a distinctive voice, and it comes through vividly in Ellen Elias-Bursać’s able translation from the Serbian.” —Jon Sobel, Blogcritics “Between adventure and apocalypse... Kafka and Kubrick...combining in grotesque-comical manner all the ridiculousness, beauty, horror, subtlety and extravagance that literature can hold.“ —Neue Zürcher Zeitung
Publisher: Restless Books
ISBN: 1632061937
Category : Fiction
Languages : en
Pages : 149
Book Description
From the award-winning Serbian author David Albahari comes a devastating and Kafkaesque war fable about an army unit sent to guard a military checkpoint with no idea where they are or who the enemy might be. Atop a hill, deep in the forest, an army unit is dropped off to guard a checkpoint. The commander doesn’t know where they are, what border they’re protecting, or why. Their map is useless. The radio crackles with a language no one can recognize. A soldier is found dead in a latrine and the unit vows vengeance—but the killer, like the enemy, is unknown. Amid orgies and massacres, the commander struggles to maintain order and keep his soldiers alive, but he can’t be sure whether they’re fighting a war or caught in some bizarre military experiment. Equal parts Waiting for Godot and Catch-22, David Albahari’s Checkpoint is a haunting and hysterical confrontation with the absurdity of war. Praise for Checkpoint: "A satirical take on war in the vein of Catch-22 and Slaughterhouse Five, Serbian author David Albahari’s Checkpointis shocking and comic in equal turns, skillfully pulled together by the force of Albahari’s wit.... Visceral, wild, and often hilarious, Checkpoint is a dark delight." —Ho Lin, Foreword Reviews, Starred Review “A worthy descendant of The Good Soldier Svejk and Catch-22.” —Kirkus Reviews “Checkpoint is a tornado of a book. David Albahari, a noted Serbian author who lives in Canada, muscles this Kafkaesque short novel into the war-is-absurd literary tradition in one tremendous 183-page paragraph…. Stylistically, JP Donleavy and Gary Shteyngart come to mind at times, while imagistically one might think of Goya, Picasso, or the Surrealists. But Albahari has a distinctive voice, and it comes through vividly in Ellen Elias-Bursać’s able translation from the Serbian.” —Jon Sobel, Blogcritics “Between adventure and apocalypse... Kafka and Kubrick...combining in grotesque-comical manner all the ridiculousness, beauty, horror, subtlety and extravagance that literature can hold.“ —Neue Zürcher Zeitung
Cambridge Checkpoint Lower Secondary World English Student's Book 7
Author: Fiona Macgregor
Publisher: Hodder Education
ISBN: 1398307548
Category : Education
Languages : en
Pages : 364
Book Description
Checkpoint World English Stage 7 has been endorsed by Cambridge Assessment International Education. This series offers full coverage of the learning objectives for the Cambridge Lower Secondary English as a Second language curriculum framework (0876) and is mapped to the Common European Framework of Reference. - Stimulate learners with model texts and a range of activities to develop skills, knowledge and comprehension. - Revisit previous knowledge with the 'Do you remember?' feature to recap topics and activate schema, along with practice tasks, exercises and 'Challenge yourself' activities to consolidate learning. - Clearly address the key objectives: reading, writing, speaking, listening and use of English. - Support activities and knowledge covered in the Student's Book with the accompanying Workbook and Teacher's Guide with Boost subscription. - Audio files are available free at https://www.hoddereducation.co.uk/cambridgeextras
Publisher: Hodder Education
ISBN: 1398307548
Category : Education
Languages : en
Pages : 364
Book Description
Checkpoint World English Stage 7 has been endorsed by Cambridge Assessment International Education. This series offers full coverage of the learning objectives for the Cambridge Lower Secondary English as a Second language curriculum framework (0876) and is mapped to the Common European Framework of Reference. - Stimulate learners with model texts and a range of activities to develop skills, knowledge and comprehension. - Revisit previous knowledge with the 'Do you remember?' feature to recap topics and activate schema, along with practice tasks, exercises and 'Challenge yourself' activities to consolidate learning. - Clearly address the key objectives: reading, writing, speaking, listening and use of English. - Support activities and knowledge covered in the Student's Book with the accompanying Workbook and Teacher's Guide with Boost subscription. - Audio files are available free at https://www.hoddereducation.co.uk/cambridgeextras
Checkpoint Controls and Cancer
Author: Axel H. Schönthal
Publisher: Springer Science & Business Media
ISBN: 1592597882
Category : Medical
Languages : en
Pages : 328
Book Description
Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the damage cannot be repaired. Moreover, internal errors can occur during the highly orchestrated replication of the cellular genome and its distribution into daughter cells. Here, the temporal order of these cell cycle events must be strictly enforced—for example, to ensure that DNA replication is c- plete and occurs only once before cell division, or to monitor mitotic spindle assembly, and to prevent exit from mitosis until chromosome segregation has been completed. Thus, well functioning checkpoint mechanisms are central to the maintenance of genomic integrity and the basic viability of cells and, the- fore, are essential for proper development and survival. The importance of proper functioning of checkpoints becomes plainly obvious under conditions in which this control network malfunctions and fails. Depending on the severity and timing, failure of this machinery can lead to embryonic lethality, genetic diseases, and cancer.
Publisher: Springer Science & Business Media
ISBN: 1592597882
Category : Medical
Languages : en
Pages : 328
Book Description
Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the damage cannot be repaired. Moreover, internal errors can occur during the highly orchestrated replication of the cellular genome and its distribution into daughter cells. Here, the temporal order of these cell cycle events must be strictly enforced—for example, to ensure that DNA replication is c- plete and occurs only once before cell division, or to monitor mitotic spindle assembly, and to prevent exit from mitosis until chromosome segregation has been completed. Thus, well functioning checkpoint mechanisms are central to the maintenance of genomic integrity and the basic viability of cells and, the- fore, are essential for proper development and survival. The importance of proper functioning of checkpoints becomes plainly obvious under conditions in which this control network malfunctions and fails. Depending on the severity and timing, failure of this machinery can lead to embryonic lethality, genetic diseases, and cancer.
Checkpoint Charlie
Author: Iain MacGregor
Publisher: Scribner
ISBN: 1982100044
Category : History
Languages : en
Pages : 352
Book Description
A “constantly captivating…well-researched and often moving” (The Wall Street Journal) history of Checkpoint Charlie, the famous military gate on the border of East and West Berlin where the United States confronted the USSR during the Cold War. In the early 1960s, East Germany committed a billion dollars to the creation of the Berlin Wall, an eleven-foot-high barrier that consisted of seventy-nine miles of fencing, 300 watchtowers, 250 guard dog runs, twenty bunkers, and was operated around the clock by guards who shot to kill. Over the next twenty-eight years, at least five thousand people attempt to smash through it, swim across it, tunnel under it, or fly over it. In 1989, the East German leadership buckled in the face of a civil revolt that culminated in half a million East Berliners demanding an end to the ban on free movement. The world’s media flocked to capture the moment which, perhaps more than any other, signaled the end of the Cold War. Checkpoint Charlie had been the epicenter of global conflict for nearly three decades. Now, “in capturing the essence of the old Cold War [MacGregor] may just have helped us to understand a bit more about the new one” (The Times, London)—the mistrust, oppression, paranoia, and fear that gripped the world throughout this period. Checkpoint Charlie is about the nerve-wracking confrontation between the West and USSR, highlighting such important global figures as Eisenhower, Stalin, JFK, Nikita Khrushchev, Mao Zedung, Nixon, Reagan, and other politicians of the period. He also includes never-before-heard interviews with the men who built and dismantled the Wall; children who crossed it; relatives and friends who lost loved ones trying to escape over it; military policemen and soldiers who guarded the checkpoints; CIA, MI6, and Stasi operatives who oversaw operations across its borders; politicians whose ambitions shaped it; journalists who recorded its story; and many more whose living memories contributed to the full story of Checkpoint Charlie.
Publisher: Scribner
ISBN: 1982100044
Category : History
Languages : en
Pages : 352
Book Description
A “constantly captivating…well-researched and often moving” (The Wall Street Journal) history of Checkpoint Charlie, the famous military gate on the border of East and West Berlin where the United States confronted the USSR during the Cold War. In the early 1960s, East Germany committed a billion dollars to the creation of the Berlin Wall, an eleven-foot-high barrier that consisted of seventy-nine miles of fencing, 300 watchtowers, 250 guard dog runs, twenty bunkers, and was operated around the clock by guards who shot to kill. Over the next twenty-eight years, at least five thousand people attempt to smash through it, swim across it, tunnel under it, or fly over it. In 1989, the East German leadership buckled in the face of a civil revolt that culminated in half a million East Berliners demanding an end to the ban on free movement. The world’s media flocked to capture the moment which, perhaps more than any other, signaled the end of the Cold War. Checkpoint Charlie had been the epicenter of global conflict for nearly three decades. Now, “in capturing the essence of the old Cold War [MacGregor] may just have helped us to understand a bit more about the new one” (The Times, London)—the mistrust, oppression, paranoia, and fear that gripped the world throughout this period. Checkpoint Charlie is about the nerve-wracking confrontation between the West and USSR, highlighting such important global figures as Eisenhower, Stalin, JFK, Nikita Khrushchev, Mao Zedung, Nixon, Reagan, and other politicians of the period. He also includes never-before-heard interviews with the men who built and dismantled the Wall; children who crossed it; relatives and friends who lost loved ones trying to escape over it; military policemen and soldiers who guarded the checkpoints; CIA, MI6, and Stasi operatives who oversaw operations across its borders; politicians whose ambitions shaped it; journalists who recorded its story; and many more whose living memories contributed to the full story of Checkpoint Charlie.
Checkpoints
Author: Brian Mills
Publisher: Tyndale House
ISBN: 1612913768
Category : Young Adult Nonfiction
Languages : en
Pages : 167
Book Description
Society today rejects the idea of absolute truth and is openly hostile toward God. For boys who want to be more like Christ, going through adolescence in this culture is like crossing a minefield without a map. They need parents and youth workers to engage with them early and equip them with the skills needed to thrive. Checkpoints plots a course through this enemy territory that not only steers young men toward godliness but also explains how to avoid potential pitfalls. Checkpoints honestly talks about the core issues boys face, opening a vital dialogue between fathers and sons, pastors and students. Key takeaways: Created by student pastors with 20+ years in ministry 8 lessons Written in a devotional style Guys spend just 15 minutes each day to prepare them for their small group time.
Publisher: Tyndale House
ISBN: 1612913768
Category : Young Adult Nonfiction
Languages : en
Pages : 167
Book Description
Society today rejects the idea of absolute truth and is openly hostile toward God. For boys who want to be more like Christ, going through adolescence in this culture is like crossing a minefield without a map. They need parents and youth workers to engage with them early and equip them with the skills needed to thrive. Checkpoints plots a course through this enemy territory that not only steers young men toward godliness but also explains how to avoid potential pitfalls. Checkpoints honestly talks about the core issues boys face, opening a vital dialogue between fathers and sons, pastors and students. Key takeaways: Created by student pastors with 20+ years in ministry 8 lessons Written in a devotional style Guys spend just 15 minutes each day to prepare them for their small group time.
Checkpoint Controls and Targets in Cancer Therapy
Author: Zahid H. Siddik
Publisher: Springer Science & Business Media
ISBN: 1607611783
Category : Medical
Languages : en
Pages : 276
Book Description
Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular proliferation, is an inherent characteristic of cancer. This loss may occur through aberration in any single component involved in signal transduction pathways that orchestrate checkpoint regulation, which may manifest through either a failure to activate the checkpoint or a failure to respond to the activated checkpoint. In normal cells, checkpoint pathways are activated when genetic or cellular homeostasis is compromised, and signals are then transduced to re-stabilize homeostasis, and, failing this, to activate the apoptotic machinery to induce a cellular suicidal response. This implies that both survival and cell death pathways are induced following checkpoint activation, and that the final decision is dependant on the net result of integrating the two sets of signals. It is intriguing that checkpoint pathways are also critical in cancer therapy to provide an apoptotic stimulus when cellular damage induced by the therapeutic agent is detected by the sensor system. Therefore, it is not surprising that failure in pro-survival checkpoint response will render tumor cells hypersensitive to cytotoxics and, conversely, failure in pro-apoptotic checkpoint response will induce genetic instability and/or therapeutic resistance. Understanding the intricacies of checkpoint response is, therefore, central to the design of therapeutic regimen that will enhance antitumor effects. Although early versions of this design entail combination of cytotoxic agents with cell cycle or checkpoint inhibitors, a greater understanding of the concepts could make such combinations clinically more effective. The contributions in this book will consolidate the current state of knowledge on checkpoint responses that may lay the foundation for hypothesis-driven rational approaches in advancing the management of cancer. The immediate attraction of the book to the scientific community is that it represents a timely opportunity to build upon existing concepts of checkpoints to expand our understanding of the inner workings of the critical checkpoint machinery. The present understanding has provided ample appreciation that response to checkpoint activation is manifested through coordinated inhibition of cyclin-dependent kinase (CDK) complexes in G1, S and/or the G2 phase in order to arrest the cell cycle. Kinase inhibition can occur through several mechanisms, including inhibitory phosphorylation of CDK, destruction of the cognate cyclins, and recruitment of CDK inhibitors from the INK and WAF1/CIP1 families. However, the wealth of information from recent discoveries needs to be examined critically to consolidate our conceptual knowledge of checkpoints. At the same time, there is acute awareness in the diversity of checkpoint response between cytotoxic agents, and this serves as a reminder of the magnitude of complexity that is inherent in checkpoint regulation. This volume is intended to bring the cancer research community closer toward an improved understanding of this regulation, how checkpoint abnormalities can impact negatively on cancer therapy, and emerging strategies to target checkpoint response as a therapeutic end-point.
Publisher: Springer Science & Business Media
ISBN: 1607611783
Category : Medical
Languages : en
Pages : 276
Book Description
Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular proliferation, is an inherent characteristic of cancer. This loss may occur through aberration in any single component involved in signal transduction pathways that orchestrate checkpoint regulation, which may manifest through either a failure to activate the checkpoint or a failure to respond to the activated checkpoint. In normal cells, checkpoint pathways are activated when genetic or cellular homeostasis is compromised, and signals are then transduced to re-stabilize homeostasis, and, failing this, to activate the apoptotic machinery to induce a cellular suicidal response. This implies that both survival and cell death pathways are induced following checkpoint activation, and that the final decision is dependant on the net result of integrating the two sets of signals. It is intriguing that checkpoint pathways are also critical in cancer therapy to provide an apoptotic stimulus when cellular damage induced by the therapeutic agent is detected by the sensor system. Therefore, it is not surprising that failure in pro-survival checkpoint response will render tumor cells hypersensitive to cytotoxics and, conversely, failure in pro-apoptotic checkpoint response will induce genetic instability and/or therapeutic resistance. Understanding the intricacies of checkpoint response is, therefore, central to the design of therapeutic regimen that will enhance antitumor effects. Although early versions of this design entail combination of cytotoxic agents with cell cycle or checkpoint inhibitors, a greater understanding of the concepts could make such combinations clinically more effective. The contributions in this book will consolidate the current state of knowledge on checkpoint responses that may lay the foundation for hypothesis-driven rational approaches in advancing the management of cancer. The immediate attraction of the book to the scientific community is that it represents a timely opportunity to build upon existing concepts of checkpoints to expand our understanding of the inner workings of the critical checkpoint machinery. The present understanding has provided ample appreciation that response to checkpoint activation is manifested through coordinated inhibition of cyclin-dependent kinase (CDK) complexes in G1, S and/or the G2 phase in order to arrest the cell cycle. Kinase inhibition can occur through several mechanisms, including inhibitory phosphorylation of CDK, destruction of the cognate cyclins, and recruitment of CDK inhibitors from the INK and WAF1/CIP1 families. However, the wealth of information from recent discoveries needs to be examined critically to consolidate our conceptual knowledge of checkpoints. At the same time, there is acute awareness in the diversity of checkpoint response between cytotoxic agents, and this serves as a reminder of the magnitude of complexity that is inherent in checkpoint regulation. This volume is intended to bring the cancer research community closer toward an improved understanding of this regulation, how checkpoint abnormalities can impact negatively on cancer therapy, and emerging strategies to target checkpoint response as a therapeutic end-point.
Multidisciplinary Management of Cancer Patients with Immune-Related Adverse Events from Checkpoint Inhibitors
Author: Mar Riveiro Barciela
Publisher: Frontiers Media SA
ISBN: 2832513689
Category : Medical
Languages : en
Pages : 93
Book Description
Publisher: Frontiers Media SA
ISBN: 2832513689
Category : Medical
Languages : en
Pages : 93
Book Description