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Author: Stephen G. Waxman
Publisher: MIT Press
ISBN: 0262344734
Category : Medical
Languages : en
Pages : 320
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Book Description
A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire. Two soldiers, both with wounds injuring the same nerve, show very different responses: one is disabled by neuropathic pain, unable to touch the injured limb because even the lightest contact triggers excruciating discomfort; the other notices numbness but no pain at all. Could the difference lie in their genes? In this book, described in the foreword by Nobel Laureate James Rothman as “so well written that it reads like a detective novel,” Stephen Waxman recounts the search for a gene that controls pain—a search spanning more than thirty years and three continents. The story moves from genes to pain-signaling neurons that scream when they should be silent to people with a rare genetic disorder who feel they are on fire. Waxman explains that if pain-signaling neurons are injured by trauma or disease, they can become hyperactive and send pain signals to the brain even without external stimulus. Studying the hyperactive mutant pain gene in man on fire syndrome has pointed the way to molecules that produce pain more broadly within the general population, in the rest of us. Waxman's account of the many steps that led to discovery of the pain gene tells the story behind the science, of how science happens.
Author: Stephen G. Waxman
Publisher: MIT Press
ISBN: 0262344734
Category : Medical
Languages : en
Pages : 320
Get Book Here
Book Description
A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire. Two soldiers, both with wounds injuring the same nerve, show very different responses: one is disabled by neuropathic pain, unable to touch the injured limb because even the lightest contact triggers excruciating discomfort; the other notices numbness but no pain at all. Could the difference lie in their genes? In this book, described in the foreword by Nobel Laureate James Rothman as “so well written that it reads like a detective novel,” Stephen Waxman recounts the search for a gene that controls pain—a search spanning more than thirty years and three continents. The story moves from genes to pain-signaling neurons that scream when they should be silent to people with a rare genetic disorder who feel they are on fire. Waxman explains that if pain-signaling neurons are injured by trauma or disease, they can become hyperactive and send pain signals to the brain even without external stimulus. Studying the hyperactive mutant pain gene in man on fire syndrome has pointed the way to molecules that produce pain more broadly within the general population, in the rest of us. Waxman's account of the many steps that led to discovery of the pain gene tells the story behind the science, of how science happens.
Author: Nora Roberts
Publisher: Penguin
ISBN: 1101513780
Category : Fiction
Languages : en
Pages : 344
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Book Description
In this #1 New York Times bestseller, Nora Roberts delves into the world of elite firefighters who thrive on danger and adrenaline—men and women who wouldn’t know how to live life if it wasn’t on the edge. Little else in life is as dangerous as fire jumping. But there’s also little else as thrilling—at least to Rowan Tripp. Being a Missoula smoke jumper is in Rowan’s blood: her father is a legend in the field. At this point, returning to the wilds of Montana for the season feels like coming home—even with reminders of the partner she lost last season still lingering in the air. One of the best of this year’s rookie crop, Gulliver Curry is a walking contradiction, a hotshot firefighter with a big vocabulary and a winter job at a kids’ arcade. And though Rowan, as a rule, doesn’t hook up with other smoke jumpers, Gull is convinced he can change her mind... But everything is thrown off balance when a dark presence lashes out against Rowan, looking to blame someone for last year’s tragedy. Rowan knows she can’t complicate things with Gull—any distractions in the air or on the ground could be lethal. But if she doesn’t find someone she can lean on when the heat gets intense, her life may go down in flames.
Author: Norman MacLean
Publisher: University of Chicago Press
ISBN: 022645049X
Category : History
Languages : en
Pages : 370
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Book Description
National Book Critics Circle Award Winner: “The terrifying story of the worst disaster in the history of the US Forest Service’s elite Smokejumpers.” —Kirkus Reviews A devastating and lyrical work of nonfiction, Young Men and Fire describes the events of August 5, 1949, when a crew of fifteen of the US Forest Service’s elite airborne firefighters, the Smokejumpers, stepped into the sky above a remote forest fire in the Montana wilderness. Two hours after their jump, all but three of the men were dead or mortally burned. Haunted by these deaths for forty years, Norman Maclean puts together the scattered pieces of the Mann Gulch tragedy in this extraordinary book. Alongside Maclean’s now-canonical A River Runs Through It and Other Stories, Young Men and Fire is recognized today as a classic of the American West. This edition of Maclean’s later triumph—the last book he would write—includes a powerful new foreword by Timothy Egan, author of The Big Burn and The Worst Hard Time. As moving and profound as when it was first published, Young Men and Fire honors the literary legacy of a man who gave voice to an essential corner of the American soul. “A moving account of humanity, nature, and the perseverance of the human spirit.” —Library Journal “Haunting.” —The Wall Street Journal “Engrossing.” —Publishers Weekly
Author: Bruce Bryans
Publisher: Createspace Independent Publishing Platform
ISBN: 9781514128381
Category : Couples
Languages : en
Pages : 0
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Book Description
Discover How to Get the Guy You Want and Avoid Dead-End Relationships If a man doesn''t take you seriously he may feel compelled to have a good time with you. Unfortunately, this good time will last until you finally realize you''re being taken for a ride or until Mr. Time-Waster moves on to the woman he REALLY wants. In cases like this, what a woman really requires are two things: a healthy amount of self-respect and a set of "player-proof" dating rules that will allow her to make wise dating decisions as she navigates the treacherous territory of finding Mr. Right. How to Keep a Man Interested Without Playing Games or Becoming His Doormat Many dating advice books for women tout the idea that a high level of confidence is key when dealing with men. However, while this is partially true, being confident, at least in regards to making a man pursue you, is pointless without understanding how to apply that confidence in various dating situations when dealing with men. A woman''s confidence is communicated to a man by what she stands for and what she doesn''t. Being able to confidently socialize with men, having confident body language, and illustrating confidence in your femininity will only go so far if you still allow men to have their way with your emotions, time, affections, body, and anything else for that matter. Self-confidence makes a woman more attractive, but unless it effects how she enforces her personal boundaries it won''t do anything to keep a man interested in her for the long-term. How to Date a Man to Keep Him Calling and Falling For You Women with strong personal boundaries are principle-centered, not men-centered or romance-centered. To them, their personal values, such as giving and receiving unconditional love, are more important to them than needing to be with any one particular guy. When a woman has strong personal boundaries she doesn''t make excuses because of a man''s handsomeness, status, wealth, race, background, promises, sexual chemistry, etc. She sticks to her guns and refuses to settle for dating situations that might cause her distress or jeopardize her future happiness. This book was designed to show women how men appraise female behavior in order to determine a woman''s level of self-respect and therefore, her value as a romantic partner. In it, you''ll discover the timeless seduction secrets and dating rules for women that will help you avoid those dating mistakes that make could make a woman appear desperate, needy, commonplace, or even "unqualified" for a serious commitment to a great guy. Here''s what you''re going to learn inside: The most powerful form of male seduction that can KEEP a woman helplessly "addicted" to chasing a man. How to keep a man interested by doing the one thing MOST women are terrified of doing when they find a great guy. An irritating habit that causes high-quality men to stop pursuing a woman almost INSTANTLY. How to "rebuff" undesirable male behavior and get the guy you want to either take you seriously or take a HIKE! A simple "Ego-Popping" phrase that burns into a man''s memory, keeps you STUCK on his mind, and makes him DESPERATE to see you again. How to seduce a man and MELT his heart by overwhelming him with the ONE THING only the RIGHT woman can give him. A dangerous and common dating mistake that FORCES a man to disappear or "log out" of a relationship...for GOOD. Foolproof dating rules for women (the "Nice Girls") who feel that men CONSTANTLY take advantage of their love and kindness. And much, much more... Would You Like to Know More? Get started right away and discover how to get the guy and keep him interested in you without playing games. Scroll to the top of the page and select the ''buy button'' now.
Author: Ann Marie Walker
Publisher: Penguin
ISBN: 0698194772
Category : Fiction
Languages : en
Pages : 254
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Book Description
The second in the “seriously sexy and sinfully steamy”* Chasing Fire series, about a pain too deep to forgive and a passion too hot to forget... Alessandra Sinclair knows that Hudson Chase is the last man she should want. The boy from the wrong side of the tracks has grown into a man who would do anything to get ahead, even if it means breaking Allie’s heart. But whenever she’s near him, the attraction between them is undeniable. And now that they’re working together, keeping her distance from Hudson is almost as impossible as keeping her feelings in check... Hudson already lost Allie once and he refuses to lose her again. He’s determined to use their new business partnership to rekindle the spark he knows is still there. Only the closer he gets to winning her over, the clearer it becomes there are still secrets that could tear them apart for good... Praise for Remind Me “An exceptional debut...Can’t wait for more from this writing duo!”—*Tara Sue Me, New York Times Bestselling Author of The Submissive
Author: Ray Bradbury
Publisher: Simon and Schuster
ISBN: 0743247221
Category : Fiction
Languages : en
Pages : 217
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Book Description
Set in the future when "firemen" burn books forbidden by the totalitarian "brave new world" regime.
Author: Avery Kingston
Publisher: Fire and Fury
ISBN: 9781980794592
Category : Fiction
Languages : en
Pages : 370
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Book Description
A military alpha hero. A flirtatious vixen. A crazed game of seduction. One pair of panties changed his life. "I'm putting my panties in your back pocket. You have until two am to get them back to me. If you do, you will be rewarded. Handsomely." Those were the words Victoria Johnson whispered to Scott Harris after she stuffed a pair of lacy red panties into his back pocket. That was Tori's favorite game: No strings attached sex. But he'd have to chase her first. Years later, when Scott returns from Afghanistan minus one leg, he thinks the sexual games are over. His military career is over. Hell, his life is over. But then Tori shows up in his hospital room as fiery and flirtatious as the day he left. It turns out she's more than just a beautiful disaster with sexy red panties. Much more. She may be trouble but she's everything he's ever wanted. Except for Tori, things are never that simple. Because Tori faces a tragedy of her own. An accident that rips her life apart, leaving her without sight and struggling to recover the woman she once was. For Scott, Tori's still the one he's waited his whole life for. He's done letting fate tear them apart. It will be a challenge to win her shattered heart once and for all. Lucky thing Scott Harris never backs away from a challenge. Chasing Fire is a full length romance with LOTS of steam and a HEA. Featuring a hot-as-hell alpha and a sexy artist who both have filthy mouths. Intended for a mature audience.
Author: James Bennett
Publisher: Orbit
ISBN: 0316390712
Category : Fiction
Languages : en
Pages : 430
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Book Description
"A thrilling fusion of myth and modernity," revel in this explosive debut fantasy of magic and mayhem that"will have you rooting for dragons over humans and loving every minute of it."(Kevin Hearne, New York Times bestselling author) There's nothing special about Ben Garston. . .or so he'd have you believe. He won't tell you, for instance, that he's also known as Red Ben. That the world of myth and legend isn't just a fantasy, as we've been led to believe. And he certainly can't let you know the secret of what's hiding just beneath his skin. . . But now a centuries-old rivalry has just resurfaced, and the delicate balance between his world and ours is about to be shattered. Something is hiding in the heart of the city -- and it's about to be unleashed. Behind every myth, there's a spark of truth. . .
Author: Cassie Sanchez
Publisher: Morgan James Publishing
ISBN: 1631956108
Category : Fiction
Languages : en
Pages : 319
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Book Description
Chasing the Darkness is a story about vengeance and redemption and takes place in a land called Pandaren where there are two types of people - those with magic, Spectrals, and those without. Azrael, obsessed with revenge and power, undergoes a procedure giving him magic, but an unexpected side effect causes him to feel emotions he’s blocked for years. As an assassin and second in command of the Watch Guard, he has become a liability. Azrael is betrayed by his team and rescued by the people he’s hunted. He learns his beliefs and purpose are based on lies and has to choose the path of vengeance or the road to redemption. Chasing the Darkness entertains readers who enjoy character-driven stories with twists and turns. Chasing the Darkness is a fast-paced novel with magic, sword fights, and romance that keeps readers turning the page. The underlying themes, besides redemption, include forgiveness, sacrifice, and learning that one’s worth is not defined by one’s past.
Author: Timothy Egan
Publisher: HarperCollins
ISBN: 0547416865
Category : History
Languages : en
Pages : 349
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Book Description
National Book Award–winner Timothy Egan turns his historian's eye to the largest-ever forest fire in America and offers an epic, cautionary tale for our time. On the afternoon of August 20, 1910, a battering ram of wind moved through the drought-stricken national forests of Washington, Idaho, and Montana, whipping the hundreds of small blazes burning across the forest floor into a roaring inferno that jumped from treetop to ridge as it raged, destroying towns and timber in the blink of an eye. Forest rangers had assembled nearly ten thousand men to fight the fires, but no living person had seen anything like those flames, and neither the rangers nor anyone else knew how to subdue them. Egan recreates the struggles of the overmatched rangers against the implacable fire with unstoppable dramatic force, and the larger story of outsized president Teddy Roosevelt and his chief forester, Gifford Pinchot, that follows is equally resonant. Pioneering the notion of conservation, Roosevelt and Pinchot did nothing less than create the idea of public land as our national treasure, owned by every citizen. Even as TR's national forests were smoldering they were saved: The heroism shown by his rangers turned public opinion permanently in favor of the forests, though it changed the mission of the forest service in ways we can still witness today. This e-book includes a sample chapter of SHORT NIGHTS OF THE SHADOW CATCHER.
