Characterizing Intermediates that Govern Reactivity in Mononuclear Nonheme Iron Enzymes

Characterizing Intermediates that Govern Reactivity in Mononuclear Nonheme Iron Enzymes PDF Author: Shyam Rajan Iyer
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Characterizing Intermediates that Govern Reactivity in Mononuclear Nonheme Iron Enzymes

Characterizing Intermediates that Govern Reactivity in Mononuclear Nonheme Iron Enzymes PDF Author: Shyam Rajan Iyer
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Inorganic High Pressure Chemistry

Inorganic High Pressure Chemistry PDF Author: Rudi van Eldik
Publisher: Elsevier Publishing Company
ISBN:
Category : Science
Languages : en
Pages : 468

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Natural Product Biosynthesis

Natural Product Biosynthesis PDF Author: Christopher T. Walsh
Publisher: Royal Society of Chemistry
ISBN: 1788010760
Category : Science
Languages : en
Pages : 787

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Book Description
This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

2-Oxoglutarate-Dependent Oxygenases

2-Oxoglutarate-Dependent Oxygenases PDF Author: Christopher J Schofield
Publisher: Royal Society of Chemistry
ISBN: 1849739501
Category : Science
Languages : en
Pages : 508

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Book Description
Since the discovery of the first examples of 2-oxoglutarate-dependent oxygenase-catalysed reactions in the 1960s, a remarkably broad diversity of alternate reactions and substrates has been revealed, and extensive advances have been achieved in our understanding of the structures and catalytic mechanisms. These enzymes are important agrochemical targets and are being pursued as therapeutic targets for a wide range of diseases including cancer and anemia. This book provides a central source of information that summarizes the key features of the essential group of 2-oxoglutarate-dependent dioxygenases and related enzymes. Given the numerous recent advances and biomedical interest in the field, this book aims to unite the latest research for those already working in the field as well as to provide an introduction for those newly approaching the topic, and for those interested in translating the basic science into medicinal and agricultural benefits. The book begins with four broad chapters that highlight critical aspects, including an overview of possible catalytic reactions, structures and mechanisms. The following seventeen chapters focus on carefully selected topics, each written by leading experts in the area. Readers will find explanations of rapidly evolving research, from the chemistry of isopenicillin N synthase to the oxidation mechanism of 5-methylcytosine in DNA by ten-eleven-translocase oxygenases.

Heme Peroxidases

Heme Peroxidases PDF Author: Emma Raven
Publisher: Royal Society of Chemistry
ISBN: 1782622624
Category : Science
Languages : en
Pages : 389

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Book Description
Heme peroxidases are widely distributed in biological systems and are involved in a wide range of processes essential for life. This book provides a comprehensive single source of information on the various aspects of heme peroxidase structure, function and mechanism of action. Chapters written and edited by worldwide experts span a range of heme peroxidases from plants, yeast, bacteria and mammals. Discussed functions of peroxidases range from cell wall synthesis, synthesis of prostaglandins, role in drug suppression of tuberculosis, and antibacterial activity. Included is a discussion of peroxidases that also act as catalases and oxygenases. Heme Peroxidases serves as an essential text for those working in industry and academia in biochemistry and metallobiology.

Biological Oxidations

Biological Oxidations PDF Author: H. Sund
Publisher: Springer Science & Business Media
ISBN: 3642694675
Category : Science
Languages : en
Pages : 318

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Thermodynamics and Biophysics of Biomedical Nanosystems

Thermodynamics and Biophysics of Biomedical Nanosystems PDF Author: Costas Demetzos
Publisher: Springer
ISBN: 9811309892
Category : Technology & Engineering
Languages : en
Pages : 475

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Book Description
This book highlights the recent advances of thermodynamics and biophysics in drug delivery nanosystems and in biomedical nanodevices. The up-to-date book provides an in-depth knowledge of bio-inspired nanotechnological systems for pharmaceutical applications. Biophysics and thermodynamics, supported by mathematics, are the locomotive by which the drug transportation and the targeting processes will be achieved under the light of the modern pharmacotherapy. They are considered as scientific tools that promote the understanding of physicochemical and thermotropic functionality and behavior of artificial cell membranes and structures like nanoparticulate systems. Therefore, this book focusses on new aspects of biophysics and thermodynamics as important elements for evaluating biomedical nanosystems, and it correlates their physicochemical, biophysical and thermodynamical behaviour with those of a living organism. In 2018, Prof. Demetzos was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology.

Iron-containing Enzymes

Iron-containing Enzymes PDF Author: Sam P. De Visser
Publisher: Royal Society of Chemistry
ISBN: 1849731810
Category : Science
Languages : en
Pages : 463

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Book Description
Mononuclear iron containing enzymes are important intermediates in bioprocesses and have potential in the industrial biosynthesis of specific products. This book features topical review chapters by leaders in this field and its various sub-disciplines.

Cytochrome P450

Cytochrome P450 PDF Author: Paul R. Ortiz de Montellano
Publisher: Springer Science & Business Media
ISBN: 0387274472
Category : Medical
Languages : en
Pages : 702

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Book Description
Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.

Computational Electrochemistry

Computational Electrochemistry PDF Author: S. Paddison
Publisher: The Electrochemical Society
ISBN: 1607686511
Category : Science
Languages : en
Pages : 49

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