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Author: Alexandre Dumas père
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
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Author: Alexandre Dumas père
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Jacqueline Mulhallen
Publisher: Open Book Publishers
ISBN: 1906924309
Category : Literary Criticism
Languages : en
Pages : 310
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Book Description
Based on the author's thesis (Ph.D., Anglia Ruskin University).
Author: John M. Swales
Publisher: University of Michigan Press ELT
ISBN:
Category : Foreign Language Study
Languages : en
Pages : 272
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Book Description
A Course for Nonnative Speakers of English. Genre-based approach. Includes units such as graphs and commenting on other data and research papers.
Author: Samuel Hawkins Marshall Byers
Publisher:
ISBN:
Category : History
Languages : en
Pages : 392
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Author: Rose Hawthorne Lathrop
Publisher:
ISBN:
Category : Literary Criticism
Languages : en
Pages : 510
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Book Description
This is a pre-1923 historical reproduction that was curated for quality. Quality assurance was conducted on each of these books in an attempt to remove books with imperfections introduced by the digitization process. Though we have made best efforts - the books may have occasional errors that do not impede the reading experience. We believe this work is culturally important and have elected to bring the book back into print as part of our continuing commitment to the preservation of printed works worldwide.
Author: John Pendleton Kennedy
Publisher:
ISBN:
Category : American fiction
Languages : en
Pages : 622
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Author: George Parsons Lathrop
Publisher:
ISBN:
Category : Literary Criticism
Languages : en
Pages : 356
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Book Description
This is a pre-1923 historical reproduction that was curated for quality. Quality assurance was conducted on each of these books in an attempt to remove books with imperfections introduced by the digitization process. Though we have made best efforts - the books may have occasional errors that do not impede the reading experience. We believe this work is culturally important and have elected to bring the book back into print as part of our continuing commitment to the preservation of printed works worldwide.
Author: Rita Sattler
Publisher: Springer
ISBN: 331989689X
Category : Medical
Languages : en
Pages : 321
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Book Description
It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi--‐directional transcription and production of repeat associated non--‐ATG (RAN) translation products. This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways.
Author: Julian Hawthorne
Publisher:
ISBN:
Category : Novelists, American
Languages : en
Pages : 468
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Book Description
Author: Zhou Xuedong
Publisher: Springer
ISBN: 3662474506
Category : Medical
Languages : en
Pages : 187
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Book Description
This book is a well-illustrated and comprehensive guide to the etiology, clinical manifestations, diagnosis, clinical management and prevention of dental caries. Current challenging problems in the field are analyzed and the latest research findings, presented. After an introductory chapter on tooth development, the relationships of biofilm and saliva to dental caries and the significance of the balance between demineralization and remineralization for the development of carious lesions are discussed. Subsequent chapters address the state of the art in diagnosis and treatment, the implications of disease burden for prevention and the association between systemic diseases and dental caries. Dental Caries: Principles and Management is intended for dental school students, practicing dentists and researchers in dentistry.
