Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases

Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases PDF Author:
Publisher: Academic Press
ISBN: 0128215240
Category : Science
Languages : en
Pages : 332

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Book Description
Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis, Volume 87, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in "Current Topics in Membranes" series - Updated release includes the latest information on Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis

Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases

Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases PDF Author:
Publisher: Academic Press
ISBN: 0128215240
Category : Science
Languages : en
Pages : 332

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Book Description
Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis, Volume 87, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in "Current Topics in Membranes" series - Updated release includes the latest information on Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis

Biochemistry and Cell Biology of Ageing: Part I Biomedical Science

Biochemistry and Cell Biology of Ageing: Part I Biomedical Science PDF Author: J. Robin Harris
Publisher: Springer
ISBN: 9811328358
Category : Medical
Languages : en
Pages : 531

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Book Description
This new volume in the Subcellular Biochemistry series will focus on the biochemistry and cellular biology of aging processes in human cells. The chapters will be written by experts in their respective fields and will focus on a number of the current key areas of research in subcellular aging research. Main topics for discussion are mitochondrial aging, protein homeostasis and aging and the genetic processes that are involved in aging. There will also be chapters that are dedicated to the study of the roles of a variety of vitamins and minerals on aging and a number of other external factors (microbiological, ROS, inflammation, nutrition). This book will provide the reader with a state of the art overview of the subcellular aging field. This book will be published in cooperation with a second volume that will discuss the translation of the cell biology of aging to a more clinical setting and it is hoped that the combination of these two volumes will bring a deeper understanding of the links between the cell and the body during aging.

Biomechanics

Biomechanics PDF Author: Y. C. Fung
Publisher: Springer Science & Business Media
ISBN: 1475717520
Category : Medical
Languages : en
Pages : 443

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Book Description
The motivation for writing aseries ofbooks on biomechanics is to bring this rapidly developing subject to students of bioengineering, physiology, and mechanics. In the last decade biomechanics has become a recognized disci pline offered in virtually all universities. Yet there is no adequate textbook for instruction; neither is there a treatise with sufficiently broad coverage. A few books bearing the title of biomechanics are too elementary, others are too specialized. I have long feIt a need for a set of books that will inform students of the physiological and medical applications of biomechanics, and at the same time develop their training in mechanics. We cannot assume that all students come to biomechanics already fully trained in fluid and solid mechanics; their knowledge in these subjects has to be developed as the course proceeds. The scheme adopted in the present series is as follows. First, some basic training in mechanics, to a level about equivalent to the first seven chapters of the author's A First Course in Continuum Mechanics (Prentice-Hall,lnc. 1977), is assumed. We then present some essential parts of biomechanics from the point of view of bioengineering, physiology, and medical applications. In the meantime, mechanics is developed through a sequence of problems and examples. The main text reads like physiology, while the exercises are planned like a mechanics textbook. The instructor may fil1 a dual role: teaching an essential branch of life science, and gradually developing the student's knowledge in mechanics.

Current Topics in Membranes

Current Topics in Membranes PDF Author:
Publisher: Academic Press
ISBN: 0080585108
Category : Science
Languages : en
Pages : 477

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Book Description
Current Topics in Membranes

Pathogenic Mechanisms in Cardiac and Skeletal Muscle Diseases

Pathogenic Mechanisms in Cardiac and Skeletal Muscle Diseases PDF Author: Marcella Canton
Publisher: Frontiers Media SA
ISBN: 2889717267
Category : Science
Languages : en
Pages : 191

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Book Description


Calcific Aortic Valve Disease

Calcific Aortic Valve Disease PDF Author: Elena Aikawa
Publisher: BoD – Books on Demand
ISBN: 9535111507
Category : Medical
Languages : en
Pages : 544

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Book Description
Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Mechanosensitive Ion Channels, Part B

Mechanosensitive Ion Channels, Part B PDF Author:
Publisher: Elsevier
ISBN: 0080494404
Category : Science
Languages : en
Pages : 610

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Book Description
Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include ENaC Proteins in Vascular Smooth Muscle Mechanotransduction; Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids; MechanoTRPs and TRPA1; TRPC; The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism. Lessons From Polycystin-2 (TRPP2); Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels; Hair Cell Mechanotransduction: The Dynamic Interplay between Structure and Function; Pharmacology of Hair Cell MS Channels; Hair Cell Mechanotransduction; Models of Hair Cell Mechanotrasduction; Touch; Mechanosensitive Ion Channels in Dystrophic Muscle; Mechanotransduction in Endothelial Cells;MS Channels in Tumor Cell Migration; Mechanosensitive Channels in Regulating Smooth Muscle Contraction in the GI; Mechanosensitive Ion Channels in Blood-Pressure-Sensing Baroreceptor Neurons.

Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis

Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis PDF Author: Ralf Weiskirchen
Publisher: MDPI
ISBN: 3039361880
Category : Medical
Languages : en
Pages : 276

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Book Description
Worldwide, liver fibrosis is a major cause of morbidity and mortality and is associated with a high medical and economic burden. It is the common consequence of chronic liver injury due to various etiologies. During fibrogenesis, there is a progressive substitution of the liver parenchyma by scar tissue. Recent advances in the understanding of the history of liver fibrosis have shown that the pathogenesis is driven by different cell types and a large variety of soluble mediators. At present, scientists working in this field aim to increase basic knowledge, improve diagnostics, and try to translate experimental findings into new treatment modalities. This book includes 12 selected contributions from the Special Issue “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis” that was published in Cells. These articles summarize current perspectives and findings in hepatic fibrosis research showing how scientists try to use basic scientific research to create new therapies and diagnostics.

Mechanobiology at multiple scales

Mechanobiology at multiple scales PDF Author: Yuhui Li
Publisher: Frontiers Media SA
ISBN: 2832528422
Category : Science
Languages : en
Pages : 129

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Book Description


Mechanobiology in Health and Disease

Mechanobiology in Health and Disease PDF Author: Stefaan Verbruggen
Publisher: Academic Press
ISBN: 0128129530
Category : Medical
Languages : en
Pages : 530

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Book Description
Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. - Provides an essential digest of primary research from many fields and disciplines in one convenient volume - Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives - Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science