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Author: Ji Sungchul
Publisher: World Scientific
ISBN: 1911299778
Category : Science
Languages : en
Pages : 612
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Book Description
This book represents the results of 45 years of research on a wide range of topics, including atomic physics, single-molecule enzymology, whole-cell metabolism, physiology, pharmacology, linguistics, semiotics, and cosmology. It describes the first comprehensive molecular theory of the genotype-phenotype coupling based on two key theoretical concepts: (i) the conformon, the conformational wave packet in biopolymers carrying both the free energy and genetic information; and (ii) the intracellular dissipative structures, the chemical concentration waves inside the cell that serve as the immediate drivers of all cell functions. Conformons provide the driving forces for all molecular machines in the cell, and intracellular dissipative structures coordinate intra- and intercellular processes such as gene expression and cell-cell communications. One of the predictions made by the cell language theory (CLT) is that there are two forms of genetic information — the Watson–Crick genes transmitting information in time (identified with DNA), and the Prigoginian genes transmitting information in space (identified with RNA expression profiles). The former is analogous to sheet music or written language and the latter is akin to audio music or spoken language, both being coupled by conformons acting as the analog of the pianist. The new theory of DNA structure and function constructed on the basis of CLT can rationally account for most of the puzzling findings recently unearthed by the ENCODE (Encyclopedia of DNA Elements) project. The Cell Language Theory has important applications in biomedical sciences including drug discovery research and personalized medicine on the one hand and in the mind-body research and consciousness studies on the other. Contents: PrefaceAbout the AuthorAcknowledgementsIntroductionKey Terms and ConceptsThe BhopalatorCell LanguageMatrix Mathematics of GeneticsBiosemioticsApplications of the Cell Language Theory to Biomedical SciencesThe Universality of the Planckian Distribution EquationThe Universality of the Irreducible Triadic RelationThe Philosophical Implications of the Cell Language TheoryConclusionsReferencesAppendicesIndex Readership: Students, researchers and practitioners of the biomedical sciences and mind-body research and consciousness studies Keywords: Conformons;Cell Language Theory;Intracellular Dissipative Structures;Watson-Crick Gene;Prigoginian GeneReview:0
Author: Ji Sungchul
Publisher: World Scientific
ISBN: 1911299778
Category : Science
Languages : en
Pages : 612
Get Book
Book Description
This book represents the results of 45 years of research on a wide range of topics, including atomic physics, single-molecule enzymology, whole-cell metabolism, physiology, pharmacology, linguistics, semiotics, and cosmology. It describes the first comprehensive molecular theory of the genotype-phenotype coupling based on two key theoretical concepts: (i) the conformon, the conformational wave packet in biopolymers carrying both the free energy and genetic information; and (ii) the intracellular dissipative structures, the chemical concentration waves inside the cell that serve as the immediate drivers of all cell functions. Conformons provide the driving forces for all molecular machines in the cell, and intracellular dissipative structures coordinate intra- and intercellular processes such as gene expression and cell-cell communications. One of the predictions made by the cell language theory (CLT) is that there are two forms of genetic information — the Watson–Crick genes transmitting information in time (identified with DNA), and the Prigoginian genes transmitting information in space (identified with RNA expression profiles). The former is analogous to sheet music or written language and the latter is akin to audio music or spoken language, both being coupled by conformons acting as the analog of the pianist. The new theory of DNA structure and function constructed on the basis of CLT can rationally account for most of the puzzling findings recently unearthed by the ENCODE (Encyclopedia of DNA Elements) project. The Cell Language Theory has important applications in biomedical sciences including drug discovery research and personalized medicine on the one hand and in the mind-body research and consciousness studies on the other. Contents: PrefaceAbout the AuthorAcknowledgementsIntroductionKey Terms and ConceptsThe BhopalatorCell LanguageMatrix Mathematics of GeneticsBiosemioticsApplications of the Cell Language Theory to Biomedical SciencesThe Universality of the Planckian Distribution EquationThe Universality of the Irreducible Triadic RelationThe Philosophical Implications of the Cell Language TheoryConclusionsReferencesAppendicesIndex Readership: Students, researchers and practitioners of the biomedical sciences and mind-body research and consciousness studies Keywords: Conformons;Cell Language Theory;Intracellular Dissipative Structures;Watson-Crick Gene;Prigoginian GeneReview:0
Author: Sungchul Ji
Publisher: Wspc (Europe)
ISBN: 9781848166608
Category : Science
Languages : en
Pages : 300
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Book Description
This book describes the first molecular theory of the genotype-phenotype coupling (or cell language) based on two key concepts: (i) the conformon, the packet of free energy and genetic information stored in biopolymers; and (ii) the intracellular dissipative structures, the concentration gradients in the cell that drive all cell functions. Conformons provide the driving forces for all molecular machines in the cell including ATP-dependent chromatin remodeling proteins, and dissipative structures coordinate cell-wide processes such as gene expression and cell cycle. One prediction of the new theory is that there are two forms of genetic information the WatsonCrick genes transmitting information in time (identified with DNA), and the Prigoginian genes transmitting information in space (identified with RNA expression profiles). The former is analogous to sheet music or written language, the latter is akin to audio music or spoken language, and conformons act as the pianist. The new theory of DNA structure and function can rationally account for most of the puzzling findings recently unearthed by the ENCODE (Encyclopedia of DNA Elements) project. The cell language theory described in this book, coupled with high-throughput experimental data and computational methods, is expected to facilitate the practical applications of cell biological knowledge to biomedical sciences, including diagnosis, therapeutics, and drug discovery.
Author: Mark Burgin
Publisher: World Scientific
ISBN: 9813277505
Category : Computers
Languages : en
Pages : 534
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Book Description
This is the first attempt to delineate the synthetic field of the theoretical study of information, treating information as the basic phenomenon on the fundamental level of the world, encompassing nature, technology, individuals and society. The exploration of information is done within Info-computational approaches, to natural and social phenomena such as Bioinformatics, Information Physics, Informational Chemistry, Computational Physics, Cognitive and Social sciences, with special emphasis on interdisciplinary, crossdisciplinary and transdisciplinary knowledge.The book presents results of collaboration across research fields within info-computational and info-structural frameworks, in attempt to better theoretically and conceptually capture the phenomenon of information and its dynamics (such as computation and communication), as they appear on different levels of organization, on different scales and in different contexts.
Author: Noury Bakrim
Publisher: BoD - Books on Demand
ISBN: 2322376590
Category : Language Arts & Disciplines
Languages : en
Pages : 68
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Book Description
In addition of proposing a model of language based on a bio-mathematical reduction within a synthesis between deduction, induction it suggests a much more important role of learning symmetry (especially iconicity) parallel to Universal Grammar. Without any theoretical megalomania, the model you will be discovering, reading and hopefully discussing hypothesizes two propositional principles with an important role of thermodynamic information : the shift from the bio-semiotic to the semiotic order along with the neural/dynamic mapping is embedded in the shift from thermodynamic laws without proposition (methodologically defined by hypothetic-probabilistic states of the ''internal observer'', Boltzmann-Bernoulli proposals and quantization) to biological and cultural consciousness (selection, combination, self-reference and symmetry etc etc)
Author: Zhengbing Hu
Publisher: Springer
ISBN: 3030120821
Category : Technology & Engineering
Languages : en
Pages : 787
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Book Description
This book includes the proceedings of the Second International Conference of Artificial Intelligence, Medical Engineering, Education (AIMEE2018), held in Moscow, Russia, on 6–8 October 2018. The conference covered advances in the development of artificial intelligence systems and their applications in various fields, from medicine and technology to education. The papers presented in the book discuss topics in mathematics and biomathematics; medical approaches; and technological and educational approaches. Given the rapid development of artificial intelligence systems, the book highlights the need for more intensive training for a growing number of specialists, particularly in medical engineering, to increase the effectiveness of medical diagnosis and treatment. The book is intended for specialists, students and other readers who would like to know where artificial intelligence systems can beneficially be applied in the future.
Author: Noury Bakrim
Publisher: BoD - Books on Demand
ISBN: 2322517097
Category : Mathematics
Languages : en
Pages : 70
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Book Description
This book is the third component in the ROAL model; it suggests a relation between language and mathematical models of totality relying on verifiability and observability/objectivity models of the linguistic text. In addition of the biomathematical hypothesis, rules of observability and objectivity have been extended to both objective and non-objective models toward a manifolded dimension of the structure within a field dimension of consciousness in which dwells the paradigm of the text as a meta-observability domain for language and natural/individual languages.
Author: Burgin Mark
Publisher: World Scientific
ISBN: 9813109041
Category : Language Arts & Disciplines
Languages : en
Pages : 412
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Book Description
The book is a collection of papers of experts in the fields of information and complexity. Information is a basic structure of the world, while complexity is a fundamental property of systems and processes. There are intrinsic relations between information and complexity. The research in information theory, the theory of complexity and their interrelations is very active. The book will expand knowledge on information, complexity and their relations representing the most recent and advanced studies and achievements in this area. The goal of the book is to present the topic from different perspectives — mathematical, informational, philosophical, methodological, etc.
Author: Fritjof Capra
Publisher: University of New Mexico Press
ISBN: 0826362818
Category : Science
Languages : en
Pages : 494
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Book Description
Fritjof Capra, scientist, educator, activist, and accomplished author, presents the evolution of his thought over five decades in Patterns of Connection. First introduced in the late 1950s to the work of Werner Heisenberg, a founder of quantum mechanics, Capra quickly intuited the connections between the discoveries of quantum physics and the traditions of Eastern philosophy—resulting in his first book, the bestselling The Tao of Physics. This synthesis, representative of the change from the mechanistic worldview of Descartes and Newton to a systemic, ecological one, went on to inform Capra’s thinking about the life sciences, ecology, and environmental policy. Today Fritjof Capra remains a major figure at the crossroads of physics, spirituality, environmentalism, and systems theory. Organized thematically and chronologically, the essays in Patterns of Connection document the revolutionary and far-reaching intellectual journey of one of the major public thinkers of the last half-century.
Author: Fritjof Capra
Publisher: Cambridge University Press
ISBN: 1107011361
Category : Business & Economics
Languages : en
Pages : 513
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Book Description
The first volume to integrate life's biological, cognitive, social, and ecological dimensions into a single, coherent framework.
Author: Jon Lieff
Publisher: BenBella Books
ISBN: 1948836335
Category : Science
Languages : en
Pages : 325
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Book Description
Your cells are talking about you. Right now, both your inner and outer worlds are abuzz with chatter among living cells of every possible kind—from those in your body and brain to those in the environment around you. From electrical alerts to chemical codes, the greatest secret of modern biology, hiding in plain sight, is that all of life's activity boils down to one thing: conversation. While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer. He explains the surprising science of how very different cells—bacteria and brain cells, blood cells and viruses—all speak the same language. This overarching principle has been long overlooked because scientific journals use impenetrable jargon that makes it hard to be understood across disciplines, much less by the general public. Lieff presents a fascinating and accessible look into cellular communication science—a groundbreaking and comprehensive exploration of this biological phenomenon. In these pages, discover the intriguing lives of cells as they ask questions, get answers, give feedback, gather information, call for each other, and make complex decisions. During infections, immune T-cells tell brain cells that we should "feel sick" and lie down. Cancer cells warn their community about immune and microbe attacks. Gut cells talk with microbes to determine which are friends and which are enemies, and microbes talk with each other and with much more complicated human cells in ways that determine which medicines work and which will fail. With applications for immunity, chronic pain, weight loss, depression, cancer treatment, and virtually every aspect of health and biology, cellular communication is revolutionizing our understanding not just of disease, but of life itself. The Secret Language of Cells is required reading for anyone interested in following the conversation.
