Author: Alan R. Thornhill
Publisher: Springer Science & Business Media
ISBN: 159745298X
Category : Science
Languages : en
Pages : 185
Book Description
This book applies modern molecular diagnostic techniques to the analysis of single cells, small numbers of cells, or cell extracts. Emphasis is placed on non-invasive analysis of single cell metabolites and the direct analysis of RNA and DNA from single cells, with a focus on polymerase chain reaction and fluorescence in situ hybridization. In particular, this handbook is essential for practitioners providing care for couples seeking treatment for infertility.
Single Cell Diagnostics
Author: Alan R. Thornhill
Publisher: Springer Science & Business Media
ISBN: 159745298X
Category : Science
Languages : en
Pages : 185
Book Description
This book applies modern molecular diagnostic techniques to the analysis of single cells, small numbers of cells, or cell extracts. Emphasis is placed on non-invasive analysis of single cell metabolites and the direct analysis of RNA and DNA from single cells, with a focus on polymerase chain reaction and fluorescence in situ hybridization. In particular, this handbook is essential for practitioners providing care for couples seeking treatment for infertility.
Publisher: Springer Science & Business Media
ISBN: 159745298X
Category : Science
Languages : en
Pages : 185
Book Description
This book applies modern molecular diagnostic techniques to the analysis of single cells, small numbers of cells, or cell extracts. Emphasis is placed on non-invasive analysis of single cell metabolites and the direct analysis of RNA and DNA from single cells, with a focus on polymerase chain reaction and fluorescence in situ hybridization. In particular, this handbook is essential for practitioners providing care for couples seeking treatment for infertility.
Cell Diagnostics
Author: V V Roshchina
Publisher: CRC Press
ISBN: 1482280558
Category : Science
Languages : en
Pages : 224
Book Description
Topics discussed in this title include cellular model systems, new methods of microscopy in cellular diagnostics and methods of analytical biochemistry and biophysics.
Publisher: CRC Press
ISBN: 1482280558
Category : Science
Languages : en
Pages : 224
Book Description
Topics discussed in this title include cellular model systems, new methods of microscopy in cellular diagnostics and methods of analytical biochemistry and biophysics.
Advances in Cell and Molecular Diagnostics
Author: P.B. Raghavendra
Publisher: Academic Press
ISBN: 0128136804
Category : Science
Languages : en
Pages : 300
Book Description
Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare. - Encompasses the current scientific advances in the translation and validation of cellular and molecular discoveries into the clinical diagnostic setting - Explains the application of cellular and molecular diagnostics methodologies in clinical trials - Focuses on translating preclinical tests to the bedside in order to help readers apply the most recent technologies to healthcare
Publisher: Academic Press
ISBN: 0128136804
Category : Science
Languages : en
Pages : 300
Book Description
Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare. - Encompasses the current scientific advances in the translation and validation of cellular and molecular discoveries into the clinical diagnostic setting - Explains the application of cellular and molecular diagnostics methodologies in clinical trials - Focuses on translating preclinical tests to the bedside in order to help readers apply the most recent technologies to healthcare
Cellular Diagnostics
Author: Ulrich Sack
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805585551
Category : Medical
Languages : en
Pages : 764
Book Description
This book is the updated English version of the 2006 German bestseller Zellulare Diagnostik, a comprehensive presentation of flow cytometry and its applications. While some techniques of immunophenotyping by flow cytometry already are routine procedures in the laboratory, new methods for the functional characterization of cells, the analysis of rare cells, and the diagnosis of complex materials have only begun to win wide recognition. New approaches such as slide-based cytometry will lead to an increase in the use of cytometric techniques. Multiparameter approaches will further improve analysis. The book provides a comprehensive and detailed compilation of all aspects of flow cytometry in research and the clinic. For newcomers it offers a thorough introduction, for advanced users, specific protocols and interpretation assistance.
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805585551
Category : Medical
Languages : en
Pages : 764
Book Description
This book is the updated English version of the 2006 German bestseller Zellulare Diagnostik, a comprehensive presentation of flow cytometry and its applications. While some techniques of immunophenotyping by flow cytometry already are routine procedures in the laboratory, new methods for the functional characterization of cells, the analysis of rare cells, and the diagnosis of complex materials have only begun to win wide recognition. New approaches such as slide-based cytometry will lead to an increase in the use of cytometric techniques. Multiparameter approaches will further improve analysis. The book provides a comprehensive and detailed compilation of all aspects of flow cytometry in research and the clinic. For newcomers it offers a thorough introduction, for advanced users, specific protocols and interpretation assistance.
Chemical Diagnostics
Author: Nelson L.S. Tang
Publisher: Springer
ISBN: 3642399428
Category : Science
Languages : en
Pages : 204
Book Description
Next Generation Sequencing: Chemistry, Technology and Applications, by P. Hui Application of Next Generation Sequencing to Molecular Diagnosis of Inherited Diseases, by W. Zhang, H. Cui, L.-J.C. Wong Clinical Applications of the Latest Molecular Diagnostics in Noninvasive Prenatal Diagnosis, by K.C.A. Chan The Role of Protein Structural Analysis in the Next Generation Sequencing Era, by W.W. Yue, D.S. Froese, P.E. Brennan Emerging Applications of Single-Cell Diagnostics, by M. Shirai, T. Taniguchi, H. Kambara Mass Spectrometry in High-Throughput Clinical Biomarker Assays: Multiple Reaction Monitoring, by C.E. Parker, D. Domanski, A.J. Percy, A.G. Chambers, A.G. Camenzind, D.S. Smith, C.H. Borchers Advances in MALDI Mass Spectrometry in Clinical Diagnostic Applications, by E.W.Y. Ng, M.Y.M. Wong, T.C.W. Poon Application of Mass Spectrometry in Newborn Screening: About Both Small Molecular Diseases and Lysosomal Storage Diseases, by W.-L. Hwu, Y.-H. Chien, N.-C. Lee, S.-F. Wang, S.-C. Chiang, L.-W. Hsu
Publisher: Springer
ISBN: 3642399428
Category : Science
Languages : en
Pages : 204
Book Description
Next Generation Sequencing: Chemistry, Technology and Applications, by P. Hui Application of Next Generation Sequencing to Molecular Diagnosis of Inherited Diseases, by W. Zhang, H. Cui, L.-J.C. Wong Clinical Applications of the Latest Molecular Diagnostics in Noninvasive Prenatal Diagnosis, by K.C.A. Chan The Role of Protein Structural Analysis in the Next Generation Sequencing Era, by W.W. Yue, D.S. Froese, P.E. Brennan Emerging Applications of Single-Cell Diagnostics, by M. Shirai, T. Taniguchi, H. Kambara Mass Spectrometry in High-Throughput Clinical Biomarker Assays: Multiple Reaction Monitoring, by C.E. Parker, D. Domanski, A.J. Percy, A.G. Chambers, A.G. Camenzind, D.S. Smith, C.H. Borchers Advances in MALDI Mass Spectrometry in Clinical Diagnostic Applications, by E.W.Y. Ng, M.Y.M. Wong, T.C.W. Poon Application of Mass Spectrometry in Newborn Screening: About Both Small Molecular Diseases and Lysosomal Storage Diseases, by W.-L. Hwu, Y.-H. Chien, N.-C. Lee, S.-F. Wang, S.-C. Chiang, L.-W. Hsu
PEM Fuel Cells
Author: Frano Barbir
Publisher: Academic Press
ISBN: 0123877105
Category : Science
Languages : en
Pages : 537
Book Description
Demand for fuel cell technology is growing rapidly. Fuel cells are being commercialized to provide power to buildings like hospitals and schools, to replace batteries in portable electronic devices, and as replacements for internal combustion engines in vehicles. PEM (Proton Exchange Membrane) fuel cells are lighter, smaller, and more efficient than other types of fuel cell. As a result, over 80% of fuel cells being produced today are PEM cells. This new edition of Dr. Barbir's groundbreaking book still lays the groundwork for engineers, technicians and students better than any other resource, covering fundamentals of design, electrochemistry, heat and mass transport, as well as providing the context of system design and applications. Yet it now also provides invaluable information on the latest advances in modeling, diagnostics, materials, and components, along with an updated chapter on the evolving applications areas wherein PEM cells are being deployed. Comprehensive guide covers all aspects of PEM fuel cells, from theory and fundamentals to practical applications Provides solutions to heat and water management problems engineers must face when designing and implementing PEM fuel cells in systems Hundreds of original illustrations, real-life engineering examples, and end-of-chapter problems help clarify, contextualize, and aid understanding
Publisher: Academic Press
ISBN: 0123877105
Category : Science
Languages : en
Pages : 537
Book Description
Demand for fuel cell technology is growing rapidly. Fuel cells are being commercialized to provide power to buildings like hospitals and schools, to replace batteries in portable electronic devices, and as replacements for internal combustion engines in vehicles. PEM (Proton Exchange Membrane) fuel cells are lighter, smaller, and more efficient than other types of fuel cell. As a result, over 80% of fuel cells being produced today are PEM cells. This new edition of Dr. Barbir's groundbreaking book still lays the groundwork for engineers, technicians and students better than any other resource, covering fundamentals of design, electrochemistry, heat and mass transport, as well as providing the context of system design and applications. Yet it now also provides invaluable information on the latest advances in modeling, diagnostics, materials, and components, along with an updated chapter on the evolving applications areas wherein PEM cells are being deployed. Comprehensive guide covers all aspects of PEM fuel cells, from theory and fundamentals to practical applications Provides solutions to heat and water management problems engineers must face when designing and implementing PEM fuel cells in systems Hundreds of original illustrations, real-life engineering examples, and end-of-chapter problems help clarify, contextualize, and aid understanding
PEM Fuel Cell Testing and Diagnosis
Author: Jiujun Zhang
Publisher: Newnes
ISBN: 0444536892
Category : Technology & Engineering
Languages : en
Pages : 391
Book Description
PEM Fuel Cell Testing and Diagnosis covers the recent advances in PEM (proton exchange membrane) fuel cell systems, focusing on instruments and techniques for testing and diagnosis, and the application of diagnostic techniques in practical tests and operation. This book is a unique source of electrochemical techniques for researchers, scientists and engineers working in the area of fuel cells. Proton exchange membrane fuel cells are currently considered the most promising clean energy-converting devices for stationary, transportation, and micro-power applications due to their high energy density, high efficiency, and environmental friendliness. To advance research and development of this emerging technology, testing and diagnosis are an essential combined step. This book aids those efforts, addressing effects of humidity, temperature and pressure on fuel cells, degradation and failure analysis, and design and assembly of MEAs, single cells and stacks. - Provides fundamental and theoretical principles for PEM fuel cell testing and diagnosis. - Comprehensive source for selecting techniques, experimental designs and data analysis - Analyzes PEM fuel cell degradation and failure mechanisms, and suggests failure mitigation strategies - Provides principles for selecting PEM fuel cell key materials to improve durability
Publisher: Newnes
ISBN: 0444536892
Category : Technology & Engineering
Languages : en
Pages : 391
Book Description
PEM Fuel Cell Testing and Diagnosis covers the recent advances in PEM (proton exchange membrane) fuel cell systems, focusing on instruments and techniques for testing and diagnosis, and the application of diagnostic techniques in practical tests and operation. This book is a unique source of electrochemical techniques for researchers, scientists and engineers working in the area of fuel cells. Proton exchange membrane fuel cells are currently considered the most promising clean energy-converting devices for stationary, transportation, and micro-power applications due to their high energy density, high efficiency, and environmental friendliness. To advance research and development of this emerging technology, testing and diagnosis are an essential combined step. This book aids those efforts, addressing effects of humidity, temperature and pressure on fuel cells, degradation and failure analysis, and design and assembly of MEAs, single cells and stacks. - Provides fundamental and theoretical principles for PEM fuel cell testing and diagnosis. - Comprehensive source for selecting techniques, experimental designs and data analysis - Analyzes PEM fuel cell degradation and failure mechanisms, and suggests failure mitigation strategies - Provides principles for selecting PEM fuel cell key materials to improve durability
PEM Fuel Cell Diagnostic Tools
Author: Haijiang Wang
Publisher: CRC Press
ISBN: 1439839190
Category : Science
Languages : en
Pages : 580
Book Description
PEM Fuel Cell Diagnostic Tools presents various tools for diagnosing PEM fuel cells and stacks, including in situ and ex situ diagnostic tools, electrochemical techniques, and physical/chemical methods. The text outlines the principles, experimental implementation, data processing, and application of each technique, along with its capabilities and weaknesses. The book covers many diagnostics employed in the characterization and determination of fuel cell performance. It discusses commonly used conventional tools, such as cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscopy, and transmission electron microscopy. It also examines special tools developed specifically for PEM fuel cells, including transparent cells, cathode discharge, and current mapping, as well as recent advanced tools for diagnosis, such as magnetic resonance imaging and atomic force microscopy. For clarity, the book splits these diagnostic methodologies into two parts—in situ and ex situ. To better understand the tools, PEM fuel cell testing is also discussed. Each self-contained chapter provides cross-references to other chapters. Written by international scientists active in PEM fuel cell research, this volume incorporates state-of-the-art technical advances in PEM fuel cell diagnosis. The diagnostic tools presented help readers to understand the physical and chemical phenomena involved in PEM fuel cells.
Publisher: CRC Press
ISBN: 1439839190
Category : Science
Languages : en
Pages : 580
Book Description
PEM Fuel Cell Diagnostic Tools presents various tools for diagnosing PEM fuel cells and stacks, including in situ and ex situ diagnostic tools, electrochemical techniques, and physical/chemical methods. The text outlines the principles, experimental implementation, data processing, and application of each technique, along with its capabilities and weaknesses. The book covers many diagnostics employed in the characterization and determination of fuel cell performance. It discusses commonly used conventional tools, such as cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscopy, and transmission electron microscopy. It also examines special tools developed specifically for PEM fuel cells, including transparent cells, cathode discharge, and current mapping, as well as recent advanced tools for diagnosis, such as magnetic resonance imaging and atomic force microscopy. For clarity, the book splits these diagnostic methodologies into two parts—in situ and ex situ. To better understand the tools, PEM fuel cell testing is also discussed. Each self-contained chapter provides cross-references to other chapters. Written by international scientists active in PEM fuel cell research, this volume incorporates state-of-the-art technical advances in PEM fuel cell diagnosis. The diagnostic tools presented help readers to understand the physical and chemical phenomena involved in PEM fuel cells.
Stem Cell Bioprocessing
Author: Tiago G. Fernandes
Publisher: Elsevier
ISBN: 1908818301
Category : Science
Languages : en
Pages : 236
Book Description
Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. - Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approaches - Envisages the use of stem cells in regenerative medicine and drug screening applications - Discusses the application of microscale techniques as a tool to perform basic stem cell biology studies
Publisher: Elsevier
ISBN: 1908818301
Category : Science
Languages : en
Pages : 236
Book Description
Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. - Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approaches - Envisages the use of stem cells in regenerative medicine and drug screening applications - Discusses the application of microscale techniques as a tool to perform basic stem cell biology studies
Molecular Diagnostics
Author: Wayne W. Grody
Publisher: Academic Press
ISBN: 0080919049
Category : Medical
Languages : en
Pages : 518
Book Description
Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. - Serves as the definitivereference for molecular pathologists worldwide - Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics - Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science
Publisher: Academic Press
ISBN: 0080919049
Category : Medical
Languages : en
Pages : 518
Book Description
Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. - Serves as the definitivereference for molecular pathologists worldwide - Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics - Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science