Author: National Research Council
Publisher: National Academies Press
ISBN: 030909612X
Category : Science
Languages : en
Pages : 469
Book Description
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Catalyzing Inquiry at the Interface of Computing and Biology
Author: National Research Council
Publisher: National Academies Press
ISBN: 030909612X
Category : Science
Languages : en
Pages : 469
Book Description
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Publisher: National Academies Press
ISBN: 030909612X
Category : Science
Languages : en
Pages : 469
Book Description
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Globalization, Biosecurity, and the Future of the Life Sciences
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309100321
Category : Science
Languages : en
Pages : 317
Book Description
Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways-leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.
Publisher: National Academies Press
ISBN: 0309100321
Category : Science
Languages : en
Pages : 317
Book Description
Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways-leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.
Bioinformational Philosophy and Postdigital Knowledge Ecologies
Author: Michael A. Peters
Publisher: Springer Nature
ISBN: 3030950069
Category : Education
Languages : en
Pages : 367
Book Description
The book presents a cross-disciplinary overview of critical issues at the intersections of biology, information, and society. Based on theories of bioinformationalism, viral modernity, the postdigital condition, and others, this book explores two inter-related questions: Which new knowledge ecologies are emerging? Which philosophies and research approaches do they require? The book argues that the 20th century focus on machinery needs to be replaced, at least partially, by a focus on a better understanding of living systems and their interactions with technology at all scales – from viruses, through to human beings, to the Earth’s ecosystem. This change of direction cannot be made by a simple relocation of focus and/or funding from one discipline to another. In our age of the Anthropocene, (human and planetary) biology cannot be thought of without (digital) technology and society. Today’s curious bioinformational mix of blurred and messy relationships between physics and biology, old and new media, humanism and posthumanism, knowledge capitalism and bio-informational capitalism defines the postdigital condition and creates new knowledge ecologies. The book presents scholarly research defining new knowledge ecologies built upon emerging forms of scientific communication, big data deluge, and opacity of algorithmic operations. Many of these developments can be approached using the concept of viral modernity, which applies to viral technologies, codes and ecosystems in information, publishing, education, and emerging knowledge (journal) systems. It is within these overlapping theories and contexts, that this book explores new bioinformational philosophies and postdigital knowledge ecologies.
Publisher: Springer Nature
ISBN: 3030950069
Category : Education
Languages : en
Pages : 367
Book Description
The book presents a cross-disciplinary overview of critical issues at the intersections of biology, information, and society. Based on theories of bioinformationalism, viral modernity, the postdigital condition, and others, this book explores two inter-related questions: Which new knowledge ecologies are emerging? Which philosophies and research approaches do they require? The book argues that the 20th century focus on machinery needs to be replaced, at least partially, by a focus on a better understanding of living systems and their interactions with technology at all scales – from viruses, through to human beings, to the Earth’s ecosystem. This change of direction cannot be made by a simple relocation of focus and/or funding from one discipline to another. In our age of the Anthropocene, (human and planetary) biology cannot be thought of without (digital) technology and society. Today’s curious bioinformational mix of blurred and messy relationships between physics and biology, old and new media, humanism and posthumanism, knowledge capitalism and bio-informational capitalism defines the postdigital condition and creates new knowledge ecologies. The book presents scholarly research defining new knowledge ecologies built upon emerging forms of scientific communication, big data deluge, and opacity of algorithmic operations. Many of these developments can be approached using the concept of viral modernity, which applies to viral technologies, codes and ecosystems in information, publishing, education, and emerging knowledge (journal) systems. It is within these overlapping theories and contexts, that this book explores new bioinformational philosophies and postdigital knowledge ecologies.
Computer Science
Author:
Publisher: PediaPress
ISBN:
Category :
Languages : en
Pages : 523
Book Description
Publisher: PediaPress
ISBN:
Category :
Languages : en
Pages : 523
Book Description
Grid Computing in Life Sciences
Author: Tin Wee Tan
Publisher: World Scientific
ISBN: 9812772502
Category : Science
Languages : en
Pages : 246
Book Description
This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences. The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science. Sample Chapter(s). Chapter 1: The Grid as a ba for Biomedical Knowledge Creation (155 KB). Contents: The Grid as a OC BaOCO for Biomedical Knowledge Creation (A Konagaya); Cyberinfrastructure for the Biological Sciences (CIBIO) (J C Wooley); Controlling the Chaos: Developing Post-Genomic Grid Infrastructures (R Sinnott & M Bayer); A Framework for Biological Analysis on the Grid (T Okumura et al.); An Architectural Design of Open Genome Services (R Umetsu et al.); Proteome Analysis Using iGAP in Gfarm (W W Li et al.); Large-Scale Simulation and Prediction of HLA-Epitope Complex Structures (A E H Png et al.); Process Integration for Bio-Manufacturing Grid (Z Q Shen et al.); and other papers. Readership: Practitioners of grid computing as applied to the life sciences, life scientists and biologists working on large computational solutions that require grid computing."
Publisher: World Scientific
ISBN: 9812772502
Category : Science
Languages : en
Pages : 246
Book Description
This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences. The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science. Sample Chapter(s). Chapter 1: The Grid as a ba for Biomedical Knowledge Creation (155 KB). Contents: The Grid as a OC BaOCO for Biomedical Knowledge Creation (A Konagaya); Cyberinfrastructure for the Biological Sciences (CIBIO) (J C Wooley); Controlling the Chaos: Developing Post-Genomic Grid Infrastructures (R Sinnott & M Bayer); A Framework for Biological Analysis on the Grid (T Okumura et al.); An Architectural Design of Open Genome Services (R Umetsu et al.); Proteome Analysis Using iGAP in Gfarm (W W Li et al.); Large-Scale Simulation and Prediction of HLA-Epitope Complex Structures (A E H Png et al.); Process Integration for Bio-Manufacturing Grid (Z Q Shen et al.); and other papers. Readership: Practitioners of grid computing as applied to the life sciences, life scientists and biologists working on large computational solutions that require grid computing."
Grid Computing In The Life Science - Proceedings Of The 2nd International Life Science Grid Workshop, Lsgrid 2005
Author: Tin Wee Tan
Publisher: World Scientific
ISBN: 9814476560
Category : Science
Languages : en
Pages : 246
Book Description
This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences.The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science.
Publisher: World Scientific
ISBN: 9814476560
Category : Science
Languages : en
Pages : 246
Book Description
This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences.The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science.
Computer-Aided Drug Design
Author: Dev Bukhsh Singh
Publisher: Springer Nature
ISBN: 9811568154
Category : Medical
Languages : en
Pages : 308
Book Description
This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.
Publisher: Springer Nature
ISBN: 9811568154
Category : Medical
Languages : en
Pages : 308
Book Description
This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.
A New Biology for the 21st Century
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309147867
Category : Science
Languages : en
Pages : 113
Book Description
Now more than ever, biology has the potential to contribute practical solutions to many of the major challenges confronting the United States and the world. A New Biology for the 21st Century recommends that a "New Biology" approach-one that depends on greater integration within biology, and closer collaboration with physical, computational, and earth scientists, mathematicians and engineers-be used to find solutions to four key societal needs: sustainable food production, ecosystem restoration, optimized biofuel production, and improvement in human health. The approach calls for a coordinated effort to leverage resources across the federal, private, and academic sectors to help meet challenges and improve the return on life science research in general.
Publisher: National Academies Press
ISBN: 0309147867
Category : Science
Languages : en
Pages : 113
Book Description
Now more than ever, biology has the potential to contribute practical solutions to many of the major challenges confronting the United States and the world. A New Biology for the 21st Century recommends that a "New Biology" approach-one that depends on greater integration within biology, and closer collaboration with physical, computational, and earth scientists, mathematicians and engineers-be used to find solutions to four key societal needs: sustainable food production, ecosystem restoration, optimized biofuel production, and improvement in human health. The approach calls for a coordinated effort to leverage resources across the federal, private, and academic sectors to help meet challenges and improve the return on life science research in general.
Algebraic Biology
Author: Hirokazu Anai
Publisher: Springer
ISBN: 3540734333
Category : Computers
Languages : en
Pages : 390
Book Description
This volume constitutes the refereed proceedings of the Second International Conference on Algebraic Biology. The conference served as an interdisciplinary forum for the presentation of research on all aspects of the application of symbolic computation in biology, including computer algebra, computational logic, and related methods. Papers also examine solutions to problems in biology using symbolic methods.
Publisher: Springer
ISBN: 3540734333
Category : Computers
Languages : en
Pages : 390
Book Description
This volume constitutes the refereed proceedings of the Second International Conference on Algebraic Biology. The conference served as an interdisciplinary forum for the presentation of research on all aspects of the application of symbolic computation in biology, including computer algebra, computational logic, and related methods. Papers also examine solutions to problems in biology using symbolic methods.
Inspired by Biology
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309117046
Category : Science
Languages : en
Pages : 171
Book Description
Scientists have long desired to create synthetic systems that function with the precision and efficiency of biological systems. Using new techniques, researchers are now uncovering principles that could allow the creation of synthetic materials that can perform tasks as precise as biological systems. To assess the current work and future promise of the biology-materials science intersection, the Department of Energy and the National Science Foundation asked the NRC to identify the most compelling questions and opportunities at this interface, suggest strategies to address them, and consider connections with national priorities such as healthcare and economic growth. This book presents a discussion of principles governing biomaterial design, a description of advanced materials for selected functions such as energy and national security, an assessment of biomolecular materials research tools, and an examination of infrastructure and resources for bridging biological and materials science.
Publisher: National Academies Press
ISBN: 0309117046
Category : Science
Languages : en
Pages : 171
Book Description
Scientists have long desired to create synthetic systems that function with the precision and efficiency of biological systems. Using new techniques, researchers are now uncovering principles that could allow the creation of synthetic materials that can perform tasks as precise as biological systems. To assess the current work and future promise of the biology-materials science intersection, the Department of Energy and the National Science Foundation asked the NRC to identify the most compelling questions and opportunities at this interface, suggest strategies to address them, and consider connections with national priorities such as healthcare and economic growth. This book presents a discussion of principles governing biomaterial design, a description of advanced materials for selected functions such as energy and national security, an assessment of biomolecular materials research tools, and an examination of infrastructure and resources for bridging biological and materials science.