Cardiac Pacemaking in Health and Disease: From Genes to Function PDF Download
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Author: Pietro Mesirca
Publisher: Frontiers Media SA
ISBN: 2889760251
Category : Science
Languages : en
Pages : 259
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Book Description
Author: Pietro Mesirca
Publisher: Frontiers Media SA
ISBN: 2889760251
Category : Science
Languages : en
Pages : 259
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Book Description
Author: Alexandre Mebazaa
Publisher: Springer Science & Business Media
ISBN: 1846287820
Category : Medical
Languages : en
Pages : 922
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Book Description
For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: Zhongjie Sun
Publisher: Springer Science & Business Media
ISBN: 159259879X
Category : Medical
Languages : en
Pages : 410
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Book Description
The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the study of heart disease pathogenesis. Methods for gene transfer to heart tissue using viral and nonviral vectors form the basis of gene therapy for heart diseases. Heart-specific promoters containing a hypox- inducible cardioprotective gene switch are key for protection of the heart from ischemia. Gene and stem cell therapies open novel and exciting avenues for the prevention and treatment of heart diseases. Molecular Cardiology: Methods and Protocols consists of 26 chapters de- ing with various aspects of molecular cardiology, including gene transfer and gene therapy for cardiovascular disease, stem cell therapy for cardiovascular disease, gene analysis in the injured and hypertrophied heart, and transgenesis in cardiovascular research. This book provides step-by-step methods for the successful completion of experimental procedures, and would be useful for both experienced and new investigators in the field of molecular cardiology.
Author: Marie Irene Ferrer
Publisher: Wiley-Blackwell
ISBN:
Category : Medical
Languages : en
Pages : 144
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Book Description
Author: Victor J. Dzau, MD
Publisher: John Wiley & Sons
ISBN: 0470765941
Category : Medical
Languages : en
Pages : 328
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Book Description
Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand: • how cardiovascular genetics may remodel the way cardiovascular medicine is practiced • what material has immediate relevance to the practicing clinician • how to incorporate genetics and genomics in your practice to ensure up-to-date patient care The book opens with introductory chapters, then discusses: • cardiovascular single gene disorders • cardiovascular polygenic disorders • therapies and applications Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.
Author: Ambrose S. Kibos
Publisher: Springer Science & Business Media
ISBN: 1447153162
Category : Medical
Languages : en
Pages : 678
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Book Description
This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.
Author: Zainul Abedin
Publisher: John Wiley & Sons
ISBN: 1118522028
Category : Medical
Languages : en
Pages : 497
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Book Description
This new edition of Essential Cardiac Electrophysiology: The Self-Assessment Approach continues the successful formula of the first edition, providing a concise and thorough overview of Electrophysiology supplemented by challenging questions readers can use to test their knowledge and prepare for examinations. Comprehensively updated and significantly expanded to include the latest recommendations, findings from leading-edge research, emergent diagnostic tools, and new therapeutic options, Essential Cardiac Electrophysiology: The Self-Assessment Approach now offers coverage of some of hottest topics in EP, including: HCN channels; Congenital, and paroxysmal AV blocks; Left atrial flutter; Electrophysiologic assessment of AVNRT and AVRT; VT ablation; Short QT syndrome; Early repolarization and ventricular fibrillation; Aortic cusp VT; Commotio Cordis, and more. Fact-based and clinically-focused, Essential Cardiac Electrophysiology: The Self-Assessment Approach is an ideal reference for all members of the EP care team, from cardiac care nurses and technicians to EP and cardiology fellows to practicing electrophysiologists. Packed with questions designed to aid readers’ understanding of key concepts and retention of essential facts, it is an excellent study aid for those preparing for board examination or other EP certifications.
Author: Masaki Ieda
Publisher: Springer
ISBN: 3319561065
Category : Medical
Languages : en
Pages : 274
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Book Description
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Author: Fernando Vivanco
Publisher: Springer Science & Business Media
ISBN: 1597452149
Category : Science
Languages : en
Pages : 412
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Book Description
This cutting-edge book presents protocols and strategies for proteomic evaluation of cardiovascular disease written by pioneering researchers in the field. Topics explored in this comprehensive volume include obtaining specific heart proteins, techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels.
