Chromatin Immunoprecipitation Assays

Chromatin Immunoprecipitation Assays PDF Author: Philippe Collas
Publisher: Methods in Molecular Biology
ISBN:
Category : Computers
Languages : en
Pages : 290

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Book Description
In this book, researchers deeply involved in the development and improvement of chromatin immunoprecipitation assays (ChIP) provide cutting-edge protocols devoted to the most recent progress in ChIP and related subjects.

Capturing Chromosome Conformation

Capturing Chromosome Conformation PDF Author: Beatrice Bodega
Publisher: Humana
ISBN: 9781071606636
Category : Science
Languages : en
Pages : 322

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Book Description
This detailed book collects methods based on the evolution of the chromosome conformation capture (3C) technique and other complementary approaches to dissect chromatin conformation with an emphasis on dissection of nuclear compartmentalization and visualization in imaging. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Capturing Chromosome Conformation: Methods and Protocols serves as an ideal guide for researchers working to further understand 3D genome organization.

Chromatin Immunoprecipitation Assays

Chromatin Immunoprecipitation Assays PDF Author: Philippe Collas
Publisher: Methods in Molecular Biology
ISBN:
Category : Computers
Languages : en
Pages : 290

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Book Description
In this book, researchers deeply involved in the development and improvement of chromatin immunoprecipitation assays (ChIP) provide cutting-edge protocols devoted to the most recent progress in ChIP and related subjects.

Hi-C Data Analysis

Hi-C Data Analysis PDF Author: Silvio Bicciato
Publisher: Humana
ISBN: 9781071613924
Category : Science
Languages : en
Pages : 0

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Book Description
This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Hi-C Data Analysis: Methods and Protocols aims to help computational and molecular biologists working in the field of chromatin 3D architecture and transcription regulation.

Plant Genomics

Plant Genomics PDF Author: Wolfgang Busch
Publisher: Humana Press
ISBN: 9781493983643
Category : Science
Languages : en
Pages : 317

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Book Description
This volume provides protocols that revolve around three pillars of progress in the plant genomics field: genotypes, phenotypes, and the molecular processes in between. Chapters in Plant Genomics: Methods and Protocols are not restricted to the predominant model species Arabidopsis thaliana, hoping to encourage and facilitate other researchers to expand their research to other species. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Plant Genomics: Methods and Protocols aims to serve as an inspiration for further studies in plant genomics.

Plant Chromatin Dynamics

Plant Chromatin Dynamics PDF Author: Marian Bemer
Publisher: Humana
ISBN: 9781493984510
Category : Science
Languages : en
Pages : 0

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Book Description
This volume provides a comprehensive collection of protocols that can be used to study plant chromatin structure and composition. Chapters divided into three sections detail the profiling of chromatin features in relation to epigenetic regulation, investigate the interaction between chromatin modifications and gene regulation, and explore the 3D spatial organization of the chromatin inside the nucleus. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Plant Chromatin Dynamics: Methods and Protocols aims to ensure successful results in the further study of this vital field.

HiC-Pro: an Optimized and Flexible Pipeline for Hi-C Data Processing

HiC-Pro: an Optimized and Flexible Pipeline for Hi-C Data Processing PDF Author: Oldenburg Oldenburg Press
Publisher:
ISBN: 9781523764426
Category :
Languages : en
Pages : 40

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Book Description
HiC-Pro is an optimized and flexible pipeline for processing Hi-C data from raw reads to normalized contact maps. HiC-Pro maps reads, detects valid ligation products, performs quality controls and generates intra- and inter-chromosomal contact maps. It includes a fast implementation of the iterative correction method and is based on a memory-efficient data format for Hi-C contact maps. In addition, HiC-Pro can use phased genotype data to build allele-specific contact maps. We applied HiC-Pro to different Hi-C datasets, demonstrating its ability to easily process large data in a reasonable time. Source code and documentation are available at http://github.com/nservant/HiC-Pro.

Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation

Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation PDF Author: Narendra Wajapeyee
Publisher:
ISBN: 9781493965182
Category : Biomedicine
Languages : en
Pages : 278

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Book Description
This volume describes a variety of protocols that will allow the readers to study different aspects of transcriptional and posttranscriptional gene expression regulation in eukaryotic cells. Chapters focus on the latest use of CRISPRi and RNAi technologies for studying various aspects of transcriptional and posttranscriptional regulation and tools to navigate protocols on key bioinformatics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls Authoritative and cutting-edge, Eukaryotic Transcription and Post-Transcription Gene Expression Regulation aims to ensure successful results in the further study of this vital field.

Parasite Genomics

Parasite Genomics PDF Author: Luis M. de Pablos
Publisher: Humana
ISBN: 9781071616802
Category : Medical
Languages : en
Pages : 336

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Book Description
This detailed book provides a comprehensive series of innovative research techniques and methodologies applied to the parasite genomics research area, all applying different approaches to analyzing parasite genomes and furthering the study of genetic complexity and the mechanisms of regulation. Beginning with chapters on novel sequencing and the bioinformatics pipeline, the volume continues by exploring diagnostic approaches using genomic tools, host-parasite interactions, as well as the genomics of parasite-derived extracellular vesicles. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Parasite Genomics: Methods and Protocols creates a detailed picture of genomic approaches for researchers seeking a better understanding of characterizing parasite nucleic acid content.

Epigenetics and Systems Biology

Epigenetics and Systems Biology PDF Author: Leonie Ringrose
Publisher: Academic Press
ISBN: 0128030763
Category : Science
Languages : en
Pages : 287

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Book Description
Epigenetics and Systems Biology highlights the need for collaboration between experiments and theoretical modeling that is required for successful application of systems biology in epigenetics studies. This book breaks down the obstacles which exist between systems biology and epigenetics researchers due to information barriers and segmented research, giving real-life examples of successful combinations of systems biology and epigenetics experiments. Each section covers one type of modeling and one set of epigenetic questions on which said models have been successfully applied. In addition, the book highlights how modeling and systems biology relate to studies of RNA, DNA, and genome instability, mechanisms of DNA damage signaling and repair, and the effect of the environment on genome stability. - Presents original research in a wider perspective to reveal potential for synergies between the two fields of study - Provides the latest experiments in primary literature for the modeling audience - Includes chapters written by experts in systems biology and epigenetics who have vast experience studying clinical applications

Kew Chromosome Conference IV

Kew Chromosome Conference IV PDF Author: P. E. Brandham
Publisher: Balogh Scientific Books
ISBN:
Category : Science
Languages : en
Pages : 494

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Book Description
Papers from 36 speakers covering chromosomes, populations and conservation, chromosomes and economic botany, genome organisation, cytotaxonomy and evolution, chromosome structure and activity, and chromosomes in reproduction and development.