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Author:
Publisher:
ISBN:
Category : Lawyers
Languages : en
Pages : 1514
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Book Description
Author:
Publisher:
ISBN:
Category : Lawyers
Languages : en
Pages : 1514
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Book Description
Author: Michael R. Kreutz
Publisher: Springer Science & Business Media
ISBN: 3709109310
Category : Medical
Languages : en
Pages : 611
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Book Description
This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.
Author: James F. Zachary
Publisher: Elsevier Health Sciences
ISBN: 0323075339
Category : Medical
Languages : en
Pages : 1339
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Book Description
With over 2,000 full-color illustrations, Pathologic Basis of Veterinary Disease, 5th Edition provides complete coverage of both general pathology and pathology of organ systems in one convenient resource. In-depth explanations cover the responses of cells, tissues, and organs to injury and infection. Expert researchers James F. Zachary and M. Donald McGavin keep you up to date with the latest advances in cellular and molecular pathology plus expanded coverage of genetics and disease, incorporating the newest insights into the study of disease mechanisms, genesis, and progression. Already the leading reference for pathology, this edition also includes an enhanced website with images of less common diseases and and guidelines for performing a complete, systematic necropsy. Each chapter is consistently organized, presenting information on structure, function, portals of entry, defense mechanisms, responses to injury, and diseases organized by species.Full-color illustrations, schematics, flow charts, and diagrammatic representations of disease processes make it easier to understand difficult concepts.Discussions of pathologic processes and individual disorders are integrated with the latest established information available.Clear, up-to-date explanations of disease mechanisms describe the cell, tissue, and organ response to injury and infection.Over 20 recognized experts deliver the most relevant information, whether you're a practitioner, student, or preparing for the American College of Veterinary Pathology board examination. Updated content on cellular and organ system pathology provides the latest on the science of inflammation, cellular injury, molecular carcinogenesis, and pathogenesis.NEW topics include the genetic basis of disease, the monocyte-macrophage system, diseases of the ear, and disorders of ligaments and joints and of the peritoneum.NEW coverage of World Organization for Animal Health (OIE) reportable diseases ("foreign animal diseases") adds information on microorganisms that have catastrophic impact on livestock health and production.NEW Mechanisms of Microbial Infections chapter adds in-depth coverage of the means by which microbes encounter, colonize, and cause disease in animals in a chronological sequence of events.NEW and updated flow charts, schematic illustrations, and diagrams of disease processes summarize important information and clarify complex concepts. An enhanced companion website includes all the images from the book, plus additional images and schematic illustrations of common diseases; guidelines for performing a complete, systematic necropsy and appropriate sample acquisition for selected organ systems; and a glossary of terms to accompany selected organ systems.
Author: Ralph A. Bradshaw
Publisher: Academic Press
ISBN: 0080920918
Category : Science
Languages : en
Pages : 3188
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Book Description
Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field
Author: James F. Zachary
Publisher: Elsevier Health Sciences
ISBN: 0323291724
Category : Medical
Languages : en
Pages : 1339
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Book Description
Pathologic Basis of Veterinary Disease - E-Book
Author: Alan D. Michelson
Publisher: Elsevier
ISBN: 0080465862
Category : Medical
Languages : en
Pages : 1386
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Book Description
Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. - First edition won Best Book in Medical Science Award from the Association of American Publishers - Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias - A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references
Author:
Publisher:
ISBN:
Category : Law
Languages : en
Pages : 2072
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Book Description
Author: Edward A. Dennis
Publisher: Academic Press
ISBN: 0123838622
Category : Science
Languages : en
Pages : 604
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Book Description
"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
Author: Isabella Savini
Publisher: MDPI
ISBN: 3039366904
Category : Medical
Languages : en
Pages : 240
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Book Description
The present book, which includes eleven articles five reviews and six original studies published in the Special Issue “Molecular Research On Platelet Activity in Health and Disease”, gives an international picture of the up-to-date understanding of (i) platelet signaling under physiological and pathological conditions; (ii) novel technologies for monitoring platelet functions; and (iii) clinical applications of platelet-based-therapy for management of pathological conditions, not directly related to hemostasis and thrombosis. The book reveals novel aspects of platelet biology, and will be helpful for offering new insights and a research impetus for those who are interested in developing new therapeutic tools for the management of pathological conditions depending on platelet dysfunctions.
Author: Alexander G. Karczmar
Publisher: Springer Science & Business Media
ISBN: 038746526X
Category : Science
Languages : en
Pages : 698
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Book Description
Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.
