Author: Georg Dietz
Publisher:
ISBN: 9783924943073
Category :
Languages : en
Pages : 162

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Book Description

Author: Kim Freeman
Publisher:
ISBN:
Category :
Languages : en
Pages : 78

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Author: Govind Balkrishna Shankwalker
Publisher:
ISBN:
Category :
Languages : en
Pages : 188

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Book Description

Author: Jona J. Sela
Publisher: Springer Science & Business Media
ISBN: 146142058X
Category : Technology & Engineering
Languages : en
Pages : 161

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Book Description
Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying conditions. Bone healing is affected by a multitude of genetic, environmental, mechanical, cellular and endocrine variables which eventually lead to changes in gene expression that enhance the guided action of osteoblasts (and chondroblasts) to lay down bone that restores, or even improves, the skeletal load bearing capacity. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones.

Author: Jay R. Lieberman
Publisher: Springer Science & Business Media
ISBN: 0896038475
Category : Medical
Languages : en
Pages : 400

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Book Description
This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.

Author: Annelie Lengheden
Publisher:
ISBN:
Category : Calcium hydroxide
Languages : en
Pages : 158

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Author: Haim Tal
Publisher: BoD – Books on Demand
ISBN: 953510487X
Category : Technology & Engineering
Languages : en
Pages : 364

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Book Description
Bone is a specialized connective tissue, most prominently characterized by its mineralized organic matrix that imparts the physical properties that allow bone tissue to resist load, to support functional organs, and to protect highly sensitive body parts. Bone loss and bone damage may occur as a result of genetic conditions, infectious diseases, tumours, and trauma. Bone healing and repair, involves integrative activity of native tissues and living cells, and lends itself to the incorporation of naturally derived or biocompatible synthetic scaffolds, aimed at replacing missing or damaged osseous tissues. There are several modalities of bone regeneration including tissue engineering, guided bone regeneration, distraction ontogenesis, and bone grafting. This book concentrates on such procedures that may well be counted among the recent outstanding breakthroughs in bone regenerative therapy.

Author: Jens O. Andreasen
Publisher: John Wiley & Sons
ISBN: 111916706X
Category : Medical
Languages : en
Pages : 1063

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Book Description
Textbook and Color Atlas of Traumatic Injuries to the Teeth, Fifth Edition encompasses the full scope of acute dental trauma, including all aspects of interdisciplinary treatment. This new edition embraces the significant advances made in the subject of dental traumatology since the publication of the previous edition in 2007. Thoroughly updated throughout, it includes eight new chapters, including one chapter focused on the development of bioengineered teeth and another on clinical regenerative endodontics. Providing the theoretical background behind the clinical applications, the text is supplemented by a step-by-step online guide to procedures at www.dentaltraumaguide.org. The book is also filled with full-color illustrations throughout—making it the ultimate guide for anyone treating individuals afflicted with dental injuries caused by traffic accidents, sporting injuries, violent assaults, and other falls, crashes, or injuries. New edition of the definitive reference on dental traumatology Thoroughly revised and updated with a modern look and feel Eight new chapters on innovative developments in the field Contributions from world-renowned authors and editors Linked to www.dentaltraumaguide.org with a specific chapter on how the book complements the online guide This comprehensive textbook is an invaluable reference for undergraduate BDS courses worldwide, as well as a core text for postgraduate pediatric, oral surgery, and endodontics courses.

Author: Ki-tae Koo
Publisher:
ISBN:
Category : Bone regeneration
Languages : en
Pages : 60

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Book Description

Author: Daniel O. Costa
Publisher:
ISBN:
Category :
Languages : en
Pages : 458

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Book Description
Bone defects are a prevalent problem in orthopedics and dentistry. Calcium phosphate-based coatings and nanocomposites offer unique solutions towards producing scaffolds with suitable physical, mechanical and biological properties for bone regeneration. We developed a novel method to synthesize hydroxyapatite (HA) particles with high aspect ratio using sol-gel chemistry and hydrothermal treatment. We obtained tunable pure-phase carbonated-HA in the form of micro/nanorods and nanowires (diameters 25-800 nm). To mimic the structure of bone, HA nanowires were homogenously mixed within poly( -caprolactone) (PCL) to produce nanocomposites with improved mechanical properties as determined by uniaxial tensile testing. Surface chemistry and topography of biomaterials play prominent roles in regulating cell adhesion and differentiation. Bone-like apatite coatings, produced by incubating materials in a simulated body fluid (SBF), improve the osteoconductivity of scaffold materials. However, few studies have controlled the surface topography of biomimetic HA. We assessed the effect of SBF ion concentration and soaking time on the surface properties of apatite coatings. Calcium phosphates such as carbonated-HA with similar chemical composition and stiffness were deposited onto PCL films. Characterization of these coatings revealed an increase in topographical complexity and surface roughness with increasing ion concentration of SBF and soaking time. To investigate their potential application in bone regeneration, we studied the influence of topography of biomimetic HA coatings on the behavior of osteoblasts and osteoclasts in vitro. Osteoblast attachment and differentiation were significantly greater iv when cultured on rougher HA surfaces (Ra 2̃ m) than on smoother topographies (Ra 1̃ m). In contrast, activity of tartrate-resistant acid phosphatase (an osteoclast marker) was greater on smoother than on rougher HA surfaces. Furthermore, osteoclastic resorption lacunae were found exclusively on smoother HA coatings. Inhibition of resorption on rougher HA surfaces was associated with disruption of filamentous actin sealing zones. In conclusion, HA coatings can be prepared with different topographies, which regulate responses of osteoblasts and osteoclasts. Thus, it may be possible to design HA-polymer composites and HA-coated polymers with physical, mechanical and biological properties suitable for tissue engineering. By modulating topography, rates of bone formation and biodegradation could be tailored for specific applications in orthopedics and dentistry.