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Author: Gianluca Tadini
Publisher: Springer Nature
ISBN: 3319924508
Category : Medical
Languages : en
Pages : 316
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Book Description
This volume offers an update of the clinical signs, diagnostic criteria (including molecular diagnosis) and targeted therapies for a particular type of genodermatosis, providing a handy and unique tool for early diagnosis. In recent years, our understanding of genodermatosis and neurocutaneous syndromes has increased, but although Type 1 Neurofibromatosis (NF1) is the most common neuroectodermal disorder and involves a large number of patients and medical disciplines, this syndrome remains underestimated, often misdiagnosed thus leading to inaccurate treatment. The literature on the molecular and pathogenetic aspects is ample, but current clinical approaches, classification, diagnostic criteria and treatment protocols are outdated, creating difficulties in early diagnosis and treatment. As such, a chapter is devoted renewing current diagnostic criteria; it includes clinical and molecular data, to offer a sound, updated discussion basis for a consensus conference. NF1 is a “time-dependent” disorder, meaning that the onset of clinical signs are closely linked to patient age and the book discusses this particularly neglected aspect extensively, as well as the latest molecular diagnosis techniques, which are highly sensitive have not been included in the diagnostic criteria. It also explains the role of the RAS-MAPK pathway and genotype-phenotype correlations. In addition it explores new concepts concerning the pathogenesis of neurofibromas and other hamarthomas and their relevance for a modern therapeutical approach with targeted molecular drugs, as well as newly discovered aspects of NF1 in all internal organs, together with their diagnostic counterparts. A chapter on mosaic neurofibromatosis is also included. There is a particular focus on differential diagnosis (i.e. other diseases with café-au-lait macules), and the recently described Legius syndrome will be presented directly by Prof Eric Legius. All chapters are easy-to-understand, up-to-date, comprehensive and concise tools and are intended for a wide range of professionals involved with genetic disorders of the skin and neurocutaneous diseases: dermatologists, pediatricians, neurologists, oncologists and general practitioners.
Author: Gianluca Tadini
Publisher: Springer Nature
ISBN: 3319924508
Category : Medical
Languages : en
Pages : 316
Get Book Here
Book Description
This volume offers an update of the clinical signs, diagnostic criteria (including molecular diagnosis) and targeted therapies for a particular type of genodermatosis, providing a handy and unique tool for early diagnosis. In recent years, our understanding of genodermatosis and neurocutaneous syndromes has increased, but although Type 1 Neurofibromatosis (NF1) is the most common neuroectodermal disorder and involves a large number of patients and medical disciplines, this syndrome remains underestimated, often misdiagnosed thus leading to inaccurate treatment. The literature on the molecular and pathogenetic aspects is ample, but current clinical approaches, classification, diagnostic criteria and treatment protocols are outdated, creating difficulties in early diagnosis and treatment. As such, a chapter is devoted renewing current diagnostic criteria; it includes clinical and molecular data, to offer a sound, updated discussion basis for a consensus conference. NF1 is a “time-dependent” disorder, meaning that the onset of clinical signs are closely linked to patient age and the book discusses this particularly neglected aspect extensively, as well as the latest molecular diagnosis techniques, which are highly sensitive have not been included in the diagnostic criteria. It also explains the role of the RAS-MAPK pathway and genotype-phenotype correlations. In addition it explores new concepts concerning the pathogenesis of neurofibromas and other hamarthomas and their relevance for a modern therapeutical approach with targeted molecular drugs, as well as newly discovered aspects of NF1 in all internal organs, together with their diagnostic counterparts. A chapter on mosaic neurofibromatosis is also included. There is a particular focus on differential diagnosis (i.e. other diseases with café-au-lait macules), and the recently described Legius syndrome will be presented directly by Prof Eric Legius. All chapters are easy-to-understand, up-to-date, comprehensive and concise tools and are intended for a wide range of professionals involved with genetic disorders of the skin and neurocutaneous diseases: dermatologists, pediatricians, neurologists, oncologists and general practitioners.
Author: Erin Benzakein
Publisher: Chronicle Books
ISBN: 1452181853
Category : Gardening
Languages : en
Pages : 229
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Book Description
A stunning guide to growing, harvesting, and arranging gorgeous dahlia blooms from celebrated farmer-florist and New York Times bestselling author Erin Benzakein, founder of Floret Flower Farm. World-renowned flower farmer and floral designer Erin Benzakein reveals all the secrets to growing, cultivating, and arranging gorgeous dahlias. These coveted floral treasures come in a dazzling range of colors, sizes, and forms, with enough variety for virtually every garden space and personal preference, making them one of the most beloved flowers for arrangements. In these pages, readers will discover: • Expert advice for planting, harvesting, and arranging garden-fresh dahlias • A simple-to-follow overview of the dahlia classification system • An A–Z guide with photos and descriptions of more than 350 varieties • Step-by-step how-to's for designing show-stopping dahlia bouquets that elevate any occasion Expert Author: Erin Benzakein's gorgeous flowers are celebrated throughout the world. Her book Floret Farm's A Year in Flowers was a New York Times bestseller and her first book, Floret Farm's Cut Flower Garden, won the American Horticultural Society Book Award. Filled with Wisdom: Overflowing with hundreds of lush photographs and invaluable advice, DISCOVERING DAHLIAS is an essential resource for gardeners and a must-have for anyone who loves flowers, including flower lovers, avid and novice gardeners, floral designers, florists, small farmers, stylists, and designers.
Author: David Lebovitz
Publisher: Ten Speed Press
ISBN: 1607749297
Category : Cooking
Languages : en
Pages : 306
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Book Description
TALES OF THE COCKTAIL SPIRITED AWARD® WINNER • IACP AWARD FINALIST • The New York Times bestselling author of My Paris Kitchen serves up more than 160 recipes for trendy cocktails, quintessential apéritifs, café favorites, complementary snacks, and more. Bestselling cookbook author, memoirist, and popular blogger David Lebovitz delves into the drinking culture of France in Drinking French. This beautifully photographed collection features 160 recipes for everything from coffee, hot chocolate, and tea to Kir and regional apéritifs, classic and modern cocktails from the hottest Paris bars, and creative infusions using fresh fruit and French liqueurs. And because the French can't imagine drinking without having something to eat alongside, David includes crispy, salty snacks to serve with your concoctions. Each recipe is accompanied by David's witty and informative stories about the ins and outs of life in France, as well as photographs taken on location in Paris and beyond. Whether you have a trip to France booked and want to know what and where to drink, or just want to infuse your next get-together with a little French flair, this rich and revealing guide will make you the toast of the town.
Author: Jane Eastoe
Publisher: Gibbs Smith
ISBN: 1423646711
Category : Gardening
Languages : en
Pages : 0
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Book Description
"Vintage roses encompass both the true 'old' roses and the best of the 'modern' roses, developed to celebrate the classic, ageless, enduring beauty of the old varieties. The 60 specially selected specimens include those that have the best visual appearance and most fragrant perfume, and are also easy to grow and produce beautiful flowers for cutting"--Amazon.com.
Author: Doris Longacre
Publisher: MennoMedia, Inc.
ISBN: 083619781X
Category : Cooking
Languages : en
Pages : 492
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Book Description
This is a new edition of Herald Press's all-time best-selling cookbook, helping thousands of families establish a climate of joy and concern for others at mealtime. The late author's introductory chapters have been edited and revised for today's cooks. Statistics and nutritional information have been updated to reflect current American and Canadian eating habits, health issues, and diet guidelines. The new U.S. food chart "My Plate" was slipped in at the last minute and placed alongside Canada's Food Guide. But the message has changed little from the one that Doris Janzen Longacre promoted in 1976, when the first edition of this cookbook was released. In many ways she was ahead of her time in advocating for people to eat more whole grains and more vegetables and fruits, with less meat, saturated fat, and sugars. This book is part of the World Community Cookbook series that is published in cooperation with Mennonite Central Committee, a worldwide ministry of relief, development, and peace. "Mennonites are widely recognized as good cooks. But Mennonites are also a people who care about the world’s hungry."—Doris Janzen Longacre
Author: Dr. H. K. Saboowala.
Publisher: Dr.Hakim Saboowala
ISBN:
Category : Medical
Languages : en
Pages : 45
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Book Description
A Brief Summary of “Café-au-lait Macules (CALM)” and “Neurofibromatosis Type1.” Cafe-au-lait macules (CALMs) are common pigmented lesions found in the general population. They can be described as well-circumscribed, pigmented macules or patches ranging from light to dark brown. Their size may range from a few millimeters to several centimetres (>20cm) and may appear at birth or early life. Multiple CALMs are often associated with genetic syndromes for which the patient and family members need to be evaluated by an interprofessional team. CALMs are mostly benign and are treated with laser therapy for cosmetic purposes. It is strived in this E-Booklet to discuss the Aetiology, Diagnosis, Outlook, Evaluation and Treatment of cafe-au-lait macules along with relevant cited Images for better understanding. Dr. H. K. Saboowala. M.B.,B.S.(Bom) F.S.A.M.S (Derm) F.S.I.C.D.
Author: Jessica M. Boehman
Publisher: Roadrunner Press
ISBN: 9781937054786
Category : FICTION
Languages : en
Pages : 0
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Book Description
"By day, the library lions Patience and Fortitude guard the iconic New York Public Library. But when the sun goes down, and the library closes, their work is done, and it is time for fun. This debut wordless picture book brings the reader along on a late-night subway trip to the wild and wonderful Coney Island, where the two lions fit right in and indulge in some classic New York City-style fun. Will they make it back to the library before dawn? And will anyone notice that they've been gone?" -- Amazon.
Author: Torello Lotti
Publisher: Springer Nature
ISBN: 3030508234
Category : Medical
Languages : en
Pages : 198
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Book Description
This book provides a guide to the diagnosis and management of pigmentary disorders. Each chapter explores a different clinical case to give the reader an interdisciplinary understanding of treatment options. Particular attention is given to the treatment of hypopigmentation, hypomelanosis and discoloration with cases highlighting the effects of drug intake, genetic alterations and the polluted environment. Clinical Cases in Pigmentary Disorders examines therapeutic approaches through evidence-based best practice techniques and is relevant to dermatologists, oncologists, pharmacologists and pathologists.
Author: Amanda Oakley
Publisher: Scion Publishing Ltd
ISBN: 1911510118
Category : Medical
Languages : en
Pages : 438
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Book Description
A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.
Author: Helen S. Fletcher
Publisher: Helen S. Fletcher
ISBN:
Category : Cooking
Languages : en
Pages : 358
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Book Description
Helen S. Fletcher has been making pastry dreams come true for over 45 years! As a renowned pastry chef, Helen owned a commercial bakery that provided high-end pastries, cakes and delicacies to fine restaurants and venues for more than thirty years. She has previously authored The New Pastry Cook and European Tarts, sharing her vast knowledge and recipes. Helen has always loved teaching people of all ages and abilities. She has taught her specialized craft at the collegiate level, as a regular on various cooking shows, as a consultant to Cuisinart, as a writer for Bon Appetit Magazine, and as a role model to other pastry chefs. Helen always keeps the baker in mind with clear, detailed and down-to-earth instructions. Pictures of each of the cookies enhance the book and give readers a visual goal for their efforts. Where words alone do not clearly convey the instructions, additional photos are included as a guide. Craving Cookies is a labor of love and her personal journey through the creation of American cookies. Helen invites you into her kitchen as she shares new and classic recipes and techniques gathered from her years baking experience.
