Molecular Therapies of Cancer PDF Download
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Author: Georg F. Weber
Publisher: Springer
ISBN: 3319132784
Category : Medical
Languages : en
Pages : 486
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Book Description
Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.
Author: Georg F. Weber
Publisher: Springer
ISBN: 3319132784
Category : Medical
Languages : en
Pages : 486
Get Book Here
Book Description
Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.
Author: Huadong Guo
Publisher: Springer Nature
ISBN: 9813299150
Category : Technology & Engineering
Languages : en
Pages : 846
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Book Description
This open access book offers a summary of the development of Digital Earth over the past twenty years. By reviewing the initial vision of Digital Earth, the evolution of that vision, the relevant key technologies, and the role of Digital Earth in helping people respond to global challenges, this publication reveals how and why Digital Earth is becoming vital for acquiring, processing, analysing and mining the rapidly growing volume of global data sets about the Earth. The main aspects of Digital Earth covered here include: Digital Earth platforms, remote sensing and navigation satellites, processing and visualizing geospatial information, geospatial information infrastructures, big data and cloud computing, transformation and zooming, artificial intelligence, Internet of Things, and social media. Moreover, the book covers in detail the multi-layered/multi-faceted roles of Digital Earth in response to sustainable development goals, climate changes, and mitigating disasters, the applications of Digital Earth (such as digital city and digital heritage), the citizen science in support of Digital Earth, the economic value of Digital Earth, and so on. This book also reviews the regional and national development of Digital Earth around the world, and discusses the role and effect of education and ethics. Lastly, it concludes with a summary of the challenges and forecasts the future trends of Digital Earth. By sharing case studies and a broad range of general and scientific insights into the science and technology of Digital Earth, this book offers an essential introduction for an ever-growing international audience.
Author: Mieczyslaw A. Klopotek
Publisher: Springer Science & Business Media
ISBN: 3540323929
Category : Computers
Languages : en
Pages : 678
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Book Description
The international conference Intelligent Information Processing and Web Mining IIS:IIPWM’05, organized in Gda?sk-Sobieszewo on 13–16th June, 2005, was a continuation of a long tradition of conferences on applications of Arti?cial Intelligence (AI) in Information Systems (IS), organized by the Institute of Computer Science of Polish Academy of Sciences in cooperation with other scienti?c and business institutions. The Institute itself is deeply engaged in research both in AI and IS and many scientists view it as a leading institution both in fundamental and - plied research in these areas in Poland. The originators of this conference series, Prof. M. D?browski and Dr. M. Michalewicz had in 1992 a long-term goal of bringing together scientists and industry of di?erent braches from Poland and abroad to achieve a creative synthesis. One can say that their dream has come to reality. Scientists from ?ve continents made their subm- sions to this conference. A brief look at the a?liations makes international cooperation visible. The research papers have either a motivation in c- crete applications or are o?-springs of some practical requests. This volume presents the best papers carefully chosen from a large set of submissions (about 45%). At this point we would like to express our thanks to the m- bers of Programme Committee for their excellent job. Also we are thankful to the organizers of the special sessions accompanying this conference: Jan Komorowski, Adam Przepiórkowski, Zbigniew W.
Author: Thomas Owens
Publisher: Oxford University Press
ISBN: 0195355539
Category : Music
Languages : en
Pages : 339
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Book Description
"When bebop was new," writes Thomas Owens, "many jazz musicians and most of the jazz audience heard it as radical, chaotic, bewildering music." For a nation swinging to the smoothly orchestrated sounds of the big bands, this revolutionary movement of the 1940s must have seemed destined for a short life on the musical fringe. But today, Owens writes, bebop is nothing less than "the lingua franca of jazz, serving as the principal musical language of thousands of jazz musicians." In Bebop, Owens conducts us on an insightful, loving tour through the music, players, and recordings that changed American culture. Combining vivid portraits of bebop's gigantic personalities with deft musical analysis, he ranges from the early classics of modern jazz (starting with the 1943 Onyx Club performances of Dizzy Gillespie, Max Roach, Oscar Pettiford, Don Byas, and George Wallington) through the central role of Charlie Parker, to an instrument-by-instrument look at the key players and their innovations. Illustrating his discussion with numerous musical excerpts, Owens skillfully demonstrates why bebop was so revolutionary, with fascinating glimpses of the tempestuous jazz world: Thelonious Monk, for example, did "everything 'wrong' in the sense of traditional piano technique....Because his right elbow fanned outward away from his body, he often hit the keys at an angle rather than in parallel. Sometimes he hit a single key with more than one finger, and divided single-line melodies between two hands." In addition to his discussions of individual instruments and players, Owens examines ensembles, with their sometimes volatile collaborations: in the Jazz Messengers, Benny Golson told of how his own mellow saxophone playing would get lost under Art Blakey's furious drumming: "He would do one of those famous four-bar drum rolls going into the next chorus, and I would completely disappear. He would holler over at me, 'Get up out of that hole!'" In this marvelous account, Owens comes right to the present day, with accounts of new musicians ranging from the Marsalis brothers to lesser-known masters like pianist Michel Petrucciani. Bebop is a jazz-lover's dream--a serious yet highly personal look at America's most distinctive music.
Author: John Beech
Publisher: Pearson Higher Ed
ISBN: 0273758640
Category : Business & Economics
Languages : en
Pages : 418
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Book Description
Events Management 1e John Beech, Sebastian Kaiser and Robert Kaspar The Business of Events Management provides an accessible and lively introduction to the practice of managing an event, festival, conference or congress. Written by a team of international experts, the book incorporates the latest thinking in events management and highlights key theories, concepts and models by using a range of case studies and examples. This book will enable you to: Manage the financial aspects of events management Understand the impact of events on built and natural environments Explain the role of volunteers in an event and understand the challenges that managing them involves Understand the key issues in planning and designing a venue Each chapter features a real-life case study to illustrate key concepts and place theory in a practical context, as well as preparing students to tackle any challenges they may face in managing events. Case studies include the Edinburgh International Festival, the 2010 Winter Olympics and Indian Premier League Cricket.
Author: Joan Cutting
Publisher: Routledge
ISBN: 1134525257
Category : Language Arts & Disciplines
Languages : en
Pages : 200
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Book Description
Pragmatics and Discourse, 2nd edition: has been revised and reorganised to place more emphasis on pragmatics covers the core areas of the subject: context and co-text, Speech Act Theory, Conversation Analysis, Exchange Structure, Interactional Sociolinguistics, the Cooperative Principle, Politeness Theory and extends to more applied areas: Corpus Linguistics & Communities of Practice, and Intercultural Pragmatics, Interlanguage Pragmatics & language learning draws on a wealth of texts: from Bend it Like Beckham and The Motorcycle Diaries to political speeches, newspaper extracts and blogs. provides classic readings from the key names in the discipline, from Sperber and Wilson to Fairclough, Wodak and Gumperz is accompanied by a supporting website Key features of the new edition include: two new strands on Corpora & Communities and Culture & Language Learning; the merging of two strands on Context and Co-text; new material from speaker-based cognitive linguistics; updated references; and fresh examples and exercises. Written by an experienced teacher and author, this accessible textbook is an essential resource for all students of English language and linguistics.
Author: Roger G. Harrison
Publisher: Oxford University Press
ISBN: 0190213736
Category : Technology & Engineering
Languages : en
Pages : 577
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Book Description
Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.
Author: John Stark
Publisher: Springer
ISBN: 303016134X
Category : Technology & Engineering
Languages : en
Pages : 282
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Book Description
This book presents some twenty case studies, showing how companies in different industry sectors and of different sizes make advances in Product Lifecycle Management (PLM). Like the author’s previous volumes, this book provides a valuable resource for those wishing to learn about PLM and how to implement and apply it in their companies. Helping readers to · learn about implementing and benefiting from PLM; · learn about good PLM solutions and best practice; · improve their planning and decision-making abilities; · benefit from the lessons learned by the companies featured in the case studies; · proceed faster and further with PLM the book presents effective PLM solutions and best practices. At the same time, the case studies included demonstrate how different companies implement and benefit from PLM. Each case study is addressed in a separate chapter and details a different situation, enabling readers to put themselves in the situation and think through different actions and decisions. A valuable resource for PLM team managers and employees in engineering and manufacturing companies, the book is also of interest to researchers and students in industrial engineering fields.
Author: S. Gilman
Publisher: Springer
ISBN: 1403973601
Category : Religion
Languages : en
Pages : 247
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Book Description
In this collection of new essays, Sander Gilman muses on Jewish memory and representation throughout the twentieth-century. Bringing together the worlds of literature, medicine, and popular culture in his characteristic ways, Gilman looks at new, post-diasporic ways of understanding the limits of Jewish identity. Topics include the development of the genre of Holocaust comedy, the imagination of the relationship of the body, disease, and identity, and the place of Jews in today's multicultural society.
Author: Patrick K. Schmidt
Publisher: Oxford University Press
ISBN: 0190246146
Category : Education
Languages : en
Pages : 297
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Book Description
Policy and the Political Life of Music Education is the first book of its kind in the field of Music Education. It offers a far-reaching and innovative outlook, bringing together expert voices who provide a multifaceted and global set of insights into a critical arena for action today: policy. On one hand, the book helps the novice to make sense of what policy is, how it functions, and how it is discussed in various parts of the world; while on the other, it offers the experienced educator a set of critically written analyses that outline the state of the play of music education policy thinking. As policy participation remains largely underexplored in music education, the book helps to clarify to teachers how policy thinking does shape educational action and directly influences the nature, extent, and impact of our programs. The goal is to help readers understand the complexities of policy and to become better skilled in how to think, speak, and act in policy terms. The book provides new ways to understand and therefore imagine policy, approximating it to the lives of educators and highlighting its importance and impact. This is an essential read for anyone interested in change and how to better understand decision-making within music and education. Finally, this book, while aimed at the growth of music educators' knowledge-base regarding policy, also fosters 'open thinking' regarding policy as subject, helping educators straddling arts and education to recognize that policy thinking can offer creative designs for educational change.
