Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set PDF Author:
Publisher: John Wiley & Sons
ISBN: 111953030X
Category : Science
Languages : en
Pages : 6057

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Book Description
Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set PDF Author:
Publisher: John Wiley & Sons
ISBN: 111953030X
Category : Science
Languages : en
Pages : 6057

Get Book Here

Book Description
Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

Burger's Medicinal Chemistry, Drug Discovery, and Development, Set

Burger's Medicinal Chemistry, Drug Discovery, and Development, Set PDF Author: Donald J. Abraham
Publisher: Wiley
ISBN:
Category : Science
Languages : en
Pages : 6356

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Book Description
Now in its seventh edition, Burger's Medicinal Chemistry, Drug Discovery and Development provides an established, recognized, authoritative and comprehensive source on medicinal chemistry and drug discovery and development. This flagship reference for medicinal chemists and pharmaceutical professions has been thoroughly updated and expanded across 8 volumes to incorporate the entire process of drug development (preclinical testing, clinical trials, etc.) alongside the traditional strengths in medicinal chemistry and drug discovery.

Burger's Medicinal Chemistry, Drug Discovery and Development

Burger's Medicinal Chemistry, Drug Discovery and Development PDF Author: Donald J. Abraham
Publisher:
ISBN: 9781119821465
Category : Drug development
Languages : en
Pages :

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Book Description
"Burger's is a flagship reference source for medicinal chemists and pharmaceutical professionals. This updated and expanded 8th edition has been thoroughly revised and improved to incorporate the concepts of drug hunting along with its existing coverage of the entire process of drug discovery and development. Bringing in a new and expert editorial board, this new edition updates existing chapters and adds 35 new ones, with topics including: opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures"--

Bioisosteres in Medicinal Chemistry

Bioisosteres in Medicinal Chemistry PDF Author: Nathan Brown
Publisher: John Wiley & Sons
ISBN: 3527654321
Category : Medical
Languages : en
Pages : 249

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Book Description
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.

March's Advanced Organic Chemistry

March's Advanced Organic Chemistry PDF Author: Michael B. Smith
Publisher: John Wiley & Sons
ISBN: 0470084944
Category : Science
Languages : en
Pages : 2379

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Book Description
The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations

Burger's Medicinal Chemistry

Burger's Medicinal Chemistry PDF Author: Alfred Burger
Publisher: John Wiley & Sons
ISBN:
Category : Medical
Languages : en
Pages : 520

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Book Description


The Silk Road: A Very Short Introduction

The Silk Road: A Very Short Introduction PDF Author: James A. Millward
Publisher: Oxford University Press
ISBN: 0199323852
Category : History
Languages : en
Pages : 169

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Book Description
The phrase "silk road" evokes vivid scenes of merchants leading camel caravans across vast stretches to trade exotic goods in glittering Oriental bazaars, of pilgrims braving bandits and frozen mountain passes to spread their faith across Asia. Looking at the reality behind these images, this Very Short Introduction illuminates the historical background against which the silk road flourished, shedding light on the importance of old-world cultural exchange to Eurasian and world history. On the one hand, historian James A. Millward treats the silk road broadly, to stand in for the cross-cultural communication between peoples across the Eurasian continent since at least the Neolithic era. On the other, he highlights specific examples of goods and ideas exchanged between the Mediterranean, Persia, India, and China, along with the significance of these exchanges. While including silks, spices, and travelers' tales of colorful locales, the book explains the dynamics of Central Eurasian history that promoted Silk Road interactions--especially the role of nomad empires--highlighting the importance of the biological, technological, artistic, intellectual, and religious interchanges across the continent. Millward shows that these exchanges had a profound effect on the old world that was akin to, if not on the scale of, modern globalization. He also disputes the idea that the silk road declined after the collapse of the Mongol empire or the opening of direct sea routes from Europe to Asia, showing how silk road phenomena continued through the early modern and modern expansion of the Russian and Chinese states across Central Asia. Millward concludes that the idea of the silk road has remained powerful, not only as a popular name for boutiques and restaurants, but also in modern politics and diplomacy, such as U.S. Secretary of State Hilary Clinton's "Silk Road Initiative" for India, Pakistan, and Afghanistan.

Essentials of Organic Chemistry

Essentials of Organic Chemistry PDF Author: Paul M. Dewick
Publisher: John Wiley & Sons
ISBN: 1118681967
Category : Science
Languages : en
Pages : 711

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Book Description
Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.

African Edible Insects As Alternative Source of Food, Oil, Protein and Bioactive Components

African Edible Insects As Alternative Source of Food, Oil, Protein and Bioactive Components PDF Author: Abdalbasit Adam Mariod
Publisher: Springer Nature
ISBN: 3030329526
Category : Science
Languages : en
Pages : 310

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Book Description
The harvesting, processing and consumption of edible insects is one of the main keys to the sustainability of food chains on the African continent. Insects are the largest and most successful group of animals on the planet and it is estimated that they comprise 80% of all animals. This makes edible insects extremely important to the future survival of large populations across Africa and the world. Insects offer a complete animal protein that includes all 9 essential amino acids and are very competitive with other protein sources. They are also a good source of beneficial unsaturated fats, and many insects have a perfect Omega 3:6 balance. African Edible Insects As Alternative Source of Food, Oil, Protein and Bioactive Components comprehensively outlines the importance of edible insects as food and animal feed and the processing of insects in Africa. The text also highlights indigenous knowledge of edible insects and shows the composition and nutritional value of these insects, plus presents reviews of current research and developments in this rapidly expanding field. All of the main types of edible insects are covered, including their nutritional value, chemical makeup, and harvesting and processing details. The various preparation technologies are covered for each insect, as are their individual sensory qualities and safety aspects. A key aspect of this work is its focus on the role of insects in edible oils and gelatins. Individual chapters focus on entomophagy in Africa and the various key aspects of the continent's growing edible insect consumption market. As it becomes increasingly clear that the consumption of insects will play a major role in the sustainability of food chains in Africa, this work can be used as a comprehensive and up-to-date singular source for researchers looking for a complete overview on this crucial topic.

Strategies for Organic Drug Synthesis and Design

Strategies for Organic Drug Synthesis and Design PDF Author: Daniel Lednicer
Publisher: John Wiley & Sons
ISBN: 9780470399590
Category : Science
Languages : en
Pages : 700

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Book Description
This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.