Brain Somatic Cross-Talk and the Central Control of Metabolism PDF Download
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Author: Claude Kordon
Publisher: Springer Science & Business Media
ISBN: 9783540000907
Category : Medical
Languages : en
Pages : 224
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Book Description
The present book summarizes presentations to an IPSEN Foundation Conference on Brain Somatic Cross Talk and the Central Control of Metabolism, organised in 2002. It proposes a state-of-the-art outline of the multifaceted neuronal networks which serve the highly selective purpose of adapting growth, metabolism, reproduction, and more generally energy consumption to the availability of food resources. The physiology of over twenty neurotransmitters and peptides underlying these functions is presented, together with their neuronal targets, their mechanism of action and their current or anticipated relevance for pathology. Functions covered are as diverse as regulation of food intake and sleep, adaptation to emergency situations, and finally mental disorders - as well as early, irreversible imprinting of epigenetic influences on physiological and behavioural patterns, which in some cases can even be transmitted from generation to generation. Book jacket.
Author: Claude Kordon
Publisher: Springer Science & Business Media
ISBN: 3642189997
Category : Medical
Languages : en
Pages : 200
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Book Description
In mammals, a robust physiologic system acts to maintain relative constancy of weight. A key element of this system is leptin. The nature of this "brain-somatic" cross talk is as yet poorly understood, but it is likely to have important implications for the pathophysiology and treatment of obesity, diabetes and other metabolic disorders.
Author: Hemanshu Prabhakar
Publisher: Springer
ISBN: 9789811523441
Category : Medical
Languages : en
Pages : 103
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Book Description
The central nervous system, which includes the brain and spinal cord, has a high metabolic demand. The physiology of the brain is such that it is easily affected by alterations in other systems, which in turn can compromise cerebral blood flow and oxygenation. Together the brain and spinal cord control the automatic function of our body systems. While other systems of body controls individual functions, central nervous system at the same time does many different functions, especially, controlling the function of other systems. This interaction between the brain and other systems is important when it comes to understanding how injuries to the brain can, at times, produce complications in remote organs or systems of the body, such as the lungs. This book explains the lesser-known crosstalks between acutely or chronically affected brain and lung, describing the pathophysiology of the lung following brain injury and discussing in detail the conflicts between the brain and lungs in relation to the tidal volumes, positive end-expiratory pressures, arterial carbon dioxide and oxygen levels, recruitment maneuvers and positioning, as well as potential therapeutic targets.
Author: Jean-Philippe Bastard
Publisher: Springer Science & Business Media
ISBN: 2817803434
Category : Medical
Languages : en
Pages : 432
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Book Description
The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.
Author: C. Levy-Marchal
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805594518
Category : Science
Languages : en
Pages : 105
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Book Description
Nowadays, adipose tissue is not only regarded as an organ of storage related to fuel metabolism but also as an endocrine organ involved in the regulation of insulin sensitivity, lipids and energy metabolism.These proceedings cover the nervous regulation of both white and brown adipose tissue mass. Different physiological parameters such as metabolism (lipolysis and thermogenesis) and secretory activity (leptin and other adipokines) are reviewed. The plasticity of adipose tissue (proliferation, differentiation and apoptosis) showing the presence of a neural feedback loop between adipose tissue and the brain, which plays a major role in the regulation of energy homeostasis, is discussed.Merging basic knowledge and various clinical conditions, this thorough review is of great interest to both scientists and physicians, in particular pediatricians, interested in obesity, endocrinology and nutrition.
Author: Donald W. Pfaff
Publisher: Academic Press
ISBN: 0128026677
Category : Science
Languages : en
Pages : 574
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Book Description
Principles of Hormone/Behavior Relations, Second Edition, provides an introduction to the underlying principles of endocrine regulation of behavior, a newly emerging area of research within neurobiology and endocrinology. It addresses the properties of hormone/behavior relations, including the influence of family background, timing issues, neuroanatomical features, cellular mechanisms, and the importance of environmental context and evolution. This new edition incorporates critical advances in the field, also including increased coverage of hormonal influences on food intake, and on the cardiovascular system. The addition of entirely new principles provides further coverage of epigenetics and appetite. Thoroughly revised and updated, this book is an ideal resource for neuroscientists and researchers engaging in this rapidly expanding field of study. Provides a unique structure where each chapter addresses a key principle that is illustrated by numerous basic experimental and clinical examples Includes user-friendly features, such as boxed figures with extended captions and references, numerous clinical notes, and a comprehensive list of abbreviations Contains numerous illustrations that highlight both the clinical and basic science information
Author: Shlomo Melmed
Publisher: Springer Science & Business Media
ISBN: 354073855X
Category : Medical
Languages : en
Pages : 145
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Book Description
This book covers topics that range from fundamental studies of DNA replication, chromosomal and nuclear function through growth factor control of endocrine tumor initiation and progression. The basic and translational insights gained from Hormonal Control of Cell Cycle will be of interest to those studying the biology of endocrine tumors as well as those deriving novel therapeutic approaches for these benign and malignant disorders.
Author: Robert H. Rubin
Publisher: Academic Press
ISBN: 0080958001
Category : Medical
Languages : en
Pages : 355
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Book Description
A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth.Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area. Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented) Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimer's, affective disorders) Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists
Author: Stephen Robert Bloom
Publisher:
ISBN:
Category : Gastrointestinal hormones
Languages : en
Pages : 640
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Book Description
Author: Frank P. Brooks
Publisher:
ISBN:
Category : Endocrine glands
Languages : en
Pages : 416
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Book Description
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 614
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Book Description
